Pllp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pllp
Entrez Gene ID	64364
Full Name	plasmolipin
Synonyms	Tm4sf11
General protein information	Preferred Names plasmolipin Names plasmolipin plasma membrane proteolipid (plasmolipin) transmembrane 4 superfamily member 11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19p13
Summary	induces the formation of voltage dependent K+ selective ion channels in lipid bilayers; may play a role in myelination [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022533.1	NP_071978.1	plasmolipin

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PLLP	NP_001025732.1
Xenopus tropicalis (tropical clawed frog)	LOC100493581	XP_002931714.1
Canis lupus familiaris (dog)	PLLP	XP_003433877.2
Rattus norvegicus (Norway rat)	Pllp	NP_071978.1
Homo sapiens (human)	PLLP	NP_057077.1
Danio rerio (zebrafish)	si:dkey-73n10.4	NP_001116171.1
Bos taurus (cattle)	PLLP	NP_001092593.1
Pan troglodytes (chimpanzee)	PLLP	XP_001145227.1
Mus musculus (house mouse)	Pllp	NP_080661.1

Gene Ontology
Bibliography

Related articles in PubMed

Proteolipid plasmolipin: localization in polarized cells, regulated expression and lipid raft association in CNS and PNS myelin.
Bosse F, Hasse B, Pippirs U, Greiner-Petter R, M?ller HW
Journal of neurochemistry86(2)508-18(2003 Jul)

Full-lenth cloning, expression and cellular localization of rat plasmolipin mRNA, a proteolipid of PNS and CNS.
Gillen C, Gleichmann M, Greiner-Petter R, Zoidl G, Kupfer S, Bosse F, Auer J, M?ller HW
The European journal of neuroscience8(2)405-14(1996 Feb)

Molecular cloning of plasmolipin. Characterization of a novel proteolipid restricted to brain and kidney.
Fischer I, Sapirstein VS
The Journal of biological chemistry269(40)24912-9(1994 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The proteolipid plasmolipin is a structural component of apical membranes of polarized cells; asymmetric distribution of plasmolipin in compact myelin, as well as in epithelial cells of kidney and stomach was noted
Title: Proteolipid plasmolipin: localization in polarized cells, regulated expression and lipid raft association in CNS and PNS myelin.

The following Pllp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pllp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05867	NM_022533.1 Latest version!	Rattus norvegicus plasmolipin (Pllp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pllp ( NM_022533.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071978.1 Rattus norvegicus plasmolipin (Pllp), mRNA.

Price & Availability↑

CloneID	ORa05867
Clone ID Related Accession (Same CDS sequence)	NM_022533.1
Accession Version	NM_022533.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	plasmolipin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z49858.1. On Nov 17, 2006 this sequence version replaced XM_001061847.1. ##Evidence-Data-START## Transcript exon combination :: Z49858.1, BC078823.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAGT TCCCGTCGAA AGTGAGCACC AGGACCAGCA GCCCCGCGCA GGGCGTGGGA 
GCATCTGTGT CTGCGATGCG ACCGGACCTG GGCTTTGTGC GCTCCGCCCT TGGGGTGCTC 
GCGCTTCTGC AGCTGGTGCT GGGGCTGCTG GTGTGGGCCT TGATTGCTGA CACCCCATAC 
CACCTGTATC CTGCCTACGG CTGGGTTATG TTTGTAGCTG TCTTCCTCTG GCTGGTAACA 
ATTGTCTTCT TCATCATCTA CCTGTTTCAA CTGCACATGA AGTTGTATAT GGTGCCCTGG 
CCGTTGGTGT TACTGGTCTT CTTTGTTGCT GCCACCGTCC TCTATATCAC CGCCTTTGTC 
GCCTGTGCGG CGGCGGTCGA TCTGACATCC CTGAGGGGCT CCCGACCGTA CAACCAGCGC 
TCGGCTGCCT CTTTCTTTGC TTGTCTGGTG ATGATTGCCT ACGGACTGAG TGCTTTCTTC 
AGCTTCCAGG CCTGGCGAGG AGTGGGCAGC AACGCGGCCA CGAGTCAGAT GGCTGGGGGC 
TACTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071978.1
CDS	216..764
Translation	MAEFPSKVSTRTSSPAQGVGASVSAMRPDLGFVRSALGVLALLQLVLGLLVWALIADTPYHLYPAYGWVMFVAVFLWLVTIVFFIIYLFQLHMKLYMVPWPLVLLVFFVAATVLYITAFVACAAAVDLTSLRGSRPYNQRSAASFFACLVMIAYGLSAFFSFQAWRGVGSNAATSQMAGGYS

Target ORF information:

RefSeq Version	NM_022533.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus plasmolipin (Pllp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022533.1

ORF Insert Sequence:

ATGGCGGAGT TCCCGTCGAA AGTGAGCACC AGGACCAGCA GCCCCGCGCA GGGCGTGGGA 
GCATCTGTGT CTGCGATGCG ACCGGACCTG GGCTTTGTGC GCTCCGCCCT TGGGGTGCTC 
GCGCTTCTGC AGCTGGTGCT GGGGCTGCTG GTGTGGGCCT TGATTGCTGA CACCCCATAC 
CACCTGTATC CTGCCTACGG CTGGGTTATG TTTGTAGCTG TCTTCCTCTG GCTGGTAACA 
ATTGTCTTCT TCATCATCTA CCTGTTTCAA CTGCACATGA AGTTGTATAT GGTGCCCTGG 
CCGTTGGTGT TACTGGTCTT CTTTGTTGCT GCCACCGTCC TCTATATCAC CGCCTTTGTC 
GCCTGTGCGG CGGCGGTCGA TCTGACATCC CTGAGGGGCT CCCGACCGTA CAACCAGCGC 
TCGGCTGCCT CTTTCTTTGC TTGTCTGGTG ATGATTGCCT ACGGACTGAG TGCTTTCTTC 
AGCTTCCAGG CCTGGCGAGG AGTGGGCAGC AACGCGGCCA CGAGTCAGAT GGCTGGGGGC 
TACTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteolipid plasmolipin: localization in polarized cells, regulated expression and lipid raft association in CNS and PNS myelin.
Journal of neurochemistry86(2)508-18(2003 Jul)
Bosse F,Hasse B,Pippirs U,Greiner-Petter R,M?ller HW

Full-lenth cloning, expression and cellular localization of rat plasmolipin mRNA, a proteolipid of PNS and CNS.
The European journal of neuroscience8(2)405-14(1996 Feb)
Gillen C,Gleichmann M,Greiner-Petter R,Zoidl G,Kupfer S,Bosse F,Auer J,M?ller HW

Molecular cloning of plasmolipin. Characterization of a novel proteolipid restricted to brain and kidney.
The Journal of biological chemistry269(40)24912-9(1994 Oct)
Fischer I,Sapirstein VS