mtrex cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	mtrex
Entrez Gene ID	406795
Full Name	Mtr4 exosome RNA helicase
Synonyms	skiv2l2,wu:fd11a05,zgc:63838
General protein information	Preferred Names Mtr4 exosome RNA helicase Names superkiller viralicidic activity 2-like 2 julie
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_214768.1	NP_999933.1	superkiller viralicidic activity 2-like 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SKIV2L2	XP_849676.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009600	XP_318627.4
Homo sapiens (human)	SKIV2L2	NP_056175.3
Rattus norvegicus (Norway rat)	Skiv2l2	NP_001029265.1
Caenorhabditis elegans (roundworm)	mtr-4	NP_501757.1
Kluyveromyces lactis	KLLA0F01364g	XP_455141.1
Neurospora crassa	NCU03363	XP_956298.1
Pan troglodytes (chimpanzee)	SKIV2L2	XP_001145794.1
Schizosaccharomyces pombe (fission yeast)	mtr4	NP_593302.1
Arabidopsis thaliana (thale cress)	AT1G59760	NP_176185.1
Xenopus tropicalis (tropical clawed frog)	skiv2l2	XP_002941157.1
Saccharomyces cerevisiae (baker's yeast)	MTR4	NP_012485.1
	LOC706419	XP_002808474.1
Mus musculus (house mouse)	Skiv2l2	NP_082427.1
Gallus gallus (chicken)	SKIV2L2	NP_001012962.1
Danio rerio (zebrafish)	skiv2l2	NP_999933.1
Drosophila melanogaster (fruit fly)	l(2)35Df	NP_524929.1
Eremothecium gossypii	AGOS_AEL181C	NP_984680.2
Magnaporthe oryzae (rice blast fungus)	MGG_03931	XP_003719933.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.
Yang CT, Hindes AE, Hultman KA, Johnson SL
PLoS genetics3(6)e88(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Stage-specific roles in melanocyte regeneration, not only in early stages of the regeneration process, but also in late stages of differentiation of the regenerating melanocyte.
Title: Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.

The following mtrex gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mtrex cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa33801	NM_214768.1 Latest version!	Danio rerio Mtr4 exosome RNA helicase (mtrex), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

mtrex ( NM_214768.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_999933.1 Danio rerio Mtr4 exosome RNA helicase (mtrex), mRNA.

Price & Availability↑

CloneID	ODa33801
Clone ID Related Accession (Same CDS sequence)	NM_214768.1
Accession Version	NM_214768.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3105bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	superkiller viralicidic activity 2-like 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC061456.1. On Jul 6, 2005 this sequence version replaced XM_692456.1. ##Evidence-Data-START## Transcript exon combination :: BC061456.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGACG CCTTTGGAGA CGATTTGTTC AGCGTGTTTG ATGAAGAACA GGCCGGTTCC 
AGCAAAAAGG CCGCTCCAAA GTCCGCAGCT AATGCAGGGA AAACGCCTGA TAAAGCTGGC 
AAACCACAGG GAGATTCAGC ATCTTTGCGC AAAAGAGATG CTGATGATGA TGGTCCTGAT 
GAGATGCTGC TGGGGAAAAG GCAAAAGCTG GAAACGGTGT CAGCGGAGGA GATCAATCTG 
TCAGAGCTTA TGCCGAAAGT GAAATCAGAG CAGGTGGAGA CAGTGGAGGG CTGCACTCAT 
GAGGTGGTTC TTCCTGCCAA TGAGGAATAC ACTCCGCTGA AACCACGTGT TGGAAAAGCT 
GCCAAGGAGT ATCCCTTCAT ACTCGACCCT TTTCAGCGTG AGGCCATCCT GTGCATCGAT 
AACAACCAGT CTGTGCTTGT GTCGGCCCAC ACGTCAGCAG GAAAGACCGT GTGTGCCGAG 
TATGCCATTG CTCTGGCACT CAGAGAAAAG CAGCGTGTCA TCTTCACCAG CCCCATCAAA 
GCTCTGAGCA ACCAGAAGTA CAGAGAGATG TACGAGGAGT TTCAGGACGT GGGGCTGATG 
ACCGGTGATG TCACTATTAA CCCCACTGCT TCCTGTCTGG TCATGACCAC AGAGATTTTG 
AGGAGCATGC TGTACAGGGG GTCAGAGGTC ATGAGGGAGG TGGCATGGGT CATCTTTGAT 
GAGATCCATT ACATGAGAGA CTCAGAACGT GGCGTGGTCT GGGAAGAGAC CATCATCCTG 
CTACCAGATA ATGTACACCA TGTTTTCCTT TCTGCCACCG TTCCTAATGC TAGACAGTTC 
GCAGAGTGGA TTTGTCACCT CCACAAACAG CCTTGTCACG TGGTGTACAC AGACTACCGT 
CCCACTCCAT TGCAGCACTA CATCTTTCCA GCAGGGGGCG ATGGACTCCA TCTTGTCGTG 
GATGAGAACG GAGAGTTCAG AGAAGACAAT TTTAACACCG CAATGCAGGT CCTTAGGGAT 
GCGGGGGATA CAGGAGGCAA CACTGGGGCC AAATGGGACC CCAAAGGCAG AAAAGGTGGA 
ACAAAAGGTC CATCTAACGT CTTCAAGATC GTGAAGATGA TCATGGAGAG GAACTTCCAG 
CCTGTGATCA TCTTCAGCTT CAGTAAGAAA GAGTGTGAGG CCTATGCTCT GCAAGTCTCC 
AAACTGGATT TCAACACAGA CGAAGAGAAA AAACTGGTAG AAGAAGTGTT CAACAATGCC 
ACAGACTGCC TCTCTGATGA GGACAAAAAA CTGCCACAGG TGGAGCATGT GTTGCCGCTG 
CTCAAGAGAG GAATAGGCAT TCATCATGGT GGCCTCTTGC CCATCCTGAA GGAGACCATT 
GAGATCCTCT TTTCTGAGGG GCTGCTGAAG GCCTTATTCG CTACAGAAAC ATTTGCCATG 
GGGATCAACA TGCCTGCGCG AACCGTTCTC TTCACCAGTG CTCGAAAATT CGACGGCAAA 
GACTTCCGCT GGATCTCCTC TGGAGAGTAT ATCCAGATGT CAGGACGTGC CGGCAGAAGA 
GGAATGGACG AAAGGGGAAT CGTCATATTC ATGGTTGATG AGAAGATGAG CCCTGCAGTC 
GGCAAACAAT TACTGAAGGG TTCGGCAGAT CCTCTGAACA GTGCGTTTCA CCTGACCTAC 
AACATGGTGC TCAATCTGCT GCGTGTGGAG GAGATCAACC CAGAGTACAT GCTGGAGAAA 
TCCTTTTACC AGTTCCAGCA CTACAGAGCC GTGCCTGGCG TTGTGGATAG GATGAAAAAG 
CTGGAGGAGG AATATAACGC CATACGAATC CCCAAGGAGG AGAGCGTGGT GACCTACTAC 
AAGATTCGCC AACAGCTGGC CAAATTGGGC AAAGAAATCG AGGAGTTTAT TCACAAACCC 
AGATACTGCC TGCCCTTCTT ACAGCCAGGC AGACTGGTCA AGGTAAAAAA AGAAGATCTG 
GATTTTGGTT GGGGTGTAGT CGTCAATTTC CAAAAGAAGT CAAATGTCAA GGCTGGCGGT 
GACCTTGACC CACTGTTTGT GGTGGAAGTT CTGGTTCACT GCAGTAAAGA CAGCGTGAAG 
AACGCCGCCA CGGAGTCAGC CAGACCCGCT GGCCCTGCAG AGAAGGGAGA GATGCAGGTC 
GTTCCTGTGA TTCTTCATCT CATCACCTCT ATTAGTTCTG TGCGCCTCTA CATCCCTAAA 
GACCTGCGGC CCTATGATAA CCGGCAGAGC ATGCTCAAAT CCATACAGGA GGTGCAGAAA 
CGTTTCCCAG ATGGGATACC GTTGCTGGAT CCCATAGATG ACATGGGAAT CAAGGATCCC 
GCCCTGAAGA AGGTCATCCA GAAGGTGGAG GCATTCGAGC ACAGGATGTA CACGCACCCG 
CTGCACAGCG ACCCCAACCT GGAGGCCGTT TACAAACTCT GTGAGAAGAA AGCGCTGATT 
GCGGGTGATA TTAAAGCAGC AAAGCGAGAG CTAAAGAAAG CCCGCACCGT GTTGCAGATG 
GATGAGTTGA AGTGCAGAAA GCGTGTGCTG CGCCGACTGG GATTCGCTAC TTCCTCTGAT 
GTCATCGAGA TGAAGGGCCG TGTGGCATGC GAGACCAGCA GTGGAGATGA GCTGCTGCTG 
ACAGAGATGA TGTTTAACGG CTTGTTCAAT GACCTGACGG CGGAGCAGGC CACCGCTCTC 
CTCAGCTGCT TCGTCTTCCA GGAAAACGCC AACGAGATGC CCAAACTGAC AGAGCAGCTG 
GGCGGTCCAC TGAGACAGAT GCAGGAATGT GCCAAGAGAA TTGCTAAAGT GTCTGCAGAG 
GCCAAGCTGG AAGTGGACGA GGACAGTTAC CTGAACCAGT TCCGTCCGCA CCTAATGGAT 
GTGGTCTACA CCTGGGCCAA TGGCTCTTCC TTCTCTCAGA TTTGCAAAAT GACAGACGTG 
TTTGAAGGCA GTATTATCCG CTGTATGCGC AGACTGGAGG AGCTCTTAAG GCAGATGTGC 
CAGGCAGCTA AGGCTATTGG AAACACAGAG TTGGAGAATA AGTTTGCAAC CGGTATAACG 
AAGATTAAGA GGGATATCGT GTTTGCTGCA AGTCTATACC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_999933.1
CDS	24..3128
Translation	MADAFGDDLFSVFDEEQAGSSKKAAPKSAANAGKTPDKAGKPQGDSASLRKRDADDDGPDEMLLGKRQKLETVSAEEINLSELMPKVKSEQVETVEGCTHEVVLPANEEYTPLKPRVGKAAKEYPFILDPFQREAILCIDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHHVFLSATVPNARQFAEWICHLHKQPCHVVYTDYRPTPLQHYIFPAGGDGLHLVVDENGEFREDNFNTAMQVLRDAGDTGGNTGAKWDPKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKECEAYALQVSKLDFNTDEEKKLVEEVFNNATDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVIFMVDEKMSPAVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAVPGVVDRMKKLEEEYNAIRIPKEESVVTYYKIRQQLAKLGKEIEEFIHKPRYCLPFLQPGRLVKVKKEDLDFGWGVVVNFQKKSNVKAGGDLDPLFVVEVLVHCSKDSVKNAATESARPAGPAEKGEMQVVPVILHLITSISSVRLYIPKDLRPYDNRQSMLKSIQEVQKRFPDGIPLLDPIDDMGIKDPALKKVIQKVEAFEHRMYTHPLHSDPNLEAVYKLCEKKALIAGDIKAAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACETSSGDELLLTEMMFNGLFNDLTAEQATALLSCFVFQENANEMPKLTEQLGGPLRQMQECAKRIAKVSAEAKLEVDEDSYLNQFRPHLMDVVYTWANGSSFSQICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFATGITKIKRDIVFAASLYL

Target ORF information:

RefSeq Version	NM_214768.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio Mtr4 exosome RNA helicase (mtrex), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_214768.1

ORF Insert Sequence:

ATGGCGGACG CCTTTGGAGA CGATTTGTTC AGCGTGTTTG ATGAAGAACA GGCCGGTTCC 
AGCAAAAAGG CCGCTCCAAA GTCCGCAGCT AATGCAGGGA AAACGCCTGA TAAAGCTGGC 
AAACCACAGG GAGATTCAGC ATCTTTGCGC AAAAGAGATG CTGATGATGA TGGTCCTGAT 
GAGATGCTGC TGGGGAAAAG GCAAAAGCTG GAAACGGTGT CAGCGGAGGA GATCAATCTG 
TCAGAGCTTA TGCCGAAAGT GAAATCAGAG CAGGTGGAGA CAGTGGAGGG CTGCACTCAT 
GAGGTGGTTC TTCCTGCCAA TGAGGAATAC ACTCCGCTGA AACCACGTGT TGGAAAAGCT 
GCCAAGGAGT ATCCCTTCAT ACTCGACCCT TTTCAGCGTG AGGCCATCCT GTGCATCGAT 
AACAACCAGT CTGTGCTTGT GTCGGCCCAC ACGTCAGCAG GAAAGACCGT GTGTGCCGAG 
TATGCCATTG CTCTGGCACT CAGAGAAAAG CAGCGTGTCA TCTTCACCAG CCCCATCAAA 
GCTCTGAGCA ACCAGAAGTA CAGAGAGATG TACGAGGAGT TTCAGGACGT GGGGCTGATG 
ACCGGTGATG TCACTATTAA CCCCACTGCT TCCTGTCTGG TCATGACCAC AGAGATTTTG 
AGGAGCATGC TGTACAGGGG GTCAGAGGTC ATGAGGGAGG TGGCATGGGT CATCTTTGAT 
GAGATCCATT ACATGAGAGA CTCAGAACGT GGCGTGGTCT GGGAAGAGAC CATCATCCTG 
CTACCAGATA ATGTACACCA TGTTTTCCTT TCTGCCACCG TTCCTAATGC TAGACAGTTC 
GCAGAGTGGA TTTGTCACCT CCACAAACAG CCTTGTCACG TGGTGTACAC AGACTACCGT 
CCCACTCCAT TGCAGCACTA CATCTTTCCA GCAGGGGGCG ATGGACTCCA TCTTGTCGTG 
GATGAGAACG GAGAGTTCAG AGAAGACAAT TTTAACACCG CAATGCAGGT CCTTAGGGAT 
GCGGGGGATA CAGGAGGCAA CACTGGGGCC AAATGGGACC CCAAAGGCAG AAAAGGTGGA 
ACAAAAGGTC CATCTAACGT CTTCAAGATC GTGAAGATGA TCATGGAGAG GAACTTCCAG 
CCTGTGATCA TCTTCAGCTT CAGTAAGAAA GAGTGTGAGG CCTATGCTCT GCAAGTCTCC 
AAACTGGATT TCAACACAGA CGAAGAGAAA AAACTGGTAG AAGAAGTGTT CAACAATGCC 
ACAGACTGCC TCTCTGATGA GGACAAAAAA CTGCCACAGG TGGAGCATGT GTTGCCGCTG 
CTCAAGAGAG GAATAGGCAT TCATCATGGT GGCCTCTTGC CCATCCTGAA GGAGACCATT 
GAGATCCTCT TTTCTGAGGG GCTGCTGAAG GCCTTATTCG CTACAGAAAC ATTTGCCATG 
GGGATCAACA TGCCTGCGCG AACCGTTCTC TTCACCAGTG CTCGAAAATT CGACGGCAAA 
GACTTCCGCT GGATCTCCTC TGGAGAGTAT ATCCAGATGT CAGGACGTGC CGGCAGAAGA 
GGAATGGACG AAAGGGGAAT CGTCATATTC ATGGTTGATG AGAAGATGAG CCCTGCAGTC 
GGCAAACAAT TACTGAAGGG TTCGGCAGAT CCTCTGAACA GTGCGTTTCA CCTGACCTAC 
AACATGGTGC TCAATCTGCT GCGTGTGGAG GAGATCAACC CAGAGTACAT GCTGGAGAAA 
TCCTTTTACC AGTTCCAGCA CTACAGAGCC GTGCCTGGCG TTGTGGATAG GATGAAAAAG 
CTGGAGGAGG AATATAACGC CATACGAATC CCCAAGGAGG AGAGCGTGGT GACCTACTAC 
AAGATTCGCC AACAGCTGGC CAAATTGGGC AAAGAAATCG AGGAGTTTAT TCACAAACCC 
AGATACTGCC TGCCCTTCTT ACAGCCAGGC AGACTGGTCA AGGTAAAAAA AGAAGATCTG 
GATTTTGGTT GGGGTGTAGT CGTCAATTTC CAAAAGAAGT CAAATGTCAA GGCTGGCGGT 
GACCTTGACC CACTGTTTGT GGTGGAAGTT CTGGTTCACT GCAGTAAAGA CAGCGTGAAG 
AACGCCGCCA CGGAGTCAGC CAGACCCGCT GGCCCTGCAG AGAAGGGAGA GATGCAGGTC 
GTTCCTGTGA TTCTTCATCT CATCACCTCT ATTAGTTCTG TGCGCCTCTA CATCCCTAAA 
GACCTGCGGC CCTATGATAA CCGGCAGAGC ATGCTCAAAT CCATACAGGA GGTGCAGAAA 
CGTTTCCCAG ATGGGATACC GTTGCTGGAT CCCATAGATG ACATGGGAAT CAAGGATCCC 
GCCCTGAAGA AGGTCATCCA GAAGGTGGAG GCATTCGAGC ACAGGATGTA CACGCACCCG 
CTGCACAGCG ACCCCAACCT GGAGGCCGTT TACAAACTCT GTGAGAAGAA AGCGCTGATT 
GCGGGTGATA TTAAAGCAGC AAAGCGAGAG CTAAAGAAAG CCCGCACCGT GTTGCAGATG 
GATGAGTTGA AGTGCAGAAA GCGTGTGCTG CGCCGACTGG GATTCGCTAC TTCCTCTGAT 
GTCATCGAGA TGAAGGGCCG TGTGGCATGC GAGACCAGCA GTGGAGATGA GCTGCTGCTG 
ACAGAGATGA TGTTTAACGG CTTGTTCAAT GACCTGACGG CGGAGCAGGC CACCGCTCTC 
CTCAGCTGCT TCGTCTTCCA GGAAAACGCC AACGAGATGC CCAAACTGAC AGAGCAGCTG 
GGCGGTCCAC TGAGACAGAT GCAGGAATGT GCCAAGAGAA TTGCTAAAGT GTCTGCAGAG 
GCCAAGCTGG AAGTGGACGA GGACAGTTAC CTGAACCAGT TCCGTCCGCA CCTAATGGAT 
GTGGTCTACA CCTGGGCCAA TGGCTCTTCC TTCTCTCAGA TTTGCAAAAT GACAGACGTG 
TTTGAAGGCA GTATTATCCG CTGTATGCGC AGACTGGAGG AGCTCTTAAG GCAGATGTGC 
CAGGCAGCTA AGGCTATTGG AAACACAGAG TTGGAGAATA AGTTTGCAAC CGGTATAACG 
AAGATTAAGA GGGATATCGT GTTTGCTGCA AGTCTATACC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.
PLoS genetics3(6)e88(2007 Jun)
Yang CT,Hindes AE,Hultman KA,Johnson SL