PROK2 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	PROK2
Entrez Gene ID	387602
Full Name	prokineticin 2
Synonyms	Bv8
General protein information	Preferred Names prokineticin 2 Names prokineticin-2 PK2
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_024982410.1	XP_024838178.1	prokineticin-2 isoform X1
NM_199445.1	NP_955516.1	prokineticin-2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	PROK2	NP_001119600.1
Pan troglodytes (chimpanzee)	PROK2	XP_001141562.1
	PROK2	XP_001083022.1
Mus musculus (house mouse)	Prok2	NP_056583.1
Danio rerio (zebrafish)	prok2	NP_001165870.1
Xenopus tropicalis (tropical clawed frog)	LOC100485995	XP_002938792.1
Canis lupus familiaris (dog)	LOC610873	XP_853528.2
Bos taurus (cattle)	PROK2	NP_955516.1
Rattus norvegicus (Norway rat)	Prok2	NP_001032630.1
Gallus gallus (chicken)	PROK2	XP_001234925.2

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Mitogenic functions of endocrine gland-derived vascular endothelial growth factor and Bombina variegata 8 on steroidogenic adrenocortical cells.
Keramidas M, Faudot C, Cibiel A, Feige JJ, Thomas M
The Journal of endocrinology196(3)473-82(2008 Mar)

The AVIT protein family. Secreted cysteine-rich vertebrate proteins with diverse functions.
Kaser A, Winklmayr M, Lepperdinger G, Kreil G
EMBO reports4(5)469-73(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EG-VEGF/PK1 and Bv8/PK2 thus represent new regulatory peptides acting as autocrine mitogens for endocrine cells
Title: Mitogenic functions of endocrine gland-derived vascular endothelial growth factor and Bombina variegata 8 on steroidogenic adrenocortical cells.

The following PROK2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PROK2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa43756	NM_199445.1 Latest version!	Bos taurus prokineticin 2 (PROK2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa228744	XM_024982410.1 Latest version!	Bos taurus prokineticin 2 (PROK2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PROK2 ( NM_199445.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_955516.1 Bos taurus prokineticin 2 (PROK2), mRNA.

Price & Availability↑

CloneID	OBa43756
Clone ID Related Accession (Same CDS sequence)	NM_199445.1
Accession Version	NM_199445.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 387bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Bos taurus(cattle)
Product	prokineticin-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY192557.1. ##Evidence-Data-START## Transcript exon combination :: AY192557.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145491, SAMN03145497 [ECO:0000348] ##Evidence-Data-END##

ATGAGAAGCT CGCGCTGCGC CCGCCTGCTG CTCCTACTGC TGCTGCCTCC GCTGCTGCTC 
ACACCTCCCG CCGGCGACGC CGCGGTCATC ACCGGGGCCT GCGACAGGGA CCCCCAGTGT 
GGTGGAGGCA TGTGCTGTGC TGTTAGTCTC TGGGTTAAGA GCATACGGAT TTGCACACCG 
ATGGGCAAAG TGGGAGACAG TTGCCATCCG ATGACTCGTA AAAACCATTT TGGAAATGGA 
AGGCAGGAAA GAAGAAAGAG GAAGAGAAGA AGAAAGAAAA AGGTTCCATT TCTTGGGCGG 
AGAATGCATC ACACGTGTCC ATGCCTGCCT GGCTTGGCCT GTTCACGGAC TTCGTTTAAC 
CGATACACAT GTTTAGCCCA GAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_955516.1
CDS	1..387
Translation	MRSSRCARLLLLLLLPPLLLTPPAGDAAVITGACDRDPQCGGGMCCAVSLWVKSIRICTPMGKVGDSCHPMTRKNHFGNGRQERRKRKRRRKKKVPFLGRRMHHTCPCLPGLACSRTSFNRYTCLAQK

Target ORF information:

