Cabin1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cabin1
Entrez Gene ID	94165
Full Name	calcineurin binding protein 1
Synonyms	Cain
General protein information	Preferred Names calcineurin binding protein 1 Names calcineurin-binding protein cabin-1 cain calcineurin inhibitor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	physiologic inhibitor of calcineurin [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053575.2	NP_446027.2	calcineurin-binding protein cabin-1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cabin1	NP_766137.2
Homo sapiens (human)	CABIN1	NP_036427.1
Pan troglodytes (chimpanzee)	CABIN1	XP_001170637.1
Canis lupus familiaris (dog)	CABIN1	XP_005636616.1
Rattus norvegicus (Norway rat)	Cabin1	NP_446027.2
Gallus gallus (chicken)	CABIN1	XP_004934392.1
Xenopus tropicalis (tropical clawed frog)	cabin1	NP_001090709.1
Bos taurus (cattle)	CABIN1	XP_002694740.2
Danio rerio (zebrafish)	cabin1	NP_001232898.1

Gene Ontology
Bibliography

Related articles in PubMed

Upregulation of Cabin1 During Injury to Renal Tubular Epithelial Cells in Rats.
Wen Y, Li H, Zhou P, Liu L, Wang Z, Liang J
Iranian journal of kidney diseases11(6)430-437(2017 Nov)

Effect of the knockdown of Cabin1 on p53 in glomerular podocyte.
Wen Y, Zhou P, Liu L, Wang Z, Zhang Y, Liang J
Journal of receptor and signal transduction research36(2)173-80(2016)

Regulation of inflammatory responses and fibroblast-like synoviocyte apoptosis by calcineurin-binding protein 1 in mice with collagen-induced arthritis.
Yi JK, Kim HJ, Yu DH, Park SJ, Shin MJ, Yuh HS, Bae KB, Ji YR, Kim NR, Park SJ, Kim JY, Lee HS, Lee SG, Yoon du H, Hyun BH, Kim WU, Ryoo ZY
Arthritis and rheumatism64(7)2191-200(2012 Jul)

Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis.
Tagami H, Ray-Gallet D, Almouzni G, Nakatani Y
Cell116(1)51-61(2004 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In conclusion, Cabin1 expression significantly increases during podocyte injury. Knockdown of Cabin1 induces p53 expression decrease in cultured podocyte. Cabin1 may provide a new target to investigate podocyte injury.
Title: Effect of the knockdown of Cabin1 on p53 in glomerular podocyte.

The following Cabin1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cabin1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42834	NM_053575.2 Latest version!	Rattus norvegicus calcineurin binding protein 1 (Cabin1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	30	$1091.30 $1559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cabin1 ( NM_053575.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446027.2 Rattus norvegicus calcineurin binding protein 1 (Cabin1), mRNA.

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CloneID	ORa42834
Clone ID Related Accession (Same CDS sequence)	NM_053575.2
Accession Version	NM_053575.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	calcineurin-binding protein cabin-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF061947.1, AABR07044625.1, AABR07044626.1 and DV716961.1. On or before Jul 7, 2012 this sequence version replaced XM_003753457.1, XM_003753458.1, NM_053575.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF061947.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGATTCGAA TTGCAGCCTT AAATGCCAGC TCCACAATTG AAGATGACCA TGAAGGAAGC 
TTTAAAAGTC ACAAAATCCA GACAAAGGAG GCTCAGGAAG CAGAAGCCTT TGCCCTATAC 
CACAAGGCCC TGGATCTACA GAAACATGAC AGGTTTGAGG AGTCTGCCAA GGCCTACCAT 
GAACTCCTGG AGGCTCGCCT GCTGCGAGAG GCAGTTTCAT CCGGAGATGA GAAGGAAGGG 
CTGAAGCACC CTGGACTGAT ACTGAAATAT TCTACGTATA AGAACCTGGC CCAGCTGGCA 
GCCCAGCGGG AGGACCTGGA GACAGCCATG GAGTTTTATT TGGAGGCCGT GATGCTGGAT 
TCCACAGACG TCAACCTTTG GTACAAGATT GGACATGTGG CCCTGAGGCT CATCCGACTT 
CCCCTGGCTC GCCATGCTTT TGAGGAAGGG CTCCGGTGTA ATCCTGACCA CTGGCCCTGC 
TTGGACAACC TCATCACTGT TTTGTACACC CTCAGCGATT ACACAACATG TCTTTACTTC 
ATCTGCAAAG CACTGGAGAA AGACTGCCGC TACAGCAAAG GCCTGGTTCT CAAGGAGAAG 
ATTTTTGAAG AGCAACCTTG TCTCCGAAAG GACTCACTCC GAATGTTCCT CAAATGTGAC 
ATGTCAGTTC ACGAGGTGTC AGTGAATGCA GCAGAGACAC AGGCCATTGT AGACGAGGCT 
CTGGGGCTGC GGAAGAAGAG GCAGGCGTTG ATCGTGCGGG AAAAGGAGCC AGACCTGAAA 
CTAGTGCAGC CCATCCCTTT CTTCACGTGG AAGTGCCTTG GAGAGAGCTT GCTTGCCATG 
TACAATCACC TCACCACGTG TGAGCCTCCC AGGCCCAGCC TGGGCAAGAG GATTGACCTG 
TCTGACTACC AGGATCCCAG CCAGCTGCTA GCCCCCTCCG TCGTGGTTAC TCCTGTCAGT 
GTGGTCCAGC CAAGTCCTGT TTGCACCAAT CCAACTGTTG CTGTGGCCGA GCCTGTGCTC 
TCCTACACCT CTGTGACCAC AACCAGCTTC CCACTGCACA GTCCTGGCCT GCTGGACACG 
GGCACTCCTA TGGGTGATGT TTCCGGAGGA GATAAATCTA AAAAAGGGGT GAAGCGTAAG 
AAGACTTTAG AGGAAAGTGG GGAGACAGCA AAGCGGAGGT CTGCCCGTGT CCGCAACACC 
AAGTGCAAAA AAGAAGAGAA GGTGGATTTC CAGGGGCTTC TGGTAAAGTT CCTGCCGTCC 
AGGTTAAGAA AACTGGACCC TGAGGAGGAA GATGATCCAT TTAACAACTA TGAAGTTCAG 
TCAGAAGCCA AACTGGAGAG CTTCTCGAAC GTGGGACCTC ATCGACTGTC CTTCGATTCA 
GCCACATTCA TGGAATCTGA GAAGCAGGAT GTGCATGCGT TCCTGATGGA GAACCTGACC 
AATGGGGGCG TCCTGGAGCT CATGATGCGC TACCTGAAGA GCATGGGCCA CAAGTTCCTG 
CTGAAGTGGC CCCCAGGCCT GGCGGAGGTC GTACTTAGCG TCTACCACAG CTGGAGGAGG 
CACAGTACCA GCCTGCCCAA CCCATTGCTG AGGGACTGCA GCAACAAGCA CATCAAGGAC 
ATGATGCTGA TGTCTCTTTC CTGCATGGAG CTCCAACTGG ACCAGTGGCT TCTGACCAAA 
GGCAGAAGCT CCACGGTGTC TCCCCGGAAC TGCCCTGCTG GTGTGGTGAC AGGCAGGTTT 
GGGCCAGACT TCCCAGGAAC CCACTGCCTG GGTGACCTCC TGCAGCTGTC ATTTGCGTCA 
TCTCAGCGGG ATCTGTTTGA GGACGGCTGG CTGGAGTTTG TGGTCCGTGT TTACTGGCTG 
AAGGCACGTT TCTTGGCACT ACAGGGCGAT ATGGAGCAAG CTTTGGAGAA CTATGATATC 
TGCACAGAGA TACTCCAGAG CTCCACGGCT CTCCAAGCCC AGGCAGGGGC TGAGCAAAGG 
GACATTGTCA TCCGGCTGCC CAACCTGCAC AATGACTCCA TTGTTTCTCT GGAGGAAATT 
GATAAGAACC TGAAGTCTCT GGAAAGGTGC CAGTCCCTGG AGGAGATTCA GCGGCTGTTT 
GAGGCGGGCG ACTACAAGGC TGTGGTGCAG CTGCTCCGGC CCACTCTGTG CACCAGTGGC 
TTTGACCGAG CCAAACACCT GGAGTTTATG ACTTCCATTC CCGAGAGGCC GGCCCAGCTG 
CTTCTGCTGC AGGACTCTCT GCTCCGGCTG GAGGAGCACA GGCAGTGCTT TGAATGCTCT 
GACGTGGCCC TCAATGAAGC TGTCCAGCAG ATGCTGAACT CGAGTGACTC TGCGGCCAAG 
GAGGAGTGGG CGGCCACAGT GACGCAGCTG CTGCTAGGCA TGGAGCAGGC ACTGTCATCA 
GACAGCAGGG GCAGCATCCT GAAGGAGTCC TCCTCTCCCA CGGGCCTTGT CCGGCTCACC 
AACAACCTCA TTCAGGTCAT CGACTGCAGC ATGGCTGTGC AGGAGGAGCC CAAGGAGCCC 
TATGTCTCCT CCGTGCTGCC CTGGATCATC CTCCACAGGA TCATCTGGCA GGAGGAAGAC 
ACTTTCCGGT CTCTGTGCCA CCAGCAGCAG CTCCAGAACC CAACGGAAGA AGGGATCTCG 
GAGATGCCCA TGCTCCCATC TTCCCTCATG CTGCTCAACA CAGCACATGA GTACCTGGGC 
AGGAGGTCCT GGTGCTGCAA TTCAGATGGA GCGCTGCTGC GATTCTATGT GCACGTTCTC 
CAAAAGGAGC TTGCTGCGTC TGCCTCTGAG GACACTCACC CCTACAAGGA GGAGCTGGAG 
ACCGCCTTGG AGCAGTGTTT CTACTGCCTC TACAGCTTCC CCAGCAAGAA GAGCAAGGCC 
AGGTACCTGG AGGAGCACTC AGCCCAGCAG GTGGACCTCA CCTGGGAGGA CGCCCTGTTC 
ATGTTTGAGT ACTTCAAGCC CAAGACCCTC CCTGAGTTTG ACAGCTACAA GACCAGCACC 
GTCTCCGCGG ACTTGGCAAA CCTGTTGAAA AGAATCGCCA CCATTGTGCC GCGCACAGAG 
AAGCCCGCCC TGAGCATGGA CAAAGTCTCT GCCTACATTG AGGGAACCTC AGCGGAGGTG 
CCCTGCCTTC CTGACGGGGC AGACCCCGCC CCTCCAGTGC TGAATGAGCT CTACTACCTC 
CTGGCTGACT ATCACTTCAA AAACAAAGAG CAGTCCAAAG CCATCAAGTT CTACATGCAT 
GACATTTGCA TCTGCCCTAA CAGGTTTGAT TCCTGGGCAG GCATGGCTCT GGCCCGGGCC 
AGCCGAATTC AGGACAAGCT GAACTCAAAT GAGCTGAAGA GTGATGGACC CATCTGGAGA 
CATGCCACAC CTGTTCTGAA CTGCTTCCGG AGGGCCCTTG AGATTGACAG CTCTAACTTG 
TCCTTGTGGA TTGAGTATGG CACCATGTCC TATGCCTTGC ACTCATTCGC GTCCCGTCAG 
CTGAAGCAGT GGCGAGCCGA GCTGCCTCCT GAGGTTGTGC AGCAGATGGA GGATCGGCGA 
GACAGCATGC TGGAGACAGC CAGGCACTGT TTCACGTCTG CAGCCCACTG CGAGGGTGAT 
GGCGATGAGG AGGAGTGGCT CATTCACTAC ATGCTGGGCA AAGTGGCCGA GAAGCAGCAG 
CAGCCGCCGA CCGTGTACCT GCTGCACTAC CGCCAGGCGG GCCACTACTT ACACGAGGAG 
GCCGCCCGCT ACCCTAAGAA GATTCACTAC CACAACCCGC CCGAGCTGGC CATGGAAGCC 
CTGGAGGTGT ACTTCCGGCT CCATGCGTCC ATCCTGAAGC TCCTGGGCAA ACCTGACTCT 
GGGGTTAGCG CAGAGGTCCT GGTCAGCTTT ATGAAGGAAG CAGCAGAAGG ACCTTTTGCC 
AGGGGCGAGG AGAAGAATAC ACCTAAAGCT TCAGAAAAGG AGAAGGCCTG CCTGGTGGAT 
GAGGACTCCC ACTCTTCAGC TGGGACACTG CCGGGCCCCG GAGCCTCCCT TCCCTCCTCC 
TCTGGCCCAG GTCTGACATC CCCACCTTAC ACAGCCACTC CGATTGACCA CGATTACGTC 
AAATGTAAAA AACCCCGTCA GCAGGCGACG CCGGACGACC GAAGCCAGGA CAGCACAGCT 
GTGGCACTGT CAGACTCCAG CTCAACACAG GACTTCTTTA ATGAGCCCAC AAGTTTGCTG 
GACGGTTCTC GAAAGCTCCT TCCAGAGAAG AGGATCTCTG GGCTCAGTGC TCAAGCAGGA 
CCAAGTGGTA AAGACCTTCC AGGGCCCACA GAGGAAAGAG GAAAAACGGA GGAGTCTTTG 
GAGAGCACAG AGGCCTTCCG GGTTGTAGAA CCAAGCGTCC AGAAGCCTGT GGCAGATTCC 
TCGGCCTCTG CTTACATCCC CAGCAAGCCC GCAGTGTCCA CGCCCCCTCC GTGGGATGGG 
AAGAAGAGGA GTGACCCCCT AGGGGAGCCA GTGGCTTTCC CTCAGGGGCT GCCAGCAGGT 
GCTGAGGAAC AGCGCCAGTT CCTCACAGAG CAGTGCATCG CCTCCTTCTG CCTGTGCTTG 
AGTCGCTTCC CACAGCACTA CAAGAGTCTC TACCGGCTGG CCTTTCTCTA CACCTACAGC 
AAGACTCACC GGAACCTCCA GTGGGCCCGT GATGTGTTGC TAGGCAGCAG TATCCCATGG 
CAACAACTGC AGCACATGCC GGCACAGGGG CTCTTCTGCG AGAGGAACAA GACCAATTTC 
TTCAACGGCA TCTGGCGGAT CCCCGTGGAT GAGATTGACC GGCCCGGCAG CTTCGCCTGG 
CACATGAACC GCTCCATCGT GCTGCTACTC AAGGTTCTAG CCCAGCTCCG GGACCACAGC 
ACCCTGTTGA AGGTGTCCTC CATGCTGCAG CGGACACCAG ACCAGGGCAA GAAATATCTG 
CGAGATGCTG ACCGCCAGGT GCTGGCACAG CGCGCCTTCA TCCTCACTGT GAAGGTGCTG 
GAGGACACAC TGAGTGAGCT TGCAGAGGGG TTAGAGCACC CAGGATCCAA GGCCTGTGGC 
CTCTCTGGAG CCAGGATGAC CACCGATGTC TCACACAAAG CCAGTCCCGA GGATGGCCAG 
GAAAGCCTCC CACACCCCAA GAAGCTACCT CTAGCTGATG GCTCAGGACC AGGGCCTGAG 
CCAGGGGGCA AAGTGGGCCC TCTCCACCAA TTGCCAGTGG CCACAGACAC AAGGGACAAC 
ACAGAGCAGG GTGGGGAGCC GAAAGACAAA GAGCGTCCCC CGGTGGGGCC CACAGAACCC 
ATGGACACCG GCGAGACTGC TGCTCGCCAC CCAGACTTGG AACCGACGCC ACGTCTGTTG 
CCAGGCCGCC CCCCAAGGGA CCGGGGTCCC GAGAGCCGCT CTGCTGAGCT TTCCCTGGAG 
GAGCTGAGCA TCAGCACCCG GCAGCAGCCT GCCCCACTTG TACCATCCCC AGTAACCCCC 
ACCACAGCTG CTCCCACTAC CATGGGGGCC AGGGCAGCGG GGCACCCCGA GGAGGCACCG 
CCAAGGCCTA ATCGAAAGAG GAAACTCCTG CAGGACACAG AGTCTGGCAA GACGCTCCTT 
TTGGACGCCT ACCGTGTGTG GCAGCAGGGC CAGAAGGCCA TGGCCTATGA CCTGAGCCGC 
ATCGAGAAGA TCATGTCGGA GACTTACATG CTCATCAAGC AGGTGGACGA GGAGACTGCA 
CTGGAGCAGG CTGTGAAGTT CTGTCAGGTC CACCTCGGGG CTGCTGCCCA GAGACAGGCC 
TCAGGAGATG CACCCACTAC CCCCAAGCAC CCCAAGGACA GCCGAGAGAA TTTCTTCCCT 
GCAACAGTGG CCCCCTCAGC ACCTGACACC ACAGCACCTG ACGCTCTCCA GCGGCCCAGT 
GACTCCCACC TCAAGCCTGG GTTGGCTGCT GCCATCACCT GCCCTCCCTC AGCATCAGCC 
TCTACCCCAG ACCCTGGAAT TCCCCAGCCA CACAGGCCAG AGGCTGTGCC CAGCAGGGCC 
CCTCTGAGTC CTGATGGAGA AGAGGTGTCA GGAGTGACAG AGGGTCCCAG CTTTCTATCC 
CAAGAACCAC GGCACAGTCA CCAGATGAAA ATGGCTGCCA CTGGTCCCCT GGCCGAGCAG 
CACTGCTGGC CAGTGGAGGC TGCTTGCCAG ACAGGTGCCG AGCCCACCTT CAGCCAAGCC 
ACCAGCACCA AGGTCCCCAG CAGTGGAAGT ACCCAGACAC CTGAGAGCCA TCAAGGCAAA 
ACTGAGTCCA GCAGAGCCAA GTCCCGCCTC CTGCCCAACA TGCCAAAGCT GGTGATCCCC 
TCGGCCACCA CCAAGTTCCC CCCTGAGATC ACCGTCACAC CACCTACCCC CACCCTGCTC 
TCCCCCAAAG GCAGCATCTC AGAGGAGACC AAGCAGAAGC TGAAGTCTGC CATCCTGTCT 
GCCCAATCTG CCGCCAATGT GAGGAAGGAG AGCCTGTGCC AGCCAGCCCT GGAGGTTCTG 
GAGACATCCA GCCAGGAGTC CTCATTGGAG AGTGAGACAG ACGAGGACGA TGACTTTATG 
GACGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446027.2
CDS	326..6874
Translation	MIRIAALNASSTIEDDHEGSFKSHKIQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSVHEVSVNAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQLLAPSVVVTPVSVVQPSPVCTNPTVAVAEPVLSYTSVTTTSFPLHSPGLLDTGTPMGDVSGGDKSKKGVKRKKTLEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQSEAKLESFSNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGVLELMMRYLKSMGHKFLLKWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSTVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEILQSSTALQAQAGAEQRDIVIRLPNLHNDSIVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVQLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLEEHRQCFECSDVALNEAVQQMLNSSDSAAKEEWAATVTQLLLGMEQALSSDSRGSILKESSSPTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGISEMPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVHVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLTWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEVPCLPDGADPAPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWRHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRAELPPEVVQQMEDRRDSMLETARHCFTSAAHCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVSAEVLVSFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPRQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLDGSRKLLPEKRISGLSAQAGPSGKDLPGPTEERGKTEESLESTEAFRVVEPSVQKPVADSSASAYIPSKPAVSTPPPWDGKKRSDPLGEPVAFPQGLPAGAEEQRQFLTEQCIASFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGLEHPGSKACGLSGARMTTDVSHKASPEDGQESLPHPKKLPLADGSGPGPEPGGKVGPLHQLPVATDTRDNTEQGGEPKDKERPPVGPTEPMDTGETAARHPDLEPTPRLLPGRPPRDRGPESRSAELSLEELSISTRQQPAPLVPSPVTPTTAAPTTMGARAAGHPEEAPPRPNRKRKLLQDTESGKTLLLDAYRVWQQGQKAMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAAAQRQASGDAPTTPKHPKDSRENFFPATVAPSAPDTTAPDALQRPSDSHLKPGLAAAITCPPSASASTPDPGIPQPHRPEAVPSRAPLSPDGEEVSGVTEGPSFLSQEPRHSHQMKMAATGPLAEQHCWPVEAACQTGAEPTFSQATSTKVPSSGSTQTPESHQGKTESSRAKSRLLPNMPKLVIPSATTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV

Target ORF information:

RefSeq Version	NM_053575.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcineurin binding protein 1 (Cabin1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053575.2

ORF Insert Sequence:

ATGATTCGAA TTGCAGCCTT AAATGCCAGC TCCACAATTG AAGATGACCA TGAAGGAAGC 
TTTAAAAGTC ACAAAATCCA GACAAAGGAG GCTCAGGAAG CAGAAGCCTT TGCCCTATAC 
CACAAGGCCC TGGATCTACA GAAACATGAC AGGTTTGAGG AGTCTGCCAA GGCCTACCAT 
GAACTCCTGG AGGCTCGCCT GCTGCGAGAG GCAGTTTCAT CCGGAGATGA GAAGGAAGGG 
CTGAAGCACC CTGGACTGAT ACTGAAATAT TCTACGTATA AGAACCTGGC CCAGCTGGCA 
GCCCAGCGGG AGGACCTGGA GACAGCCATG GAGTTTTATT TGGAGGCCGT GATGCTGGAT 
TCCACAGACG TCAACCTTTG GTACAAGATT GGACATGTGG CCCTGAGGCT CATCCGACTT 
CCCCTGGCTC GCCATGCTTT TGAGGAAGGG CTCCGGTGTA ATCCTGACCA CTGGCCCTGC 
TTGGACAACC TCATCACTGT TTTGTACACC CTCAGCGATT ACACAACATG TCTTTACTTC 
ATCTGCAAAG CACTGGAGAA AGACTGCCGC TACAGCAAAG GCCTGGTTCT CAAGGAGAAG 
ATTTTTGAAG AGCAACCTTG TCTCCGAAAG GACTCACTCC GAATGTTCCT CAAATGTGAC 
ATGTCAGTTC ACGAGGTGTC AGTGAATGCA GCAGAGACAC AGGCCATTGT AGACGAGGCT 
CTGGGGCTGC GGAAGAAGAG GCAGGCGTTG ATCGTGCGGG AAAAGGAGCC AGACCTGAAA 
CTAGTGCAGC CCATCCCTTT CTTCACGTGG AAGTGCCTTG GAGAGAGCTT GCTTGCCATG 
TACAATCACC TCACCACGTG TGAGCCTCCC AGGCCCAGCC TGGGCAAGAG GATTGACCTG 
TCTGACTACC AGGATCCCAG CCAGCTGCTA GCCCCCTCCG TCGTGGTTAC TCCTGTCAGT 
GTGGTCCAGC CAAGTCCTGT TTGCACCAAT CCAACTGTTG CTGTGGCCGA GCCTGTGCTC 
TCCTACACCT CTGTGACCAC AACCAGCTTC CCACTGCACA GTCCTGGCCT GCTGGACACG 
GGCACTCCTA TGGGTGATGT TTCCGGAGGA GATAAATCTA AAAAAGGGGT GAAGCGTAAG 
AAGACTTTAG AGGAAAGTGG GGAGACAGCA AAGCGGAGGT CTGCCCGTGT CCGCAACACC 
AAGTGCAAAA AAGAAGAGAA GGTGGATTTC CAGGGGCTTC TGGTAAAGTT CCTGCCGTCC 
AGGTTAAGAA AACTGGACCC TGAGGAGGAA GATGATCCAT TTAACAACTA TGAAGTTCAG 
TCAGAAGCCA AACTGGAGAG CTTCTCGAAC GTGGGACCTC ATCGACTGTC CTTCGATTCA 
GCCACATTCA TGGAATCTGA GAAGCAGGAT GTGCATGCGT TCCTGATGGA GAACCTGACC 
AATGGGGGCG TCCTGGAGCT CATGATGCGC TACCTGAAGA GCATGGGCCA CAAGTTCCTG 
CTGAAGTGGC CCCCAGGCCT GGCGGAGGTC GTACTTAGCG TCTACCACAG CTGGAGGAGG 
CACAGTACCA GCCTGCCCAA CCCATTGCTG AGGGACTGCA GCAACAAGCA CATCAAGGAC 
ATGATGCTGA TGTCTCTTTC CTGCATGGAG CTCCAACTGG ACCAGTGGCT TCTGACCAAA 
GGCAGAAGCT CCACGGTGTC TCCCCGGAAC TGCCCTGCTG GTGTGGTGAC AGGCAGGTTT 
GGGCCAGACT TCCCAGGAAC CCACTGCCTG GGTGACCTCC TGCAGCTGTC ATTTGCGTCA 
TCTCAGCGGG ATCTGTTTGA GGACGGCTGG CTGGAGTTTG TGGTCCGTGT TTACTGGCTG 
AAGGCACGTT TCTTGGCACT ACAGGGCGAT ATGGAGCAAG CTTTGGAGAA CTATGATATC 
TGCACAGAGA TACTCCAGAG CTCCACGGCT CTCCAAGCCC AGGCAGGGGC TGAGCAAAGG 
GACATTGTCA TCCGGCTGCC CAACCTGCAC AATGACTCCA TTGTTTCTCT GGAGGAAATT 
GATAAGAACC TGAAGTCTCT GGAAAGGTGC CAGTCCCTGG AGGAGATTCA GCGGCTGTTT 
GAGGCGGGCG ACTACAAGGC TGTGGTGCAG CTGCTCCGGC CCACTCTGTG CACCAGTGGC 
TTTGACCGAG CCAAACACCT GGAGTTTATG ACTTCCATTC CCGAGAGGCC GGCCCAGCTG 
CTTCTGCTGC AGGACTCTCT GCTCCGGCTG GAGGAGCACA GGCAGTGCTT TGAATGCTCT 
GACGTGGCCC TCAATGAAGC TGTCCAGCAG ATGCTGAACT CGAGTGACTC TGCGGCCAAG 
GAGGAGTGGG CGGCCACAGT GACGCAGCTG CTGCTAGGCA TGGAGCAGGC ACTGTCATCA 
GACAGCAGGG GCAGCATCCT GAAGGAGTCC TCCTCTCCCA CGGGCCTTGT CCGGCTCACC 
AACAACCTCA TTCAGGTCAT CGACTGCAGC ATGGCTGTGC AGGAGGAGCC CAAGGAGCCC 
TATGTCTCCT CCGTGCTGCC CTGGATCATC CTCCACAGGA TCATCTGGCA GGAGGAAGAC 
ACTTTCCGGT CTCTGTGCCA CCAGCAGCAG CTCCAGAACC CAACGGAAGA AGGGATCTCG 
GAGATGCCCA TGCTCCCATC TTCCCTCATG CTGCTCAACA CAGCACATGA GTACCTGGGC 
AGGAGGTCCT GGTGCTGCAA TTCAGATGGA GCGCTGCTGC GATTCTATGT GCACGTTCTC 
CAAAAGGAGC TTGCTGCGTC TGCCTCTGAG GACACTCACC CCTACAAGGA GGAGCTGGAG 
ACCGCCTTGG AGCAGTGTTT CTACTGCCTC TACAGCTTCC CCAGCAAGAA GAGCAAGGCC 
AGGTACCTGG AGGAGCACTC AGCCCAGCAG GTGGACCTCA CCTGGGAGGA CGCCCTGTTC 
ATGTTTGAGT ACTTCAAGCC CAAGACCCTC CCTGAGTTTG ACAGCTACAA GACCAGCACC 
GTCTCCGCGG ACTTGGCAAA CCTGTTGAAA AGAATCGCCA CCATTGTGCC GCGCACAGAG 
AAGCCCGCCC TGAGCATGGA CAAAGTCTCT GCCTACATTG AGGGAACCTC AGCGGAGGTG 
CCCTGCCTTC CTGACGGGGC AGACCCCGCC CCTCCAGTGC TGAATGAGCT CTACTACCTC 
CTGGCTGACT ATCACTTCAA AAACAAAGAG CAGTCCAAAG CCATCAAGTT CTACATGCAT 
GACATTTGCA TCTGCCCTAA CAGGTTTGAT TCCTGGGCAG GCATGGCTCT GGCCCGGGCC 
AGCCGAATTC AGGACAAGCT GAACTCAAAT GAGCTGAAGA GTGATGGACC CATCTGGAGA 
CATGCCACAC CTGTTCTGAA CTGCTTCCGG AGGGCCCTTG AGATTGACAG CTCTAACTTG 
TCCTTGTGGA TTGAGTATGG CACCATGTCC TATGCCTTGC ACTCATTCGC GTCCCGTCAG 
CTGAAGCAGT GGCGAGCCGA GCTGCCTCCT GAGGTTGTGC AGCAGATGGA GGATCGGCGA 
GACAGCATGC TGGAGACAGC CAGGCACTGT TTCACGTCTG CAGCCCACTG CGAGGGTGAT 
GGCGATGAGG AGGAGTGGCT CATTCACTAC ATGCTGGGCA AAGTGGCCGA GAAGCAGCAG 
CAGCCGCCGA CCGTGTACCT GCTGCACTAC CGCCAGGCGG GCCACTACTT ACACGAGGAG 
GCCGCCCGCT ACCCTAAGAA GATTCACTAC CACAACCCGC CCGAGCTGGC CATGGAAGCC 
CTGGAGGTGT ACTTCCGGCT CCATGCGTCC ATCCTGAAGC TCCTGGGCAA ACCTGACTCT 
GGGGTTAGCG CAGAGGTCCT GGTCAGCTTT ATGAAGGAAG CAGCAGAAGG ACCTTTTGCC 
AGGGGCGAGG AGAAGAATAC ACCTAAAGCT TCAGAAAAGG AGAAGGCCTG CCTGGTGGAT 
GAGGACTCCC ACTCTTCAGC TGGGACACTG CCGGGCCCCG GAGCCTCCCT TCCCTCCTCC 
TCTGGCCCAG GTCTGACATC CCCACCTTAC ACAGCCACTC CGATTGACCA CGATTACGTC 
AAATGTAAAA AACCCCGTCA GCAGGCGACG CCGGACGACC GAAGCCAGGA CAGCACAGCT 
GTGGCACTGT CAGACTCCAG CTCAACACAG GACTTCTTTA ATGAGCCCAC AAGTTTGCTG 
GACGGTTCTC GAAAGCTCCT TCCAGAGAAG AGGATCTCTG GGCTCAGTGC TCAAGCAGGA 
CCAAGTGGTA AAGACCTTCC AGGGCCCACA GAGGAAAGAG GAAAAACGGA GGAGTCTTTG 
GAGAGCACAG AGGCCTTCCG GGTTGTAGAA CCAAGCGTCC AGAAGCCTGT GGCAGATTCC 
TCGGCCTCTG CTTACATCCC CAGCAAGCCC GCAGTGTCCA CGCCCCCTCC GTGGGATGGG 
AAGAAGAGGA GTGACCCCCT AGGGGAGCCA GTGGCTTTCC CTCAGGGGCT GCCAGCAGGT 
GCTGAGGAAC AGCGCCAGTT CCTCACAGAG CAGTGCATCG CCTCCTTCTG CCTGTGCTTG 
AGTCGCTTCC CACAGCACTA CAAGAGTCTC TACCGGCTGG CCTTTCTCTA CACCTACAGC 
AAGACTCACC GGAACCTCCA GTGGGCCCGT GATGTGTTGC TAGGCAGCAG TATCCCATGG 
CAACAACTGC AGCACATGCC GGCACAGGGG CTCTTCTGCG AGAGGAACAA GACCAATTTC 
TTCAACGGCA TCTGGCGGAT CCCCGTGGAT GAGATTGACC GGCCCGGCAG CTTCGCCTGG 
CACATGAACC GCTCCATCGT GCTGCTACTC AAGGTTCTAG CCCAGCTCCG GGACCACAGC 
ACCCTGTTGA AGGTGTCCTC CATGCTGCAG CGGACACCAG ACCAGGGCAA GAAATATCTG 
CGAGATGCTG ACCGCCAGGT GCTGGCACAG CGCGCCTTCA TCCTCACTGT GAAGGTGCTG 
GAGGACACAC TGAGTGAGCT TGCAGAGGGG TTAGAGCACC CAGGATCCAA GGCCTGTGGC 
CTCTCTGGAG CCAGGATGAC CACCGATGTC TCACACAAAG CCAGTCCCGA GGATGGCCAG 
GAAAGCCTCC CACACCCCAA GAAGCTACCT CTAGCTGATG GCTCAGGACC AGGGCCTGAG 
CCAGGGGGCA AAGTGGGCCC TCTCCACCAA TTGCCAGTGG CCACAGACAC AAGGGACAAC 
ACAGAGCAGG GTGGGGAGCC GAAAGACAAA GAGCGTCCCC CGGTGGGGCC CACAGAACCC 
ATGGACACCG GCGAGACTGC TGCTCGCCAC CCAGACTTGG AACCGACGCC ACGTCTGTTG 
CCAGGCCGCC CCCCAAGGGA CCGGGGTCCC GAGAGCCGCT CTGCTGAGCT TTCCCTGGAG 
GAGCTGAGCA TCAGCACCCG GCAGCAGCCT GCCCCACTTG TACCATCCCC AGTAACCCCC 
ACCACAGCTG CTCCCACTAC CATGGGGGCC AGGGCAGCGG GGCACCCCGA GGAGGCACCG 
CCAAGGCCTA ATCGAAAGAG GAAACTCCTG CAGGACACAG AGTCTGGCAA GACGCTCCTT 
TTGGACGCCT ACCGTGTGTG GCAGCAGGGC CAGAAGGCCA TGGCCTATGA CCTGAGCCGC 
ATCGAGAAGA TCATGTCGGA GACTTACATG CTCATCAAGC AGGTGGACGA GGAGACTGCA 
CTGGAGCAGG CTGTGAAGTT CTGTCAGGTC CACCTCGGGG CTGCTGCCCA GAGACAGGCC 
TCAGGAGATG CACCCACTAC CCCCAAGCAC CCCAAGGACA GCCGAGAGAA TTTCTTCCCT 
GCAACAGTGG CCCCCTCAGC ACCTGACACC ACAGCACCTG ACGCTCTCCA GCGGCCCAGT 
GACTCCCACC TCAAGCCTGG GTTGGCTGCT GCCATCACCT GCCCTCCCTC AGCATCAGCC 
TCTACCCCAG ACCCTGGAAT TCCCCAGCCA CACAGGCCAG AGGCTGTGCC CAGCAGGGCC 
CCTCTGAGTC CTGATGGAGA AGAGGTGTCA GGAGTGACAG AGGGTCCCAG CTTTCTATCC 
CAAGAACCAC GGCACAGTCA CCAGATGAAA ATGGCTGCCA CTGGTCCCCT GGCCGAGCAG 
CACTGCTGGC CAGTGGAGGC TGCTTGCCAG ACAGGTGCCG AGCCCACCTT CAGCCAAGCC 
ACCAGCACCA AGGTCCCCAG CAGTGGAAGT ACCCAGACAC CTGAGAGCCA TCAAGGCAAA 
ACTGAGTCCA GCAGAGCCAA GTCCCGCCTC CTGCCCAACA TGCCAAAGCT GGTGATCCCC 
TCGGCCACCA CCAAGTTCCC CCCTGAGATC ACCGTCACAC CACCTACCCC CACCCTGCTC 
TCCCCCAAAG GCAGCATCTC AGAGGAGACC AAGCAGAAGC TGAAGTCTGC CATCCTGTCT 
GCCCAATCTG CCGCCAATGT GAGGAAGGAG AGCCTGTGCC AGCCAGCCCT GGAGGTTCTG 
GAGACATCCA GCCAGGAGTC CTCATTGGAG AGTGAGACAG ACGAGGACGA TGACTTTATG 
GACGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Upregulation of Cabin1 During Injury to Renal Tubular Epithelial Cells in Rats.
ian journal of kidney diseases11(6)430-437(2017 Nov)
Wen Y,Li H,Zhou P,Liu L,Wang Z,Liang J

Effect of the knockdown of Cabin1 on p53 in glomerular podocyte.
Journal of receptor and signal transduction research36(2)173-80(2016)
Wen Y,Zhou P,Liu L,Wang Z,Zhang Y,Liang J

Regulation of inflammatory responses and fibroblast-like synoviocyte apoptosis by calcineurin-binding protein 1 in mice with collagen-induced arthritis.
Arthritis and rheumatism64(7)2191-200(2012 Jul)
Yi JK,Kim HJ,Yu DH,Park SJ,Shin MJ,Yuh HS,Bae KB,Ji YR,Kim NR,Park SJ,Kim JY,Lee HS,Lee SG,Yoon du H,Hyun BH,Kim WU,Ryoo ZY

Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis.
Cell116(1)51-61(2004 Jan)
Tagami H,Ray-Gallet D,Almouzni G,Nakatani Y