lrrc8c cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	lrrc8c
Entrez Gene ID	571216
Full Name	leucine rich repeat containing 8 VRAC subunit C
Synonyms	fc22f12,wu:fc22f12
General protein information	Preferred Names leucine rich repeat containing 8 VRAC subunit C Names leucine-rich repeat-containing protein 8C leucine rich repeat containing 8 family, member C
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001326544.1	NP_001313473.1	leucine-rich repeat-containing protein 8C

Pathways from BioSystems

Homologies

Homo sapiens (human)	LRRC8C	NP_115646.2
Danio rerio (zebrafish)	lrrc8c	XP_001919381.1
Pan troglodytes (chimpanzee)	LRRC8C	XP_513550.2
	LRRC8C	XP_001087650.1
Bos taurus (cattle)	LRRC8C	NP_001092509.1
Rattus norvegicus (Norway rat)	Lrrc8c	NP_001032256.1
Canis lupus familiaris (dog)	LRRC8C	XP_547289.2
Gallus gallus (chicken)	LRRC8C	XP_422353.2
Mus musculus (house mouse)	Lrrc8c	NP_598658.1
Xenopus tropicalis (tropical clawed frog)	lrrc8c	XP_004913784.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, Livstone MS, Lewis SE, Thomas PD
Briefings in bioinformatics12(5)449-62(2011 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following lrrc8c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lrrc8c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa11764	NM_001326544.1 Latest version!	Danio rerio leucine rich repeat containing 8 VRAC subunit C (lrrc8c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

lrrc8c ( NM_001326544.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001313473.1 Danio rerio leucine rich repeat containing 8 VRAC subunit C (lrrc8c), mRNA.

Price & Availability↑

CloneID	ODa11764
Clone ID Related Accession (Same CDS sequence)	NM_001326544.1
Accession Version	NM_001326544.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2379bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	leucine-rich repeat-containing protein 8C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU928017.7 and CR790380.8. On May 20, 2016 this sequence version replaced XM_001919346.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: GDQH01003217.1, GFIL01025502.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168447, SAMEA2168448 [ECO:0000348] ##Evidence-Data-END##

ATGATTCCAG TGACTGAATT CCGGCAGTTC ACGGAACAGC AGCCAGCGTT CCGGGTTCTG 
AAGCCATGGT GGGACGTGTT CACAGACTAC CTCTCTGTGG TCATGCTTAT GATAGGCGTG 
TTTGGATGCA CTCTGCAGGT GATGCAGGAC AAAATCATAT GCCTTCCTCA AAGGACATTC 
TCTACAAACC AGACAGAGCT GATGTGCCCT CCTCCTTCTT CAAATCAGGT TTCCACAATG 
CCTGTCTATG AGTTGAAAGG ACTGAAGACC AACTTGGATA TTCAGCAGTA TAACTACATA 
AACCAAATGT GCTACGAAAA GGCTCTGCAT TGGTATGCAA AGTACTTCCC TTATCTGGTT 
CTCATACATA CCCTAATTTT CATAGTGTGC AGCAATTTTT GGTTCAAGTT CCCTGGCTCC 
AGCTCTAAAA TTGAGCACTT TATATCAATC CTGGGCAAAT GTTTTGACTC ACCATGGACT 
ACGAGAGCAC TGTCTGAAGT TTCTGGAGAG AATCCGGAGG AGAAAGACAA CAAGAAGAAC 
AGTGCCAGCA GGTTAAACCT TGAAACTCCA ATTGGAGAGG GCAACCTGGA GAAGACTCAG 
TCTTTAAGAT CAATTCCTGA AAAGATTGTT GTTGACAAGC CAGCACCAAG TGTCCTTGAC 
AAAAAGGAAG GAGAGCAAGC CAAGGCTTTG TTTGAAAAGG TCAAAAAATT TCGCCTACAT 
GTGGAAGAGG GTGATATACT ATATATGATG TATGTTCGCC AGACTGTCGT AAAAGTGCTG 
AAGTTTATCC TTATAATTGC GTACAACAGC GTTCTGGTGT CAAAGGTTAG ATTCAGTGTT 
ACTTGTACCG AGAACATGCT GGACATGACA GGTTACCGGT ACTTCTGTTG CAATCATACT 
ATGGCCCACT TGTTCTCTAA GCTTTCCTAC TGTTACTTGT GTTTTGTTGG TGTTTATGGA 
CTCACGTGCC TTTATACATC ATACTGGTTG TTCTACATTT CCCTCAAGGA ATACTCCTTT 
GAATATGTTA GGCAAGAGAC TGGAATTGAT GACATCCCTG ATGTAAAAAA TGACTTTGCT 
TTCATGTTGC ACATGATTGA TCAGTACGAT CCCCTGTATT CCAAGAGATT TGCAGTGTTT 
TTGTCTGAGG TGAGCGAAAA CAAGTTGAAG CAGCTCAACC TTAACCATGA GTGGACAGCC 
GACAAGCTTC GGCAGAAGCT GCAGACTAAC AGCAATAACA GGCTAGAACT TCAACTCTTC 
ATGCTGTATG GTCTCCCTGA TACCATCTTT GAGGTGACTG AGCTCCAGTC GTTGAAGCTT 
GAGATCATTA ATAATGTGAC CATACCAGCA GCCATTGCCC AACTGGAAGA TCTCCAGGAG 
CTTTCGCTTT ACCAGTGCTC ACTCAAGATC CACAGTGCAG CCACCTCATT CCTCAAGGAG 
AACTTGAAGG TTTTGCGTGT AAAGTTTGAT GACAGCCGTG AACTCCCACA GTGGTTGTAT 
GTTTTGCGGA ATTTGGAAGA GCTTCATCTG ATTGGCTCAT TAGGTTCAGA CGCAGCAAAG 
