AKR1B1 cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	AKR1B1
Entrez Gene ID	396816
Full Name	aldo-keto reductase family 1 member B
Synonyms	ALR2,AR
Gene Type	protein-coding
Organism	Sus scrofa(pig)
Genome	Chromosome: 18 Map Location: 18\|18

mRNA and Protein(s)

mRNA	Protein	Name
XM_021078497.1	XP_020934156.1	aldose reductase isoform X1
NM_001001539.2	NP_001001539.1	aldo-keto reductase family 1 member B1
XM_021078498.1	XP_020934157.1	aldose reductase isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Uenishi H, Eguchi-Ogawa T, Shinkai H, Okumura N, Suzuki K, Toki D, Hamasima N, Awata T
Nucleic acids research35(Database issue)D650-3(2007 Jan)

Probing flexibility and "induced-fit" phenomena in aldose reductase by comparative crystal structure analysis and molecular dynamics simulations.
Sotriffer CA, Kr?mer O, Klebe G
Proteins56(1)52-66(2004 Jul)

PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Uenishi H, Eguchi T, Suzuki K, Sawazaki T, Toki D, Shinkai H, Okumura N, Hamasima N, Awata T
Nucleic acids research32(Database issue)D484-8(2004 Jan)

A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.
Urzhumtsev A, T?te-Favier F, Mitschler A, Barbanton J, Barth P, Urzhumtseva L, Biellmann JF, Podjarny A, Moras D
Structure (London, England : 1993)5(5)601-12(1997 May)

Location of an essential arginine residue in the primary structure of pig aldose reductase.
Kubiseski TJ, Green NC, Flynn TG
Advances in experimental medicine and biology328259-65(1993)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

crystal structure analysis and molecular dynamics simulations
Title: Probing flexibility and "induced-fit" phenomena in aldose reductase by comparative crystal structure analysis and molecular dynamics simulations.

The following AKR1B1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AKR1B1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OSe00511	NM_001001539.2 Latest version!	Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OSe241772	XM_021078497.1 Latest version!	Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
OSe241772	XM_021078498.1 Latest version!	Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AKR1B1 ( NM_001001539.2 ) cDNA ORF clone, Sus scrofa(pig) -> NP_001001539.1 Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), mRNA.

Price & Availability↑

CloneID	OSe00511
Clone ID Related Accession (Same CDS sequence)	NM_001001539.2
Accession Version	NM_001001539.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Sus scrofa(pig)
Product	aldo-keto reductase family 1 member B1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U46065.1. On Aug 31, 2012 this sequence version replaced NM_001001539.1. ##Evidence-Data-START## Transcript exon combination :: L14950.1, U46065.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1487420, SAMEA1876824 [ECO:0000348] ##Evidence-Data-END##

ATGGCCAGCC ACCTCGTGCT CTACACCGGT GCCAAGATGC CCATCTTGGG GCTGGGCACC 
TGGAAGTCCC CTCCAGGCAA AGTGACAGAG GCTGTGAAGG TGGCCATTGA CCTTGGGTAC 
CGCCACATTG ACTGTGCCCA TGTGTACCAG AACGAGAACG AGGTGGGGCT GGGCCTCCAG 
GAGAAGCTCC AAGGGCAGGT GGTGAAGCGT GAGGACCTCT TCATCGTCAG TAAGCTGTGG 
TGCACAGACC ATGAGAAGAA CCTGGTGAAA GGGGCCTGCC AGACGACCCT CCGCAACCTG 
AAGCTGGACT ACCTGGACCT CTACCTTATC CACTGGCCCA CTGGCTTCAA GCCTGGCAAG 
GACCCTTTCC CGCTGGATGG CGACGGCAAC GTGGTTCCTG ATGAGAGCGA TTTTGTGGAG 
ACGTGGGAGG CCATGGAGGA GCTGGTGGAC GAAGGGCTGG TGAAAGCCAT TGGCGTCTCC 
AACTTCAACC ATCTGCAAGT GGAGAAGATC TTAAACAAAC CTGGCCTGAA ATACAAGCCA 
GCCGTTAACC AGATCGAGGT CCACCCATAC CTCACTCAGG AGAAGTTAAT CGAATACTGC 
AAGTCCAAAG GCATCGTGGT GACTGCCTAC AGCCCCCTCG GCTCTCCCGA CAGGCCCTGG 
GCCAAGCCTG AGGACCCTTC CCTCCTGGAG GACCCCAGGA TCAAAGCGAT TGCAGCCAAG 
TACAATAAAA CCACAGCCCA GGTTCTGATC CGGTTCCCCA TGCAGAGGAA CTTGATCGTC 
ATCCCCAAGT CCGTGACGCC TGAACGCATT GCCGAGAACT TCCAGGTCTT TGACTTTGAA 
CTGAGCCCTG AGGATATGAA CACCTTACTG AGCTACAACA GGAACTGGAG GGTCTGTGCC 
TTGATGAGCT GTGCCTCCCA CAAGGATTAT CCCTTTCACG AGGAATATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001539.1
CDS	17..967
Translation	MASHLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRNLKLDYLDLYLIHWPTGFKPGKDPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALMSCASHKDYPFHEEY

Target ORF information:

RefSeq Version	NM_001001539.2
Organism	Sus scrofa(pig)
Definition	Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001539.2

ORF Insert Sequence:

ATGGCCAGCC ACCTCGTGCT CTACACCGGT GCCAAGATGC CCATCTTGGG GCTGGGCACC 
TGGAAGTCCC CTCCAGGCAA AGTGACAGAG GCTGTGAAGG TGGCCATTGA CCTTGGGTAC 
CGCCACATTG ACTGTGCCCA TGTGTACCAG AACGAGAACG AGGTGGGGCT GGGCCTCCAG 
GAGAAGCTCC AAGGGCAGGT GGTGAAGCGT GAGGACCTCT TCATCGTCAG TAAGCTGTGG 
TGCACAGACC ATGAGAAGAA CCTGGTGAAA GGGGCCTGCC AGACGACCCT CCGCAACCTG 
AAGCTGGACT ACCTGGACCT CTACCTTATC CACTGGCCCA CTGGCTTCAA GCCTGGCAAG 
GACCCTTTCC CGCTGGATGG CGACGGCAAC GTGGTTCCTG ATGAGAGCGA TTTTGTGGAG 
ACGTGGGAGG CCATGGAGGA GCTGGTGGAC GAAGGGCTGG TGAAAGCCAT TGGCGTCTCC 
AACTTCAACC ATCTGCAAGT GGAGAAGATC TTAAACAAAC CTGGCCTGAA ATACAAGCCA 
GCCGTTAACC AGATCGAGGT CCACCCATAC CTCACTCAGG AGAAGTTAAT CGAATACTGC 
AAGTCCAAAG GCATCGTGGT GACTGCCTAC AGCCCCCTCG GCTCTCCCGA CAGGCCCTGG 
GCCAAGCCTG AGGACCCTTC CCTCCTGGAG GACCCCAGGA TCAAAGCGAT TGCAGCCAAG 
TACAATAAAA CCACAGCCCA GGTTCTGATC CGGTTCCCCA TGCAGAGGAA CTTGATCGTC 
ATCCCCAAGT CCGTGACGCC TGAACGCATT GCCGAGAACT TCCAGGTCTT TGACTTTGAA 
CTGAGCCCTG AGGATATGAA CACCTTACTG AGCTACAACA GGAACTGGAG GGTCTGTGCC 
TTGATGAGCT GTGCCTCCCA CAAGGATTAT CCCTTTCACG AGGAATATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B1 ( XM_021078497.1 ) cDNA ORF clone, Sus scrofa(pig) -> XP_020934156.1 Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OSe241772
Clone ID Related Accession (Same CDS sequence)	XM_021078497.1 , XM_021078498.1
Accession Version	XM_021078497.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-12
Organism	Sus scrofa(pig)
Product	aldose reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010460.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC TGGTGGACGA AGGGCTGGTG AAAGCCATTG GCGTCTCCAA CTTCAACCAT 
CTGCAAGTGG AGAAGATCTT AAACAAACCT GGCCTGAAAT ACAAGCCAGC CGTTAACCAG 
ATCGAGGTCC ACCCATACCT CACTCAGGAG AAGTTAATCG AATACTGCAA GTCCAAAGGC 
ATCGTGGTGA CTGCCTACAG CCCCCTCGGC TCTCCCGACA GGCCCTGGGC CAAGCCTGAG 
GACCCTTCCC TCCTGGAGGA CCCCAGGATC AAAGCGATTG CAGCCAAGTA CAATAAAACC 
ACAGCCCAGG TTCTGATCCG GTTCCCCATG CAGAGGAACT TGATCGTCAT CCCCAAGTCC 
GTGACGCCTG AACGCATTGC CGAGAACTTC CAGGTCTTTG ACTTTGAACT GAGCCCTGAG 
GATATGAACA CCTTACTGAG CTACAACAGG AACTGGAGGG TCTGTGCCTT GATGAGCTGT 
GCCTCCCACA AGGATTATCC CTTTCACGAG GAATATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_020934156.1
CDS	755..1273
Translation	MEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALMSCASHKDYPFHEEY

Target ORF information:

RefSeq Version	XM_021078497.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021078497.1

ORF Insert Sequence:

ATGGAGGAGC TGGTGGACGA AGGGCTGGTG AAAGCCATTG GCGTCTCCAA CTTCAACCAT 
CTGCAAGTGG AGAAGATCTT AAACAAACCT GGCCTGAAAT ACAAGCCAGC CGTTAACCAG 
ATCGAGGTCC ACCCATACCT CACTCAGGAG AAGTTAATCG AATACTGCAA GTCCAAAGGC 
ATCGTGGTGA CTGCCTACAG CCCCCTCGGC TCTCCCGACA GGCCCTGGGC CAAGCCTGAG 
GACCCTTCCC TCCTGGAGGA CCCCAGGATC AAAGCGATTG CAGCCAAGTA CAATAAAACC 
ACAGCCCAGG TTCTGATCCG GTTCCCCATG CAGAGGAACT TGATCGTCAT CCCCAAGTCC 
GTGACGCCTG AACGCATTGC CGAGAACTTC CAGGTCTTTG ACTTTGAACT GAGCCCTGAG 
GATATGAACA CCTTACTGAG CTACAACAGG AACTGGAGGG TCTGTGCCTT GATGAGCTGT 
GCCTCCCACA AGGATTATCC CTTTCACGAG GAATATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AKR1B1 ( XM_021078498.1 ) cDNA ORF clone, Sus scrofa(pig) -> XP_020934157.1 Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OSe241772
Clone ID Related Accession (Same CDS sequence)	XM_021078497.1 , XM_021078498.1
Accession Version	XM_021078498.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-12
Organism	Sus scrofa(pig)
Product	aldose reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010460.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC TGGTGGACGA AGGGCTGGTG AAAGCCATTG GCGTCTCCAA CTTCAACCAT 
CTGCAAGTGG AGAAGATCTT AAACAAACCT GGCCTGAAAT ACAAGCCAGC CGTTAACCAG 
ATCGAGGTCC ACCCATACCT CACTCAGGAG AAGTTAATCG AATACTGCAA GTCCAAAGGC 
ATCGTGGTGA CTGCCTACAG CCCCCTCGGC TCTCCCGACA GGCCCTGGGC CAAGCCTGAG 
GACCCTTCCC TCCTGGAGGA CCCCAGGATC AAAGCGATTG CAGCCAAGTA CAATAAAACC 
ACAGCCCAGG TTCTGATCCG GTTCCCCATG CAGAGGAACT TGATCGTCAT CCCCAAGTCC 
GTGACGCCTG AACGCATTGC CGAGAACTTC CAGGTCTTTG ACTTTGAACT GAGCCCTGAG 
GATATGAACA CCTTACTGAG CTACAACAGG AACTGGAGGG TCTGTGCCTT GATGAGCTGT 
GCCTCCCACA AGGATTATCC CTTTCACGAG GAATATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_020934157.1
CDS	783..1301
Translation	MEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALMSCASHKDYPFHEEY

Target ORF information:

RefSeq Version	XM_021078498.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa aldo-keto reductase family 1 member B (AKR1B1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021078498.1

ORF Insert Sequence:

ATGGAGGAGC TGGTGGACGA AGGGCTGGTG AAAGCCATTG GCGTCTCCAA CTTCAACCAT 
CTGCAAGTGG AGAAGATCTT AAACAAACCT GGCCTGAAAT ACAAGCCAGC CGTTAACCAG 
ATCGAGGTCC ACCCATACCT CACTCAGGAG AAGTTAATCG AATACTGCAA GTCCAAAGGC 
ATCGTGGTGA CTGCCTACAG CCCCCTCGGC TCTCCCGACA GGCCCTGGGC CAAGCCTGAG 
GACCCTTCCC TCCTGGAGGA CCCCAGGATC AAAGCGATTG CAGCCAAGTA CAATAAAACC 
ACAGCCCAGG TTCTGATCCG GTTCCCCATG CAGAGGAACT TGATCGTCAT CCCCAAGTCC 
GTGACGCCTG AACGCATTGC CGAGAACTTC CAGGTCTTTG ACTTTGAACT GAGCCCTGAG 
GATATGAACA CCTTACTGAG CTACAACAGG AACTGGAGGG TCTGTGCCTT GATGAGCTGT 
GCCTCCCACA AGGATTATCC CTTTCACGAG GAATATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Nucleic acids research35(Database issue)D650-3(2007 Jan)
Uenishi H,Eguchi-Ogawa T,Shinkai H,Okumura N,Suzuki K,Toki D,Hamasima N,Awata T

Probing flexibility and "induced-fit" phenomena in aldose reductase by comparative crystal structure analysis and molecular dynamics simulations.
Proteins56(1)52-66(2004 Jul)
Sotriffer CA,Kr?mer O,Klebe G

PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Nucleic acids research32(Database issue)D484-8(2004 Jan)
Uenishi H,Eguchi T,Suzuki K,Sawazaki T,Toki D,Shinkai H,Okumura N,Hamasima N,Awata T

A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.
Structure (London, England : 1993)5(5)601-12(1997 May)
Urzhumtsev A,T?te-Favier F,Mitschler A,Barbanton J,Barth P,Urzhumtseva L,Biellmann JF,Podjarny A,Moras D

Location of an essential arginine residue in the primary structure of pig aldose reductase.
Advances in experimental medicine and biology328259-65(1993)
Kubiseski TJ,Green NC,Flynn TG

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

[email protected]

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

AKR1B1 cDNA ORF clone, Sus scrofa(pig)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム