tnfsf10.S cDNA ORF clone, Xenopus laevis(African clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	tnfsf10.S
Entrez Gene ID	100316914
Full Name	TNF superfamily member 10 S homeolog
Synonyms	apo-2l,apo2l,cd253,tl2,tnfsf10,trail,trail1,xtrail1
General protein information	Preferred Names TNF superfamily member 10 S homeolog Names TNF superfamily member 10 S homeolog TNF-related apoptosis-inducing ligand 1 tumor necrosis factor (ligand) superfamily, member 10 tumor necrosis factor related apoptosis inducing ligand 1 tumor necrosis factor superfamily member 10 S homeolog
Gene Type	protein-coding
Organism	Xenopus laevis(African clawed frog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001170444.1	NP_001163915.1	TNF superfamily member 10 S homeolog

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL1) enhances the transition of red blood cells from the larval to adult type during metamorphosis in Xenopus.
Tamura K, Mawaribuchi S, Yoshimoto S, Shiba T, Takamatsu N, Ito M
Blood115(4)850-9(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

xTRAIL1 can cause apoptosis, probably mediated through xDR-Ms, in larval red blood cells, but may not kill adult RBCs, presumably owing to PKC activation, as part of the mechanism for RBC switching
Title: Tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL1) enhances the transition of red blood cells from the larval to adult type during metamorphosis in Xenopus.

The following tnfsf10.S gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tnfsf10.S cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OAf05280	NM_001170444.1 Latest version!	Xenopus laevis TNF superfamily member 10 S homeolog (tnfsf10.S), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

tnfsf10.S ( NM_001170444.1 ) cDNA ORF clone, Xenopus laevis(African clawed frog) -> NP_001163915.1 Xenopus laevis TNF superfamily member 10 S homeolog (tnfsf10.S), mRNA.

Price & Availability↑

CloneID	OAf05280
Clone ID Related Accession (Same CDS sequence)	NM_001170444.1
Accession Version	NM_001170444.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-01
Organism	Xenopus laevis(African clawed frog)
Product	TNF superfamily member 10 S homeolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB496421.1. ##Evidence-Data-START## Transcript exon combination :: AB496421.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00012418, SAMD00012419 [ECO:0000348] ##Evidence-Data-END##

ATGATCACCA CCACTGCTGC ATCCCATCCC TTTTCCCTCT GTGGACTTGT ACTGCTTTTT 
GCAGTATTAC TCCAGTCTGT CTTTGTTGCT GTCACATATA TATACTTCAC TAATGAACTT 
AAACAGCTCC GCGAAACCTA CACCAGGAGC AACATTGCTT GTTTAACTGG AGAAGATGTT 
GGAGATTTAT TCCGACCCTC TACTTCTGAG GATGGATATG AAAGGAATGA TCCTTGCTGG 
GAAATAAAGT CCCACTTGTA CATTTTAATC AGAAAGATCG TTTTGAAAAA TTACAAATCA 
GACAATACAG GTAAAGTTAA AGAAACTCCA TTGGCTGTTT ATCAAAAAGA AGAAGATCCT 
GCTGGAGTCA TCGCTGCACA TGTAACTGGA GACAGCAGGA AAGTTTTCCC CCCGGAAAAT 
GCCTTCCTGA AGAAGTATAA TGGGCAGAAA ATACAAGGAT GGAAATCCCA CAGATCTCCT 
TCTTTTCTAA GCAACGTAGA AGTTGAAAAC GGTGAGCTAA TTATTAGAAA AAGTGGCTTT 
TACTACATTT ATTCTCAGAC ATACTTTCGG CAACGCTTCA ATAGGGGAAC AGAAGAAAGA 
AAAGGGAAAC AATTAGTTCA GCAGATTTAC AAGGTAACAA GCTACCCAGA ACCACTTCTT 
TTAATGAAAA ATGTTAAAAC AATGTGTTGG TCTAAAGAGG CAGATTATGG GCTGCATTCC 
ATCTATCAAG GAGGGGTTTT CAAACTCAAC GAAAATGATC GTATTTTTGT CACAGTCAGT 
GATATTAGTC TGATTGATAT GGATGAAAAC GCAACATTCG TGGGAGCTTT TTTGGTGGTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001163915.1
CDS	25..867
Translation	MITTTAASHPFSLCGLVLLFAVLLQSVFVAVTYIYFTNELKQLRETYTRSNIACLTGEDVGDLFRPSTSEDGYERNDPCWEIKSHLYILIRKIVLKNYKSDNTGKVKETPLAVYQKEEDPAGVIAAHVTGDSRKVFPPENAFLKKYNGQKIQGWKSHRSPSFLSNVEVENGELIIRKSGFYYIYSQTYFRQRFNRGTEERKGKQLVQQIYKVTSYPEPLLLMKNVKTMCWSKEADYGLHSIYQGGVFKLNENDRIFVTVSDISLIDMDENATFVGAFLVV

Target ORF information:

RefSeq Version	NM_001170444.1
Organism	Xenopus laevis(African clawed frog)
Definition	Xenopus laevis TNF superfamily member 10 S homeolog (tnfsf10.S), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001170444.1

ORF Insert Sequence:

ATGATCACCA CCACTGCTGC ATCCCATCCC TTTTCCCTCT GTGGACTTGT ACTGCTTTTT 
GCAGTATTAC TCCAGTCTGT CTTTGTTGCT GTCACATATA TATACTTCAC TAATGAACTT 
AAACAGCTCC GCGAAACCTA CACCAGGAGC AACATTGCTT GTTTAACTGG AGAAGATGTT 
GGAGATTTAT TCCGACCCTC TACTTCTGAG GATGGATATG AAAGGAATGA TCCTTGCTGG 
GAAATAAAGT CCCACTTGTA CATTTTAATC AGAAAGATCG TTTTGAAAAA TTACAAATCA 
GACAATACAG GTAAAGTTAA AGAAACTCCA TTGGCTGTTT ATCAAAAAGA AGAAGATCCT 
GCTGGAGTCA TCGCTGCACA TGTAACTGGA GACAGCAGGA AAGTTTTCCC CCCGGAAAAT 
GCCTTCCTGA AGAAGTATAA TGGGCAGAAA ATACAAGGAT GGAAATCCCA CAGATCTCCT 
TCTTTTCTAA GCAACGTAGA AGTTGAAAAC GGTGAGCTAA TTATTAGAAA AAGTGGCTTT 
TACTACATTT ATTCTCAGAC ATACTTTCGG CAACGCTTCA ATAGGGGAAC AGAAGAAAGA 
AAAGGGAAAC AATTAGTTCA GCAGATTTAC AAGGTAACAA GCTACCCAGA ACCACTTCTT 
TTAATGAAAA ATGTTAAAAC AATGTGTTGG TCTAAAGAGG CAGATTATGG GCTGCATTCC 
ATCTATCAAG GAGGGGTTTT CAAACTCAAC GAAAATGATC GTATTTTTGT CACAGTCAGT 
GATATTAGTC TGATTGATAT GGATGAAAAC GCAACATTCG TGGGAGCTTT TTTGGTGGTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL1) enhances the transition of red blood cells from the larval to adult type during metamorphosis in Xenopus.
Blood115(4)850-9(2010 Jan)
Tamura K,Mawaribuchi S,Yoshimoto S,Shiba T,Takamatsu N,Ito M