| Gene Symbol | STAT3 |
| Entrez Gene ID | 733648 |
| Full Name | signal transducer and activator of transcription 3 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(Pig) |
| Genome |
ORF » Species Summary » Sus scrofa » STAT3 cDNA ORF clone
| Gene Symbol | STAT3 |
| Entrez Gene ID | 733648 |
| Full Name | signal transducer and activator of transcription 3 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(Pig) |
| Genome |
| mRNA | Protein | Name |
|---|---|---|
| XM_005668829.2 | XP_005668886.1 | signal transducer and activator of transcription 3 isoform X3 |
| XM_005668827.2 | XP_005668884.1 | signal transducer and activator of transcription 3 isoform X1 |
| NM_001044580.1 | NP_001038045.1 | signal transducer and activator of transcription 3 |
| XM_005668828.2 | XP_005668885.1 | signal transducer and activator of transcription 3 isoform X2 |
STAT3 as a common signal of ischemic conditioning: a lesson on "rigor and reproducibility" in preclinical studies on cardioprotection.
Kleinbongard P, Skyschally A, Gent S, Pesch M, Heusch G
Basic research in cardiology113(1)3(2017 Nov)
Suppressor of cytokine signaling 3 plays an important role in porcine circovirus type 2 subclinical infection by downregulating proinflammatory responses.
Zhu X, Bai J, Liu P, Wang X, Jiang P
Scientific reports632538(2016 Sep)
Developmental expression of STATs, nuclear factor-?B and inflammatory genes in the jejunum of piglets during weaning.
Yi H, Jiang D, Zhang L, Xiong H, Han F, Wang Y
International immunopharmacology36199-204(2016 Jul)
Maternal gestational betaine supplementation-mediated suppression of hepatic cyclin D2 and presenilin1 gene in newborn piglets is associated with epigenetic regulation of the STAT3-dependent pathway.
Cai D, Yuan M, Jia Y, Liu H, Hu Y, Zhao R
The Journal of nutritional biochemistry26(12)1622-31(2015 Dec)
Leukemia inhibitory factor promotes porcine oocyte maturation and is accompanied by activation of signal transducer and activator of transcription 3.
Dang-Nguyen TQ, Haraguchi S, Kikuchi K, Somfai T, Bod? S, Nagai T
Molecular reproduction and development81(3)230-9(2014 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
this study shows that weaning caused severe inflammation associated with activation of the STAT3 pathway in the jejunum of piglets
Title: Developmental expression of STATs, nuclear factor-?B and inflammatory genes in the jejunum of piglets during weaning.
maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 and PSEN1 genes via a STAT3-dependent pathway
Title: Maternal gestational betaine supplementation-mediated suppression of hepatic cyclin D2 and presenilin1 gene in newborn piglets is associated with epigenetic regulation of the STAT3-dependent pathway.
Studied effect of recombinant porcine leukemia inhibitory factor on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF-supplemented media.
Title: Leukemia inhibitory factor promotes porcine oocyte maturation and is accompanied by activation of signal transducer and activator of transcription 3.
Data suggest that IL-6 (interleukin 6) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).
Title: Interleukin-6 enhances porcine parthenote development in vitro, through the IL-6/Stat3 signaling pathway.
Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.
Title: Mitochondrial STAT3 activation and cardioprotection by ischemic postconditioning in pigs with regional myocardial ischemia/reperfusion.
The following STAT3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STAT3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe30492 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001044580.1 | |
| Accession Version | NM_001044580.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2313bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-11-15 | |
| Organism | Sus scrofa(pig) | |
| Product | signal transducer and activator of transcription 3 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ470570.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ470570.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02584787 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCCAAT GGAATCAGCT ACAGCAGCTG GACACACGGT ACCTGGAGCA GCTTCATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001038045.1 |
| CDS | 137..2449 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001044580.1 |
1 | ATGGCCCAAT GGAATCAGCT ACAGCAGCTG GACACACGGT ACCTGGAGCA GCTTCATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe18652 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005668827.2 | |
| Accession Version | XM_005668827.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-09-10 | |
| Organism | Sus scrofa(Pig) | |
| Product | signal transducer and activator of transcription 3 isoform X1 | |
| Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003611500.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005668827.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCCCAAT GGAATCAGCT ACAGCAGCTG GACACACGGT ACCTGGAGCA GCTTCATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005668884.1 |
| CDS | 234..2543 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005668827.2 |
1 | ATGGCCCAAT GGAATCAGCT ACAGCAGCTG GACACACGGT ACCTGGAGCA GCTTCATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe18653 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005668828.2 | |
| Accession Version | XM_005668828.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2169bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-09-10 | |
| Organism | Sus scrofa(Pig) | |
| Product | signal transducer and activator of transcription 3 isoform X2 | |
| Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003611500.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005668828.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCCCAAT GGAATCAGCT ACAGCAGCTG GACACACGGT ACCTGGAGCA GCTTCATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005668885.1 |
| CDS | 235..2403 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005668828.2 |
1 | ATGGCCCAAT GGAATCAGCT ACAGCAGCTG GACACACGGT ACCTGGAGCA GCTTCATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe18654 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005668829.2 | |
| Accession Version | XM_005668829.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2166bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-09-10 | |
| Organism | Sus scrofa(Pig) | |
| Product | signal transducer and activator of transcription 3 isoform X3 | |
| Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003611500.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005668829.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCCCAAT GGAATCAGCT ACAGCAGCTG GACACACGGT ACCTGGAGCA GCTTCATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005668886.1 |
| CDS | 235..2400 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005668829.2 |
1 | ATGGCCCAAT GGAATCAGCT ACAGCAGCTG GACACACGGT ACCTGGAGCA GCTTCATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
STAT3 as a common signal of ischemic conditioning: a lesson on "rigor and reproducibility" in preclinical studies on cardioprotection. |
Suppressor of cytokine signaling 3 plays an important role in porcine circovirus type 2 subclinical infection by downregulating proinflammatory responses. |
Developmental expression of STATs, nuclear factor-?B and inflammatory genes in the jejunum of piglets during weaning. |
Maternal gestational betaine supplementation-mediated suppression of hepatic cyclin D2 and presenilin1 gene in newborn piglets is associated with epigenetic regulation of the STAT3-dependent pathway. |
Leukemia inhibitory factor promotes porcine oocyte maturation and is accompanied by activation of signal transducer and activator of transcription 3. |