Cdhr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdhr1
Entrez Gene ID	93662
Full Name	cadherin-related family member 1
Synonyms	Pcdh21
General protein information	Preferred Names cadherin-related family member 1 Names cadherin-related family member 1 MT-protocadherin photoreceptor cadherin prCAD protocadherin-21
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16p14
Summary	non-classical cadherin gene which maybe involved in the formation and maintenance of neuronal network in the brain [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053572.1	NP_446024.1	cadherin-related family member 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CDHR1	NP_149091.1
Mus musculus (house mouse)	Cdhr1	NP_570948.1
	CDHR1	XP_001086534.2
Bos taurus (cattle)	CDHR1	NP_777248.1
Danio rerio (zebrafish)	cdhr1a	NP_001005402.1
Canis lupus familiaris (dog)	CDHR1	XP_853425.2
Rattus norvegicus (Norway rat)	Cdhr1	NP_446024.1
Xenopus tropicalis (tropical clawed frog)	cdhr1	XP_002933948.2
Pan troglodytes (chimpanzee)	CDHR1	XP_001154192.2
Gallus gallus (chicken)	CDHR1	NP_001001759.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of a novel mutation in the CDHR1 gene in a family with recessive retinal degeneration.
Duncan JL, Roorda A, Navani M, Vishweswaraiah S, Syed R, Soudry S, Ratnam K, Gudiseva HV, Lee P, Gaasterland T, Ayyagari R
Archives of ophthalmology (Chicago, Ill. : 1960)130(10)1301-8(2012 Oct)

Mutations in PCDH21 cause autosomal recessive cone-rod dystrophy.
Ostergaard E, Batbayli M, Duno M, Vilhelmsen K, Rosenberg T
Journal of medical genetics47(10)665-9(2010 Oct)

Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.
Yang Z, Chen Y, Lillo C, Chien J, Yu Z, Michaelides M, Klein M, Howes KA, Li Y, Kaminoh Y, Chen H, Zhao C, Chen Y, Al-Sheikh YT, Karan G, Corbeil D, Escher P, Kamaya S, Li C, Johnson S, Frederick JM, Zhao Y, Wang C, Cameron DJ, Huttner WB, Schorderet DF, Munier FL, Moore AT, Birch DG, Baehr W, Hunt DM, Williams DS, Zhang K
The Journal of clinical investigation118(8)2908-16(2008 Aug)

A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival.
Rattner A, Smallwood PM, Williams J, Cooke C, Savchenko A, Lyubarsky A, Pugh EN, Nathans J
Neuron32(5)775-86(2001 Dec)

Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.
Nakajima D, Nakayama M, Kikuno R, Hirosawa M, Nagase T, Ohara O
Brain research. Molecular brain research94(1-2)85-95(2001 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cdhr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdhr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09929	NM_053572.1 Latest version!	Rattus norvegicus cadherin-related family member 1 (Cdhr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$503.30 $719.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdhr1 ( NM_053572.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446024.1 Rattus norvegicus cadherin-related family member 1 (Cdhr1), mRNA.

Price & Availability↑

CloneID	ORa09929
Clone ID Related Accession (Same CDS sequence)	NM_053572.1
Accession Version	NM_053572.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2580bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	cadherin-related family member 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB053449.1. On Jan 12, 2005 this sequence version replaced XM_346480.1. ##Evidence-Data-START## Transcript exon combination :: AB053449.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END##

ATGAGGCGTG GCCCACAGGT TGCCCTGGTC CTGGGGCTGC TGTGCATTTA CCTAGCCCAG 
GCCAACTTTG CCCCTCACTT CTTTGACAAT GGAGTGGGCA GCACCAACGG AAACATGGCC 
CTGTTCAGCC TCCCAGAAGA CACTCCTGTA GGTTCTCATG TGTACACACT AAATGGGACT 
GACCCCGAGG GAGACCCTAT CTCCTACCAT ATCAGCTTTG ACCCCAGCAC TAGAAGTGTC 
TTTTCTGTTG ACCCCAATTT TGGAAACATC ACCCTGGTGG AAGAGCTGGA CAGAGAGAGA 
GAGGATGAGA TAGAAGCCAT CATCAGCATC TCCGACGGCC TGAACCTGGT GGCAGAGAAA 
GTTGTGATAG TGGTGACAGA TGCCAATGAT GAAGCACCCA GGTTCCTCCA GGAGCCTTAC 
AACATCCTGG TTCCAGAGAA CACACCTGCT GGGAGCAGCA TCTTTAAGGT ACAGGCAGAG 
GACAAGGACA CAGGCTCTGG AGGCAGTGTC ACCTACTTCC TTCAGAGCCT ACACTCCTCC 
AAGTTCACCG TAGACCGTCA CAGCGGGGTG CTGCGACTCC AGGCTGGGGC CACACTGGAC 
TATGAGAAGT CGAGGGCTCA TTTCATCACT GTGGTTGCCA AGGATGGTGG GGGCAGGCTT 
CGAGGAGCTG ATGTGGTATT CTCAGCCACC ACGACTGTCA CCATCAATGT GGAAGATGTT 
CAGGACACAG CCCCTATATT CGTGGGTACA CCCTACTATG GTTATGTGTA CGAAGACACC 
CTTCCGGGCT CAGAGGTGCT GACGGTGGTT GCCATAGATG GAGACCGAGG CAAACCCAAC 
CACATCCTCT ATAGGCTCTT GAATGAGAGT GATGGACTCT TTGAAATTAA TGAGACATCT 
GGAGCCATCT CCGTCCTTCA GAGCCCTGCC CAGCTCCGAA GAGAGGTGTA TGAGCTTCAT 
GTACAGGTGA CAGAGGTCAA CTCTTCAGGA AGCCCAGCTG CTCAGTCCAC AGTCCCAGTG 
ATCATCAGGA TCGTGGACCT CAACAACCAC CCTCCAACCT TCTATGGAGA GAGCGGGCCC 
CAGAACAAGT TTGAACTATC TATGTTTGAG CACCCGCCCC AGGGGGAAAT CCTCCGTGGA 
CTCAAGATCA CTGTCAATGA CTCTGACCAG GGAGCCAATG CCAAATTCAA CTTACGGCTG 
GTGGGACCTG GAGGCATCTT TCGAGTGGTG CCACAGACAG TCCTGAATGA AGCCCAAGTG 
ACCATCATAG TGGAAAACTC AGCTGCCATT GACTTTGAAA AGTCTAAGTC GTTAACCTTC 
AAGCTCCTGG CCATTGAAGT GAACACCCCG GAGAAGTTCA GCTCCACAGC AGACATTGTG 
ATCCAGCTTC TGGACACCAA TGATAATGTT CCCAAGTTCA CCTCTCACTA CTACATCGCC 
AGGATCCCAG AGAATGTTCC AGGGGGCTCC AATGTGGTGG CTGTCACAGC TGTGGATCCA 
GATACAGGAC CATGGGGCAA AGTCCAGTAT TCCATTTATG GGACCGGATC AGACCTCTTC 
TTGATTCACC CATCCACTGG GCTTATCTAC ACTCAGCCCT GGGCCAGCCT GGATGCTGAG 
GGCACTTCGA GGTACAACTT TTATGTGAAG GCAGAAGACA TGGATGGGAG GTACAGCCTG 
GCTGAGGTGT TTGTCACTCT GTTGGATGTC AATGACCACT ACCCCCAGTT TGTACAGAGT 
GTCCAGGAGA AGACGATGGT GCTGGGGACC CCACTGAAAA TTGAGGCCAC AGACCAGGAT 
GCAGAGGAAC CAAACAACTT GGTCGACTAC TCCATTACCC GTGCAGAGCC AGTCAACGTG 
TTTGACATAG ATGCACACAC AGGGGAGATC AGGCTCAAGA ATTCCATCCG CTCCTTGGAG 
GCCCTACACA ACATTACACC CAGCGGGGAA TACTCATGGT CCCTACAGGT GCAGGCCAAG 
GACCGAGGAT CTCCATCTTT CAGCACAACA GCCTTACTCA AGATCGACAT CACAGACACA 
GAGAGGCTGT CCAGAAGCTC CATGGCTGCC TTCCTGATTC AGACCAAGGA CAATCCCATG 
AAGGCCGTGG GTGTACTGGC TGGTGTCATG GCCATTGTTG TGGCCATAAC CGTCCTCATC 
TCCACAGCCA CCTTCTGGCG TAACAAGAAG TCTAACAAGG TCCTGCCTGT GCGGCGTGTG 
CTCCGTAGAA GGCCCAGCCC TGCACCCCAC ACAGTACGAA TAGAATGGCT CAAATTCCGG 
AGGGCCAAGG CTGCTTCCAA GTTTATACTC AAAGAGGATC CTCCCAATGA GAACTGCAAT 
AACAGCAGAG TGGGAGTCAC GGTGCCCCCA AGAGCTCCAG CTCTCCCACC GCCCCCCAAA 
ATGGCATCCA GTACAGTGGC CCAACAGACA GTGCCTACTG TCTCTGGATC CCTTACCCCA 
CAGCCATCCC AACAGTTACC CACACCCAAA CCCCTGGGAG GCCCTGCTCA GTCTTCTTTG 
GTGTCAGAGC TCAAGCAAAA GTTTGAGAAG AAGAGTTTAG GTAACAAGGC TTATGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446024.1
CDS	201..2780
Translation	MRRGPQVALVLGLLCIYLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVIVVTDANDEAPRFLQEPYNILVPENTPAGSSIFKVQAEDKDTGSGGSVTYFLQSLHSSKFTVDRHSGVLRLQAGATLDYEKSRAHFITVVAKDGGGRLRGADVVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGLFEINETSGAISVLQSPAQLRREVYELHVQVTEVNSSGSPAAQSTVPVIIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKSLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENVPGGSNVVAVTAVDPDTGPWGKVQYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGEYSWSLQVQAKDRGSPSFSTTALLKIDITDTERLSRSSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKSNKVLPVRRVLRRRPSPAPHTVRIEWLKFRRAKAASKFILKEDPPNENCNNSRVGVTVPPRAPALPPPPKMASSTVAQQTVPTVSGSLTPQPSQQLPTPKPLGGPAQSSLVSELKQKFEKKSLGNKAYV

