Lsr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lsr
Entrez Gene ID	64355
Full Name	lipolysis stimulated lipoprotein receptor
Synonyms	Lisch7
General protein information	Preferred Names lipolysis stimulated lipoprotein receptor Names lipolysis-stimulated lipoprotein receptor lipolysis-stimulated receptor lipolysis-stimulated remnant receptor liver-specific bHLH-Zip transcription factor 7
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	binds apoB, apoE, and triglyceride-rich lipoprotein (chylomicrons and very low density lipoprotein (VLDL)); may mediate the partitioning of dietary lipid between different tissues [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006228845.3	XP_006228907.1	lipolysis-stimulated lipoprotein receptor isoform X2
XM_006228844.3	XP_006228906.1	lipolysis-stimulated lipoprotein receptor isoform X1
NM_032616.1	NP_116005.1	lipolysis-stimulated lipoprotein receptor precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	lsr	NP_001015935.1
Homo sapiens (human)	LSR	NP_991403.1
Pan troglodytes (chimpanzee)	LSR	NP_001243519.1
Canis lupus familiaris (dog)	LSR	XP_005616775.1
Bos taurus (cattle)	LSR	NP_001076863.1
Mus musculus (house mouse)	Lsr	NP_059101.1
Rattus norvegicus (Norway rat)	Lsr	NP_116005.1
Danio rerio (zebrafish)	lsr	NP_001020643.1

Gene Ontology
Bibliography

Related articles in PubMed

LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation.
Sohet F, Lin C, Munji RN, Lee SY, Ruderisch N, Soung A, Arnold TD, Derugin N, Vexler ZS, Yen FT, Daneman R
The Journal of cell biology208(6)703-11(2015 Mar)

JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet.
Nakatsu D, Kano F, Taguchi Y, Sugawara T, Nishizono T, Nishikawa K, Oda Y, Furuse M, Murata M
Genes to cells : devoted to molecular & cellular mechanisms19(7)565-81(2014 Jul)

Lipolysis-stimulated lipoprotein receptor: a novel membrane protein of tricellular tight junctions.
Furuse M, Oda Y, Higashi T, Iwamoto N, Masuda S
Annals of the New York Academy of Sciences125754-8(2012 Jun)

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lsr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lsr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09045	NM_032616.1 Latest version!	Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00
ORa22620	XM_006228844.3 Latest version!	Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa22621	XM_006228845.3 Latest version!	Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lsr ( NM_032616.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_116005.1 Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), mRNA.

Price & Availability↑

CloneID	ORa09045
Clone ID Related Accession (Same CDS sequence)	NM_032616.1
Accession Version	NM_032616.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1782bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	lipolysis-stimulated lipoprotein receptor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF119667.1. ##Evidence-Data-START## Transcript exon combination :: AF119667.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCCGG CGGCCGGCGC GTGTGCTGGG GCGCCTGACT CCCACCCAGC TACCGTGGTC 
TTCGTGTGTC TCTTTCTCAT CATTTTCTGC CCAGACCCTG CCAGTGCCAT CCAGGTGACT 
GTGTCTGACC CCTACCACGT AGTGATCCTG TTCCAGCCAG TGACCCTGCC CTGCACCTAT 
CAGATGAGCA ACACTCTCAC AGTCCCCATC GTGATCTGGA AGTACAAGTC ATTCTGCCGG 
GACCGTATTG CCGATGCCTT CTCTCCTGCC AGTGTGGACA ACCAGCTAAA TGCCCAGTTG 
GCAGCTGGCA ACCCCGGCTA CAACCCCTAT GTGGAGTGCC AGGACAGTGT ACGCACTGTC 
AGGGTGGTGG CCACCAAACA GGGCAATGCG GTGACCCTGG GAGACTACTA CCAAGGCAGG 
AGGATCACCA TAACAGGAAA TGCTGACCTG ACCTTCGAGC AGACAGCCTG GGGAGACAGT 
GGAGTGTATT ACTGCTCTGT GGTCTCGGCC CAAGATCTGG ATGGAAACAA CGAGGCGTAC 
GCAGAGCTCA TCGTCCTTGG CAGGACCTCA GAGGCCCCTG AGCTCCTACC TGGTTTTCGG 
GCGGGGCCCT TGGAAGATTG GCTCTTTGTG GTCGTGGTCT GCCTGGCGAG CCTCCTCCTC 
TTCCTCCTCC TGGGCATCTG CTGGTGCCAG TGCTGTCCTC ACACCTGCTG CTGCTATGTC 
CGATGTCCCT GCTGCCCAGA CAAGTGCTGT TGCCCTGAGG CTCTTTATGC TGCTGGCAAA 
GCAGCCACCT CAGGTGTCCC GAGCATCTAT GCCCCCAGCA TCTATACCCA CCTCTCACCT 
GCCAAGACCC CACCACCTCC GCCTGCCATG ATTCCCATGG GCCCTCCCTA TGGGTACCCT 
GGAGACTTTG ACAGACATAG CTCAGTTGGT GGCCACAGCT CCCAAGTACC CCTGCTGCGT 
GACGTGGATG GCAGTGTATC TTCAGAAGTA CGAAGTGGCT ACAGGATCCA GGCTAACCAG 
CAAGATGACT CCATGAGGGT CCTATACTAT ATGGAGAAAG AGCTAGCCAA CTTTGACCCT 
TCCCGACCTG GCCCTCCCAA TGGCAGAGTG GAACGGGCCA TGAGTGAAGT AACCTCCCTC 
CATGAAGATG ACTGGCGATC GAGGCCTTCC AGGGCTCCTG CCCTCACCCC CATCAGGGAT 
GAGGAGTGGA ATCGCCACTC CCCACAGAGT CCCAGAACAT GGGAGCAGGA ACCCCTTCAA 
GAACAACCAA GGGGTGGTTG GGGGTCTGGA CGCCCTCGGG CCCGCTCTGT GGATGCTCTA 
GATGATATCA ACCGGCCTGG CTCCACTGAA TCAGGACGGT CTTCTCCCCC AAGTAGTGGA 
CGGAGAGGAC GGGCCTATGC ACCTCCAAGA AGTCGCAGCC GGGATGACCT CTATGACCCG 
GACGATCCTA GGGACTTGCC ACATTCCCGA GATCCCCACT ATTATGACGA CATCAGGTCT 
AGAGATCCAC GTGCTGACCC CAGATCCCGT CAGCGATCCC GAGATCCTCG GGATGCTGGC 
TTCAGGTCAA GGGACCCTCA GTATGATGGG CGACTATTAG AAGAGGCTTT AAAGAAAAAG 
GGGTCGGGCG AGAGAAGGAG GGTTTACAGG GAGGAAGAAG AGGAAGAGGA GGGCCAATAC 
CCCCCAGCAC CTCCACCTTA CTCAGAGACT GACTCGCAGG CCTCACGGGA GAGGAGGCTG 
AAAAAGAATT TGGCCCTGAG TCGGGAAAGT TTAGTCGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116005.1
CDS	218..1999
Translation	MAPAAGACAGAPDSHPATVVFVCLFLIIFCPDPASAIQVTVSDPYHVVILFQPVTLPCTYQMSNTLTVPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFEQTAWGDSGVYYCSVVSAQDLDGNNEAYAELIVLGRTSEAPELLPGFRAGPLEDWLFVVVVCLASLLLFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSIYTHLSPAKTPPPPPAMIPMGPPYGYPGDFDRHSSVGGHSSQVPLLRDVDGSVSSEVRSGYRIQANQQDDSMRVLYYMEKELANFDPSRPGPPNGRVERAMSEVTSLHEDDWRSRPSRAPALTPIRDEEWNRHSPQSPRTWEQEPLQEQPRGGWGSGRPRARSVDALDDINRPGSTESGRSSPPSSGRRGRAYAPPRSRSRDDLYDPDDPRDLPHSRDPHYYDDIRSRDPRADPRSRQRSRDPRDAGFRSRDPQYDGRLLEEALKKKGSGERRRVYREEEEEEEGQYPPAPPPYSETDSQASRERRLKKNLALSRESLVV

