dpydb cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	dpydb
Entrez Gene ID	405829
Full Name	dihydropyrimidine dehydrogenase b
Synonyms	dpyd,zgc:77205
General protein information	Preferred Names dihydropyrimidine dehydrogenase b Names dihydropyrimidine dehydrogenase [NADP(+)] DHPDHase DPD dihydrothymine dehydrogenase dihydrouracil dehydrogenase
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_212893.1	NP_998058.1	dihydropyrimidine dehydrogenase [NADP(+)]

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DPYD	XP_513583.3
Gallus gallus (chicken)	DPYD	XP_426639.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001021	XP_003437170.1
Xenopus tropicalis (tropical clawed frog)	dpyd	XP_002933845.2
Homo sapiens (human)	DPYD	NP_000101.2
Canis lupus familiaris (dog)	DPYD	XP_005621932.1
Mus musculus (house mouse)	Dpyd	NP_740748.1
Danio rerio (zebrafish)	dpydb	NP_998058.1
Drosophila melanogaster (fruit fly)	su(r)	NP_572538.1
Caenorhabditis elegans (roundworm)	dpyd-1	NP_508927.2
	DPYD	XP_001106007.1
Bos taurus (cattle)	DPYD	NP_776466.1
Rattus norvegicus (Norway rat)	Dpyd	NP_112289.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Integrative view of ?2,3-sialyltransferases (ST3Gal) molecular and functional evolution in deuterostomes: significance of lineage-specific losses.
Petit D, Teppa E, Mir AM, Vicogne D, Thisse C, Thisse B, Filloux C, Harduin-Lepers A
Molecular biology and evolution32(4)906-27(2015 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following dpydb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dpydb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37500	NM_212893.1 Latest version!	Danio rerio dihydropyrimidine dehydrogenase b (dpydb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

dpydb ( NM_212893.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_998058.1 Danio rerio dihydropyrimidine dehydrogenase b (dpydb), mRNA.

Price & Availability↑

CloneID	ODa37500
Clone ID Related Accession (Same CDS sequence)	NM_212893.1
Accession Version	NM_212893.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3069bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Danio rerio(zebrafish)
Product	dihydropyrimidine dehydrogenase [NADP(+)]
