Mia cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mia
Entrez Gene ID	81510
Full Name	melanoma inhibitory activity
Synonyms	Cdrap,Mia1
General protein information	Preferred Names melanoma inhibitory activity Names melanoma-derived growth regulatory protein CD-RAP cartilage-derived retinoic acid-sensitive protein melanoma inhibitory activity 1 melanoma inhibitory activity protein melanoma inhibitory activity/condrocyte-derived retinoic acid sensitive protein homolog (MIA/CD-RAP) melanoma-derived growth regulatory protein-like
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	may be involved in cartilage development [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_030852.2	NP_110479.1	melanoma-derived growth regulatory protein precursor

Pathways from BioSystems

Homologies

	MIA	XP_001098600.1
Rattus norvegicus (Norway rat)	Mia	NP_110479.1
Homo sapiens (human)	MIA	NP_001189482.1
Canis lupus familiaris (dog)	MIA	XP_541610.3
Bos taurus (cattle)	MIA	NP_776361.1
Mus musculus (house mouse)	Mia	NP_062267.2
Xenopus tropicalis (tropical clawed frog)	mia	NP_001135716.1
Pan troglodytes (chimpanzee)	MIA	XP_001146858.1
Danio rerio (zebrafish)	zgc:194158	NP_001122226.1

Gene Ontology
Bibliography

Related articles in PubMed

New insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of gene expression in a rat model.
Kerachian MA, Cournoyer D, Harvey EJ, Chow TY, B?gin LR, Nahal A, S?guin C
Arthritis research & therapy12(3)R124(2010)

Transcriptional Co-activators CREB-binding protein/p300 increase chondrocyte Cd-rap gene expression by multiple mechanisms including sequestration of the repressor CCAAT/enhancer-binding protein.
Imamura T, Imamura C, Iwamoto Y, Sandell LJ
The Journal of biological chemistry280(17)16625-34(2005 Apr)

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.
Bo?da B, El-Amraoui A, Bahloul A, Goodyear R, Daviet L, Blanchard S, Perfettini I, Fath KR, Shorte S, Reiners J, Houdusse A, Legrain P, Wolfrum U, Richardson G, Petit C
The EMBO journal21(24)6689-99(2002 Dec)

Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.
Moser M, Bosserhoff AK, Hunziker EB, Sandell L, F?ssler R, Buettner R
Molecular and cellular biology22(5)1438-45(2002 Mar)

Gene expression changes associated with chemically induced rat mammary carcinogenesis.
Lu J, Pei H, Kaeck M, Thompson HJ
Molecular carcinogenesis20(2)204-15(1997 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CREB-binding protein/p300 increase chondrocyte Cd-rap gene expression by multiple mechanisms including sequestration of the repressor CCAAT/enhancer-binding protein
Title: Transcriptional Co-activators CREB-binding protein/p300 increase chondrocyte Cd-rap gene expression by multiple mechanisms including sequestration of the repressor CCAAT/enhancer-binding protein.

The following Mia gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mia cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12220	NM_030852.2 Latest version!	Rattus norvegicus MIA SH3 domain containing (Mia), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mia ( NM_030852.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_110479.1 Rattus norvegicus MIA SH3 domain containing (Mia), mRNA.

Price & Availability↑

CloneID	ORa12220
Clone ID Related Accession (Same CDS sequence)	NM_030852.2
Accession Version	NM_030852.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	melanoma-derived growth regulatory protein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from U67884.1 and CA509768.1. On Aug 4, 2012 this sequence version replaced NM_030852.1. ##Evidence-Data-START## Transcript exon combination :: U67884.1, CB796570.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END##

ATGGTGTGCT CCCCAGTGCT CCTTGGTATT GTCATCTTGT CTGTTTTTTC AGGCCTCAGC 
AGGGCTGATC GAGCCATGCC CAAGCTGGCT GACCGGAAGC TGTGTGCAGA TGAGGAGTGT 
AGCCATCCTA TCTCCATGGC TGTGGCCCTT CAGGACTACG TGGCCCCTGA TTGCCGCTTC 
TTGACTATAT ACAGGGGCCA AGTGGTATAT GTCTTCTCCA AGTTGAAAGG CCGTGGACGG 
CTTTTCTGGG GAGGCAGTGT GCAGGGAGAT TACTATGGAG ACCTGGCAGC CCACCTGGGC 
TATTTCCCCA GTAGCATTGT CCGGGAGGAC CTGACTCTGA AACCTGGCAA AGTCGATATG 
AAGACAGATG AATGGGATTT CTACTGTCAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_110479.1
CDS	13..405
Translation	MVCSPVLLGIVILSVFSGLSRADRAMPKLADRKLCADEECSHPISMAVALQDYVAPDCRFLTIYRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAAHLGYFPSSIVREDLTLKPGKVDMKTDEWDFYCQ

Target ORF information:

RefSeq Version	NM_030852.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MIA SH3 domain containing (Mia), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030852.2

ORF Insert Sequence:

ATGGTGTGCT CCCCAGTGCT CCTTGGTATT GTCATCTTGT CTGTTTTTTC AGGCCTCAGC 
AGGGCTGATC GAGCCATGCC CAAGCTGGCT GACCGGAAGC TGTGTGCAGA TGAGGAGTGT 
AGCCATCCTA TCTCCATGGC TGTGGCCCTT CAGGACTACG TGGCCCCTGA TTGCCGCTTC 
TTGACTATAT ACAGGGGCCA AGTGGTATAT GTCTTCTCCA AGTTGAAAGG CCGTGGACGG 
CTTTTCTGGG GAGGCAGTGT GCAGGGAGAT TACTATGGAG ACCTGGCAGC CCACCTGGGC 
TATTTCCCCA GTAGCATTGT CCGGGAGGAC CTGACTCTGA AACCTGGCAA AGTCGATATG 
AAGACAGATG AATGGGATTT CTACTGTCAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

New insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of gene expression in a rat model.
Arthritis research & therapy12(3)R124(2010)
Kerachian MA,Cournoyer D,Harvey EJ,Chow TY,B?gin LR,Nahal A,S?guin C

Transcriptional Co-activators CREB-binding protein/p300 increase chondrocyte Cd-rap gene expression by multiple mechanisms including sequestration of the repressor CCAAT/enhancer-binding protein.
The Journal of biological chemistry280(17)16625-34(2005 Apr)
Imamura T,Imamura C,Iwamoto Y,Sandell LJ

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.
The EMBO journal21(24)6689-99(2002 Dec)
Bo?da B,El-Amraoui A,Bahloul A,Goodyear R,Daviet L,Blanchard S,Perfettini I,Fath KR,Shorte S,Reiners J,Houdusse A,Legrain P,Wolfrum U,Richardson G,Petit C

Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.
Molecular and cellular biology22(5)1438-45(2002 Mar)
Moser M,Bosserhoff AK,Hunziker EB,Sandell L,F?ssler R,Buettner R

Gene expression changes associated with chemically induced rat mammary carcinogenesis.
Molecular carcinogenesis20(2)204-15(1997 Oct)
Lu J,Pei H,Kaeck M,Thompson HJ