Target ORF information:

RefSeq Version	NM_032616.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032616.1

ORF Insert Sequence:

ATGGCGCCGG CGGCCGGCGC GTGTGCTGGG GCGCCTGACT CCCACCCAGC TACCGTGGTC 
TTCGTGTGTC TCTTTCTCAT CATTTTCTGC CCAGACCCTG CCAGTGCCAT CCAGGTGACT 
GTGTCTGACC CCTACCACGT AGTGATCCTG TTCCAGCCAG TGACCCTGCC CTGCACCTAT 
CAGATGAGCA ACACTCTCAC AGTCCCCATC GTGATCTGGA AGTACAAGTC ATTCTGCCGG 
GACCGTATTG CCGATGCCTT CTCTCCTGCC AGTGTGGACA ACCAGCTAAA TGCCCAGTTG 
GCAGCTGGCA ACCCCGGCTA CAACCCCTAT GTGGAGTGCC AGGACAGTGT ACGCACTGTC 
AGGGTGGTGG CCACCAAACA GGGCAATGCG GTGACCCTGG GAGACTACTA CCAAGGCAGG 
AGGATCACCA TAACAGGAAA TGCTGACCTG ACCTTCGAGC AGACAGCCTG GGGAGACAGT 
GGAGTGTATT ACTGCTCTGT GGTCTCGGCC CAAGATCTGG ATGGAAACAA CGAGGCGTAC 
GCAGAGCTCA TCGTCCTTGG CAGGACCTCA GAGGCCCCTG AGCTCCTACC TGGTTTTCGG 
GCGGGGCCCT TGGAAGATTG GCTCTTTGTG GTCGTGGTCT GCCTGGCGAG CCTCCTCCTC 
TTCCTCCTCC TGGGCATCTG CTGGTGCCAG TGCTGTCCTC ACACCTGCTG CTGCTATGTC 
CGATGTCCCT GCTGCCCAGA CAAGTGCTGT TGCCCTGAGG CTCTTTATGC TGCTGGCAAA 
GCAGCCACCT CAGGTGTCCC GAGCATCTAT GCCCCCAGCA TCTATACCCA CCTCTCACCT 
GCCAAGACCC CACCACCTCC GCCTGCCATG ATTCCCATGG GCCCTCCCTA TGGGTACCCT 
GGAGACTTTG ACAGACATAG CTCAGTTGGT GGCCACAGCT CCCAAGTACC CCTGCTGCGT 
GACGTGGATG GCAGTGTATC TTCAGAAGTA CGAAGTGGCT ACAGGATCCA GGCTAACCAG 
CAAGATGACT CCATGAGGGT CCTATACTAT ATGGAGAAAG AGCTAGCCAA CTTTGACCCT 
TCCCGACCTG GCCCTCCCAA TGGCAGAGTG GAACGGGCCA TGAGTGAAGT AACCTCCCTC 
CATGAAGATG ACTGGCGATC GAGGCCTTCC AGGGCTCCTG CCCTCACCCC CATCAGGGAT 
GAGGAGTGGA ATCGCCACTC CCCACAGAGT CCCAGAACAT GGGAGCAGGA ACCCCTTCAA 
GAACAACCAA GGGGTGGTTG GGGGTCTGGA CGCCCTCGGG CCCGCTCTGT GGATGCTCTA 
GATGATATCA ACCGGCCTGG CTCCACTGAA TCAGGACGGT CTTCTCCCCC AAGTAGTGGA 
CGGAGAGGAC GGGCCTATGC ACCTCCAAGA AGTCGCAGCC GGGATGACCT CTATGACCCG 
