| Gene Symbol | pnc-1 |
| Entrez Gene ID | 176833 |
| Full Name | Pyrazinamidase and NiCotinamidase |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pnc-1 cDNA ORF clone
| Gene Symbol | pnc-1 |
| Entrez Gene ID | 176833 |
| Full Name | Pyrazinamidase and NiCotinamidase |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_067475.4 | NP_499876.1 | Isochorismatase domain-containing protein |
| NM_067475.3 | NP_499876.1 | Pyrazinamidase and NiCotinamidase |
| NM_001129336.3 | NP_001122808.1 | Isochorismatase domain-containing protein |
| NM_001129336.2 | NP_001122808.1 | Pyrazinamidase and NiCotinamidase |
| Caenorhabditis elegans (roundworm) | pnc-1 | NP_499876.1 |
| Saccharomyces cerevisiae (baker's yeast) | PNC1 | NP_011478.3 |
| Schizosaccharomyces pombe (fission yeast) | pnc1 | NP_596029.2 |
| Neurospora crassa | NCU00713 | XP_964547.1 |
| Eremothecium gossypii | AGOS_AFR466C | NP_986013.2 |
| Magnaporthe oryzae (rice blast fungus) | MGG_08976 | XP_003714015.1 |
| Caenorhabditis elegans (roundworm) | pnc-2 | NP_001023531.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001435 | XP_321695.5 |
| Kluyveromyces lactis | KLLA0F22242g | XP_456073.1 |
| Drosophila melanogaster (fruit fly) | Naam | NP_001262738.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mutations in the nicotinamidase PNC-1 cause developmental and functional defects in the reproductive system; the development of the gonad is delayed, four uterine cells die by necrosis and the mutant animals are egg-laying defective.
Title: Nicotinamidase modulation of NAD+ biosynthesis and nicotinamide levels separately affect reproductive development and cell survival in C. elegans.
Increased gene dosage of pnc-1 (nicotinamide phosphoribosyltransferase) increases adult survival under conditions of oxidative stress.
Title: The Caenorhabditis elegans nicotinamidase PNC-1 enhances survival.
The following pnc-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pnc-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa343883 | |
| Clone ID Related Accession (Same CDS sequence) | NM_067475.4 , NM_067475.3 | |
| Accession Version | NM_067475.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Isochorismatase domain-containing protein | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_067475.3. | |
1 | ATGTTTCCCT GCCCAAAGCT TATATTCCCA CGTTTAATGG CATTTATTGG GCTCATTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_499876.1 |
| CDS | 167..1174 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_067475.4 |
1 | ATGTTTCCCT GCCCAAAGCT TATATTCCCA CGTTTAATGG CATTTATTGG GCTCATTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa343883 | |
| Clone ID Related Accession (Same CDS sequence) | NM_067475.4 , NM_067475.3 | |
| Accession Version | NM_067475.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Pyrazinamidase and NiCotinamidase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_067475.2. COMPLETENESS: incomplete on both ends. | |
1 | ATGTTTCCCT GCCCAAAGCT TATATTCCCA CGTTTAATGG CATTTATTGG GCTCATTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_499876.1 |
| CDS | 1..1008 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_067475.3 |
1 | ATGTTTCCCT GCCCAAAGCT TATATTCCCA CGTTTAATGG CATTTATTGG GCTCATTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa343890 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001129336.3 , NM_001129336.2 | |
| Accession Version | NM_001129336.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Isochorismatase domain-containing protein | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001129336.2. COMPLETENESS: incomplete on the 5' end. | |
1 | ATGGTACACT CAGACAATTC GGCAACAACC AATAATAACA CAATTCTCGG CAACCAATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001122808.1 |
| CDS | 1..948 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001129336.3 |
1 | ATGGTACACT CAGACAATTC GGCAACAACC AATAATAACA CAATTCTCGG CAACCAATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa343890 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001129336.3 , NM_001129336.2 | |
| Accession Version | NM_001129336.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Pyrazinamidase and NiCotinamidase | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_001129336.1. COMPLETENESS: incomplete on both ends. | |
1 | ATGGTACACT CAGACAATTC GGCAACAACC AATAATAACA CAATTCTCGG CAACCAATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001122808.1 |
| CDS | 1..948 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001129336.2 |
1 | ATGGTACACT CAGACAATTC GGCAACAACC AATAATAACA CAATTCTCGG CAACCAATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |