myoc cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	myoc
Entrez Gene ID	548602
Full Name	myocilin
Synonyms	zgc:136645
General protein information	Preferred Names myocilin Names myocilin
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001015062.2	NP_001015062.1	myocilin precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	MYOC	NP_000252.1
	MYOC	XP_001099905.1
Danio rerio (zebrafish)	myoc	NP_001015062.1
Mus musculus (house mouse)	Myoc	NP_034995.3
Gallus gallus (chicken)	MYOC	XP_422235.4
Xenopus tropicalis (tropical clawed frog)	myoc	XP_002934195.2
Pan troglodytes (chimpanzee)	MYOC	XP_513995.2
Canis lupus familiaris (dog)	MYOC	NP_001041495.2
Bos taurus (cattle)	MYOC	NP_776543.2
Rattus norvegicus (Norway rat)	Myoc	NP_110492.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis.
Biswas G, Kinoshita S, Kono T, Hikima J, Sakai M
Marine genomics2225-36(2015 Aug)

Evolution and genomic organization of muscle microRNAs in fish genomes.
Nachtigall PG, Dias MC, Pinhal D
BMC evolutionary biology14196(2014 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following myoc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the myoc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa33510	NM_001015062.2 Latest version!	Danio rerio myocilin (myoc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

myoc ( NM_001015062.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001015062.1 Danio rerio myocilin (myoc), mRNA.

Price & Availability↑

CloneID	ODa33510
Clone ID Related Accession (Same CDS sequence)	NM_001015062.2
Accession Version	NM_001015062.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	myocilin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC115210.1. On Apr 23, 2006 this sequence version replaced NM_001015062.1. ##Evidence-Data-START## Transcript exon combination :: BC115210.1, AY551079.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTGGTTTT TAGCAGTGTT GTGGATTTCT TCCCTGCTGA TGGGATCCCA GGTTCAGAGC 
AGTGCTAACC TTCGTCGAGC AAATGCTGGG AATGGTCGCT GTCAGTACAC CTTTATGGTG 
GACAGCCCTA CTGAGGCCAG CTGTCCATCA CCAGGTTCAA CTCCTGAGAT GGAGGCTCTG 
ATGTCTCGCC TGGGGCTGCT AGAGGCACTG GTTGCTCGTC TCGTAGGAGG GGAAGCCATG 
CCAGAATCAT CACAGAGCTC GGGATCTGGC CTTCAGGACT CTTACAACCA GGTGATGGGG 
GAGAACGCGC AGCTCAAGAG AGAAAAGCAG AGACTAGACA GACAAGTTCA GGACCTGCAG 
CAGAGGATGG AAGAGCTCCG CCAAGAGGCT GAGAGGCTGA GGAGCAGACC CTGCATGCAG 
CAAACTTCTT CCAGAGTGCC GCAAAAAGAC AACAGCTTCA GACCGGGATC AGGGCATGTA 
CCCTCCAACT TGGCATCCAG ACCTGGGAAT CCACAAGAAG ACAAAAGTAG TTTAAGAGAC 
CCCGCATGGC AGTACTCAAA TCCCGGATAC CAAGAGTTGA CGGCTGTGGT CACCGAGGTG 
ACTGCCCCAA ATCAGGACGG TCCAGCAGAT ATCTCAGGCT GTGGTGATCT GGTGTGGGTT 
GAAAATCCTG AGGTGCATCG TAAAGCTGAT AGTATTGCTG GTAAATATGG TGTGTGGATG 
CAAGATCCAG AAGCCAAGGA ACCTTATGGT CCAGACATGG TATGGCGTAT TGATTCTGTC 
GGTTCTGAAG TGCGTCAACT CTTCGGATAT GAAAACATGG ACCAGCTGAC ACGTGGCTTT 
CCCACCAAGG TTCTACTCCT GCCAGAATCT GTAGAGAGCA CAGGTGCTAC CATGTATAAA 
GGCTCCTTAT ACTACCAGCG GAGGCTCAGC CGCACCCTAA TAAGATACGA CCTACATGCT 
GAGAGCATTG CTGCTCGTCG TGATCTACCC CATGCTGGTT TCCATGGTCA GTTCCCCTAC 
TCATGGGGTG GCTACACAGA CATTGACTTG GCAATAGATG AAAATGGCTT ATGGGCTATA 
TACAGCACAA ATAAAGCCAA GGGTGCTATC GTGATCTCCC AGCTGGACCC TCACAACCTT 
GAGGTGAAGG GTACCTGGGA AACAAAAATC CGCAAGACAT CTGTGGCTAA CGCTTTTATG 
ATCTGTGGCA AGCTCTACAC AGTTGCTAGT TACACCTCAC CAAACACCAC GGTTAATTAC 
ATGTTTGACA CTGCAACCAG CCAGGGTAAA GCAATATCAG TGCCCTTCAA AAACCGTTAT 
CGCTACAACA GCATGGTAGA CTACAACTCC GCAAAAAGAA AGCTGTATGC TTGGGATAAT 
TATTACATGG TGTCTTACAG TGTGAGACTT GGCAAGCAGG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001015062.1
CDS	303..1727
Translation	MWFLAVLWISSLLMGSQVQSSANLRRANAGNGRCQYTFMVDSPTEASCPSPGSTPEMEALMSRLGLLEALVARLVGGEAMPESSQSSGSGLQDSYNQVMGENAQLKREKQRLDRQVQDLQQRMEELRQEAERLRSRPCMQQTSSRVPQKDNSFRPGSGHVPSNLASRPGNPQEDKSSLRDPAWQYSNPGYQELTAVVTEVTAPNQDGPADISGCGDLVWVENPEVHRKADSIAGKYGVWMQDPEAKEPYGPDMVWRIDSVGSEVRQLFGYENMDQLTRGFPTKVLLLPESVESTGATMYKGSLYYQRRLSRTLIRYDLHAESIAARRDLPHAGFHGQFPYSWGGYTDIDLAIDENGLWAIYSTNKAKGAIVISQLDPHNLEVKGTWETKIRKTSVANAFMICGKLYTVASYTSPNTTVNYMFDTATSQGKAISVPFKNRYRYNSMVDYNSAKRKLYAWDNYYMVSYSVRLGKQE

Target ORF information:

RefSeq Version	NM_001015062.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio myocilin (myoc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001015062.2

ORF Insert Sequence:

ATGTGGTTTT TAGCAGTGTT GTGGATTTCT TCCCTGCTGA TGGGATCCCA GGTTCAGAGC 
AGTGCTAACC TTCGTCGAGC AAATGCTGGG AATGGTCGCT GTCAGTACAC CTTTATGGTG 
GACAGCCCTA CTGAGGCCAG CTGTCCATCA CCAGGTTCAA CTCCTGAGAT GGAGGCTCTG 
ATGTCTCGCC TGGGGCTGCT AGAGGCACTG GTTGCTCGTC TCGTAGGAGG GGAAGCCATG 
CCAGAATCAT CACAGAGCTC GGGATCTGGC CTTCAGGACT CTTACAACCA GGTGATGGGG 
GAGAACGCGC AGCTCAAGAG AGAAAAGCAG AGACTAGACA GACAAGTTCA GGACCTGCAG 
CAGAGGATGG AAGAGCTCCG CCAAGAGGCT GAGAGGCTGA GGAGCAGACC CTGCATGCAG 
CAAACTTCTT CCAGAGTGCC GCAAAAAGAC AACAGCTTCA GACCGGGATC AGGGCATGTA 
CCCTCCAACT TGGCATCCAG ACCTGGGAAT CCACAAGAAG ACAAAAGTAG TTTAAGAGAC 
CCCGCATGGC AGTACTCAAA TCCCGGATAC CAAGAGTTGA CGGCTGTGGT CACCGAGGTG 
ACTGCCCCAA ATCAGGACGG TCCAGCAGAT ATCTCAGGCT GTGGTGATCT GGTGTGGGTT 
GAAAATCCTG AGGTGCATCG TAAAGCTGAT AGTATTGCTG GTAAATATGG TGTGTGGATG 
CAAGATCCAG AAGCCAAGGA ACCTTATGGT CCAGACATGG TATGGCGTAT TGATTCTGTC 
GGTTCTGAAG TGCGTCAACT CTTCGGATAT GAAAACATGG ACCAGCTGAC ACGTGGCTTT 
CCCACCAAGG TTCTACTCCT GCCAGAATCT GTAGAGAGCA CAGGTGCTAC CATGTATAAA 
GGCTCCTTAT ACTACCAGCG GAGGCTCAGC CGCACCCTAA TAAGATACGA CCTACATGCT 
GAGAGCATTG CTGCTCGTCG TGATCTACCC CATGCTGGTT TCCATGGTCA GTTCCCCTAC 
TCATGGGGTG GCTACACAGA CATTGACTTG GCAATAGATG AAAATGGCTT ATGGGCTATA 
TACAGCACAA ATAAAGCCAA GGGTGCTATC GTGATCTCCC AGCTGGACCC TCACAACCTT 
GAGGTGAAGG GTACCTGGGA AACAAAAATC CGCAAGACAT CTGTGGCTAA CGCTTTTATG 
ATCTGTGGCA AGCTCTACAC AGTTGCTAGT TACACCTCAC CAAACACCAC GGTTAATTAC 
ATGTTTGACA CTGCAACCAG CCAGGGTAAA GCAATATCAG TGCCCTTCAA AAACCGTTAT 
CGCTACAACA GCATGGTAGA CTACAACTCC GCAAAAAGAA AGCTGTATGC TTGGGATAAT 
TATTACATGG TGTCTTACAG TGTGAGACTT GGCAAGCAGG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis.
Marine genomics2225-36(2015 Aug)
Biswas G,Kinoshita S,Kono T,Hikima J,Sakai M

Evolution and genomic organization of muscle microRNAs in fish genomes.
BMC evolutionary biology14196(2014 Sep)
Nachtigall PG,Dias MC,Pinhal D