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC066602.1. ##Evidence-Data-START## Transcript exon combination :: BC066602.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCTACAA TGCTGAGCAA AGAGTTGCAG GATATTGAGA GTATCCTGGC CTTGAACCCG 
AGGGTGAAGA GCCATGCAAA TGTCCATTCC ACTGCCTCAA AGAAGAATGA GAAGAAGCAC 
TGGAAGAGAA ACCCTGAGAG GAGCTGTGAT TCCTGTGTGA ATTTGGAGAA CAACTTTGAT 
GACATCAAGC ACACGACTCT GAGTGAGCGT GGGGCACTTC GGGAGGCGCT GAGATGCCTG 
AAATGCGCAG ACGCTCCATG CCAGAAAAGC TGCCCCACCA ATTTGGATAT CAAATCTTTC 
ATCACCAGCA TTTCCAACAA GAACTACTAC GGTGCTGCTA AAGCAATCCT GTCCGATAAC 
CCACTGGGTC TGACCTGTGG CATGGTGTGT CCCACCTCTG ATCTGTGCGT TGGGGGCTGT 
AACCTCTACG CCTCTGAGGA AGGGCCTATC AATATTGGTG GGCTTCAGCA GTTCGCTACT 
GAGGTGTTCA GTAAGATGGG CATCCCTCAG ATCAGAAATC CAGAGCTTCC CACGGCGGAC 
AACATGCCGA AGAGTTTCCA CACAAGGATC GCTCTCATTG GCTGCGGCCC TGCCAGCATC 
AGCTGCGCCT CCTTCCTGGC CCGGCTAGGA TATGACAACA TCACCATCTT CGAGAAGCAG 
AAATACATTG GTGGCTTGAG CACTTCAGAA ATCCCTCAGT TCCGGTTGCC CTACGAGGTG 
GTGCAGTTTG AGATTGATCT GATGAAGGAT CTTGGCGTAA AGGTTGTTCT TGAGAAGGGA 
CTGGGGCAGA ATGGCTTGAC TCTGACCTCG CTGAAGGAGG AGGGCTATCA AGTGGTCTAC 
ATTGGCATTG GTCTTCCACA AGCAAACAGG GACAAGATTT TCGAGGGCTT GACCACGGAA 
CAGGGATTCT ACACATCAAA GGATTTCCTT CCTTTGGTTG CAAAAGCCAG TAAAATAGGC 
ATGTGTAATT GCCGCTCACA GCTGCCAAAG CTGCATGGGA ATGTGATCGT CCTGGGTGCA 
GGAGACACAG CGTTCGACTG CGCCACCTCT GCTCTCCGCT GTGGAGCTCG ACGAGTCTTT 
GTGGTCTTTA GAAAGGGCTT CACCAACATT CGCGCTGTTC CAGAAGAGAT GGAGGCAGCC 
AAAGAGGAAA AGTGTGAATT CCTGCCCTTC TTGTCACCTC ATGAGGTAAT AAAGAAAAAT 
GGACGTGTCT CAGGCCTGCG CTTCTGCCGC ACAGAGCAGC AGGATGATGG CACCTGGATT 
GTGGACGAGG AGCAAATTGT CCACCTGAAA GCAGATTTCA TCATCAGTGC CTTTGGCTCC 
ATGCTGAATG ATCCAGCAGT GACGAAGGCC CTGGATCCAA TAAAGCTGAA CCGATGGGGG 
ACTCCTGAGG TGAACAGCGA AACCATGCAG ACCACTGAAC CCTGGGTGTT CGCCGGCGGA 
GACATCGCAG GCTTTGCCAA CACCACCGTG GAGTCTGTCA ACGATGGCAA ACAAGCTTCC 
TGGCACATCC ACAAGTACAT CCAGTCTCTT CATGGTAACA CAATAAGTGC CACTCCCAGA 
CTGCCCTTGT TCCACTGCTC CATTGACACA GTGGACATCA GCGTGGAGAT GTGCGGGATC 
AAGTTTCCTA ACCCCTTTGG ACTGGCCAGC GCTCCTCCCA CGACCAGCGC AGCCATGATC 
CGCAGGGCCT TCGAGCAGGG CTGGGGGTTC GCCCTCACCA AGACCTTTGG CCTGGACAAG 
GATTTGGTGA CCAACGTGTC ACCGCGAATC GTGCGTGGGA CAACCTCAGG TCACATATTC 
GGTCCTGGTC AGGGCTCATT CCTCAACATC GAGCTCATTA GTGAAAAAAC AGCCGCTTAC 
TGGTGCAAGA GCGTGGCTGA ACTCAAAGCC GACTTCCCCA AAAATATTAT CATTGCCAGT 
ATTATGTGCA GTTACAACCA AGCTGACTGG ACTGAGCTGG CAAAGATGGC TCAGGAGTCT 
CAAGCTGATG CTTTGGAGCT GAACCTCTCC TGCCCTCATG GCATGGGGGA GAGAGGTATG 
GGACTGGCCT GTGGACAGGA CCCTGAGCTG GTGAGGAACA TCTGTCGCTG GGTTAGAAAG 
GCCACTAGCA TCCCCTTCTT CGCCAAACTC ACACCCAATG TTACCAACAT CGTTGACATC 
GCCACAGCTG CTTATGAAGG AGGTGCGGAT GGAGTCACAG CCACCAACAC TGTATCTGGA 
CTAATGGCCC TCAAAGCCGA TGCTACACCC TGGCCTGGGA TTGGCAGAGG CGCCAGAACT 
ACATATGGCG GTGTTTCTGG TAATGCAATC CGGCCCATAG CTCTACGTGC AGTTTCAGCT 
ATAGCAAGAG CACTTCCTGG CTTCCCAATC TTGGCCACCG GTGGCATCGA CTCGGCTGAG 
TCTGGATTAC AGTTCCTCCA TGCTGGAGCA TCTGTCTTGC AGGTATGCAG TGCCGTGCAG 
AACCAGGACT TCACAGTGAT CGAGGACTAC TGTTTAGGCC TGAAGGCGCT GCTGTATCTA 
AAAAGCATAG AGGAGCTGCA CGATTGGGAC GGCCAGTCTC CTCCCACCAT TCGCCACCAG 
AAGGGCAAGC CCGTTCCCCA TGTGAGCGAG CTCATTGGAA AGAGTCTGCC TAGCTTCGGG 
CCGTACTTGC AAACGAAGAC TCAGGCACTG GCGAAGTACA AGAAAGATGC CAGCGGTGAT 
GTGATCATGG ACACCGGCGC TGCTAGAGTA AACATCCCCA AAAAACCAAT CCCTAATGTC 
AAAGATGTGA TTGCCCGCGC GCTGAAGCAC ATTGGCGCCT ACCAAGAGCT GGACAACACT 
GAACAAGTGC AGGCCCTGGT GGATCCTGAG ATGTGCATCA ACTGTGGCAA ATGCTACATG 
ACCTGCAATG ACTCAGGCTA CCAGGCTATT AAGTTTGACC CTGAGACTCA TCTTCCTGTA 
ATCACGGACA GCTGCACCGG CTGCACTCTC TGCCTGAGCG TGTGTCCCAT CATTGACTGC 
ATCAAAATGG TTAGCAGGAC CACACCGTAC GAGCCCAAGA GAGGCCTGCC CGTTAATCCC 
GTCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998058.1
CDS	36..3104
Translation	MATMLSKELQDIESILALNPRVKSHANVHSTASKKNEKKHWKRNPERSCDSCVNLENNFDDIKHTTLSERGALREALRCLKCADAPCQKSCPTNLDIKSFITSISNKNYYGAAKAILSDNPLGLTCGMVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEVFSKMGIPQIRNPELPTADNMPKSFHTRIALIGCGPASISCASFLARLGYDNITIFEKQKYIGGLSTSEIPQFRLPYEVVQFEIDLMKDLGVKVVLEKGLGQNGLTLTSLKEEGYQVVYIGIGLPQANRDKIFEGLTTEQGFYTSKDFLPLVAKASKIGMCNCRSQLPKLHGNVIVLGAGDTAFDCATSALRCGARRVFVVFRKGFTNIRAVPEEMEAAKEEKCEFLPFLSPHEVIKKNGRVSGLRFCRTEQQDDGTWIVDEEQIVHLKADFIISAFGSMLNDPAVTKALDPIKLNRWGTPEVNSETMQTTEPWVFAGGDIAGFANTTVESVNDGKQASWHIHKYIQSLHGNTISATPRLPLFHCSIDTVDISVEMCGIKFPNPFGLASAPPTTSAAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVRGTTSGHIFGPGQGSFLNIELISEKTAAYWCKSVAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRKATSIPFFAKLTPNVTNIVDIATAAYEGGADGVTATNTVSGLMALKADATPWPGIGRGARTTYGGVSGNAIRPIALRAVSAIARALPGFPILATGGIDSAESGLQFLHAGASVLQVCSAVQNQDFTVIEDYCLGLKALLYLKSIEELHDWDGQSPPTIRHQKGKPVPHVSELIGKSLPSFGPYLQTKTQALAKYKKDASGDVIMDTGAARVNIPKKPIPNVKDVIARALKHIGAYQELDNTEQVQALVDPEMCINCGKCYMTCNDSGYQAIKFDPETHLPVITDSCTGCTLCLSVCPIIDCIKMVSRTTPYEPKRGLPVNPVC

Target ORF information:

RefSeq Version	NM_212893.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio dihydropyrimidine dehydrogenase b (dpydb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212893.1

ORF Insert Sequence:

ATGGCTACAA TGCTGAGCAA AGAGTTGCAG GATATTGAGA GTATCCTGGC CTTGAACCCG 
AGGGTGAAGA GCCATGCAAA TGTCCATTCC ACTGCCTCAA AGAAGAATGA GAAGAAGCAC 
TGGAAGAGAA ACCCTGAGAG GAGCTGTGAT TCCTGTGTGA ATTTGGAGAA CAACTTTGAT 
GACATCAAGC ACACGACTCT GAGTGAGCGT GGGGCACTTC GGGAGGCGCT GAGATGCCTG 
AAATGCGCAG ACGCTCCATG CCAGAAAAGC TGCCCCACCA ATTTGGATAT CAAATCTTTC 
ATCACCAGCA TTTCCAACAA GAACTACTAC GGTGCTGCTA AAGCAATCCT GTCCGATAAC 
CCACTGGGTC TGACCTGTGG CATGGTGTGT CCCACCTCTG ATCTGTGCGT TGGGGGCTGT 
AACCTCTACG CCTCTGAGGA AGGGCCTATC AATATTGGTG GGCTTCAGCA GTTCGCTACT 
GAGGTGTTCA GTAAGATGGG CATCCCTCAG ATCAGAAATC CAGAGCTTCC CACGGCGGAC 
AACATGCCGA AGAGTTTCCA CACAAGGATC GCTCTCATTG GCTGCGGCCC TGCCAGCATC 
AGCTGCGCCT CCTTCCTGGC CCGGCTAGGA TATGACAACA TCACCATCTT CGAGAAGCAG 
AAATACATTG GTGGCTTGAG CACTTCAGAA ATCCCTCAGT TCCGGTTGCC CTACGAGGTG 
GTGCAGTTTG AGATTGATCT GATGAAGGAT CTTGGCGTAA AGGTTGTTCT TGAGAAGGGA 
CTGGGGCAGA ATGGCTTGAC TCTGACCTCG CTGAAGGAGG AGGGCTATCA AGTGGTCTAC 
ATTGGCATTG GTCTTCCACA AGCAAACAGG GACAAGATTT TCGAGGGCTT GACCACGGAA 
CAGGGATTCT ACACATCAAA GGATTTCCTT CCTTTGGTTG CAAAAGCCAG TAAAATAGGC 
ATGTGTAATT GCCGCTCACA GCTGCCAAAG CTGCATGGGA ATGTGATCGT CCTGGGTGCA 
GGAGACACAG CGTTCGACTG CGCCACCTCT GCTCTCCGCT GTGGAGCTCG ACGAGTCTTT 
GTGGTCTTTA GAAAGGGCTT CACCAACATT CGCGCTGTTC CAGAAGAGAT GGAGGCAGCC 
AAAGAGGAAA AGTGTGAATT CCTGCCCTTC TTGTCACCTC ATGAGGTAAT AAAGAAAAAT 
GGACGTGTCT CAGGCCTGCG CTTCTGCCGC ACAGAGCAGC AGGATGATGG CACCTGGATT 
GTGGACGAGG AGCAAATTGT CCACCTGAAA GCAGATTTCA TCATCAGTGC CTTTGGCTCC 
ATGCTGAATG ATCCAGCAGT GACGAAGGCC CTGGATCCAA TAAAGCTGAA CCGATGGGGG 
ACTCCTGAGG TGAACAGCGA AACCATGCAG ACCACTGAAC CCTGGGTGTT CGCCGGCGGA 
GACATCGCAG GCTTTGCCAA CACCACCGTG GAGTCTGTCA ACGATGGCAA ACAAGCTTCC 
TGGCACATCC ACAAGTACAT CCAGTCTCTT CATGGTAACA CAATAAGTGC CACTCCCAGA 
CTGCCCTTGT TCCACTGCTC CATTGACACA GTGGACATCA GCGTGGAGAT GTGCGGGATC 
AAGTTTCCTA ACCCCTTTGG ACTGGCCAGC GCTCCTCCCA CGACCAGCGC AGCCATGATC 
CGCAGGGCCT TCGAGCAGGG CTGGGGGTTC GCCCTCACCA AGACCTTTGG CCTGGACAAG 
GATTTGGTGA CCAACGTGTC ACCGCGAATC GTGCGTGGGA CAACCTCAGG TCACATATTC 
GGTCCTGGTC AGGGCTCATT CCTCAACATC GAGCTCATTA GTGAAAAAAC AGCCGCTTAC 
TGGTGCAAGA GCGTGGCTGA ACTCAAAGCC GACTTCCCCA AAAATATTAT CATTGCCAGT 
ATTATGTGCA GTTACAACCA AGCTGACTGG ACTGAGCTGG CAAAGATGGC TCAGGAGTCT 
CAAGCTGATG CTTTGGAGCT GAACCTCTCC TGCCCTCATG GCATGGGGGA GAGAGGTATG 
GGACTGGCCT GTGGACAGGA CCCTGAGCTG GTGAGGAACA TCTGTCGCTG GGTTAGAAAG 
GCCACTAGCA TCCCCTTCTT CGCCAAACTC ACACCCAATG TTACCAACAT CGTTGACATC 
GCCACAGCTG CTTATGAAGG AGGTGCGGAT GGAGTCACAG CCACCAACAC TGTATCTGGA 
CTAATGGCCC TCAAAGCCGA TGCTACACCC TGGCCTGGGA TTGGCAGAGG CGCCAGAACT 
ACATATGGCG GTGTTTCTGG TAATGCAATC CGGCCCATAG CTCTACGTGC AGTTTCAGCT 
ATAGCAAGAG CACTTCCTGG CTTCCCAATC TTGGCCACCG GTGGCATCGA CTCGGCTGAG 
TCTGGATTAC AGTTCCTCCA TGCTGGAGCA TCTGTCTTGC AGGTATGCAG TGCCGTGCAG 
AACCAGGACT TCACAGTGAT CGAGGACTAC TGTTTAGGCC TGAAGGCGCT GCTGTATCTA 
AAAAGCATAG AGGAGCTGCA CGATTGGGAC GGCCAGTCTC CTCCCACCAT TCGCCACCAG 
AAGGGCAAGC CCGTTCCCCA TGTGAGCGAG CTCATTGGAA AGAGTCTGCC TAGCTTCGGG 
CCGTACTTGC AAACGAAGAC TCAGGCACTG GCGAAGTACA AGAAAGATGC CAGCGGTGAT 
GTGATCATGG ACACCGGCGC TGCTAGAGTA AACATCCCCA AAAAACCAAT CCCTAATGTC 
AAAGATGTGA TTGCCCGCGC GCTGAAGCAC ATTGGCGCCT ACCAAGAGCT GGACAACACT 
GAACAAGTGC AGGCCCTGGT GGATCCTGAG ATGTGCATCA ACTGTGGCAA ATGCTACATG 
ACCTGCAATG ACTCAGGCTA CCAGGCTATT AAGTTTGACC CTGAGACTCA TCTTCCTGTA 
ATCACGGACA GCTGCACCGG CTGCACTCTC TGCCTGAGCG TGTGTCCCAT CATTGACTGC 
ATCAAAATGG TTAGCAGGAC CACACCGTAC GAGCCCAAGA GAGGCCTGCC CGTTAATCCC 
GTCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Integrative view of ?2,3-sialyltransferases (ST3Gal) molecular and functional evolution in deuterostomes: significance of lineage-specific losses.
Molecular biology and evolution32(4)906-27(2015 Apr)
Petit D,Teppa E,Mir AM,Vicogne D,Thisse C,Thisse B,Filloux C,Harduin-Lepers A