RefSeq Version	NM_199445.1
Organism	Bos taurus(cattle)
Definition	Bos taurus prokineticin 2 (PROK2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199445.1

ORF Insert Sequence:

ATGAGAAGCT CGCGCTGCGC CCGCCTGCTG CTCCTACTGC TGCTGCCTCC GCTGCTGCTC 
ACACCTCCCG CCGGCGACGC CGCGGTCATC ACCGGGGCCT GCGACAGGGA CCCCCAGTGT 
GGTGGAGGCA TGTGCTGTGC TGTTAGTCTC TGGGTTAAGA GCATACGGAT TTGCACACCG 
ATGGGCAAAG TGGGAGACAG TTGCCATCCG ATGACTCGTA AAAACCATTT TGGAAATGGA 
AGGCAGGAAA GAAGAAAGAG GAAGAGAAGA AGAAAGAAAA AGGTTCCATT TCTTGGGCGG 
AGAATGCATC ACACGTGTCC ATGCCTGCCT GGCTTGGCCT GTTCACGGAC TTCGTTTAAC 
CGATACACAT GTTTAGCCCA GAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PROK2 ( XM_024982410.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024838178.1 Bos taurus prokineticin 2 (PROK2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa228744
Clone ID Related Accession (Same CDS sequence)	XM_024982410.1
Accession Version	XM_024982410.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	prokineticin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037349.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAAGCC CGCGCTGCGC CCGCCTGCTG CTCCTACTGC TGCTGCCTCC GCTGCTGCTC 
ACACCTCCCG CCGGCGACGC CGCGGTCATC ACCGGGGCCT GCGACAGGGA CCCCCAGTGT 
GGTGGAGGCA TGTGCTGTGC TGTTAGTCTC TGGGTTAAGA GCATACGGAT TTGCACACCG 
ATGGGCAAAG TGGGAGACAG TTGCCATCCG ATGACTCGTA AAGTTCCATT TCTTGGGCGG 
AGAATGCATC ACACGTGTCC ATGCCTGCCT GGCTTGGCCT GTTCACGGAC TTCGTTTAAC 
CGATACACAT GTTTAGCCCA GAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024838178.1
CDS	173..499
Translation	MRSPRCARLLLLLLLPPLLLTPPAGDAAVITGACDRDPQCGGGMCCAVSLWVKSIRICTPMGKVGDSCHPMTRKVPFLGRRMHHTCPCLPGLACSRTSFNRYTCLAQK

Target ORF information:

RefSeq Version	XM_024982410.1
Organism	Bos taurus(cattle)
Definition	Bos taurus prokineticin 2 (PROK2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024982410.1

ORF Insert Sequence:

ATGAGAAGCC CGCGCTGCGC CCGCCTGCTG CTCCTACTGC TGCTGCCTCC GCTGCTGCTC 
ACACCTCCCG CCGGCGACGC CGCGGTCATC ACCGGGGCCT GCGACAGGGA CCCCCAGTGT 
GGTGGAGGCA TGTGCTGTGC TGTTAGTCTC TGGGTTAAGA GCATACGGAT TTGCACACCG 
ATGGGCAAAG TGGGAGACAG TTGCCATCCG ATGACTCGTA AAGTTCCATT TCTTGGGCGG 
AGAATGCATC ACACGTGTCC ATGCCTGCCT GGCTTGGCCT GTTCACGGAC TTCGTTTAAC 
CGATACACAT GTTTAGCCCA GAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Mitogenic functions of endocrine gland-derived vascular endothelial growth factor and Bombina variegata 8 on steroidogenic adrenocortical cells.
The Journal of endocrinology196(3)473-82(2008 Mar)
Keramidas M,Faudot C,Cibiel A,Feige JJ,Thomas M

The AVIT protein family. Secreted cysteine-rich vertebrate proteins with diverse functions.
EMBO reports4(5)469-73(2003 May)
Kaser A,Winklmayr M,Lepperdinger G,Kreil G