| Gene Symbol | ucp-4 |
| Entrez Gene ID | 179315 |
| Full Name | UnCoupling Protein (mitochondrial substrate carrier) |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » ucp-4 cDNA ORF clone
| Gene Symbol | ucp-4 |
| Entrez Gene ID | 179315 |
| Full Name | UnCoupling Protein (mitochondrial substrate carrier) |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_073013.5 | NP_505414.1 | UnCoupling Protein (mitochondrial substrate carrier) |
| NM_073013.6 | NP_505414.1 | UnCoupling Protein (mitochondrial substrate carrier) |
| Canis lupus familiaris (dog) | SLC25A27 | XP_852329.1 |
| Mus musculus (house mouse) | Slc25a27 | NP_082987.1 |
| Homo sapiens (human) | SLC25A27 | NP_004268.3 |
| SLC25A27 | XP_001103050.1 | |
| Pan troglodytes (chimpanzee) | SLC25A27 | XP_527398.1 |
| Danio rerio (zebrafish) | slc25a27 | NP_956635.1 |
| Arabidopsis thaliana (thale cress) | AT1G14140 | NP_172866.1 |
| Rattus norvegicus (Norway rat) | Slc25a27 | NP_445952.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009603 | XP_318630.3 |
| Caenorhabditis elegans (roundworm) | ucp-4 | NP_505414.1 |
| Xenopus tropicalis (tropical clawed frog) | slc25a27 | NP_001011241.1 |
| Bos taurus (cattle) | SLC25A27 | NP_001193123.1 |
| Drosophila melanogaster (fruit fly) | Ucp4A | NP_001188664.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our results showed that UCP4 knockdown induced an obese phenotype and impaired the insulin-like pathway, possibly via oxidative stress in C. elegans.
Title: Caenorhabditis elegans ucp-4 regulates fat metabolism: suppression of ucp-4 expression induced obese phenotype and caused impairment of insulin like pathway.
novel function for ceUCP4 in the regulation of complex II-based metabolism through an unexpected mechanism involving succinate transport.
Title: Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport.
ucp-4 is a negative regulator of ATP production in C. elegans, but is not required for normal lifespan.
Title: Examination of the requirement for ucp-4, a putative homolog of mammalian uncoupling proteins, for stress tolerance and longevity in C. elegans.
The following ucp-4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ucp-4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa347410 | |
| Clone ID Related Accession (Same CDS sequence) | NM_073013.5 , NM_073013.6 | |
| Accession Version | NM_073013.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | UnCoupling Protein (mitochondrial substrate carrier) | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_073013.4. COMPLETENESS: incomplete on both ends. | |
1 | ATGTCATCAG CAGTCACAAG TACGTCAGAC TCAACTGCGC CGGGCAATTC GCAGACTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_505414.1 |
| CDS | 1..975 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_073013.5 |
1 | ATGTCATCAG CAGTCACAAG TACGTCAGAC TCAACTGCGC CGGGCAATTC GCAGACTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa347410 | |
| Clone ID Related Accession (Same CDS sequence) | NM_073013.5 , NM_073013.6 | |
| Accession Version | NM_073013.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | UnCoupling Protein (mitochondrial substrate carrier) | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_073013.5. COMPLETENESS: incomplete on the 5' end. | |
1 | ATGTCATCAG CAGTCACAAG TACGTCAGAC TCAACTGCGC CGGGCAATTC GCAGACTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_505414.1 |
| CDS | 1..975 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_073013.6 |
1 | ATGTCATCAG CAGTCACAAG TACGTCAGAC TCAACTGCGC CGGGCAATTC GCAGACTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |