| Gene Symbol | IL17A |
| Entrez Gene ID | 449530 |
| Full Name | interleukin 17A |
| Synonyms | IL17 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
ORF » Species Summary » Sus scrofa » IL17A cDNA ORF clone
| Gene Symbol | IL17A |
| Entrez Gene ID | 449530 |
| Full Name | interleukin 17A |
| Synonyms | IL17 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| mRNA | Protein | Name |
|---|---|---|
| NM_001005729.1 | NP_001005729.1 | interleukin-17A precursor |
Crusted scabies is associated with increased IL-17 secretion by skin T cells.
Liu X, Walton SF, Murray HC, King M, Kelly A, Holt DC, Currie BJ, McCarthy JS, Mounsey KE
Parasite immunology36(11)594-604(2014 Nov)
Effects of dietary supplementation with Laminaria hyperborea, Laminaria digitata, and Saccharomyces cerevisiae on the IL-17 pathway in the porcine colon.
Ryan MT, O'Shea CJ, Collins CB, O'Doherty JV, Sweeney T
Journal of animal science90 Suppl 4263-5(2012 Dec)
CD4+ and ??TCR+ T lymphocytes are sources of interleukin-17 in swine.
Stepanova H, Mensikova M, Chlebova K, Faldyna M
Cytokine58(2)152-7(2012 May)
Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC, thymus, and lung lymphocytes of young pigs.
Kiros TG, van Kessel J, Babiuk LA, Gerdts V
Veterinary immunology and immunopathology144(3-4)448-54(2011 Dec)
Cloning and characterization of Swine interleukin-17, preferentially expressed in the intestines.
Katoh S, Kitazawa H, Shimosato T, Tohno M, Kawai Y, Saito T
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research24(9)553-9(2004 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.
Title: Crusted scabies is associated with increased IL-17 secretion by skin T cells.
Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.
Title: Effects of dietary supplementation with Laminaria hyperborea, Laminaria digitata, and Saccharomyces cerevisiae on the IL-17 pathway in the porcine colon.
conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3(+)CD4(+) and CD3(+)gammadeltaTCR(+).
Title: CD4+ and ??TCR+ T lymphocytes are sources of interleukin-17 in swine.
Cloning and expression of interleukin-17.
Title: Cloning and characterization of Swine interleukin-17, preferentially expressed in the intestines.
The following IL17A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL17A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe01381 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001005729.1 | |
| Accession Version | NM_001005729.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Sus scrofa(pig) | |
| Product | interleukin-17A precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB102693.1. ##Evidence-Data-START## Transcript exon combination :: AB102693.1, FJ196861.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01083986, SAMN02364669 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGACTCCTG TGAGATCCTC GTCCCTGTCA CTGCTGCTTC TGCTGAGCCT GGTGGCTCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001005729.1 |
| CDS | 57..518 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001005729.1 |
1 | ATGACTCCTG TGAGATCCTC GTCCCTGTCA CTGCTGCTTC TGCTGAGCCT GGTGGCTCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Crusted scabies is associated with increased IL-17 secretion by skin T cells. |
Effects of dietary supplementation with Laminaria hyperborea, Laminaria digitata, and Saccharomyces cerevisiae on the IL-17 pathway in the porcine colon. |
CD4+ and ??TCR+ T lymphocytes are sources of interleukin-17 in swine. |
Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC, thymus, and lung lymphocytes of young pigs. |
Cloning and characterization of Swine interleukin-17, preferentially expressed in the intestines. |