PTH1R cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	PTH1R
Entrez Gene ID	397675
Full Name	parathyroid hormone 1 receptor
Synonyms	PTH,PTHR1
Gene Type	protein-coding
Organism	Sus scrofa(pig)

mRNA and Protein(s)

mRNA	Protein	Name
NM_214382.1	NP_999547.1	parathyroid hormone/parathyroid hormone-related peptide receptor precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

KRT8, FAF1 and PTH1R gene polymorphisms are associated with leg weakness traits in pigs.
Rangkasenee N, Murani E, Brunner R, Schellander K, Cinar MU, Scholz AM, Luther H, Hofer A, Ponsuksili S, Wimmers K
Molecular biology reports40(4)2859-66(2013 Apr)

The parathyroid hormone 1 receptor directly binds to the FERM domain of ezrin, an interaction that supports apical receptor localization and signaling in LLC-PK1 cells.
Mahon MJ
Molecular endocrinology (Baltimore, Md.)23(10)1691-701(2009 Oct)

Association of parathyroid hormone-like hormone (PTHLH) and its receptor (PTHR1) with the number of functional and inverted teats in pigs.
Tetzlaff S, Chomdej S, Jonas E, Ponsuksili S, Murani E, Phatsara C, Schellander K, Wimmers K
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie126(3)237-41(2009 Jun)

PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Uenishi H, Eguchi-Ogawa T, Shinkai H, Okumura N, Suzuki K, Toki D, Hamasima N, Awata T
Nucleic acids research35(Database issue)D650-3(2007 Jan)

PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Uenishi H, Eguchi T, Suzuki K, Sawazaki T, Toki D, Shinkai H, Okumura N, Hamasima N, Awata T
Nucleic acids research32(Database issue)D484-8(2004 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study reveals clear genetic-statistical evidence for a link of KRT8, FAF1 and PTH1R with some of leg weakness related traits in pigs.
Title: KRT8, FAF1 and PTH1R gene polymorphisms are associated with leg weakness traits in pigs.

These findings reveal that direct ezrin interactions promote PTH1R apical localization and signaling in LLC-PK1 cells.
Title: The parathyroid hormone 1 receptor directly binds to the FERM domain of ezrin, an interaction that supports apical receptor localization and signaling in LLC-PK1 cells.

PTHLH and PTHR1 were evaluated as functional candidate genes for their effects on number and shape of teats in pigs
Title: Association of parathyroid hormone-like hormone (PTHLH) and its receptor (PTHR1) with the number of functional and inverted teats in pigs.

The following PTH1R gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PTH1R cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe00144	NM_214382.1 Latest version!	Sus scrofa parathyroid hormone 1 receptor (PTH1R), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PTH1R ( NM_214382.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_999547.1 Sus scrofa parathyroid hormone 1 receptor (PTH1R), mRNA.

Price & Availability↑

CloneID	OSe00144
Clone ID Related Accession (Same CDS sequence)	NM_214382.1
Accession Version	NM_214382.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Sus scrofa(pig)
Product	parathyroid hormone/parathyroid hormone-related peptide receptor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U18315.1. ##Evidence-Data-START## Transcript exon combination :: U18315.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2040923, SAMEA2041476 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCCG CCCGGATCGC GCCCGGCCTG GCGCTCCTGC TCTGCTGTCC GGTGCTCAGC 
TCGGCATACG CGCTGGTGGA TGCAGATGAC GTCATGACCA AAGAGGAGCA GATCTTCCTG 
CTGCACCGTG CCCAGGCCCA ATGTGAGAAG CGGCTCAAAG AAGTCCTGCA GAGGCCAGCT 
GACATAATGG AATCAGACAA AGGATGGGCA TCTGCGCCCA CATCAGGGAA GCCCAGGAAA 
GAGAAGGCAT CTGGGAAGCT TTATCCTGAG TCTGGGGAGG ACACTGGTAG CAGGCACCAA 
GGGCGCCCCT GCCTGCCAGA GTGGGACCAC ATCCTGTGCT GGCCGCTGGG GGCACCAGGT 
GAGGTGGTGG CCATGCCCTG TCCCGACTAC ATCTATGACT TCAATCATAA AGGCCACGCC 
TACCGACGCT GTGACCGCAA TGGCAGCTGG GAGCTGGTTC CCGGGCACAA CCGGACATGG 
GCCAACTACA GCGAGTGTGT CAAGTTCCTG ACCAATGAGA CTCGTGAACG GGAGGTGTTT 
GACCGCCTGG GCATGATCTA CACCGTGGGC TACTCCGTCT CGCTGGCCTC CCTCACCGTG 
GCTGTCCTCA TTCTGGCCTA CTTCAGGAGG CTGCACTGCA CACGCAACTA CATCCACATG 
CACTTGTTCC TGTCCTTCAT GCTGCGCGCT GTGAGCATCT TCGTCAAGGA CGCGGTGCTC 
TACTCGGGCG CCACGCTCGA TGAGGCTGAG CGCCTCACTG AGGAAGAGCT GCGCGCCATT 
GCCCAGGCAC CGCTGCCACC TGTCGCCGCC ACCAGCTACG TGGGCTGCCG GGTTGCTGTG 
ACCTTCTTCC TTTACTTCCT GGCCACCAAC TACTACTGGA TTCTGGTGGA GGGGCTGTAC 
CTGCACAGCC TCATCTTCAT GGCCTTCTTC TCCGAGAAGA AGTACCTGTG GGGCTTTACA 
GTCTTCGGCT GGGGTCTGCC TGCCATCTTC GTGGCTGTGT GGGTCAGTGT GAGAGCCACT 
CTGGCAAACA CCGGGTGCTG GGACTTGAGC TCTGGGAACA AGAAGTGGAT CATCCAGGTG 
CCCATCCTGG CCTCCATTGT GCTCAACTTC ATCCTCTTCA TCAACATTGT CCGGGTCCTT 
GCCACCAAGC TGCGGGAGAC CAACGCCGGC CGGTGTGACA CGCGGCAGCA GTACCGGAAG 
CTGCTCAAAT CCACACTGGT GCTCATGCCG CTCTTTGGCG TCCATTACAT CGTCTTCATG 
GCTACGCCAT ACACTGAGGT CTCAGGGACG CTCTGGCAAG TCCAGATGCA CTACGAGATG 
CTCTTCAACT CCTTCCAGGG ATTTTTTGTT GCCATCATAT ACTGTTTCTG CAACGGCGAG 
GTACAGGCTG AAATCAAGAA ATCCTGGAGC CGCTGGACAT TGGCACTGGA CTTTAAGCGC 
AAGGCACGTA GTGGGAGCAG CAGCTACAGC TATGGTCCGA TGGTGTCTCA CACGAGTGTG 
ACCAATGTGG GGCCCCGCAC GGGACTTGGC CTGCCCCTCA GCCCCCGCCT GCTGCCTGCC 
GCCACCACCA ATGGCCACCC CCAGCTGCCC TGCCACACCA AGCCAGAGAC CCCAGCTCTC 
CAGACCACAC CCCCTGTCGT GGCCGCTCCT AAGGACGATG GGTTCCTCAA CGGCTCCTGC 
TCAGGGTTGG ATGAGGAGGC CTCTGCACCA GAGAGGCCAT CTGTTCTGCT GCAGGAGGAG 
TGGGAGACAG TCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_999547.1
CDS	154..1911
Translation	MGAARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPADIMESDKGWASAPTSGKPRKEKASGKLYPESGEDTGSRHQGRPCLPEWDHILCWPLGAPGEVVAMPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPLPPVAATSYVGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAIFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRTGLGLPLSPRLLPAATTNGHPQLPCHTKPETPALQTTPPVVAAPKDDGFLNGSCSGLDEEASAPERPSVLLQEEWETVM

Target ORF information:

RefSeq Version	NM_214382.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa parathyroid hormone 1 receptor (PTH1R), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_214382.1

ORF Insert Sequence:

ATGGGGGCCG CCCGGATCGC GCCCGGCCTG GCGCTCCTGC TCTGCTGTCC GGTGCTCAGC 
TCGGCATACG CGCTGGTGGA TGCAGATGAC GTCATGACCA AAGAGGAGCA GATCTTCCTG 
CTGCACCGTG CCCAGGCCCA ATGTGAGAAG CGGCTCAAAG AAGTCCTGCA GAGGCCAGCT 
GACATAATGG AATCAGACAA AGGATGGGCA TCTGCGCCCA CATCAGGGAA GCCCAGGAAA 
GAGAAGGCAT CTGGGAAGCT TTATCCTGAG TCTGGGGAGG ACACTGGTAG CAGGCACCAA 
GGGCGCCCCT GCCTGCCAGA GTGGGACCAC ATCCTGTGCT GGCCGCTGGG GGCACCAGGT 
GAGGTGGTGG CCATGCCCTG TCCCGACTAC ATCTATGACT TCAATCATAA AGGCCACGCC 
TACCGACGCT GTGACCGCAA TGGCAGCTGG GAGCTGGTTC CCGGGCACAA CCGGACATGG 
GCCAACTACA GCGAGTGTGT CAAGTTCCTG ACCAATGAGA CTCGTGAACG GGAGGTGTTT 
GACCGCCTGG GCATGATCTA CACCGTGGGC TACTCCGTCT CGCTGGCCTC CCTCACCGTG 
GCTGTCCTCA TTCTGGCCTA CTTCAGGAGG CTGCACTGCA CACGCAACTA CATCCACATG 
CACTTGTTCC TGTCCTTCAT GCTGCGCGCT GTGAGCATCT TCGTCAAGGA CGCGGTGCTC 
TACTCGGGCG CCACGCTCGA TGAGGCTGAG CGCCTCACTG AGGAAGAGCT GCGCGCCATT 
GCCCAGGCAC CGCTGCCACC TGTCGCCGCC ACCAGCTACG TGGGCTGCCG GGTTGCTGTG 
ACCTTCTTCC TTTACTTCCT GGCCACCAAC TACTACTGGA TTCTGGTGGA GGGGCTGTAC 
CTGCACAGCC TCATCTTCAT GGCCTTCTTC TCCGAGAAGA AGTACCTGTG GGGCTTTACA 
GTCTTCGGCT GGGGTCTGCC TGCCATCTTC GTGGCTGTGT GGGTCAGTGT GAGAGCCACT 
CTGGCAAACA CCGGGTGCTG GGACTTGAGC TCTGGGAACA AGAAGTGGAT CATCCAGGTG 
CCCATCCTGG CCTCCATTGT GCTCAACTTC ATCCTCTTCA TCAACATTGT CCGGGTCCTT 
GCCACCAAGC TGCGGGAGAC CAACGCCGGC CGGTGTGACA CGCGGCAGCA GTACCGGAAG 
CTGCTCAAAT CCACACTGGT GCTCATGCCG CTCTTTGGCG TCCATTACAT CGTCTTCATG 
GCTACGCCAT ACACTGAGGT CTCAGGGACG CTCTGGCAAG TCCAGATGCA CTACGAGATG 
CTCTTCAACT CCTTCCAGGG ATTTTTTGTT GCCATCATAT ACTGTTTCTG CAACGGCGAG 
GTACAGGCTG AAATCAAGAA ATCCTGGAGC CGCTGGACAT TGGCACTGGA CTTTAAGCGC 
AAGGCACGTA GTGGGAGCAG CAGCTACAGC TATGGTCCGA TGGTGTCTCA CACGAGTGTG 
ACCAATGTGG GGCCCCGCAC GGGACTTGGC CTGCCCCTCA GCCCCCGCCT GCTGCCTGCC 
GCCACCACCA ATGGCCACCC CCAGCTGCCC TGCCACACCA AGCCAGAGAC CCCAGCTCTC 
CAGACCACAC CCCCTGTCGT GGCCGCTCCT AAGGACGATG GGTTCCTCAA CGGCTCCTGC 
TCAGGGTTGG ATGAGGAGGC CTCTGCACCA GAGAGGCCAT CTGTTCTGCT GCAGGAGGAG 
TGGGAGACAG TCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

KRT8, FAF1 and PTH1R gene polymorphisms are associated with leg weakness traits in pigs.
Molecular biology reports40(4)2859-66(2013 Apr)
Rangkasenee N,Murani E,Brunner R,Schellander K,Cinar MU,Scholz AM,Luther H,Hofer A,Ponsuksili S,Wimmers K

The parathyroid hormone 1 receptor directly binds to the FERM domain of ezrin, an interaction that supports apical receptor localization and signaling in LLC-PK1 cells.
Molecular endocrinology (Baltimore, Md.)23(10)1691-701(2009 Oct)
Mahon MJ

Association of parathyroid hormone-like hormone (PTHLH) and its receptor (PTHR1) with the number of functional and inverted teats in pigs.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie126(3)237-41(2009 Jun)
Tetzlaff S,Chomdej S,Jonas E,Ponsuksili S,Murani E,Phatsara C,Schellander K,Wimmers K

PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Nucleic acids research35(Database issue)D650-3(2007 Jan)
Uenishi H,Eguchi-Ogawa T,Shinkai H,Okumura N,Suzuki K,Toki D,Hamasima N,Awata T

PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Nucleic acids research32(Database issue)D484-8(2004 Jan)
Uenishi H,Eguchi T,Suzuki K,Sawazaki T,Toki D,Shinkai H,Okumura N,Hamasima N,Awata T