ENG cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	ENG
Entrez Gene ID	771557
Full Name	endoglin
General protein information	Preferred Names endoglin Names endoglin endoglin (Osler-Rendu-Weber syndrome 1)
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001080887.1	NP_001074356.1	endoglin precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	ENG	NP_001108225.1
Mus musculus (house mouse)	Eng	NP_001139820.1
Pan troglodytes (chimpanzee)	ENG	XP_001143396.3
Gallus gallus (chicken)	ENG	NP_001074356.1
Bos taurus (cattle)	ENG	NP_001069865.1
Rattus norvegicus (Norway rat)	Eng	NP_001010968.1
Xenopus tropicalis (tropical clawed frog)	eng	XP_002935546.2
Canis lupus familiaris (dog)	ENG	XP_851469.2

Gene Ontology
Bibliography

Related articles in PubMed

Embryonic expression of the transforming growth factor beta ligand and receptor genes in chicken.
Cooley JR, Yatskievych TA, Antin PB
Developmental dynamics : an official publication of the American Association of Anatomists243(3)497-508(2014 Mar)

Characterization of chicken endoglin, a member of the zona pellucida family of proteins, and its tissue expression.
Rossi E, Langa C, Gilsanz A, Blanco FJ, Ayll?n J, Villar E, Botella LM, Caba?as C, Shaw M, Bernabeu C
Gene491(1)31-9(2012 Jan)

Dynamic expression of Endoglin, a TGF-beta co-receptor, during pre-circulation vascular development in chick.
Alev C, McIntyre BA, Ota K, Sheng G
The International journal of developmental biology54(4)737-42(2010)

Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.
Mercado-Pimentel ME, Hubbard AD, Runyan RB
Developmental biology304(1)420-32(2007 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TGFB ligands and receptors show dynamic and frequently overlapping expression patterns in numerous embryonic cell layers and structures
Title: Embryonic expression of the transforming growth factor beta ligand and receptor genes in chicken.

Transient expression of chicken endoglin allowed the identification of a 180-kDa disulfide linked homodimer similar to the mammalian homologues.
Title: Characterization of chicken endoglin, a member of the zona pellucida family of proteins, and its tissue expression.

these data reveal a dynamic expression pattern of Endoglin in pre-circulation chick development and indicate that Endoglin may play an important role in the transition from endothelial progenitors to functional endothelial cells
Title: Dynamic expression of Endoglin, a TGF-beta co-receptor, during pre-circulation vascular development in chick.

Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.
Title: Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.

The following ENG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ENG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26150	NM_001080887.1 Latest version!	Gallus gallus endoglin (ENG), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ENG ( NM_001080887.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001074356.1 Gallus gallus endoglin (ENG), mRNA.

Price & Availability↑

CloneID	OGa26150
Clone ID Related Accession (Same CDS sequence)	NM_001080887.1
Accession Version	NM_001080887.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	endoglin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY702002.1. On Jan 30, 2007 this sequence version replaced XM_001234820.1. ##Evidence-Data-START## Transcript exon combination :: AY702002.1 [ECO:0000332] ##Evidence-Data-END##

