AChE-2 cDNA ORF clone, Apis mellifera(honey bee)

Gene
Clones
gRNAs

Summary

Gene Symbol	AChE-2
Entrez Gene ID	406104
Full Name	acetylcholinesterase 2
Synonyms	ACE2,Ache,GB14873
Gene Type	protein-coding
Organism	Apis mellifera(honey bee)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001040230.1	NP_001035320.1	acetylcholinesterase 2 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Different response of acetylcholinesterases in salt- and detergent-soluble fractions of honeybee haemolymph, head and thorax after exposure to diazinon.
Glavan G, Kos M, Bo?i? J, Drobne D, Saboti? J, Kokalj AJ
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP2058-14(2017 Dec)

Finding the missing honey bee genes: lessons learned from a genome upgrade.
Elsik CG, Worley KC, Bennett AK, Beye M, Camara F, Childers CP, de Graaf DC, Debyser G, Deng J, Devreese B, Elhaik E, Evans JD, Foster LJ, Graur D, Guigo R, , Hoff KJ, Holder ME, Hudson ME, Hunt GJ, Jiang H, Joshi V, Khetani RS, Kosarev P, Kovar CL, Ma J, Maleszka R, Moritz RF, Munoz-Torres MC, Murphy TD, Muzny DM, Newsham IF, Reese JT, Robertson HM, Robinson GE, Rueppell O, Solovyev V, Stanke M, Stolle E, Tsuruda JM, Vaerenbergh MV, Waterhouse RM, Weaver DB, Whitfield CW, Wu Y, Zdobnov EM, Zhang L, Zhu D, Gibbs RA,
BMC genomics1586(2014 Jan)

Insights into social insects from the genome of the honeybee Apis mellifera.

Nature443(7114)931-49(2006 Oct)

Changes in neuronal acetylcholinesterase gene expression and division of labor in honey bee colonies.
Shapira M, Thompson CK, Soreq H, Robinson GE
Journal of molecular neuroscience : MN17(1)1-12(2001 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following AChE-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AChE-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHd00472	NM_001040230.1 Latest version!	Apis mellifera acetylcholinesterase 2 (AChE-2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AChE-2 ( NM_001040230.1 ) cDNA ORF clone, Apis mellifera(honey bee) -> NP_001035320.1 Apis mellifera acetylcholinesterase 2 (AChE-2), mRNA.

Price & Availability↑

CloneID	OHd00472
Clone ID Related Accession (Same CDS sequence)	NM_001040230.1
Accession Version	NM_001040230.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1887bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Apis mellifera(honey bee)
Product	acetylcholinesterase 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB181702.1. ##Evidence-Data-START## Transcript exon combination :: AB181702.1 [ECO:0000332] ##Evidence-Data-END##

ATGACTACGA GGATCCTACT CCTGTTCTTC CTCCTTCTCT CCTCGTGCAC GCGTCCTAGC 
AGGGGCAACG CAGTTCCCTC CTCGCAGAGG GGCAACGTGC ACAACGACCC CCTGGTCGTG 
GAGACGACCA GCGGCCTCGT GCGCGGTTTC CCCCGCACCG TGTTGGACAA GGAGGTGCAC 
GTGTTCTACG GGATACCGTT CGCCAAACCC CCGATCGGCC CCCTCCGTTT CAGGAAACCG 
TTGCCGATCG AGCCGTGGCA CGGCGTGTTG AACGCGACCG TGTTGCCGAA CAGTTGCTAC 
CAGGAGAGAT ACGAGTATTT CCCCGGGTTC CCGGGCGAGG AGATGTGGAA CCCGAACACC 
AACATATCCG AGGACTGTTT GTACCTGAAC ATATGGGTGC CACAGAAGTA TAGATTGAGG 
CACAAGGGAG ACGGTTCGCC GGGTGGCAAC GGGGGTCCCA GGAACGGTTT GCTCCCTTTA 
CTGGTGTGGA TCTACGGGGG TGGGTTCATG AGCGGCACGG CAACCCTGGA CGTGTACAAC 
GCGGACATAA TGGCGGCTAC GAGCAACGTT ATAATAGCAT CGATGCAGTA CAGGGTGGGC 
GCGTTCGGTT TCCTCTATCT GAACAAACAC TTCACGAACA GCGAGGAGGC GCCGGGGAAC 
ATGGGTCTTT GGGATCAGGC GCTCGCGCTT AGATGGCTGA GGGACAACGC CGAGGCGTTC 
GGCGGGGATC CGGAGTTGAT CACGATATTC GGCGAGTCGG CGGGGGGCAG CTCCGTCTCC 
CTGCACCTCA TCTCGCCCGT GACGAGGGGA CTGGTGCGCC GCGGCATACT GCAGAGCGGC 
ACCCTCAACG CTCCCTGGAG TTACATGAGC GGGGAGAAGG CGAACGAGGT CGCGACGATA 
CTGGTCGACG ATTGCGGATG CAACTCGACC ATGCTGAACG AGAACCCGGC CAGGGTGATG 
GCGTGTATGA GGTCCGTGGA CGCGAAGACC ATATCCGTTC AACAGTGGAA CAGTTATTGG 
GGGATTCTAG GCTTCCCCTC GGCGCCCACC ATCGACGGTA TCTTCCTTCC CAAGCATCCT 
CTCGATCTGT TGAGGGAAGC GGACTTCAAG GACACAGAGA TACTGATCGG TAACAACGAG 
AACGAGGGAA CTTATTTCAT CCTTTACGAC TTCAACGATA TTTTCGAGAA GGACCAGGCC 
AGTTTCTTGG AACGAGAAAG ATTCCTTGGT ATTATTAACA ACATCTTCAA GAACATGTCT 
CAAATTGAAC GAGAAGCCAT TACTTTCCAG TACACGGACT GGGAGGAGGT GTACAACGGG 
TATATTTACC AAAAAATGGT CGCGGACGTG GTTGGCGACT ACTTCTTCAT CTGTCCCTCG 
ATCCACTTCG CCCAATTGTT CGCCGATCGT GGCATGAAGG TCTACTACTA CTTCTTCACG 
CAAAGGACGA GCACCAATCT ATGGGGCGAG TGGATGGGCG TATTGCACGG TGACGAGGTT 
GAGTACGTGT TCGGCCATCC CCTGAACAAG TCTCTCAAGT ACAGCGACAA GGAACGAGAC 
CTGTCATTGA GGATGATACT CTACTTCTCC GAATTCGCCT ATTTGGGAAA ACCAACGAAA 
GAAGACTCTG AATGGCCATC GTATTCGAGA GACGAACCAA AATACTTCAT CTTCGATGCG 
GAGAAGACTG GACTTGGTAA AGGGCCACGT ACCACGTATT GTGCTTTCTG GAACGAATTT 
CTACCAAAGT TGAAAGGAAT ACCAGATCCA GYGCCCAATA CCTGCAAGGT GATAGCCTCG 
AGCGTGTCGG CCGGCGAGGA GGGGCTAGGA AATTCCCTAG CGATCACGGC GCTGTCGTCG 
ATCCTTGTCC TGTCGAGAGT GATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035320.1
CDS	204..2090
Translation	MTTRILLLFFLLLSSCTRPSRGNAVPSSQRGNVHNDPLVVETTSGLVRGFPRTVLDKEVHVFYGIPFAKPPIGPLRFRKPLPIEPWHGVLNATVLPNSCYQERYEYFPGFPGEEMWNPNTNISEDCLYLNIWVPQKYRLRHKGDGSPGGNGGPRNGLLPLLVWIYGGGFMSGTATLDVYNADIMAATSNVIIASMQYRVGAFGFLYLNKHFTNSEEAPGNMGLWDQALALRWLRDNAEAFGGDPELITIFGESAGGSSVSLHLISPVTRGLVRRGILQSGTLNAPWSYMSGEKANEVATILVDDCGCNSTMLNENPARVMACMRSVDAKTISVQQWNSYWGILGFPSAPTIDGIFLPKHPLDLLREADFKDTEILIGNNENEGTYFILYDFNDIFEKDQASFLERERFLGIINNIFKNMSQIEREAITFQYTDWEEVYNGYIYQKMVADVVGDYFFICPSIHFAQLFADRGMKVYYYFFTQRTSTNLWGEWMGVLHGDEVEYVFGHPLNKSLKYSDKERDLSLRMILYFSEFAYLGKPTKEDSEWPSYSRDEPKYFIFDAEKTGLGKGPRTTYCAFWNEFLPKLKGIPDPnullPNTCKVIASSVSAGEEGLGNSLAITALSSILVLSRVI

Target ORF information:

RefSeq Version	NM_001040230.1
Organism	Apis mellifera(honey bee)
Definition	Apis mellifera acetylcholinesterase 2 (AChE-2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040230.1

ORF Insert Sequence:

ATGACTACGA GGATCCTACT CCTGTTCTTC CTCCTTCTCT CCTCGTGCAC GCGTCCTAGC 
AGGGGCAACG CAGTTCCCTC CTCGCAGAGG GGCAACGTGC ACAACGACCC CCTGGTCGTG 
GAGACGACCA GCGGCCTCGT GCGCGGTTTC CCCCGCACCG TGTTGGACAA GGAGGTGCAC 
GTGTTCTACG GGATACCGTT CGCCAAACCC CCGATCGGCC CCCTCCGTTT CAGGAAACCG 
TTGCCGATCG AGCCGTGGCA CGGCGTGTTG AACGCGACCG TGTTGCCGAA CAGTTGCTAC 
CAGGAGAGAT ACGAGTATTT CCCCGGGTTC CCGGGCGAGG AGATGTGGAA CCCGAACACC 
AACATATCCG AGGACTGTTT GTACCTGAAC ATATGGGTGC CACAGAAGTA TAGATTGAGG 
CACAAGGGAG ACGGTTCGCC GGGTGGCAAC GGGGGTCCCA GGAACGGTTT GCTCCCTTTA 
CTGGTGTGGA TCTACGGGGG TGGGTTCATG AGCGGCACGG CAACCCTGGA CGTGTACAAC 
GCGGACATAA TGGCGGCTAC GAGCAACGTT ATAATAGCAT CGATGCAGTA CAGGGTGGGC 
GCGTTCGGTT TCCTCTATCT GAACAAACAC TTCACGAACA GCGAGGAGGC GCCGGGGAAC 
ATGGGTCTTT GGGATCAGGC GCTCGCGCTT AGATGGCTGA GGGACAACGC CGAGGCGTTC 
GGCGGGGATC CGGAGTTGAT CACGATATTC GGCGAGTCGG CGGGGGGCAG CTCCGTCTCC 
CTGCACCTCA TCTCGCCCGT GACGAGGGGA CTGGTGCGCC GCGGCATACT GCAGAGCGGC 
ACCCTCAACG CTCCCTGGAG TTACATGAGC GGGGAGAAGG CGAACGAGGT CGCGACGATA 
CTGGTCGACG ATTGCGGATG CAACTCGACC ATGCTGAACG AGAACCCGGC CAGGGTGATG 
GCGTGTATGA GGTCCGTGGA CGCGAAGACC ATATCCGTTC AACAGTGGAA CAGTTATTGG 
GGGATTCTAG GCTTCCCCTC GGCGCCCACC ATCGACGGTA TCTTCCTTCC CAAGCATCCT 
CTCGATCTGT TGAGGGAAGC GGACTTCAAG GACACAGAGA TACTGATCGG TAACAACGAG 
AACGAGGGAA CTTATTTCAT CCTTTACGAC TTCAACGATA TTTTCGAGAA GGACCAGGCC 
AGTTTCTTGG AACGAGAAAG ATTCCTTGGT ATTATTAACA ACATCTTCAA GAACATGTCT 
CAAATTGAAC GAGAAGCCAT TACTTTCCAG TACACGGACT GGGAGGAGGT GTACAACGGG 
TATATTTACC AAAAAATGGT CGCGGACGTG GTTGGCGACT ACTTCTTCAT CTGTCCCTCG 
ATCCACTTCG CCCAATTGTT CGCCGATCGT GGCATGAAGG TCTACTACTA CTTCTTCACG 
CAAAGGACGA GCACCAATCT ATGGGGCGAG TGGATGGGCG TATTGCACGG TGACGAGGTT 
GAGTACGTGT TCGGCCATCC CCTGAACAAG TCTCTCAAGT ACAGCGACAA GGAACGAGAC 
CTGTCATTGA GGATGATACT CTACTTCTCC GAATTCGCCT ATTTGGGAAA ACCAACGAAA 
GAAGACTCTG AATGGCCATC GTATTCGAGA GACGAACCAA AATACTTCAT CTTCGATGCG 
GAGAAGACTG GACTTGGTAA AGGGCCACGT ACCACGTATT GTGCTTTCTG GAACGAATTT 
CTACCAAAGT TGAAAGGAAT ACCAGATCCA GYGCCCAATA CCTGCAAGGT GATAGCCTCG 
AGCGTGTCGG CCGGCGAGGA GGGGCTAGGA AATTCCCTAG CGATCACGGC GCTGTCGTCG 
ATCCTTGTCC TGTCGAGAGT GATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Different response of acetylcholinesterases in salt- and detergent-soluble fractions of honeybee haemolymph, head and thorax after exposure to diazinon.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP2058-14(2017 Dec)
Glavan G,Kos M,Bo?i? J,Drobne D,Saboti? J,Kokalj AJ

Finding the missing honey bee genes: lessons learned from a genome upgrade.
BMC genomics1586(2014 Jan)
Elsik CG,Worley KC,Bennett AK,Beye M,Camara F,Childers CP,de Graaf DC,Debyser G,Deng J,Devreese B,Elhaik E,Evans JD,Foster LJ,Graur D,Guigo R,,Hoff KJ,Holder ME,Hudson ME,Hunt GJ,Jiang H,Joshi V,Khetani RS,Kosarev P,Kovar CL,Ma J,Maleszka R,Moritz RF,Munoz-Torres MC,Murphy TD,Muzny DM,Newsham IF,Reese JT,Robertson HM,Robinson GE,Rueppell O,Solovyev V,Stanke M,Stolle E,Tsuruda JM,Vaerenbergh MV,Waterhouse RM,Weaver DB,Whitfield CW,Wu Y,Zdobnov EM,Zhang L,Zhu D,Gibbs RA,

Insights into social insects from the genome of the honeybee Apis mellifera.
Nature443(7114)931-49(2006 Oct)

Changes in neuronal acetylcholinesterase gene expression and division of labor in honey bee colonies.
Journal of molecular neuroscience : MN17(1)1-12(2001 Aug)
Shapira M,Thompson CK,Soreq H,Robinson GE