DBN1 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	DBN1
Entrez Gene ID	396496
Full Name	drebrin 1
General protein information	Preferred Names drebrin 1 Names drebrin developmentally regulated brain protein drebrin A
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205499.1	NP_990830.1	drebrin

Pathways from BioSystems

Homologies

Bos taurus (cattle)	DBN1	NP_001039382.1
Mus musculus (house mouse)	Dbn1	NP_001170842.1
Xenopus tropicalis (tropical clawed frog)	dbn1	NP_001039142.1
Rattus norvegicus (Norway rat)	Dbn1	NP_112286.1
Canis lupus familiaris (dog)	DBN1	XP_546204.3
Homo sapiens (human)	DBN1	NP_004386.2
	DBN1	XP_001091175.1
Gallus gallus (chicken)	DBN1	NP_990830.1
Danio rerio (zebrafish)	LOC561153	XP_005173939.1
Pan troglodytes (chimpanzee)	DBN1	XP_518132.2

Gene Ontology
Bibliography

Related articles in PubMed

Molecular Cloning of Drebrin: Progress and Perspectives.
Kojima N
Advances in experimental medicine and biology100625-36(2017)

Localization of Drebrin: Light Microscopy Study.
Shirao T, Koganezawa N, Yamazaki H, Hanamura K, Imamura K
Advances in experimental medicine and biology1006105-118(2017)

Molecular cloning of a developmentally regulated brain protein, chicken drebrin A and its expression by alternative splicing of the drebrin gene.
Kojima N, Shirao T, Obata K
Brain research. Molecular brain research19(1-2)101-14(1993 Jul)

Nucleotide sequences of two embryonic drebrins, developmentally regulated brain proteins, and developmental change in their mRNAs.
Kojima N, Kato Y, Shirao T, Obata K
Brain research464(3)207-15(1988 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chicken drebrin are now classified into three isoforms, namely, drebrins E1, E2, and A. Genomic cloning demonstrated that the three isoforms are generated by an alternative splicing of individual exons encoding the insertion sequences from single drebrin gene
Title: Molecular Cloning of Drebrin: Progress and Perspectives.

In the adult brain, drebrin is mainly localized in dendritic spines, but in some nuclei, drebrin can be detected in neuronal somata as well as dendritic spines. The fact that the developmental changes in drebrin expression highly correlate in time with the sensitive period of visual cortical plasticity in kittens suggests that synaptic plasticity depends on drebrin.
Title: Localization of Drebrin: Light Microscopy Study.

The following DBN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DBN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27663	NM_205499.1 Latest version!	Gallus gallus drebrin 1 (DBN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$342.30 $489.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DBN1 ( NM_205499.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990830.1 Gallus gallus drebrin 1 (DBN1), mRNA.

Price & Availability↑

CloneID	OGa27663
Clone ID Related Accession (Same CDS sequence)	NM_205499.1
Accession Version	NM_205499.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1824bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Gallus gallus(chicken)
Product	drebrin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M36961.1. On Dec 9, 2006 this sequence version replaced XM_001236429.1. ##Evidence-Data-START## Transcript exon combination :: M36961.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCTGGCG TCGGCTTCGC GGCGCACCGC CTGGAGCTGC TCGCCTCCTA CCAGGACGTG 
ATCGGCGAGG ACAGCCCCAC CGACTGGGCC CTCTACACGT ATGAGGATGG CTCTGATGAC 
CTGAAGCTGG CAGCATCAGG AGGAGGGGGT CTGCTGGAGC TCTCTGGGCA CTTTGAGATC 
CAGAAGGTGA TGTACGGCTT CTGCAGCGTC AAGGAGCCCC AGGCCGTGCT CCCCAAATAT 
GTCCTTGTCA ATTGGGTGGG TGAGGATGTG CCTGACGCCC GCAAATGTGC CTGTGCCAGC 
CACGTGGCCA AGATCGCAGA GTTCTTCCAG GGTGTGGATG TTATCGTCAA TGCCAGCAGC 
GTGGAGGACA TTGACCCGGG GGCCATCGGG CAGCGGCTCT CCAACGGGCT GGCGCGCGTC 
TCCAGCCCCG TGCTGCACCG CCTGCGGCTG CGTGAGGACG AGAATGCCGA GCCCGTGGGC 
ACGACCTACC AGAAAACCGA CGCCACCGTG GAGATGAAGC GGCTCAACCG GGAGCAGTTC 
TGGGAACAAG CCAAGAAAGA GGAGGAGTTG CGCAAGGAGG AGGAGAGGAA AAAGGCGTTG 
GATGCGCGGC TGCGGTTCGA GCAGGAGCGC ATGGAGCAGG AGCGGCTGGA GCAGGAGGAG 
CGCGAGAGGC GCTACCGGGA GCGCGAGGAG CAGATCGAGG AGCACAGGAG GAAGCAGCAG 
AGCATGGAGG CGGAGGAGGC CCGGCAGCGC CTGAAGGAGC AGTCCATCTT TGGGGAGCAG 
CAAGAGGAGG ACGACAGGCA GCAGCTCCGG AAATCAGAGT CAGAGGTGGA GGAGGCCGCT 
GCCATCATTG CCCAGCGACC TGACAACCCC CGGGAGTTCT TCAAGCAGCA GGAGCGGGTG 
GCATCGGGCA GCGGCGACGC CATCTCGCCG GGCAGCCATA GGACAGGCAG CCAGTCCGAC 
TACCGAAAGG TTTCGGCAGC GGGCTGCAGC CCCTGCGAGT CCAGCCCGGC CTCCACGCCG 
CTGGGCGAGC AGCGCACCCG CGCCCCGGCC GAAGAGACGC CGGCAACGCC CAAAGACTCC 
CCCAGCCCCA GCACCCAGGT GGCAGAGCCG GCAGCGACTG AGCAGCACTG GCCCTTCCCT 
GGGCCTGAAG ACAAAGCTGC AGAGCCGCCG GGGGACGAGC CCGACCCCGA CCCCAGGCCG 
GCGTGGACAG CGGGGGCTGA CGTGCTGGGG GACCTGGTGA CCCTGGAGCC CTCCGAGCCA 
TCCCCAGCGC CCGCTGCGTC CGAACCCCAG CCCGTGGAGA CACCCGGTGT GGCCGAGCCC 
CTCATCGAGC TGTGGCAGAG TGATGGCGCG GCCCCCGCTG CCACCAGCAC CTGGCCCCTG 
CCCGACACCC CCGCGGGACC ACCGGTCCCC CCCGAGGAGG GCACGCTGCT GGGCCTGGAC 
GAGCTGCCCG AGCCCCCCGC CACCTTCTGT GACGCGGAGC AGCACGAGGA GGTGGAAGAA 
GAAGAAGAGG AGGAGGAGGA GGCCACAGCG GGTGAGCCCC ATCCCACAGG GCTGGGCTAC 
CAGGAGGGCT ACCAAGAAGG CCCCGAGGTG CCCCCCATCA CCAATGGGGA GATGGGCCCC 
AAGGACGGCA CGGCGGGCCG TGGCGAGCAG GCCAGCGAGG GCTACTTCAG CCAGTCCCAG 
GAGGAGGAGG CCCCGCCGCC CGAGGAGCCG TCGGCCAAAG CCCCGCAGCC CGTCTTCTAC 
AACAAGCCGC CAGAGATCGA CATCACGTGC TGGGACACGG ACCCGCTGCC CGAGGAGGAG 
GAGAGCTTCG GGGGCGGCCT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990830.1
CDS	60..1883
Translation	MAGVGFAAHRLELLASYQDVIGEDSPTDWALYTYEDGSDDLKLAASGGGGLLELSGHFEIQKVMYGFCSVKEPQAVLPKYVLVNWVGEDVPDARKCACASHVAKIAEFFQGVDVIVNASSVEDIDPGAIGQRLSNGLARVSSPVLHRLRLREDENAEPVGTTYQKTDATVEMKRLNREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERLEQEERERRYREREEQIEEHRRKQQSMEAEEARQRLKEQSIFGEQQEEDDRQQLRKSESEVEEAAAIIAQRPDNPREFFKQQERVASGSGDAISPGSHRTGSQSDYRKVSAAGCSPCESSPASTPLGEQRTRAPAEETPATPKDSPSPSTQVAEPAATEQHWPFPGPEDKAAEPPGDEPDPDPRPAWTAGADVLGDLVTLEPSEPSPAPAASEPQPVETPGVAEPLIELWQSDGAAPAATSTWPLPDTPAGPPVPPEEGTLLGLDELPEPPATFCDAEQHEEVEEEEEEEEEATAGEPHPTGLGYQEGYQEGPEVPPITNGEMGPKDGTAGRGEQASEGYFSQSQEEEAPPPEEPSAKAPQPVFYNKPPEIDITCWDTDPLPEEEESFGGGL

Target ORF information:

RefSeq Version	NM_205499.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus drebrin 1 (DBN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205499.1

ORF Insert Sequence:

ATGGCTGGCG TCGGCTTCGC GGCGCACCGC CTGGAGCTGC TCGCCTCCTA CCAGGACGTG 
ATCGGCGAGG ACAGCCCCAC CGACTGGGCC CTCTACACGT ATGAGGATGG CTCTGATGAC 
CTGAAGCTGG CAGCATCAGG AGGAGGGGGT CTGCTGGAGC TCTCTGGGCA CTTTGAGATC 
CAGAAGGTGA TGTACGGCTT CTGCAGCGTC AAGGAGCCCC AGGCCGTGCT CCCCAAATAT 
GTCCTTGTCA ATTGGGTGGG TGAGGATGTG CCTGACGCCC GCAAATGTGC CTGTGCCAGC 
CACGTGGCCA AGATCGCAGA GTTCTTCCAG GGTGTGGATG TTATCGTCAA TGCCAGCAGC 
GTGGAGGACA TTGACCCGGG GGCCATCGGG CAGCGGCTCT CCAACGGGCT GGCGCGCGTC 
TCCAGCCCCG TGCTGCACCG CCTGCGGCTG CGTGAGGACG AGAATGCCGA GCCCGTGGGC 
ACGACCTACC AGAAAACCGA CGCCACCGTG GAGATGAAGC GGCTCAACCG GGAGCAGTTC 
TGGGAACAAG CCAAGAAAGA GGAGGAGTTG CGCAAGGAGG AGGAGAGGAA AAAGGCGTTG 
GATGCGCGGC TGCGGTTCGA GCAGGAGCGC ATGGAGCAGG AGCGGCTGGA GCAGGAGGAG 
CGCGAGAGGC GCTACCGGGA GCGCGAGGAG CAGATCGAGG AGCACAGGAG GAAGCAGCAG 
AGCATGGAGG CGGAGGAGGC CCGGCAGCGC CTGAAGGAGC AGTCCATCTT TGGGGAGCAG 
CAAGAGGAGG ACGACAGGCA GCAGCTCCGG AAATCAGAGT CAGAGGTGGA GGAGGCCGCT 
GCCATCATTG CCCAGCGACC TGACAACCCC CGGGAGTTCT TCAAGCAGCA GGAGCGGGTG 
GCATCGGGCA GCGGCGACGC CATCTCGCCG GGCAGCCATA GGACAGGCAG CCAGTCCGAC 
TACCGAAAGG TTTCGGCAGC GGGCTGCAGC CCCTGCGAGT CCAGCCCGGC CTCCACGCCG 
CTGGGCGAGC AGCGCACCCG CGCCCCGGCC GAAGAGACGC CGGCAACGCC CAAAGACTCC 
CCCAGCCCCA GCACCCAGGT GGCAGAGCCG GCAGCGACTG AGCAGCACTG GCCCTTCCCT 
GGGCCTGAAG ACAAAGCTGC AGAGCCGCCG GGGGACGAGC CCGACCCCGA CCCCAGGCCG 
GCGTGGACAG CGGGGGCTGA CGTGCTGGGG GACCTGGTGA CCCTGGAGCC CTCCGAGCCA 
TCCCCAGCGC CCGCTGCGTC CGAACCCCAG CCCGTGGAGA CACCCGGTGT GGCCGAGCCC 
CTCATCGAGC TGTGGCAGAG TGATGGCGCG GCCCCCGCTG CCACCAGCAC CTGGCCCCTG 
CCCGACACCC CCGCGGGACC ACCGGTCCCC CCCGAGGAGG GCACGCTGCT GGGCCTGGAC 
GAGCTGCCCG AGCCCCCCGC CACCTTCTGT GACGCGGAGC AGCACGAGGA GGTGGAAGAA 
GAAGAAGAGG AGGAGGAGGA GGCCACAGCG GGTGAGCCCC ATCCCACAGG GCTGGGCTAC 
CAGGAGGGCT ACCAAGAAGG CCCCGAGGTG CCCCCCATCA CCAATGGGGA GATGGGCCCC 
AAGGACGGCA CGGCGGGCCG TGGCGAGCAG GCCAGCGAGG GCTACTTCAG CCAGTCCCAG 
GAGGAGGAGG CCCCGCCGCC CGAGGAGCCG TCGGCCAAAG CCCCGCAGCC CGTCTTCTAC 
AACAAGCCGC CAGAGATCGA CATCACGTGC TGGGACACGG ACCCGCTGCC CGAGGAGGAG 
GAGAGCTTCG GGGGCGGCCT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Molecular Cloning of Drebrin: Progress and Perspectives.
Advances in experimental medicine and biology100625-36(2017)
Kojima N

Localization of Drebrin: Light Microscopy Study.
Advances in experimental medicine and biology1006105-118(2017)
Shirao T,Koganezawa N,Yamazaki H,Hanamura K,Imamura K

Molecular cloning of a developmentally regulated brain protein, chicken drebrin A and its expression by alternative splicing of the drebrin gene.
Brain research. Molecular brain research19(1-2)101-14(1993 Jul)
Kojima N,Shirao T,Obata K

Nucleotide sequences of two embryonic drebrins, developmentally regulated brain proteins, and developmental change in their mRNAs.
Brain research464(3)207-15(1988 Nov)
Kojima N,Kato Y,Shirao T,Obata K