Hint1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hint1
Entrez Gene ID	690660
Full Name	histidine triad nucleotide binding protein 1
Synonyms	Pkci,Prkci
General protein information	Preferred Names histidine triad nucleotide binding protein 1 Names histidine triad nucleotide-binding protein 1 17 kDa inhibitor of protein kinase C PKCI-1 adenosine 5'-monophosphoramidase protein kinase C inhibitor 1 protein kinase C, iota protein kinase C-interacting protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q22
Summary	plays a role in intracellular protein transport; facilitates Rab2 GTPase mediated vesicle budding from pre-Golgi intermediates [RGD, Sep 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001109607.1	NP_001103077.1	histidine triad nucleotide-binding protein 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	HINT1	XP_003310848.1
Drosophila melanogaster (fruit fly)	CG2862	NP_608711.3
Xenopus tropicalis (tropical clawed frog)	hint1	NP_001016165.1
Bos taurus (cattle)	HINT1	NP_787006.1
Danio rerio (zebrafish)	hint1	NP_001005593.1
	HINT1	XP_001099859.1
Mus musculus (house mouse)	Hint1	NP_032274.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006353	XP_316373.4
Caenorhabditis elegans (roundworm)	hint-1	NP_492056.1
Arabidopsis thaliana (thale cress)	HIT3	NP_567038.1
Oryza sativa (rice)	Os03g0322500	NP_001049967.1
Canis lupus familiaris (dog)	HINT1	XP_531895.2
Gallus gallus (chicken)	HINT1	NP_990020.1
Homo sapiens (human)	HINT1	NP_005331.1
Rattus norvegicus (Norway rat)	Hint1	NP_001103077.1

Gene Ontology
Bibliography

Related articles in PubMed

Histidine triad nucleotide-binding protein 1 (HINT1) regulates Ca(2+) signaling in mouse fibroblasts and neuronal cells via store-operated Ca(2+) entry pathway.
Linde CI, Feng B, Wang JB, Golovina VA
American journal of physiology. Cell physiology304(11)C1098-104(2013 Jun)

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family.
Klein MG, Yao Y, Slosberg ED, Lima CD, Doki Y, Weinstein IB
Experimental cell research244(1)26-32(1998 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hint1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hint1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10511	NM_001109607.1 Latest version!	Rattus norvegicus histidine triad nucleotide binding protein 1 (Hint1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hint1 ( NM_001109607.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001103077.1 Rattus norvegicus histidine triad nucleotide binding protein 1 (Hint1), mRNA.

Price & Availability↑

CloneID	ORa10511
Clone ID Related Accession (Same CDS sequence)	NM_001109607.1
Accession Version	NM_001109607.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	histidine triad nucleotide-binding protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On Oct 4, 2007 this sequence version replaced XM_001073678.1. ##Evidence-Data-START## Transcript exon combination :: CD568080.1, BC168732.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGACG AGATTGCCAA GGCTCAAGTG GCCCAGCCCG GTGGCGACAC GATCTTCGGC 
AAGATCATCC GCAAAGAAAT CCCGGCCAAG ATCATTTTCG AGGACGATCG GTGTCTTGCT 
TTTCATGACA TTTCCCCTCA AGCACCAACA CACTTTCTGG TGATACCCAA GAAGCACATA 
TCCCAGATTT CTGTGGCAGA TGATGATGAT GAAAGTCTTC TAGGACATTT AATGATTGTT 
GGCAAGAAAT GTGCTGCGGA TCTGGGCCTG AAGCGCGGGT ATCGGATGGT GGTGAATGAA 
GGTGCAGACG GGGGGCAGTC TGTCTATCAT ATTCACCTCC ACGTCCTTGG AGGTCGGCAG 
ATGAACTGGC CTCCTGGTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001103077.1
CDS	59..439
Translation	MADEIAKAQVAQPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQMNWPPG

Target ORF information:

RefSeq Version	NM_001109607.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus histidine triad nucleotide binding protein 1 (Hint1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109607.1

ORF Insert Sequence:

ATGGCTGACG AGATTGCCAA GGCTCAAGTG GCCCAGCCCG GTGGCGACAC GATCTTCGGC 
AAGATCATCC GCAAAGAAAT CCCGGCCAAG ATCATTTTCG AGGACGATCG GTGTCTTGCT 
TTTCATGACA TTTCCCCTCA AGCACCAACA CACTTTCTGG TGATACCCAA GAAGCACATA 
TCCCAGATTT CTGTGGCAGA TGATGATGAT GAAAGTCTTC TAGGACATTT AATGATTGTT 
GGCAAGAAAT GTGCTGCGGA TCTGGGCCTG AAGCGCGGGT ATCGGATGGT GGTGAATGAA 
GGTGCAGACG GGGGGCAGTC TGTCTATCAT ATTCACCTCC ACGTCCTTGG AGGTCGGCAG 
ATGAACTGGC CTCCTGGTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Histidine triad nucleotide-binding protein 1 (HINT1) regulates Ca(2+) signaling in mouse fibroblasts and neuronal cells via store-operated Ca(2+) entry pathway.
American journal of physiology. Cell physiology304(11)C1098-104(2013 Jun)
Linde CI,Feng B,Wang JB,Golovina VA

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Buschow SI,van Balkom BW,Aalberts M,Heck AJ,Wauben M,Stoorvogel W

Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family.
Experimental cell research244(1)26-32(1998 Oct)
Klein MG,Yao Y,Slosberg ED,Lima CD,Doki Y,Weinstein IB