TYROBP cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	TYROBP
Entrez Gene ID	282390
Full Name	TYRO protein tyrosine kinase binding protein
Synonyms	dap12
General protein information	Preferred Names TYRO protein tyrosine kinase binding protein Names TYRO protein tyrosine kinase-binding protein DNAX-activation protein 12
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005218906.4	XP_005218963.1	TYRO protein tyrosine kinase-binding protein isoform X1
XM_005218906.3	XP_005218963.1	TYRO protein tyrosine kinase-binding protein isoform X1
NM_174627.1	NP_777052.1	TYRO protein tyrosine kinase-binding protein precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	TYROBP	NP_003323.1
	TYROBP	NP_001028039.1
Canis lupus familiaris (dog)	TYROBP	NP_001184046.1
Bos taurus (cattle)	TYROBP	NP_777052.1
Mus musculus (house mouse)	Tyrobp	NP_035792.1
Pan troglodytes (chimpanzee)	TYROBP	NP_001077092.1
Rattus norvegicus (Norway rat)	Tyrobp	NP_997690.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Detecting the effects of selection at the population level in six bovine immune genes.
Freeman AR, Lynn DJ, Murray C, Bradley DG
BMC genetics962(2008 Oct)

Cloning, sequencing, and cell surface expression pattern of bovine immunoreceptor NKG2D and adaptor molecules DAP10 and DAP12.
Fikri Y, Nyabenda J, Content J, Huygen K
Immunogenetics59(8)653-9(2007 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

cloning, sequencing, and cell surface expression pattern
Title: Cloning, sequencing, and cell surface expression pattern of bovine immunoreceptor NKG2D and adaptor molecules DAP10 and DAP12.

The following TYROBP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TYROBP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa41470	NM_174627.1 Latest version!	Bos taurus transmembrane immune signaling adaptor TYROBP (TYROBP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa28601	XM_005218906.4 Latest version!	Bos taurus TYRO protein tyrosine kinase binding protein (TYROBP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
View Old Accession Versions >>
OBa28601	XM_005218906.3	Bos taurus TYRO protein tyrosine kinase binding protein (TYROBP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TYROBP ( NM_174627.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_777052.1 Bos taurus transmembrane immune signaling adaptor TYROBP (TYROBP), mRNA.

Price & Availability↑

CloneID	OBa41470
Clone ID Related Accession (Same CDS sequence)	NM_174627.1
Accession Version	NM_174627.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 330bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-06
Organism	Bos taurus(cattle)
Product	TYRO protein tyrosine kinase-binding protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ419226.1. ##Evidence-Data-START## Transcript exon combination :: AJ419226.1, AV664078.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04335747, SAMN05861752 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGGCA TTAGACCCTC CGACAGGCTC CTATCTCTCC TTCTGACTGT GGGTGGTCTC 
AGCCTCGTCC TGGCCCAGAG TGAATGCAAC TGCTCCTCGG TGAGCCCGGG CGTGCTGGCA 
GGGATCGTGT TGGGGGACCT GATGCTGACC CTCCTCATCG CTCTGGCTGT GTACTACCTG 
GGTCGGCTGG TCCCTCGGGG GCGAGGGGCT ACGGAGGCAG TGACCCGGAA ACAGCACATC 
CCGGAGACAG AGTCGCCTTA TCAGGAGCTC CAAGGCCAGA GGACAGATGT CTACAGCGAC 
CTCAACACAC AGAGGCCGTA TTACAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777052.1
CDS	1..330
Translation	MEGIRPSDRLLSLLLTVGGLSLVLAQSECNCSSVSPGVLAGIVLGDLMLTLLIALAVYYLGRLVPRGRGATEAVTRKQHIPETESPYQELQGQRTDVYSDLNTQRPYYK

Target ORF information:

RefSeq Version	NM_174627.1
Organism	Bos taurus(cattle)
Definition	Bos taurus transmembrane immune signaling adaptor TYROBP (TYROBP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174627.1

ORF Insert Sequence:

ATGGAGGGCA TTAGACCCTC CGACAGGCTC CTATCTCTCC TTCTGACTGT GGGTGGTCTC 
AGCCTCGTCC TGGCCCAGAG TGAATGCAAC TGCTCCTCGG TGAGCCCGGG CGTGCTGGCA 
GGGATCGTGT TGGGGGACCT GATGCTGACC CTCCTCATCG CTCTGGCTGT GTACTACCTG 
GGTCGGCTGG TCCCTCGGGG GCGAGGGGCT ACGGAGGCAG TGACCCGGAA ACAGCACATC 
CCGGAGACAG AGTCGCCTTA TCAGGAGCTC CAAGGCCAGA GGACAGATGT CTACAGCGAC 
CTCAACACAC AGAGGCCGTA TTACAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TYROBP ( XM_005218906.4 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005218963.1 Bos taurus TYRO protein tyrosine kinase binding protein (TYROBP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa28601
Clone ID Related Accession (Same CDS sequence)	XM_005218906.4 , XM_005218906.3
Accession Version	XM_005218906.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	TYRO protein tyrosine kinase-binding protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037345.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005218906.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGCC TTAGACCCTC CGACAGGCTC CTATCTCTCC TTCTGACTGT GGGTGGTCTC 
AGCCTCGTCC TGGCCCAGAG TGAATGCAAC TGCTCCTCGG TGAGCCCGGG CGTGCTGGCA 
GGGATCGTGT TGGGGGACCT GATGCTGACC CTCCTCATCG CTCTGGCTGT GTACTACCTG 
GGTCGGCTGG TCCCTCGGGG GCGAGGGGCT ACGGAGGTGA CCCGGAAACA GCACATCCCG 
GAGACAGAGT CGCCTTATCA GGAGCTCCAA GGCCAGAGGA CAGATGTCTA CAGCGACCTC 
AACACACAGA GGCCGTATTA CAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005218963.1
CDS	105..431
Translation	MEGLRPSDRLLSLLLTVGGLSLVLAQSECNCSSVSPGVLAGIVLGDLMLTLLIALAVYYLGRLVPRGRGATEVTRKQHIPETESPYQELQGQRTDVYSDLNTQRPYYK

Target ORF information:

RefSeq Version	XM_005218906.4
Organism	Bos taurus(cattle)
Definition	Bos taurus TYRO protein tyrosine kinase binding protein (TYROBP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005218906.4

ORF Insert Sequence:

ATGGAGGGCC TTAGACCCTC CGACAGGCTC CTATCTCTCC TTCTGACTGT GGGTGGTCTC 
AGCCTCGTCC TGGCCCAGAG TGAATGCAAC TGCTCCTCGG TGAGCCCGGG CGTGCTGGCA 
GGGATCGTGT TGGGGGACCT GATGCTGACC CTCCTCATCG CTCTGGCTGT GTACTACCTG 
GGTCGGCTGG TCCCTCGGGG GCGAGGGGCT ACGGAGGTGA CCCGGAAACA GCACATCCCG 
GAGACAGAGT CGCCTTATCA GGAGCTCCAA GGCCAGAGGA CAGATGTCTA CAGCGACCTC 
AACACACAGA GGCCGTATTA CAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TYROBP ( XM_005218906.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005218963.1 Bos taurus TYRO protein tyrosine kinase binding protein (TYROBP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa28601
Clone ID Related Accession (Same CDS sequence)	XM_005218906.4 , XM_005218906.3
Accession Version	XM_005218906.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	TYRO protein tyrosine kinase-binding protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104465.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005218906.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGCC TTAGACCCTC CGACAGGCTC CTATCTCTCC TTCTGACTGT GGGTGGTCTC 
AGCCTCGTCC TGGCCCAGAG TGAATGCAAC TGCTCCTCGG TGAGCCCGGG CGTGCTGGCA 
GGGATCGTGT TGGGGGACCT GATGCTGACC CTCCTCATCG CTCTGGCTGT GTACTACCTG 
GGTCGGCTGG TCCCTCGGGG GCGAGGGGCT ACGGAGGTGA CCCGGAAACA GCACATCCCG 
GAGACAGAGT CGCCTTATCA GGAGCTCCAA GGCCAGAGGA CAGATGTCTA CAGCGACCTC 
AACACACAGA GGCCGTATTA CAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005218963.1
CDS	84..410
Translation	MEGLRPSDRLLSLLLTVGGLSLVLAQSECNCSSVSPGVLAGIVLGDLMLTLLIALAVYYLGRLVPRGRGATEVTRKQHIPETESPYQELQGQRTDVYSDLNTQRPYYK

Target ORF information:

RefSeq Version	XM_005218906.3
Organism	Bos taurus(cattle)
Definition	Bos taurus TYRO protein tyrosine kinase binding protein (TYROBP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005218906.3

ORF Insert Sequence:

ATGGAGGGCC TTAGACCCTC CGACAGGCTC CTATCTCTCC TTCTGACTGT GGGTGGTCTC 
AGCCTCGTCC TGGCCCAGAG TGAATGCAAC TGCTCCTCGG TGAGCCCGGG CGTGCTGGCA 
GGGATCGTGT TGGGGGACCT GATGCTGACC CTCCTCATCG CTCTGGCTGT GTACTACCTG 
GGTCGGCTGG TCCCTCGGGG GCGAGGGGCT ACGGAGGTGA CCCGGAAACA GCACATCCCG 
GAGACAGAGT CGCCTTATCA GGAGCTCCAA GGCCAGAGGA CAGATGTCTA CAGCGACCTC 
AACACACAGA GGCCGTATTA CAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Detecting the effects of selection at the population level in six bovine immune genes.
BMC genetics962(2008 Oct)
Freeman AR,Lynn DJ,Murray C,Bradley DG

Cloning, sequencing, and cell surface expression pattern of bovine immunoreceptor NKG2D and adaptor molecules DAP10 and DAP12.
Immunogenetics59(8)653-9(2007 Aug)
Fikri Y,Nyabenda J,Content J,Huygen K