gfra1b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	gfra1b
Entrez Gene ID	79377
Full Name	gdnf family receptor alpha 1b
Synonyms	gfralpha1b
General protein information	Preferred Names gdnf family receptor alpha 1b Names GDNF family receptor alpha-1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_131731.1	NP_571806.1	GDNF family receptor alpha-1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	GFRA1	NP_005255.1
Pan troglodytes (chimpanzee)	GFRA1	XP_001150668.1
Danio rerio (zebrafish)	gfra1a	NP_571805.1
Danio rerio (zebrafish)	gfra1b	NP_571806.1
Canis lupus familiaris (dog)	GFRA1	XP_005637819.1
Mus musculus (house mouse)	Gfra1	NP_034409.1
Rattus norvegicus (Norway rat)	Gfra1	NP_037091.1
Xenopus tropicalis (tropical clawed frog)	gfra1	NP_001096555.1
Bos taurus (cattle)	GFRA1	NP_001098881.1
Gallus gallus (chicken)	GFRA1	NP_990433.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of neurexin2a in lead-induced locomotor defect in developing zebrafish.
Tu H, Peng T, Liu J, Chen X, Fan C, Huang Z, Zhang Y, Zou F, Meng X
Aquatic toxicology (Amsterdam, Netherlands)194167-175(2018 Jan)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Glial cell line-derived neurotrophic factor defines the path of developing and regenerating axons in the lateral line system of zebrafish.
Schuster K, Dambly-Chaudi?re C, Ghysen A
Proceedings of the National Academy of Sciences of the United States of America107(45)19531-6(2010 Nov)

Distribution of glial cell line-derived neurotrophic factor receptor alpha-1 in the brain of adult zebrafish.
Lucini C, Carla L, Facello B, Bruna F, Maruccio L, Lucianna M, Langellotto F, Fernanda L, Sordino P, Paolo S, Castaldo L, Luciana C
Journal of anatomy217(2)174-85(2010 Aug)

Glial cell line-derived neurotrophic factor in Purkinje cells of adult zebrafish: an autocrine mode of action?
Facello B, Castaldo L, De Martino L, Lucini C
Neuroscience letters465(2)133-7(2009 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following gfra1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the gfra1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa31695	NM_131731.1 Latest version!	Danio rerio gdnf family receptor alpha 1b (gfra1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

gfra1b ( NM_131731.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571806.1 Danio rerio gdnf family receptor alpha 1b (gfra1b), mRNA.

Price & Availability↑

CloneID	ODa31695
Clone ID Related Accession (Same CDS sequence)	NM_131731.1
Accession Version	NM_131731.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1446bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-12
Organism	Danio rerio(zebrafish)
Product	GDNF family receptor alpha-1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY436321.1. ##Evidence-Data-START## Transcript exon combination :: AY436321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168447, SAMEA3505370 [ECO:0000348] ##Evidence-Data-END##