GACGATCCTA GGGACTTGCC ACATTCCCGA GATCCCCACT ATTATGACGA CATCAGGTCT 
AGAGATCCAC GTGCTGACCC CAGATCCCGT CAGCGATCCC GAGATCCTCG GGATGCTGGC 
TTCAGGTCAA GGGACCCTCA GTATGATGGG CGACTATTAG AAGAGGCTTT AAAGAAAAAG 
GGGTCGGGCG AGAGAAGGAG GGTTTACAGG GAGGAAGAAG AGGAAGAGGA GGGCCAATAC 
CCCCCAGCAC CTCCACCTTA CTCAGAGACT GACTCGCAGG CCTCACGGGA GAGGAGGCTG 
AAAAAGAATT TGGCCCTGAG TCGGGAAAGT TTAGTCGTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsr ( XM_006228844.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228906.1 Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22620
Clone ID Related Accession (Same CDS sequence)	XM_006228844.3
Accession Version	XM_006228844.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lipolysis-stimulated lipoprotein receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228844.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCCGG CGGCCGGCGC GTGTGCTGGG GCGCCTGACT CCCACCCAGC TACCGTGGTC 
TTCGTGTGTC TCTTTCTCAT CATTTTCTGC CCAGACCCTG CCAGTGCCAT CCAGGTGACT 
GTGTCTGACC CCTACCACGT AGTGATCCTG TTCCAGCCAG TGACCCTGCC CTGCACCTAT 
CAGATGAGCA ACACTCTCAC AGTCCCCATC GTGATCTGGA AGTACAAGTC ATTCTGCCGG 
GACCGTATTG CCGATGCCTT CTCTCCTGCC AGTGTGGACA ACCAGCTAAA TGCCCAGTTG 
GCAGCTGGCA ACCCCGGCTA CAACCCCTAT GTGGAGTGCC AGGACAGTGT ACGCACTGTC 
AGGGTGGTGG CCACCAAACA GGGCAATGCG GTGACCCTGG GAGACTACTA CCAAGGCAGG 
AGGATCACCA TAACAGGAAA TGCTGACCTG ACCTTCGAGC AGACAGCCTG GGGAGACAGT 
GGAGTGTATT ACTGCTCTGT GGTCTCGGCC CAAGATCTGG ATGGAAACAA CGAGGCGTAC 
GCAGAGCTCA TCGTCCTTGA TTGGCTCTTT GTGGTCGTGG TCTGCCTGGC GAGCCTCCTC 
CTCTTCCTCC TCCTGGGCAT CTGCTGGTGC CAGTGCTGTC CTCACACCTG CTGCTGCTAT 
GTCCGATGTC CCTGCTGCCC AGACAAGTGC TGTTGCCCTG AGGCTCTTTA TGCTGCTGGC 
AAAGCAGCCA CCTCAGGTGT CCCGAGCATC TATGCCCCCA GCATCTATAC CCACCTCTCA 
CCTGCCAAGA CCCCACCACC TCCGCCTGCC ATGATTCCCA TGGGCCCTCC CTATGGGTAC 
CCTGGAGACT TTGACAGACA TAGCTCAGTT GGTGGCCACA GCTCCCAAGT ACCCCTGCTG 
CGTGACGTGG ATGGCAGTGT ATCTTCAGAA GTACGAAGTG GCTACAGGAT CCAGGCTAAC 
CAGCAAGATG ACTCCATGAG GGTCCTATAC TATATGGAGA AAGAGCTAGC CAACTTTGAC 
CCTTCCCGAC CTGGCCCTCC CAATGGCAGA GTGGAACGGG CCATGAGTGA AGTAACCTCC 
CTCCATGAAG ATGACTGGCG ATCGAGGCCT TCCAGGGCTC CTGCCCTCAC CCCCATCAGG 
GATGAGGAGT GGAATCGCCA CTCCCCACAG AGTCCCAGAA CATGGGAGCA GGAACCCCTT 
CAAGAACAAC CAAGGGGTGG TTGGGGGTCT GGACGGCCTC GGGCCCGCTC TGTGGATGCT 
CTAGATGATA TCAACCGGCC TGGCTCCACT GAATCAGGAC GGTCTTCTCC CCCAAGTAGT 
GGACGGAGAG GACGAGCCTA TGCACCTCCA AGAAGTCGCA GCCGGGATGA CCTCTATGAC 
CCGGACGATC CTAGGGACTT GCCACATTCC CGAGATCCCC ACTATTATGA CGACATCAGG 
TCTAGAGATC CACGTGCTGA CCCCAGATCC CGTCAGCGAT CCCGAGATCC TCGGGATGCT 
GGCTTCAGGT CAAGGGACCC TCAGTATGAT GGGCGACTAT TAGAAGAGGC TTTAAAGAAA 
AAGGGGTCGG GCGAGAGAAG GAGGGTTTAC AGGGAGGAAG AAGAGGAAGA GGAGGGCCAA 
TACCCCCCAG CACCTCCACC TTACTCAGAG ACTGACTCGC AGGCCTCACG GGAGAGGAGG 
CTGAAAAAGA ATTTGGCCCT GAGTCGGGAA AGTTTAGTCG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228906.1
CDS	217..1941
Translation	MAPAAGACAGAPDSHPATVVFVCLFLIIFCPDPASAIQVTVSDPYHVVILFQPVTLPCTYQMSNTLTVPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFEQTAWGDSGVYYCSVVSAQDLDGNNEAYAELIVLDWLFVVVVCLASLLLFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSIYTHLSPAKTPPPPPAMIPMGPPYGYPGDFDRHSSVGGHSSQVPLLRDVDGSVSSEVRSGYRIQANQQDDSMRVLYYMEKELANFDPSRPGPPNGRVERAMSEVTSLHEDDWRSRPSRAPALTPIRDEEWNRHSPQSPRTWEQEPLQEQPRGGWGSGRPRARSVDALDDINRPGSTESGRSSPPSSGRRGRAYAPPRSRSRDDLYDPDDPRDLPHSRDPHYYDDIRSRDPRADPRSRQRSRDPRDAGFRSRDPQYDGRLLEEALKKKGSGERRRVYREEEEEEEGQYPPAPPPYSETDSQASRERRLKKNLALSRESLVV

Target ORF information:

RefSeq Version	XM_006228844.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228844.3

ORF Insert Sequence:

ATGGCGCCGG CGGCCGGCGC GTGTGCTGGG GCGCCTGACT CCCACCCAGC TACCGTGGTC 
TTCGTGTGTC TCTTTCTCAT CATTTTCTGC CCAGACCCTG CCAGTGCCAT CCAGGTGACT 
GTGTCTGACC CCTACCACGT AGTGATCCTG TTCCAGCCAG TGACCCTGCC CTGCACCTAT 
CAGATGAGCA ACACTCTCAC AGTCCCCATC GTGATCTGGA AGTACAAGTC ATTCTGCCGG 
GACCGTATTG CCGATGCCTT CTCTCCTGCC AGTGTGGACA ACCAGCTAAA TGCCCAGTTG 
GCAGCTGGCA ACCCCGGCTA CAACCCCTAT GTGGAGTGCC AGGACAGTGT ACGCACTGTC 
AGGGTGGTGG CCACCAAACA GGGCAATGCG GTGACCCTGG GAGACTACTA CCAAGGCAGG 
AGGATCACCA TAACAGGAAA TGCTGACCTG ACCTTCGAGC AGACAGCCTG GGGAGACAGT 
GGAGTGTATT ACTGCTCTGT GGTCTCGGCC CAAGATCTGG ATGGAAACAA CGAGGCGTAC 
GCAGAGCTCA TCGTCCTTGA TTGGCTCTTT GTGGTCGTGG TCTGCCTGGC GAGCCTCCTC 
CTCTTCCTCC TCCTGGGCAT CTGCTGGTGC CAGTGCTGTC CTCACACCTG CTGCTGCTAT 
GTCCGATGTC CCTGCTGCCC AGACAAGTGC TGTTGCCCTG AGGCTCTTTA TGCTGCTGGC 
AAAGCAGCCA CCTCAGGTGT CCCGAGCATC TATGCCCCCA GCATCTATAC CCACCTCTCA 
CCTGCCAAGA CCCCACCACC TCCGCCTGCC ATGATTCCCA TGGGCCCTCC CTATGGGTAC 
CCTGGAGACT TTGACAGACA TAGCTCAGTT GGTGGCCACA GCTCCCAAGT ACCCCTGCTG 
CGTGACGTGG ATGGCAGTGT ATCTTCAGAA GTACGAAGTG GCTACAGGAT CCAGGCTAAC 
CAGCAAGATG ACTCCATGAG GGTCCTATAC TATATGGAGA AAGAGCTAGC CAACTTTGAC 
CCTTCCCGAC CTGGCCCTCC CAATGGCAGA GTGGAACGGG CCATGAGTGA AGTAACCTCC 
CTCCATGAAG ATGACTGGCG ATCGAGGCCT TCCAGGGCTC CTGCCCTCAC CCCCATCAGG 
GATGAGGAGT GGAATCGCCA CTCCCCACAG AGTCCCAGAA CATGGGAGCA GGAACCCCTT 
CAAGAACAAC CAAGGGGTGG TTGGGGGTCT GGACGGCCTC GGGCCCGCTC TGTGGATGCT 
CTAGATGATA TCAACCGGCC TGGCTCCACT GAATCAGGAC GGTCTTCTCC CCCAAGTAGT 
GGACGGAGAG GACGAGCCTA TGCACCTCCA AGAAGTCGCA GCCGGGATGA CCTCTATGAC 
CCGGACGATC CTAGGGACTT GCCACATTCC CGAGATCCCC ACTATTATGA CGACATCAGG 
TCTAGAGATC CACGTGCTGA CCCCAGATCC CGTCAGCGAT CCCGAGATCC TCGGGATGCT 
GGCTTCAGGT CAAGGGACCC TCAGTATGAT GGGCGACTAT TAGAAGAGGC TTTAAAGAAA 
AAGGGGTCGG GCGAGAGAAG GAGGGTTTAC AGGGAGGAAG AAGAGGAAGA GGAGGGCCAA 
TACCCCCCAG CACCTCCACC TTACTCAGAG ACTGACTCGC AGGCCTCACG GGAGAGGAGG 
CTGAAAAAGA ATTTGGCCCT GAGTCGGGAA AGTTTAGTCG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsr ( XM_006228845.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228907.1 Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa22621
Clone ID Related Accession (Same CDS sequence)	XM_006228845.3
Accession Version	XM_006228845.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lipolysis-stimulated lipoprotein receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228845.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCCGG CGGCCGGCGC GTGTGCTGGG GCGCCTGACT CCCACCCAGC TACCGTGGTC 
TTCGTGTGTC TCTTTCTCAT CATTTTCTGC CCAGACCCTG CCAGTGCCAT CCAGGTGACT 
GTGTCTGACC CCTACCACGT AGTGATCCTG TTCCAGCCAG TGACCCTGCC CTGCACCTAT 
CAGATGAGCA ACACTCTCAC AGTCCCCATC GTGATCTGGA AGTACAAGTC ATTCTGCCGG 
GACCGTATTG CCGATGCCTT CTCTCCTGCC AGTGTGGACA ACCAGCTAAA TGCCCAGTTG 
GCAGCTGGCA ACCCCGGCTA CAACCCCTAT GTGGAGTGCC AGGACAGTGT ACGCACTGTC 
AGGGTGGTGG CCACCAAACA GGGCAATGCG GTGACCCTGG GAGACTACTA CCAAGGCAGG 
AGGATCACCA TAACAGGAAA TGCTGACCTG ACCTTCGAGC AGACAGCCTG GGGAGACAGT 
GGAGTGTATT ACTGCTCTGT GGTCTCGGCC CAAGATCTGG ATGGAAACAA CGAGGCGTAC 
GCAGAGCTCA TCGTCCTTGT TTATGCTGCT GGCAAAGCAG CCACCTCAGG TGTCCCGAGC 
ATCTATGCCC CCAGCATCTA TACCCACCTC TCACCTGCCA AGACCCCACC ACCTCCGCCT 
GCCATGATTC CCATGGGCCC TCCCTATGGG TACCCTGGAG ACTTTGACAG ACATAGCTCA 
GTTGGTGGCC ACAGCTCCCA AGTACCCCTG CTGCGTGACG TGGATGGCAG TGTATCTTCA 
GAAGTACGAA GTGGCTACAG GATCCAGGCT AACCAGCAAG ATGACTCCAT GAGGGTCCTA 
TACTATATGG AGAAAGAGCT AGCCAACTTT GACCCTTCCC GACCTGGCCC TCCCAATGGC 
AGAGTGGAAC GGGCCATGAG TGAAGTAACC TCCCTCCATG AAGATGACTG GCGATCGAGG 
CCTTCCAGGG CTCCTGCCCT CACCCCCATC AGGGATGAGG AGTGGAATCG CCACTCCCCA 
CAGAGTCCCA GAACATGGGA GCAGGAACCC CTTCAAGAAC AACCAAGGGG TGGTTGGGGG 
TCTGGACGGC CTCGGGCCCG CTCTGTGGAT GCTCTAGATG ATATCAACCG GCCTGGCTCC 
ACTGAATCAG GACGGTCTTC TCCCCCAAGT AGTGGACGGA GAGGACGAGC CTATGCACCT 
CCAAGAAGTC GCAGCCGGGA TGACCTCTAT GACCCGGACG ATCCTAGGGA CTTGCCACAT 
TCCCGAGATC CCCACTATTA TGACGACATC AGGTCTAGAG ATCCACGTGC TGACCCCAGA 
TCCCGTCAGC GATCCCGAGA TCCTCGGGAT GCTGGCTTCA GGTCAAGGGA CCCTCAGTAT 
GATGGGCGAC TATTAGAAGA GGCTTTAAAG AAAAAGGGGT CGGGCGAGAG AAGGAGGGTT 
TACAGGGAGG AAGAAGAGGA AGAGGAGGGC CAATACCCCC CAGCACCTCC ACCTTACTCA 
GAGACTGACT CGCAGGCCTC ACGGGAGAGG AGGCTGAAAA AGAATTTGGC CCTGAGTCGG 
GAAAGTTTAG TCGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228907.1
CDS	217..1794
Translation	MAPAAGACAGAPDSHPATVVFVCLFLIIFCPDPASAIQVTVSDPYHVVILFQPVTLPCTYQMSNTLTVPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFEQTAWGDSGVYYCSVVSAQDLDGNNEAYAELIVLVYAAGKAATSGVPSIYAPSIYTHLSPAKTPPPPPAMIPMGPPYGYPGDFDRHSSVGGHSSQVPLLRDVDGSVSSEVRSGYRIQANQQDDSMRVLYYMEKELANFDPSRPGPPNGRVERAMSEVTSLHEDDWRSRPSRAPALTPIRDEEWNRHSPQSPRTWEQEPLQEQPRGGWGSGRPRARSVDALDDINRPGSTESGRSSPPSSGRRGRAYAPPRSRSRDDLYDPDDPRDLPHSRDPHYYDDIRSRDPRADPRSRQRSRDPRDAGFRSRDPQYDGRLLEEALKKKGSGERRRVYREEEEEEEGQYPPAPPPYSETDSQASRERRLKKNLALSRESLVV

Target ORF information:

RefSeq Version	XM_006228845.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lipolysis stimulated lipoprotein receptor (Lsr), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228845.3

ORF Insert Sequence:

ATGGCGCCGG CGGCCGGCGC GTGTGCTGGG GCGCCTGACT CCCACCCAGC TACCGTGGTC 
TTCGTGTGTC TCTTTCTCAT CATTTTCTGC CCAGACCCTG CCAGTGCCAT CCAGGTGACT 
GTGTCTGACC CCTACCACGT AGTGATCCTG TTCCAGCCAG TGACCCTGCC CTGCACCTAT 
CAGATGAGCA ACACTCTCAC AGTCCCCATC GTGATCTGGA AGTACAAGTC ATTCTGCCGG 
GACCGTATTG CCGATGCCTT CTCTCCTGCC AGTGTGGACA ACCAGCTAAA TGCCCAGTTG 
GCAGCTGGCA ACCCCGGCTA CAACCCCTAT GTGGAGTGCC AGGACAGTGT ACGCACTGTC 
AGGGTGGTGG CCACCAAACA GGGCAATGCG GTGACCCTGG GAGACTACTA CCAAGGCAGG 
AGGATCACCA TAACAGGAAA TGCTGACCTG ACCTTCGAGC AGACAGCCTG GGGAGACAGT 
GGAGTGTATT ACTGCTCTGT GGTCTCGGCC CAAGATCTGG ATGGAAACAA CGAGGCGTAC 
GCAGAGCTCA TCGTCCTTGT TTATGCTGCT GGCAAAGCAG CCACCTCAGG TGTCCCGAGC 
ATCTATGCCC CCAGCATCTA TACCCACCTC TCACCTGCCA AGACCCCACC ACCTCCGCCT 
GCCATGATTC CCATGGGCCC TCCCTATGGG TACCCTGGAG ACTTTGACAG ACATAGCTCA 
GTTGGTGGCC ACAGCTCCCA AGTACCCCTG CTGCGTGACG TGGATGGCAG TGTATCTTCA 
GAAGTACGAA GTGGCTACAG GATCCAGGCT AACCAGCAAG ATGACTCCAT GAGGGTCCTA 
TACTATATGG AGAAAGAGCT AGCCAACTTT GACCCTTCCC GACCTGGCCC TCCCAATGGC 
AGAGTGGAAC GGGCCATGAG TGAAGTAACC TCCCTCCATG AAGATGACTG GCGATCGAGG 
CCTTCCAGGG CTCCTGCCCT CACCCCCATC AGGGATGAGG AGTGGAATCG CCACTCCCCA 
CAGAGTCCCA GAACATGGGA GCAGGAACCC CTTCAAGAAC AACCAAGGGG TGGTTGGGGG 
TCTGGACGGC CTCGGGCCCG CTCTGTGGAT GCTCTAGATG ATATCAACCG GCCTGGCTCC 
ACTGAATCAG GACGGTCTTC TCCCCCAAGT AGTGGACGGA GAGGACGAGC CTATGCACCT 
CCAAGAAGTC GCAGCCGGGA TGACCTCTAT GACCCGGACG ATCCTAGGGA CTTGCCACAT 
TCCCGAGATC CCCACTATTA TGACGACATC AGGTCTAGAG ATCCACGTGC TGACCCCAGA 
TCCCGTCAGC GATCCCGAGA TCCTCGGGAT GCTGGCTTCA GGTCAAGGGA CCCTCAGTAT 
GATGGGCGAC TATTAGAAGA GGCTTTAAAG AAAAAGGGGT CGGGCGAGAG AAGGAGGGTT 
TACAGGGAGG AAGAAGAGGA AGAGGAGGGC CAATACCCCC CAGCACCTCC ACCTTACTCA 
GAGACTGACT CGCAGGCCTC ACGGGAGAGG AGGCTGAAAA AGAATTTGGC CCTGAGTCGG 
GAAAGTTTAG TCGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation.
The Journal of cell biology208(6)703-11(2015 Mar)
Sohet F,Lin C,Munji RN,Lee SY,Ruderisch N,Soung A,Arnold TD,Derugin N,Vexler ZS,Yen FT,Daneman R

JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet.
Genes to cells : devoted to molecular & cellular mechanisms19(7)565-81(2014 Jul)
Nakatsu D,Kano F,Taguchi Y,Sugawara T,Nishizono T,Nishikawa K,Oda Y,Furuse M,Murata M

Lipolysis-stimulated lipoprotein receptor: a novel membrane protein of tricellular tight junctions.
Annals of the New York Academy of Sciences125754-8(2012 Jun)
Furuse M,Oda Y,Higashi T,Iwamoto N,Masuda S

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Buschow SI,van Balkom BW,Aalberts M,Heck AJ,Wauben M,Stoorvogel W

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR