| Gene Symbol | IL1B |
| Entrez Gene ID | 397122 |
| Full Name | interleukin 1 beta |
| Synonyms | IL1B1 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
ORF » Species Summary » Sus scrofa » IL1B cDNA ORF clone
| Gene Symbol | IL1B |
| Entrez Gene ID | 397122 |
| Full Name | interleukin 1 beta |
| Synonyms | IL1B1 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
| mRNA | Protein | Name |
|---|---|---|
| XM_021085847.1 | XP_020941506.1 | interleukin-1 beta isoform X1 |
| NM_214055.1 | NP_999220.1 | interleukin-1 beta |
Interleukin-1? system in the oviducts of pigs during the oestrous cycle and early pregnancy.
Martyniak M, Franczak A, Kotwica G
Theriogenology9631-41(2017 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.
Title: Classical swine fever virus and p7 protein induce secretion of IL-1? in macrophages.
local expression of IL-1beta and IL-8 in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls
Title: Systemic inflammatory response and local cytokine expression in porcine models of endocarditis.
IL1B regulates expression of IL1R1 and IL1RAP and stimulates expression of PTGS1 and PTGS2 that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri-implantation period of pregnancy in pigs.
Title: Regulatory mechanism for expression of IL1B receptors in the uterine endometrium and effects of IL1B on prostaglandin synthetic enzymes during the implantation period in pigs.
the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.
Title: Interleukin-1beta regulates cell proliferation and activity of extracellular matrix remodelling enzymes in cultured primary pig heart cells.
The following IL1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe00667 | |
| Clone ID Related Accession (Same CDS sequence) | NM_214055.1 | |
| Accession Version | NM_214055.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 804bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-26 | |
| Organism | Sus scrofa(pig) | |
| Product | interleukin-1 beta | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M86725.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M86725.1, AK344440.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01048241, SAMN02904334 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCATAG TACCTGAACC CGCCAAGGAA GTGATGGCTA ACTACGGTGA CAACAATAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_999220.1 |
| CDS | 67..870 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_214055.1 |
1 | ATGGCCATAG TACCTGAACC CGCCAAGGAA GTGATGGCTA ACTACGGTGA CAACAATAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe245285 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021085847.1 | |
| Accession Version | XM_021085847.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | interleukin-1 beta isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010445.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGTCACTC ATTTTCTCCT CTTTACGCAG GTTTCTGAAG CAGCCATGGC CATAGTACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_020941506.1 |
| CDS | 323..1171 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021085847.1 |
1 | ATGGTCACTC ATTTTCTCCT CTTTACGCAG GTTTCTGAAG CAGCCATGGC CATAGTACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Interleukin-1? system in the oviducts of pigs during the oestrous cycle and early pregnancy. |