ATGTGCCGTC GGAGCTCTCC GCTGCTGCCG CTGCTGCTGG CGCTGCTCGG CCGTCCCGAC 
CCCGCTCCAG CCGAGCACTG CGACTTGCAG CCGGTGACAG CAGAGCCGCC CATCACGCTG 
TTCTACACCA CCAGCACGGT GCTGCGGGGC TGCGTCAGCA ACAGCTCTAC ATTAGCCAGC 
CATGAAGTGC ACGTCCTCAG CATCCAGTGG TCCAAGACCC CTGTCCCCAT GCTGAATGTG 
TCCATCACGC CACGGGATGA TGACTGCACC CGGCCAGCAG CACTCATCCT CCAGTGCACA 
CAGTGCTTGG CCAGCATCAC CCTCCCGTGC CAGAACCTCC TCATCCACAC TGACGCCTCT 
CTGAGACCCA AGGTGCAGGG CAAGGAGCTG CCAAAGGATG CCAAGGGACA TCTGCTGGAG 
TGGGTGCAGA GGACCTATGG GGGCATCACA TCCTACAGCG AGCTGAAGGA CCCACAGAGG 
ATCCACCTCC AGCTGGGCGA AAATAGCAAC AGCCCCCAGA ACTGCATTCC CCAGAAGGAC 
TTCGATGCCA CGCCGCATCT CGAGGCTGAG GTCCTCTTCC GTGAGGTGAA GGGCTGTACC 
AGCAGCAGTG CCCAGAGTGC CGGGGCTGCC CACATTGTCC AGCTGCTGCA CAAGCCCAGC 
TTGCCCATCA CGGAGGTGAA GCTGACCCTG AACTGCCCCA GACAGCAGCA AAACAATCAG 
ATCCTCCTCC TGCAGGGCCC GGCCAACCTC ACCTGGCTCC TGATGCTGAA CAACTGCAGC 
CTTCAGTTCC TGGCCTCCGG AACCTACAAG ATCCTGCACT TCCCCATGGA CCCACGTAAA 
GGGGAGCTGC TGCCCGACAC GGAGCAGGGC CTCATTGCCA AAGCCTTTGA GAAGAACTAC 
AGCATCATCG CCTCCTACTC CGTCATCCCC ATCAGCCCCC ACATCACACT GAATATCCAC 
GAGCGTGAGG TGCCGAAGAA GCTGCCTGTG GGGCCCACCT CGTCAGCCCC TAGCCCTGAC 
GACGTGTCTA GCAGTCTGCT CTTCACGCTC AGTCCCTGGA AGTGCACGGA TGACACCATG 
GAAATCGTCA TCGCCAGGTC CAACCTGGAG CCCATCAAGG ACGTGGTGAA CATCACCCTG 
CGGGACATCA GCTGCCAGGC TGAGAAGAAC GCCACACACT TCATGCTGCA CACCCTGCTC 
AGCCACTGCG GCACCTCGCT GGAGAACCAC GGCCATGCCA ACAACGAGTT CGTCCTCAGC 
CTGTCCAAGG GCTCGGTGCT CAGGAGCGTG CGGGTGGCCT TCCAGTGCCC GATCCCACGG 
GAGCTCTTCC TGCGCCTCTT CCCCTCCGCC GCCTTCAAGG CACCGCAGAC AGAGCTGGAG 
GTCAACAAGG AGGTGTTTGT GCAGGCATCC ATGCACTTGG AGGACTACCC GGCCGACCTG 
CAGCTCAAGG AGTGCTACCT GATGGCCCCC GGCATGGAGC CGCTGCTGCT GGTGCAGGGC 
AACAAGGCGC AGAGCTCCAG CGTGGCCATG CTGGAGGAGC CCCCCAGCAA CCGGGCCAGG 
AAGGTCTGGC GCTTCCGCTT CACCTACACC GTCCCCGAGG GCAGGCACGT CCCCTTCTCC 
GCCACCCTCA AGTGCAAGGC TGGGCTGCAG AACAACACCA TCTTCGAGAA GGTTTTGGAA 
GTGAAGGTGA AGGACGTCTG GCGGCTGCCC AACAACCAAG GGCTGGGGCT GTCCGCCGTG 
CTGGGCATCA CCTTTGGAGC CTTCCTCATC GGCGCACTCC TCACTGCTGG GCTCTGGTAT 
ATCTACTCGC ATACCCGTCC CATCTCCAAA CTGCAGCCGG TTTCCACCAC AGCACCAGCC 
TCGGAGAGCA GCAGCACCAA CCACAGCATT GGCAGCACCC AGAGCACCCC CTGCTCCACC 
AGCAGCATGG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074356.1
CDS	1..1935
Translation	MCRRSSPLLPLLLALLGRPDPAPAEHCDLQPVTAEPPITLFYTTSTVLRGCVSNSSTLASHEVHVLSIQWSKTPVPMLNVSITPRDDDCTRPAALILQCTQCLASITLPCQNLLIHTDASLRPKVQGKELPKDAKGHLLEWVQRTYGGITSYSELKDPQRIHLQLGENSNSPQNCIPQKDFDATPHLEAEVLFREVKGCTSSSAQSAGAAHIVQLLHKPSLPITEVKLTLNCPRQQQNNQILLLQGPANLTWLLMLNNCSLQFLASGTYKILHFPMDPRKGELLPDTEQGLIAKAFEKNYSIIASYSVIPISPHITLNIHEREVPKKLPVGPTSSAPSPDDVSSSLLFTLSPWKCTDDTMEIVIARSNLEPIKDVVNITLRDISCQAEKNATHFMLHTLLSHCGTSLENHGHANNEFVLSLSKGSVLRSVRVAFQCPIPRELFLRLFPSAAFKAPQTELEVNKEVFVQASMHLEDYPADLQLKECYLMAPGMEPLLLVQGNKAQSSSVAMLEEPPSNRARKVWRFRFTYTVPEGRHVPFSATLKCKAGLQNNTIFEKVLEVKVKDVWRLPNNQGLGLSAVLGITFGAFLIGALLTAGLWYIYSHTRPISKLQPVSTTAPASESSSTNHSIGSTQSTPCSTSSMA

Target ORF information:

RefSeq Version	NM_001080887.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus endoglin (ENG), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080887.1

ORF Insert Sequence:

ATGTGCCGTC GGAGCTCTCC GCTGCTGCCG CTGCTGCTGG CGCTGCTCGG CCGTCCCGAC 
CCCGCTCCAG CCGAGCACTG CGACTTGCAG CCGGTGACAG CAGAGCCGCC CATCACGCTG 
TTCTACACCA CCAGCACGGT GCTGCGGGGC TGCGTCAGCA ACAGCTCTAC ATTAGCCAGC 
CATGAAGTGC ACGTCCTCAG CATCCAGTGG TCCAAGACCC CTGTCCCCAT GCTGAATGTG 
TCCATCACGC CACGGGATGA TGACTGCACC CGGCCAGCAG CACTCATCCT CCAGTGCACA 
CAGTGCTTGG CCAGCATCAC CCTCCCGTGC CAGAACCTCC TCATCCACAC TGACGCCTCT 
CTGAGACCCA AGGTGCAGGG CAAGGAGCTG CCAAAGGATG CCAAGGGACA TCTGCTGGAG 
TGGGTGCAGA GGACCTATGG GGGCATCACA TCCTACAGCG AGCTGAAGGA CCCACAGAGG 
ATCCACCTCC AGCTGGGCGA AAATAGCAAC AGCCCCCAGA ACTGCATTCC CCAGAAGGAC 
TTCGATGCCA CGCCGCATCT CGAGGCTGAG GTCCTCTTCC GTGAGGTGAA GGGCTGTACC 
AGCAGCAGTG CCCAGAGTGC CGGGGCTGCC CACATTGTCC AGCTGCTGCA CAAGCCCAGC 
TTGCCCATCA CGGAGGTGAA GCTGACCCTG AACTGCCCCA GACAGCAGCA AAACAATCAG 
ATCCTCCTCC TGCAGGGCCC GGCCAACCTC ACCTGGCTCC TGATGCTGAA CAACTGCAGC 
CTTCAGTTCC TGGCCTCCGG AACCTACAAG ATCCTGCACT TCCCCATGGA CCCACGTAAA 
GGGGAGCTGC TGCCCGACAC GGAGCAGGGC CTCATTGCCA AAGCCTTTGA GAAGAACTAC 
AGCATCATCG CCTCCTACTC CGTCATCCCC ATCAGCCCCC ACATCACACT GAATATCCAC 
GAGCGTGAGG TGCCGAAGAA GCTGCCTGTG GGGCCCACCT CGTCAGCCCC TAGCCCTGAC 
GACGTGTCTA GCAGTCTGCT CTTCACGCTC AGTCCCTGGA AGTGCACGGA TGACACCATG 
GAAATCGTCA TCGCCAGGTC CAACCTGGAG CCCATCAAGG ACGTGGTGAA CATCACCCTG 
CGGGACATCA GCTGCCAGGC TGAGAAGAAC GCCACACACT TCATGCTGCA CACCCTGCTC 
AGCCACTGCG GCACCTCGCT GGAGAACCAC GGCCATGCCA ACAACGAGTT CGTCCTCAGC 
CTGTCCAAGG GCTCGGTGCT CAGGAGCGTG CGGGTGGCCT TCCAGTGCCC GATCCCACGG 
GAGCTCTTCC TGCGCCTCTT CCCCTCCGCC GCCTTCAAGG CACCGCAGAC AGAGCTGGAG 
GTCAACAAGG AGGTGTTTGT GCAGGCATCC ATGCACTTGG AGGACTACCC GGCCGACCTG 
CAGCTCAAGG AGTGCTACCT GATGGCCCCC GGCATGGAGC CGCTGCTGCT GGTGCAGGGC 
AACAAGGCGC AGAGCTCCAG CGTGGCCATG CTGGAGGAGC CCCCCAGCAA CCGGGCCAGG 
AAGGTCTGGC GCTTCCGCTT CACCTACACC GTCCCCGAGG GCAGGCACGT CCCCTTCTCC 
GCCACCCTCA AGTGCAAGGC TGGGCTGCAG AACAACACCA TCTTCGAGAA GGTTTTGGAA 
GTGAAGGTGA AGGACGTCTG GCGGCTGCCC AACAACCAAG GGCTGGGGCT GTCCGCCGTG 
CTGGGCATCA CCTTTGGAGC CTTCCTCATC GGCGCACTCC TCACTGCTGG GCTCTGGTAT 
ATCTACTCGC ATACCCGTCC CATCTCCAAA CTGCAGCCGG TTTCCACCAC AGCACCAGCC 
TCGGAGAGCA GCAGCACCAA CCACAGCATT GGCAGCACCC AGAGCACCCC CTGCTCCACC 
AGCAGCATGG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Embryonic expression of the transforming growth factor beta ligand and receptor genes in chicken.
Developmental dynamics : an official publication of the American Association of Anatomists243(3)497-508(2014 Mar)
Cooley JR,Yatskievych TA,Antin PB

Characterization of chicken endoglin, a member of the zona pellucida family of proteins, and its tissue expression.
Gene491(1)31-9(2012 Jan)
Rossi E,Langa C,Gilsanz A,Blanco FJ,Ayll?n J,Villar E,Botella LM,Caba?as C,Shaw M,Bernabeu C

Dynamic expression of Endoglin, a TGF-beta co-receptor, during pre-circulation vascular development in chick.
The International journal of developmental biology54(4)737-42(2010)
Alev C,McIntyre BA,Ota K,Sheng G

Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.
Developmental biology304(1)420-32(2007 Apr)
Mercado-Pimentel ME,Hubbard AD,Runyan RB