Target ORF information:

RefSeq Version	NM_053572.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cadherin-related family member 1 (Cdhr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053572.1

ORF Insert Sequence:

ATGAGGCGTG GCCCACAGGT TGCCCTGGTC CTGGGGCTGC TGTGCATTTA CCTAGCCCAG 
GCCAACTTTG CCCCTCACTT CTTTGACAAT GGAGTGGGCA GCACCAACGG AAACATGGCC 
CTGTTCAGCC TCCCAGAAGA CACTCCTGTA GGTTCTCATG TGTACACACT AAATGGGACT 
GACCCCGAGG GAGACCCTAT CTCCTACCAT ATCAGCTTTG ACCCCAGCAC TAGAAGTGTC 
TTTTCTGTTG ACCCCAATTT TGGAAACATC ACCCTGGTGG AAGAGCTGGA CAGAGAGAGA 
GAGGATGAGA TAGAAGCCAT CATCAGCATC TCCGACGGCC TGAACCTGGT GGCAGAGAAA 
GTTGTGATAG TGGTGACAGA TGCCAATGAT GAAGCACCCA GGTTCCTCCA GGAGCCTTAC 
AACATCCTGG TTCCAGAGAA CACACCTGCT GGGAGCAGCA TCTTTAAGGT ACAGGCAGAG 
GACAAGGACA CAGGCTCTGG AGGCAGTGTC ACCTACTTCC TTCAGAGCCT ACACTCCTCC 
AAGTTCACCG TAGACCGTCA CAGCGGGGTG CTGCGACTCC AGGCTGGGGC CACACTGGAC 
TATGAGAAGT CGAGGGCTCA TTTCATCACT GTGGTTGCCA AGGATGGTGG GGGCAGGCTT 
CGAGGAGCTG ATGTGGTATT CTCAGCCACC ACGACTGTCA CCATCAATGT GGAAGATGTT 
CAGGACACAG CCCCTATATT CGTGGGTACA CCCTACTATG GTTATGTGTA CGAAGACACC 
CTTCCGGGCT CAGAGGTGCT GACGGTGGTT GCCATAGATG GAGACCGAGG CAAACCCAAC 
CACATCCTCT ATAGGCTCTT GAATGAGAGT GATGGACTCT TTGAAATTAA TGAGACATCT 
GGAGCCATCT CCGTCCTTCA GAGCCCTGCC CAGCTCCGAA GAGAGGTGTA TGAGCTTCAT 
GTACAGGTGA CAGAGGTCAA CTCTTCAGGA AGCCCAGCTG CTCAGTCCAC AGTCCCAGTG 
ATCATCAGGA TCGTGGACCT CAACAACCAC CCTCCAACCT TCTATGGAGA GAGCGGGCCC 
CAGAACAAGT TTGAACTATC TATGTTTGAG CACCCGCCCC AGGGGGAAAT CCTCCGTGGA 
CTCAAGATCA CTGTCAATGA CTCTGACCAG GGAGCCAATG CCAAATTCAA CTTACGGCTG 
GTGGGACCTG GAGGCATCTT TCGAGTGGTG CCACAGACAG TCCTGAATGA AGCCCAAGTG 
ACCATCATAG TGGAAAACTC AGCTGCCATT GACTTTGAAA AGTCTAAGTC GTTAACCTTC 
AAGCTCCTGG CCATTGAAGT GAACACCCCG GAGAAGTTCA GCTCCACAGC AGACATTGTG 
ATCCAGCTTC TGGACACCAA TGATAATGTT CCCAAGTTCA CCTCTCACTA CTACATCGCC 
AGGATCCCAG AGAATGTTCC AGGGGGCTCC AATGTGGTGG CTGTCACAGC TGTGGATCCA 
GATACAGGAC CATGGGGCAA AGTCCAGTAT TCCATTTATG GGACCGGATC AGACCTCTTC 
TTGATTCACC CATCCACTGG GCTTATCTAC ACTCAGCCCT GGGCCAGCCT GGATGCTGAG 
GGCACTTCGA GGTACAACTT TTATGTGAAG GCAGAAGACA TGGATGGGAG GTACAGCCTG 
GCTGAGGTGT TTGTCACTCT GTTGGATGTC AATGACCACT ACCCCCAGTT TGTACAGAGT 