ATGGATCTGA ATAAAGCGAC GATGATATTC GCAACTTTTT GGATAATGTT TCCTGTGCTT 
GATTTAGTGC ACTTCTCAAA GGCAGATGCG ATCGCACAGT CTCGCTCGGT TCGGCTGGAC 
TGCGTTAGGG CTCATGAACA GTGTTTGGGA AAGTACGGAT GCAGCACCAA GTACCGCACT 
ATGAGACAGT GTGTTGCCGG GAGAACCGGT AACTTCAGCA TGAAGGGCGA ACCAGAGGCG 
CAGGACGAGT GCAGGAACGC CATAGAGTCG ATGAAACAGA GTCCTCTGTA TGACTGCAAG 
TGCAGGAGAG GAATGAAGAA AGAAAAGAAC TGCCTGCGCA TCTTCTGGAG TATATATCAA 
AGTTTACAGG CTAATGACTT ATTGGAAGAC TCGCCATATG AGCCCGTAAA CAGCCGTCTG 
TCTGATATTT TTCGTCTGGC TCCCATCATA TCAGGTGAAG CGGCCTTTAC CAAGGACAAC 
AACTGCCTGA ATGCTGCCAA GGCCTGCAAC CTGAATGACA CATGTAAGAA GTACCGCTCC 
TTGTACATCA GCCCCTGCAC CAGTCGAGTC TCCACTACTG AAGTGTGTAA CAAGCGCAAG 
TGCCACAAGG CCCTGCGGCA GTTCTTCGAC AAGGTGCCAC CGAAGCATAG CTATGGCATG 
CTTTTCTGCT CCTGCCCCTC CGGGGATCAT TCGGCTTGCT CCGAGCGCAG ACGTCAGACC 
ATCGTGCCAG CCTGCTCCTA CGAGGACAAG GAAAAGCCCA ACTGTCTCTC CTTGCAAGCC 
TCCTGCAAGA CCAACTACAT CTGCAGATCT CGTTTAGCTG ACTTCCTCAC TAACTGTCAA 
CCTGAGGCCC GCTCGATATC AGGGTGTCTG AAGGAAAACT ATGCTGACTG TCTGCTGGCA 
TATTCAGGGC TCATTGGTAC GGTGATGACC CCGAACTACC TCCGCGCACC TGGCATCAGC 
GTGTCACCTT GGTGTGACTG TAGTAACAGC GGAAACGGAA AAGCAGAGTG TGACAAGTTC 
ACCGAGTTTT TCACCAACAA CCGTTGTCTC CGCAATGCCA TCCAGGCATT YGGCAAYGGC 
ACAGATGTAG GAGTGTGGCA ACCCCAACCA CCCATCATGT CCACTCCAGC TGACCCCTAC 
ACCCCCCCAA AAGGACGCGA CAGGACATCC AACGCCCTGG ATGACCCAAC ACTCACCAAT 
GACCTCGACA GCAATGCAGA CCATCTCTAC AGCTTCTGTG GAAGCCTGCA GGCTCAGAAA 
CTGAAAAGCA ATGTTACTCT GGACGTTCTT TGTGTGGATC AGCAGCTGAA TGACCCCAGT 
AGCTTTAATG CAATCACTCG GAGCTCGACT AGTGCTGTCT GTCTGGTGGA CTGGACTGTT 
CTTCTGCTGC TGTCTCTGCT CTCAATTCTT CACCTCGACC ATCTTACAGC CTCACAAACT 
GTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571806.1
CDS	1..1446
Translation	MDLNKATMIFATFWIMFPVLDLVHFSKADAIAQSRSVRLDCVRAHEQCLGKYGCSTKYRTMRQCVAGRTGNFSMKGEPEAQDECRNAIESMKQSPLYDCKCRRGMKKEKNCLRIFWSIYQSLQANDLLEDSPYEPVNSRLSDIFRLAPIISGEAAFTKDNNCLNAAKACNLNDTCKKYRSLYISPCTSRVSTTEVCNKRKCHKALRQFFDKVPPKHSYGMLFCSCPSGDHSACSERRRQTIVPACSYEDKEKPNCLSLQASCKTNYICRSRLADFLTNCQPEARSISGCLKENYADCLLAYSGLIGTVMTPNYLRAPGISVSPWCDCSNSGNGKAECDKFTEFFTNNRCLRNAIQAnullGnullGTDVGVWQPQPPIMSTPADPYTPPKGRDRTSNALDDPTLTNDLDSNADHLYSFCGSLQAQKLKSNVTLDVLCVDQQLNDPSSFNAITRSSTSAVCLVDWTVLLLLSLLSILHLDHLTASQTV

Target ORF information:

RefSeq Version	NM_131731.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio gdnf family receptor alpha 1b (gfra1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131731.1

ORF Insert Sequence:

ATGGATCTGA ATAAAGCGAC GATGATATTC GCAACTTTTT GGATAATGTT TCCTGTGCTT 
GATTTAGTGC ACTTCTCAAA GGCAGATGCG ATCGCACAGT CTCGCTCGGT TCGGCTGGAC 
TGCGTTAGGG CTCATGAACA GTGTTTGGGA AAGTACGGAT GCAGCACCAA GTACCGCACT 
ATGAGACAGT GTGTTGCCGG GAGAACCGGT AACTTCAGCA TGAAGGGCGA ACCAGAGGCG 
CAGGACGAGT GCAGGAACGC CATAGAGTCG ATGAAACAGA GTCCTCTGTA TGACTGCAAG 
TGCAGGAGAG GAATGAAGAA AGAAAAGAAC TGCCTGCGCA TCTTCTGGAG TATATATCAA 
AGTTTACAGG CTAATGACTT ATTGGAAGAC TCGCCATATG AGCCCGTAAA CAGCCGTCTG 
TCTGATATTT TTCGTCTGGC TCCCATCATA TCAGGTGAAG CGGCCTTTAC CAAGGACAAC 
AACTGCCTGA ATGCTGCCAA GGCCTGCAAC CTGAATGACA CATGTAAGAA GTACCGCTCC 
TTGTACATCA GCCCCTGCAC CAGTCGAGTC TCCACTACTG AAGTGTGTAA CAAGCGCAAG 
TGCCACAAGG CCCTGCGGCA GTTCTTCGAC AAGGTGCCAC CGAAGCATAG CTATGGCATG 
CTTTTCTGCT CCTGCCCCTC CGGGGATCAT TCGGCTTGCT CCGAGCGCAG ACGTCAGACC 
ATCGTGCCAG CCTGCTCCTA CGAGGACAAG GAAAAGCCCA ACTGTCTCTC CTTGCAAGCC 
TCCTGCAAGA CCAACTACAT CTGCAGATCT CGTTTAGCTG ACTTCCTCAC TAACTGTCAA 
CCTGAGGCCC GCTCGATATC AGGGTGTCTG AAGGAAAACT ATGCTGACTG TCTGCTGGCA 
TATTCAGGGC TCATTGGTAC GGTGATGACC CCGAACTACC TCCGCGCACC TGGCATCAGC 
GTGTCACCTT GGTGTGACTG TAGTAACAGC GGAAACGGAA AAGCAGAGTG TGACAAGTTC 
ACCGAGTTTT TCACCAACAA CCGTTGTCTC CGCAATGCCA TCCAGGCATT YGGCAAYGGC 
ACAGATGTAG GAGTGTGGCA ACCCCAACCA CCCATCATGT CCACTCCAGC TGACCCCTAC 
ACCCCCCCAA AAGGACGCGA CAGGACATCC AACGCCCTGG ATGACCCAAC ACTCACCAAT 
GACCTCGACA GCAATGCAGA CCATCTCTAC AGCTTCTGTG GAAGCCTGCA GGCTCAGAAA 
CTGAAAAGCA ATGTTACTCT GGACGTTCTT TGTGTGGATC AGCAGCTGAA TGACCCCAGT 
AGCTTTAATG CAATCACTCG GAGCTCGACT AGTGCTGTCT GTCTGGTGGA CTGGACTGTT 
CTTCTGCTGC TGTCTCTGCT CTCAATTCTT CACCTCGACC ATCTTACAGC CTCACAAACT 
GTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of neurexin2a in lead-induced locomotor defect in developing zebrafish.
Aquatic toxicology (Amsterdam, Netherlands)194167-175(2018 Jan)
Tu H,Peng T,Liu J,Chen X,Fan C,Huang Z,Zhang Y,Zou F,Meng X

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Glial cell line-derived neurotrophic factor defines the path of developing and regenerating axons in the lateral line system of zebrafish.
Proceedings of the National Academy of Sciences of the United States of America107(45)19531-6(2010 Nov)
Schuster K,Dambly-Chaudi?re C,Ghysen A

Distribution of glial cell line-derived neurotrophic factor receptor alpha-1 in the brain of adult zebrafish.
Journal of anatomy217(2)174-85(2010 Aug)
Lucini C,Carla L,Facello B,Bruna F,Maruccio L,Lucianna M,Langellotto F,Fernanda L,Sordino P,Paolo S,Castaldo L,Luciana C

Glial cell line-derived neurotrophic factor in Purkinje cells of adult zebrafish: an autocrine mode of action?
Neuroscience letters465(2)133-7(2009 Nov)
Facello B,Castaldo L,De Martino L,Lucini C