AACGTAACCC TAGACTCTCT ACGAGAGCTC AAAGCGTTGA AGACCCTGAC ACTCAAGAGC 
AACTTCACCA AAATCCCACA GTCCATCGTA GATGTGGCCA GCCATCTACA ACGCCTCAGT 
ATTTGCAATG ATGGCACCAA ACTGGTCATG CTTAACAACC TGAAAAAGAT GGGCAATCTT 
ACGGAACTTG AGTTGGTTCA CTGCGACCTG GAACGTATAC CCCATGCTAT TTTTAGCCTG 
ACTAACCTGC AGATGTTGGA TCTGAAAGAA AATAATCTAC GCTCCATTGA AGAGATCCTT 
AGCTTCCAGC ATCTCCGCAA GTTGACCTGT CTGAAGCTTT GGCACAATGG CATCGCTTTT 
ATACCTGAAC ACATCAAAAA ACTTGGCAGC TTGGAGCGCC TCTACCTTAG CCATAATAAG 
ATTGAGATCT TGCCTTCACA CTTGTTCCTC TGCAACAAAC TGCGCTACCT CGACGTTTCC 
AATAACGACA TCCGTTTTAT TCCACCAGAG ATTGGCGTCC TTCAAAGCCT TCAGTACTTC 
TCTGTTAGCT GTAACAAAAT CGAGAATATT CCTGATGAAC TTTTCTTCTG CAAGAAGCTG 
AAGACGCTGA AGCTAGGCAG AAACATGCTG TCTGTCCTCT CTCCAAAGAT TTCTTTCCTA 
AGCGTACTGA CTCATTTGGA GTTAAAGGGT AATCACTTTG AGATCTTACC AGCTGAACTT 
GGGGCTTGCT GTGCATTAAA ACGCAGTGGA CTTGCGGTAG AAGATGCACT GTTTGAGACG 
CTGCCTTCAG ACATCAGGGA ACAAATGCAA GAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001313473.1
CDS	116..2494
Translation	MIPVTEFRQFTEQQPAFRVLKPWWDVFTDYLSVVMLMIGVFGCTLQVMQDKIICLPQRTFSTNQTELMCPPPSSNQVSTMPVYELKGLKTNLDIQQYNYINQMCYEKALHWYAKYFPYLVLIHTLIFIVCSNFWFKFPGSSSKIEHFISILGKCFDSPWTTRALSEVSGENPEEKDNKKNSASRLNLETPIGEGNLEKTQSLRSIPEKIVVDKPAPSVLDKKEGEQAKALFEKVKKFRLHVEEGDILYMMYVRQTVVKVLKFILIIAYNSVLVSKVRFSVTCTENMLDMTGYRYFCCNHTMAHLFSKLSYCYLCFVGVYGLTCLYTSYWLFYISLKEYSFEYVRQETGIDDIPDVKNDFAFMLHMIDQYDPLYSKRFAVFLSEVSENKLKQLNLNHEWTADKLRQKLQTNSNNRLELQLFMLYGLPDTIFEVTELQSLKLEIINNVTIPAAIAQLEDLQELSLYQCSLKIHSAATSFLKENLKVLRVKFDDSRELPQWLYVLRNLEELHLIGSLGSDAAKNVTLDSLRELKALKTLTLKSNFTKIPQSIVDVASHLQRLSICNDGTKLVMLNNLKKMGNLTELELVHCDLERIPHAIFSLTNLQMLDLKENNLRSIEEILSFQHLRKLTCLKLWHNGIAFIPEHIKKLGSLERLYLSHNKIEILPSHLFLCNKLRYLDVSNNDIRFIPPEIGVLQSLQYFSVSCNKIENIPDELFFCKKLKTLKLGRNMLSVLSPKISFLSVLTHLELKGNHFEILPAELGACCALKRSGLAVEDALFETLPSDIREQMQEE

Target ORF information:

RefSeq Version	NM_001326544.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio leucine rich repeat containing 8 VRAC subunit C (lrrc8c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001326544.1

ORF Insert Sequence:

ATGATTCCAG TGACTGAATT CCGGCAGTTC ACGGAACAGC AGCCAGCGTT CCGGGTTCTG 
AAGCCATGGT GGGACGTGTT CACAGACTAC CTCTCTGTGG TCATGCTTAT GATAGGCGTG 
TTTGGATGCA CTCTGCAGGT GATGCAGGAC AAAATCATAT GCCTTCCTCA AAGGACATTC 
TCTACAAACC AGACAGAGCT GATGTGCCCT CCTCCTTCTT CAAATCAGGT TTCCACAATG 
CCTGTCTATG AGTTGAAAGG ACTGAAGACC AACTTGGATA TTCAGCAGTA TAACTACATA 
AACCAAATGT GCTACGAAAA GGCTCTGCAT TGGTATGCAA AGTACTTCCC TTATCTGGTT 
CTCATACATA CCCTAATTTT CATAGTGTGC AGCAATTTTT GGTTCAAGTT CCCTGGCTCC 
AGCTCTAAAA TTGAGCACTT TATATCAATC CTGGGCAAAT GTTTTGACTC ACCATGGACT 
ACGAGAGCAC TGTCTGAAGT TTCTGGAGAG AATCCGGAGG AGAAAGACAA CAAGAAGAAC 
AGTGCCAGCA GGTTAAACCT TGAAACTCCA ATTGGAGAGG GCAACCTGGA GAAGACTCAG 
TCTTTAAGAT CAATTCCTGA AAAGATTGTT GTTGACAAGC CAGCACCAAG TGTCCTTGAC 
AAAAAGGAAG GAGAGCAAGC CAAGGCTTTG TTTGAAAAGG TCAAAAAATT TCGCCTACAT 
GTGGAAGAGG GTGATATACT ATATATGATG TATGTTCGCC AGACTGTCGT AAAAGTGCTG 
AAGTTTATCC TTATAATTGC GTACAACAGC GTTCTGGTGT CAAAGGTTAG ATTCAGTGTT 
ACTTGTACCG AGAACATGCT GGACATGACA GGTTACCGGT ACTTCTGTTG CAATCATACT 
ATGGCCCACT TGTTCTCTAA GCTTTCCTAC TGTTACTTGT GTTTTGTTGG TGTTTATGGA 
CTCACGTGCC TTTATACATC ATACTGGTTG TTCTACATTT CCCTCAAGGA ATACTCCTTT 
GAATATGTTA GGCAAGAGAC TGGAATTGAT GACATCCCTG ATGTAAAAAA TGACTTTGCT 
TTCATGTTGC ACATGATTGA TCAGTACGAT CCCCTGTATT CCAAGAGATT TGCAGTGTTT 
TTGTCTGAGG TGAGCGAAAA CAAGTTGAAG CAGCTCAACC TTAACCATGA GTGGACAGCC 
GACAAGCTTC GGCAGAAGCT GCAGACTAAC AGCAATAACA GGCTAGAACT TCAACTCTTC 
ATGCTGTATG GTCTCCCTGA TACCATCTTT GAGGTGACTG AGCTCCAGTC GTTGAAGCTT 
GAGATCATTA ATAATGTGAC CATACCAGCA GCCATTGCCC AACTGGAAGA TCTCCAGGAG 
CTTTCGCTTT ACCAGTGCTC ACTCAAGATC CACAGTGCAG CCACCTCATT CCTCAAGGAG 
AACTTGAAGG TTTTGCGTGT AAAGTTTGAT GACAGCCGTG AACTCCCACA GTGGTTGTAT 
GTTTTGCGGA ATTTGGAAGA GCTTCATCTG ATTGGCTCAT TAGGTTCAGA CGCAGCAAAG 
AACGTAACCC TAGACTCTCT ACGAGAGCTC AAAGCGTTGA AGACCCTGAC ACTCAAGAGC 
AACTTCACCA AAATCCCACA GTCCATCGTA GATGTGGCCA GCCATCTACA ACGCCTCAGT 
ATTTGCAATG ATGGCACCAA ACTGGTCATG CTTAACAACC TGAAAAAGAT GGGCAATCTT 
ACGGAACTTG AGTTGGTTCA CTGCGACCTG GAACGTATAC CCCATGCTAT TTTTAGCCTG 
ACTAACCTGC AGATGTTGGA TCTGAAAGAA AATAATCTAC GCTCCATTGA AGAGATCCTT 
AGCTTCCAGC ATCTCCGCAA GTTGACCTGT CTGAAGCTTT GGCACAATGG CATCGCTTTT 
ATACCTGAAC ACATCAAAAA ACTTGGCAGC TTGGAGCGCC TCTACCTTAG CCATAATAAG 
ATTGAGATCT TGCCTTCACA CTTGTTCCTC TGCAACAAAC TGCGCTACCT CGACGTTTCC 
AATAACGACA TCCGTTTTAT TCCACCAGAG ATTGGCGTCC TTCAAAGCCT TCAGTACTTC 
TCTGTTAGCT GTAACAAAAT CGAGAATATT CCTGATGAAC TTTTCTTCTG CAAGAAGCTG 
AAGACGCTGA AGCTAGGCAG AAACATGCTG TCTGTCCTCT CTCCAAAGAT TTCTTTCCTA 
AGCGTACTGA CTCATTTGGA GTTAAAGGGT AATCACTTTG AGATCTTACC AGCTGAACTT 
GGGGCTTGCT GTGCATTAAA ACGCAGTGGA CTTGCGGTAG AAGATGCACT GTTTGAGACG 
CTGCCTTCAG ACATCAGGGA ACAAATGCAA GAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Briefings in bioinformatics12(5)449-62(2011 Sep)
Gaudet P,Livstone MS,Lewis SE,Thomas PD