GTCCAGGAGA AGACGATGGT GCTGGGGACC CCACTGAAAA TTGAGGCCAC AGACCAGGAT 
GCAGAGGAAC CAAACAACTT GGTCGACTAC TCCATTACCC GTGCAGAGCC AGTCAACGTG 
TTTGACATAG ATGCACACAC AGGGGAGATC AGGCTCAAGA ATTCCATCCG CTCCTTGGAG 
GCCCTACACA ACATTACACC CAGCGGGGAA TACTCATGGT CCCTACAGGT GCAGGCCAAG 
GACCGAGGAT CTCCATCTTT CAGCACAACA GCCTTACTCA AGATCGACAT CACAGACACA 
GAGAGGCTGT CCAGAAGCTC CATGGCTGCC TTCCTGATTC AGACCAAGGA CAATCCCATG 
AAGGCCGTGG GTGTACTGGC TGGTGTCATG GCCATTGTTG TGGCCATAAC CGTCCTCATC 
TCCACAGCCA CCTTCTGGCG TAACAAGAAG TCTAACAAGG TCCTGCCTGT GCGGCGTGTG 
CTCCGTAGAA GGCCCAGCCC TGCACCCCAC ACAGTACGAA TAGAATGGCT CAAATTCCGG 
AGGGCCAAGG CTGCTTCCAA GTTTATACTC AAAGAGGATC CTCCCAATGA GAACTGCAAT 
AACAGCAGAG TGGGAGTCAC GGTGCCCCCA AGAGCTCCAG CTCTCCCACC GCCCCCCAAA 
ATGGCATCCA GTACAGTGGC CCAACAGACA GTGCCTACTG TCTCTGGATC CCTTACCCCA 
CAGCCATCCC AACAGTTACC CACACCCAAA CCCCTGGGAG GCCCTGCTCA GTCTTCTTTG 
GTGTCAGAGC TCAAGCAAAA GTTTGAGAAG AAGAGTTTAG GTAACAAGGC TTATGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of a novel mutation in the CDHR1 gene in a family with recessive retinal degeneration.
Archives of ophthalmology (Chicago, Ill. : 1960)130(10)1301-8(2012 Oct)
Duncan JL,Roorda A,Navani M,Vishweswaraiah S,Syed R,Soudry S,Ratnam K,Gudiseva HV,Lee P,Gaasterland T,Ayyagari R

Mutations in PCDH21 cause autosomal recessive cone-rod dystrophy.
Journal of medical genetics47(10)665-9(2010 Oct)
Ostergaard E,Batbayli M,Duno M,Vilhelmsen K,Rosenberg T

Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.
The Journal of clinical investigation118(8)2908-16(2008 Aug)
Yang Z,Chen Y,Lillo C,Chien J,Yu Z,Michaelides M,Klein M,Howes KA,Li Y,Kaminoh Y,Chen H,Zhao C,Chen Y,Al-Sheikh YT,Karan G,Corbeil D,Escher P,Kamaya S,Li C,Johnson S,Frederick JM,Zhao Y,Wang C,Cameron DJ,Huttner WB,Schorderet DF,Munier FL,Moore AT,Birch DG,Baehr W,Hunt DM,Williams DS,Zhang K

A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival.
Neuron32(5)775-86(2001 Dec)
Rattner A,Smallwood PM,Williams J,Cooke C,Savchenko A,Lyubarsky A,Pugh EN,Nathans J

Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.
Brain research. Molecular brain research94(1-2)85-95(2001 Oct)
Nakajima D,Nakayama M,Kikuno R,Hirosawa M,Nagase T,Ohara O