Scn7a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scn7a
Entrez Gene ID	64155
Full Name	sodium voltage-gated channel alpha subunit 7
Synonyms	Na-G,Scn6a
General protein information	Preferred Names sodium voltage-gated channel alpha subunit 7 Names sodium channel protein type 7 subunit alpha sodium channel voltage-gated type VI alpha polypeptide sodium channel, voltage-gated, type 6, alpha polypeptide sodium channel, voltage-gated, type VII, alpha subunit
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q21
Summary	glial Na-channel alpha subunit [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031686.1	NP_113874.1	sodium channel protein type 7 subunit alpha
XM_006234296.3	XP_006234358.1	sodium channel protein type 7 subunit alpha isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SCN7A	NP_002967.2
Pan troglodytes (chimpanzee)	SCN7A	XP_515875.4
Canis lupus familiaris (dog)	SCN7A	XP_545504.3
Bos taurus (cattle)	SCN7A	XP_002685417.2
Mus musculus (house mouse)	Scn7a	NP_033161.2
	SCN7A	XP_002808047.1
Rattus norvegicus (Norway rat)	Scn7a	NP_113874.1

Gene Ontology
Bibliography

Related articles in PubMed

Enhanced SCN7A/Nax expression contributes to bone cancer pain by increasing excitability of neurons in dorsal root ganglion.
Ke CB, He WS, Li CJ, Shi D, Gao F, Tian YK
Neuroscience22780-9(2012 Dec)

Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)

Voltage-gated sodium channel expression in rat spiral ganglion neurons.
Fryatt AG, Vial C, Mulheran M, Gunthorpe MJ, Grubb BD
Molecular and cellular neurosciences42(4)399-407(2009 Dec)

Sodium-level-sensitive sodium channel Na(x) is expressed in glial laminate processes in the sensory circumventricular organs.
Watanabe E, Hiyama TY, Shimizu H, Kodama R, Hayashi N, Miyata S, Yanagawa Y, Obata K, Noda M
American journal of physiology. Regulatory, integrative and comparative physiology290(3)R568-76(2006 Mar)

Specific Na+ sensors are functionally expressed in a neuronal population of the median preoptic nucleus of the rat.
Grob M, Drolet G, Mouginot D
The Journal of neuroscience : the official journal of the Society for Neuroscience24(16)3974-84(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results of this study demonstrated that enhanced expression of SCN7A/Nax channel within distinct subpopulation of DRG neurons contributes to bone cancer pain by increasing the excitability of these neurons
Title: Enhanced SCN7A/Nax expression contributes to bone cancer pain by increasing excitability of neurons in dorsal root ganglion.

Data demonstrate predominant localisation of Na(V)1.6 and Na(V)1.7 on SGN cell bodies and Na(V)1.1 on axonal processes in rat brain.
Title: Voltage-gated sodium channel expression in rat spiral ganglion neurons.

This study shows that a neuronal population of the median preoptic nucleus acts as functional Na+ sensors and that the Na(X) channel might represent the molecular basis for the extracellular sodium level sensing in these neurons.
Title: Specific Na+ sensors are functionally expressed in a neuronal population of the median preoptic nucleus of the rat.

The following Scn7a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scn7a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13743	NM_031686.1 Latest version!	Rattus norvegicus sodium voltage-gated channel alpha subunit 7 (Scn7a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00
ORa25921	XM_006234296.3 Latest version!	Rattus norvegicus sodium voltage-gated channel alpha subunit 7 (Scn7a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scn7a ( NM_031686.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113874.1 Rattus norvegicus sodium voltage-gated channel alpha subunit 7 (Scn7a), mRNA.

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CloneID	ORa13743
Clone ID Related Accession (Same CDS sequence)	NM_031686.1
Accession Version	NM_031686.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5109bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	sodium channel protein type 7 subunit alpha
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y09164.1. ##Evidence-Data-START## Transcript exon combination :: Y09164.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTTGACTT CCCCAGAGCC GAAGGGCCTT GTCCCATTCA CGGCAGAGTC ACTTGAACTT 
ATAAAAAATC ACATTGCTAA AAAATGCAAC GAAGAGCATG AAGAAGAAGA TTTAAAACCA 
AGCCGGGATA TAGAAGCAGG CAAAAAACTT CCATTTGCCT ATGGAACCCT TCCTCAAGGA 
ACCGTGTCAG AGCCCTTGGA AGATGTGGAT CCATACTACT ATGTTAAGAG AAATACTTTC 
ATGGTCTTAA ACAGAAACAG AGTCATCTTC AGGTTCAATG CGGTTTCCAT CCTCTGCACG 
TTGTCTCCTT TAAGCTCTCT CAGAAGAGCT GTTATCAAGG TTTTGGTGCA CCCCCTTTTG 
CGCCTGCTGA TTTTAATTAG TGTTCTCACC GACAGCATAC TTATGTGCAT GAGTAACCTA 
CCGGAATGGA TATTGGCAGT AGAGAATACT TGCTTGGGAA TTTACACATT CGAAATACTG 
GTAAAAGTCA TTGCAAGAGG TATCTGGGCA GGGTCATTTT CCTTCCTTGG GGATCTTTGG 
AACTGGCTTG ATTTCAGTGT AACTTTGTTC GAGCTTATCA CAAGGTCTTC ACCTCTAAGC 
TCCCTTCCAA TGTTTAAAAC AATAAGAACC TTGCGAATTT TGAAGATCAT CCCTTTGAAC 
CATGGCCTGC AGTCTATTGT GGTGACGCTG GTCCAGTGTT TGAAGAAACT ACTCGGAGCC 
ATTGCCCTAG CTCTGTTTTT TCTGACTGTG TCTTCGCTAT TCGGGATGGG TCTCTTCATG 
GGCAACCTGA AGCACAAATG TGTGCGATGG CCCCAAGAAG ATGGAAATGA TGTGATGTAC 
AGTGGAACTG GAAGCCAGTA CCATATTCTA GAAAGAGAAA ACTTCTACTA TATGGAAGGC 
GCGAGATACG CTCTCCTCTG CGGCAACAAG ACAGATGCCG GCCTGTGTCC AGAAGGTTAT 
ATGTGTGTAA AAGAGGGCTC AAATCCTGAC AATGGCTTCA CAAGTTTTGA CAATTTTGGC 
TGGGCTCTAC TGGCTATGTT TCGATTGATG ACTCAGGATT ACCCTGAATT ACTTTATCAC 
CAGATCCTTT ATGCTTCAGG AAAGATCTAC ATGATATTTT TTGTTCTGAT CAGTTTCTGG 
TTTGCCTTCT ATATGGCAAG TTTGTTCTTG GGCATCCTCA CTATGGCCTA TGAACAGGAG 
AAGCAGAGAG CTTCTGAGGA GTCTAGAGAC ATGGATTCTA AATGTCATCA GACTGTGAAA 
GAATTCGAGG AAGAACATGA AGGAGCTGAG CTTCAGTGTA TCTGGTTTTA TGAGGAGGTT 
CTTGATCTAC TTGGACTTGA GCTTTGTATC AAGGAGATGG AAACTACACA AATAGAAATG 
AAGAAAAGAT CACCAACTTC TATAAACACC ACATTGGATA TACTGGAAGA CACTGCCCTT 
GGACACAAAG AAGAACCAGA AACATCCAGG AAGGAATGCC CACTCTGTTG GTATAAGTTT 
ACTAAAACCT GCTTTATCTG GAAATGCTCT CCCTGTTGGA TAAAACTGAA TGAGTTTGCT 
GACAGAATTA TAACACACCC ATTGTTTGAT CTTTTCCTTG TTATATGCAT CATTTTAAAC 
ATATGCTTCC TGGCCCTAGA ACACTTTCCA ATGAGTGAGG AGCTCATGTC ACTCCTTGCC 
ATTGGAAACT TGGTTTTTAT TGGAATTTAC ACAATAGAAA TGATTTTGAA GATAATCGCT 
ATGCATCCAT ATGGGTATTT CCAAATAAGC TGGCATATTT TTGACAGTAT TCTTGTGGTT 
TTGGGATTAA CAGAAATGTT ACTAGCAGAT ATTGAAGAAA TAACTGTTTT TATATTAGTC 
CCATTGATAT TTATAAAATT GGGAAAATAT GCACCACCAT TTAAGAATTT GATGCGTATT 
CTTGGTAGAG CATTGGTGGC CCTGAAAGAC TTGGTCCTGT TGGTCTCCAT TTTCATTTAC 
TTCTCTGCCG TGTTTGGCAT GAAGCTGTTT GGTCGAAGTT ACAAAGATTG TGTCTGCCAC 
GTAGATCAAG ACTGTCAACG CCAACGTTGG CACATGAGTG ACTTCCTCCA CGCCTACGTG 
ACTGTGTTCC GAATCCTCTG CGGAGAGTGG ATAGAGACAT TATGGGAGTG TATGGAGGTT 
GCAGGCGAGG CCTGGTGTAT TCCATTTTAC ATGATGGTCA TTTTAATTGG AAATTTATTG 
ATACTTTACC TCTTTGTGGG ATTGGTGAGC TCATTTGCTT CATACGATGC TACCACAGAA 
GTGAGCAAAG AAGCCAAAAA CCTTCAGCTT GCAGTGGCAT GGATAAAAAT GGTAATAAAC 
TGTGTGCTTC TTAAAATACT GTGCAAAGAA AAAACTGTTT CTACAGAAGC AACAGACCAA 
ACATGTGATC CAAGTGTTAA AGAGAATATT TCTGGTCATA CTCTTTCTGA ACTGAGCAAC 
ACCCAAACAT TCCTCAGATA CAAGGACCAG AGCAGTGGTA CTGAGAAAAC TCCAGTGACT 
GAGTCTGAGA GCCAATCCCT GATTGCTAGT CCCAGTGTAT CAGAAACTGT GCCAATTGCT 
TCAGGAGAAT CCGATATAGA AAACCTGGAT AACAAGGAGA CTCGGAGCAA GTCTGCAAAT 
GGAAGCAGTA AAGAGAAAAT GAAGCAATCT AGTTCATCTG AGTGCAGCAC GGTTGATATT 
GCTATTTCTG AAGAAGAAGA AATGGTCTAT GAACATGAAA AGTCGAAGCT TCATAAAAAT 
GGTTATGAAC GCAAATCTTC AGCTGGCCAA GTCAGTAGAG AATCTAGGAA TGGAAAGATT 
TGGAGGAACA TAAGGAAAAC TTGCTGCAAG ATAGTGGAGA ACAGCTGGTT TGAGTGTTTC 
ATTGGCCTGG TCACTCTGCT CTGCACAGGC ACTCTGGCTC TGGAAGACAT ATATATTCAT 
CAGCGGAAAA CCATTAAAAT CTTCCTGGAG TATGGAGACA TGATATTTGC TTACATCTTC 
ATTCTGGAGA TGCTTCTCAA GTGGGTGGCC TACGGCTTTA AAGCCTACTT CTCTAACAAC 
TGGTACAAGC TGGACTTCAT GGTCGTTATC GTGTTGTGTC TTAGCTTAAA AGGCAAAACT 
CGAGAGGACC TGAACCCTCT GCCTTCCATA AAGTTCCTTC GAGCACTTAG AGTTCTGTCT 
CAGTTTGAAA GAATGAAGGT GGTTCTGAGA GCTTTGATAA AAACAACCTT ACCCGCTGTG 
AGCGTGTTTC TGGTCTGCCT AATGATCTGG CTGCTTTTCA GTGTTATGGG AGTGTTCTTA 
TTCGCTGGCA AGTTCTATGA ATGCATTGAC CCAACAAGGG GAGAAAGATT CTCTGTATTT 
GAAGTTATGA ATAAGAGTCA GTGTGAAAAC CTGGTATTTA ATGAATCAAT GCCATGGGAG 
AATGCAAAAC TGAACTTTGA TAATGTTGGA AATGGTTTTC TTTCTTTGTT CCAAGTGGCA 
ACATTTAATG GGTGGATCAG TATTATGAAT TCAGCAATTG ACTCTGTTGG TGTGTACATG 
CAGCCTAGTT TTGAGCACAG CCTCCACATG TACACTTACT TTATCATCTT TGTTGTGTTT 
GGATTATTTC TTCCCTTGTG TATGCTGATT GGTGTTATTA TCAGGAATTT CAACAAGCAG 
AAAATTAAGC AGGGAGGATC AAATATCTTT ATAACGGTAA AGCAGAAGAA GCAGTACCGG 
GCACTGAAGA AGCTCTTGTA TGCAGACTCT CAGAAACCAG CAGCCCGCCC TAGAAACAAG 
TTCCAAGGCT TCATTTGTGA CGTAGTAACA CATCGTGTCT TTAATGTCGT CGTCGTACTT 
CTTATCTGTT TCCAAGCAAC AACCATTATG ATACAAAATG ATGAGCAGAG TCCACAAATT 
GAAACCGCTG TCTTCTGGAT GAACTCCCTT TTTACCATGC TGTTCACTCT GGAATGCATA 
CTGAAGCTCA CCGCCTTCCG CTGCCACTAT TTCACCAGCG CATGGAATGT TCATGACTTT 
ATGGTGGTCG TTTTCTCCAT TACAGGACTG CTGCTGCCTT TGTCAATAGG ACAATACTTT 
GTGCCTCCTT CACTGGTGCA GCTGCTTCTT CTCTCTCGCA TCATCCATGT CCTGCGTCCT 
GGGAAAGGAC CAAAGGTGTT CCATGATCTG ATGCTTCCCT TGATGCTGTC ACTCCCAGCA 
CTGCTCAACA TTGGTCTTCT CATCTTCCTG GTCATGTTCA TCTACGCCAT CTTTGGAATG 
TACAACTTCG CCTACGTGAA GAAAGAAGCC GGAATTAATG ATGTGTCCAA CTTTGAGACC 
TTTGGAAGCA GTATGCTTTG TCTCTTTCAA GTTACAACAT TTTCTGGTTG GGACGGGATG 
CTGGATGCAA TTTTCAACAG TCAGTGGTCT GACTGCGATC CTGATAAAAT TAACCCAGGG 
ACTCAGGTCA GGGGAGACTG TGGGAGCCCT TCTGTTGGGA TTTTTTATTT TGTCAGTTAC 
ATCCTCATAT CATGGTTGAT CATTGTTAAT ATGTACGTTG TTTTGATCAT GGAGTTCTTA 
AGTATTCCTT CTAAGAGAAA AAACAGGACC TTGAGCGAAG ATGACTTTAG GAGATTCTTC 
AAGGTATGGA ACAGGTTTGA CCCTGACAGG ACCCAGTACA TAGACTCTAC TAAGCTTTCT 
GATTTTGCAG CTGCTCTCGA TCCTCCTCTT TTCATGGCAA AACCAAACAA GGGCCAGCTT 
GTAGCCATGG ATCTCCCCAT GGCTGCAGGA GACAGAATCC ATTGCCTTGA TATTTTGCTT 
GCCTTTACGA AAAGAGTGAT GGGAAAGGAT GAGCGGGTGG AGAAGATCCT TTCAGAGATA 
GAATCTGGGT TTATGTTAGC GAACCCTTTC AAAATTACGT ATGAGCCGAT TACAACGACT 
TTGAAACGCA AACAAGAGGC AGTCTCAGCC ACTATCATCC AGCGGGCATA CAAAAGTTAC 
CGCTTAAGGC AAAGTGACAA AAAGATACAA GATATCCCGG AAATAGATGA TGGCAGGGAG 
GATCCTAACT CTAAAGGTGT CCACTCTGGT CAAATCGAGG AAAAGGCATC TATTCAGACC 
CAGATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113874.1
CDS	11..5119
Translation	MLTSPEPKGLVPFTAESLELIKNHIAKKCNEEHEEEDLKPSRDIEAGKKLPFAYGTLPQGTVSEPLEDVDPYYYVKRNTFMVLNRNRVIFRFNAVSILCTLSPLSSLRRAVIKVLVHPLLRLLILISVLTDSILMCMSNLPEWILAVENTCLGIYTFEILVKVIARGIWAGSFSFLGDLWNWLDFSVTLFELITRSSPLSSLPMFKTIRTLRILKIIPLNHGLQSIVVTLVQCLKKLLGAIALALFFLTVSSLFGMGLFMGNLKHKCVRWPQEDGNDVMYSGTGSQYHILERENFYYMEGARYALLCGNKTDAGLCPEGYMCVKEGSNPDNGFTSFDNFGWALLAMFRLMTQDYPELLYHQILYASGKIYMIFFVLISFWFAFYMASLFLGILTMAYEQEKQRASEESRDMDSKCHQTVKEFEEEHEGAELQCIWFYEEVLDLLGLELCIKEMETTQIEMKKRSPTSINTTLDILEDTALGHKEEPETSRKECPLCWYKFTKTCFIWKCSPCWIKLNEFADRIITHPLFDLFLVICIILNICFLALEHFPMSEELMSLLAIGNLVFIGIYTIEMILKIIAMHPYGYFQISWHIFDSILVVLGLTEMLLADIEEITVFILVPLIFIKLGKYAPPFKNLMRILGRALVALKDLVLLVSIFIYFSAVFGMKLFGRSYKDCVCHVDQDCQRQRWHMSDFLHAYVTVFRILCGEWIETLWECMEVAGEAWCIPFYMMVILIGNLLILYLFVGLVSSFASYDATTEVSKEAKNLQLAVAWIKMVINCVLLKILCKEKTVSTEATDQTCDPSVKENISGHTLSELSNTQTFLRYKDQSSGTEKTPVTESESQSLIASPSVSETVPIASGESDIENLDNKETRSKSANGSSKEKMKQSSSSECSTVDIAISEEEEMVYEHEKSKLHKNGYERKSSAGQVSRESRNGKIWRNIRKTCCKIVENSWFECFIGLVTLLCTGTLALEDIYIHQRKTIKIFLEYGDMIFAYIFILEMLLKWVAYGFKAYFSNNWYKLDFMVVIVLCLSLKGKTREDLNPLPSIKFLRALRVLSQFERMKVVLRALIKTTLPAVSVFLVCLMIWLLFSVMGVFLFAGKFYECIDPTRGERFSVFEVMNKSQCENLVFNESMPWENAKLNFDNVGNGFLSLFQVATFNGWISIMNSAIDSVGVYMQPSFEHSLHMYTYFIIFVVFGLFLPLCMLIGVIIRNFNKQKIKQGGSNIFITVKQKKQYRALKKLLYADSQKPAARPRNKFQGFICDVVTHRVFNVVVVLLICFQATTIMIQNDEQSPQIETAVFWMNSLFTMLFTLECILKLTAFRCHYFTSAWNVHDFMVVVFSITGLLLPLSIGQYFVPPSLVQLLLLSRIIHVLRPGKGPKVFHDLMLPLMLSLPALLNIGLLIFLVMFIYAIFGMYNFAYVKKEAGINDVSNFETFGSSMLCLFQVTTFSGWDGMLDAIFNSQWSDCDPDKINPGTQVRGDCGSPSVGIFYFVSYILISWLIIVNMYVVLIMEFLSIPSKRKNRTLSEDDFRRFFKVWNRFDPDRTQYIDSTKLSDFAAALDPPLFMAKPNKGQLVAMDLPMAAGDRIHCLDILLAFTKRVMGKDERVEKILSEIESGFMLANPFKITYEPITTTLKRKQEAVSATIIQRAYKSYRLRQSDKKIQDIPEIDDGREDPNSKGVHSGQIEEKASIQTQI

Target ORF information:

RefSeq Version	NM_031686.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sodium voltage-gated channel alpha subunit 7 (Scn7a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031686.1

ORF Insert Sequence:

ATGTTGACTT CCCCAGAGCC GAAGGGCCTT GTCCCATTCA CGGCAGAGTC ACTTGAACTT 
ATAAAAAATC ACATTGCTAA AAAATGCAAC GAAGAGCATG AAGAAGAAGA TTTAAAACCA 
AGCCGGGATA TAGAAGCAGG CAAAAAACTT CCATTTGCCT ATGGAACCCT TCCTCAAGGA 
ACCGTGTCAG AGCCCTTGGA AGATGTGGAT CCATACTACT ATGTTAAGAG AAATACTTTC 
ATGGTCTTAA ACAGAAACAG AGTCATCTTC AGGTTCAATG CGGTTTCCAT CCTCTGCACG 
TTGTCTCCTT TAAGCTCTCT CAGAAGAGCT GTTATCAAGG TTTTGGTGCA CCCCCTTTTG 
CGCCTGCTGA TTTTAATTAG TGTTCTCACC GACAGCATAC TTATGTGCAT GAGTAACCTA 
CCGGAATGGA TATTGGCAGT AGAGAATACT TGCTTGGGAA TTTACACATT CGAAATACTG 
GTAAAAGTCA TTGCAAGAGG TATCTGGGCA GGGTCATTTT CCTTCCTTGG GGATCTTTGG 
AACTGGCTTG ATTTCAGTGT AACTTTGTTC GAGCTTATCA CAAGGTCTTC ACCTCTAAGC 
TCCCTTCCAA TGTTTAAAAC AATAAGAACC TTGCGAATTT TGAAGATCAT CCCTTTGAAC 
CATGGCCTGC AGTCTATTGT GGTGACGCTG GTCCAGTGTT TGAAGAAACT ACTCGGAGCC 
ATTGCCCTAG CTCTGTTTTT TCTGACTGTG TCTTCGCTAT TCGGGATGGG TCTCTTCATG 
GGCAACCTGA AGCACAAATG TGTGCGATGG CCCCAAGAAG ATGGAAATGA TGTGATGTAC 
AGTGGAACTG GAAGCCAGTA CCATATTCTA GAAAGAGAAA ACTTCTACTA TATGGAAGGC 
GCGAGATACG CTCTCCTCTG CGGCAACAAG ACAGATGCCG GCCTGTGTCC AGAAGGTTAT 
ATGTGTGTAA AAGAGGGCTC AAATCCTGAC AATGGCTTCA CAAGTTTTGA CAATTTTGGC 
TGGGCTCTAC TGGCTATGTT TCGATTGATG ACTCAGGATT ACCCTGAATT ACTTTATCAC 
CAGATCCTTT ATGCTTCAGG AAAGATCTAC ATGATATTTT TTGTTCTGAT CAGTTTCTGG 
TTTGCCTTCT ATATGGCAAG TTTGTTCTTG GGCATCCTCA CTATGGCCTA TGAACAGGAG 
AAGCAGAGAG CTTCTGAGGA GTCTAGAGAC ATGGATTCTA AATGTCATCA GACTGTGAAA 
GAATTCGAGG AAGAACATGA AGGAGCTGAG CTTCAGTGTA TCTGGTTTTA TGAGGAGGTT 
CTTGATCTAC TTGGACTTGA GCTTTGTATC AAGGAGATGG AAACTACACA AATAGAAATG 
AAGAAAAGAT CACCAACTTC TATAAACACC ACATTGGATA TACTGGAAGA CACTGCCCTT 
GGACACAAAG AAGAACCAGA AACATCCAGG AAGGAATGCC CACTCTGTTG GTATAAGTTT 
ACTAAAACCT GCTTTATCTG GAAATGCTCT CCCTGTTGGA TAAAACTGAA TGAGTTTGCT 
GACAGAATTA TAACACACCC ATTGTTTGAT CTTTTCCTTG TTATATGCAT CATTTTAAAC 
ATATGCTTCC TGGCCCTAGA ACACTTTCCA ATGAGTGAGG AGCTCATGTC ACTCCTTGCC 
ATTGGAAACT TGGTTTTTAT TGGAATTTAC ACAATAGAAA TGATTTTGAA GATAATCGCT 
ATGCATCCAT ATGGGTATTT CCAAATAAGC TGGCATATTT TTGACAGTAT TCTTGTGGTT 
TTGGGATTAA CAGAAATGTT ACTAGCAGAT ATTGAAGAAA TAACTGTTTT TATATTAGTC 
CCATTGATAT TTATAAAATT GGGAAAATAT GCACCACCAT TTAAGAATTT GATGCGTATT 
CTTGGTAGAG CATTGGTGGC CCTGAAAGAC TTGGTCCTGT TGGTCTCCAT TTTCATTTAC 
TTCTCTGCCG TGTTTGGCAT GAAGCTGTTT GGTCGAAGTT ACAAAGATTG TGTCTGCCAC 
GTAGATCAAG ACTGTCAACG CCAACGTTGG CACATGAGTG ACTTCCTCCA CGCCTACGTG 
ACTGTGTTCC GAATCCTCTG CGGAGAGTGG ATAGAGACAT TATGGGAGTG TATGGAGGTT 
GCAGGCGAGG CCTGGTGTAT TCCATTTTAC ATGATGGTCA TTTTAATTGG AAATTTATTG 
ATACTTTACC TCTTTGTGGG ATTGGTGAGC TCATTTGCTT CATACGATGC TACCACAGAA 
GTGAGCAAAG AAGCCAAAAA CCTTCAGCTT GCAGTGGCAT GGATAAAAAT GGTAATAAAC 
TGTGTGCTTC TTAAAATACT GTGCAAAGAA AAAACTGTTT CTACAGAAGC AACAGACCAA 
ACATGTGATC CAAGTGTTAA AGAGAATATT TCTGGTCATA CTCTTTCTGA ACTGAGCAAC 
ACCCAAACAT TCCTCAGATA CAAGGACCAG AGCAGTGGTA CTGAGAAAAC TCCAGTGACT 
GAGTCTGAGA GCCAATCCCT GATTGCTAGT CCCAGTGTAT CAGAAACTGT GCCAATTGCT 
TCAGGAGAAT CCGATATAGA AAACCTGGAT AACAAGGAGA CTCGGAGCAA GTCTGCAAAT 
GGAAGCAGTA AAGAGAAAAT GAAGCAATCT AGTTCATCTG AGTGCAGCAC GGTTGATATT 
GCTATTTCTG AAGAAGAAGA AATGGTCTAT GAACATGAAA AGTCGAAGCT TCATAAAAAT 
GGTTATGAAC GCAAATCTTC AGCTGGCCAA GTCAGTAGAG AATCTAGGAA TGGAAAGATT 
TGGAGGAACA TAAGGAAAAC TTGCTGCAAG ATAGTGGAGA ACAGCTGGTT TGAGTGTTTC 
ATTGGCCTGG TCACTCTGCT CTGCACAGGC ACTCTGGCTC TGGAAGACAT ATATATTCAT 
CAGCGGAAAA CCATTAAAAT CTTCCTGGAG TATGGAGACA TGATATTTGC TTACATCTTC 
ATTCTGGAGA TGCTTCTCAA GTGGGTGGCC TACGGCTTTA AAGCCTACTT CTCTAACAAC 
TGGTACAAGC TGGACTTCAT GGTCGTTATC GTGTTGTGTC TTAGCTTAAA AGGCAAAACT 
CGAGAGGACC TGAACCCTCT GCCTTCCATA AAGTTCCTTC GAGCACTTAG AGTTCTGTCT 
CAGTTTGAAA GAATGAAGGT GGTTCTGAGA GCTTTGATAA AAACAACCTT ACCCGCTGTG 
AGCGTGTTTC TGGTCTGCCT AATGATCTGG CTGCTTTTCA GTGTTATGGG AGTGTTCTTA 
TTCGCTGGCA AGTTCTATGA ATGCATTGAC CCAACAAGGG GAGAAAGATT CTCTGTATTT 
GAAGTTATGA ATAAGAGTCA GTGTGAAAAC CTGGTATTTA ATGAATCAAT GCCATGGGAG 
AATGCAAAAC TGAACTTTGA TAATGTTGGA AATGGTTTTC TTTCTTTGTT CCAAGTGGCA 
ACATTTAATG GGTGGATCAG TATTATGAAT TCAGCAATTG ACTCTGTTGG TGTGTACATG 
CAGCCTAGTT TTGAGCACAG CCTCCACATG TACACTTACT TTATCATCTT TGTTGTGTTT 
GGATTATTTC TTCCCTTGTG TATGCTGATT GGTGTTATTA TCAGGAATTT CAACAAGCAG 
AAAATTAAGC AGGGAGGATC AAATATCTTT ATAACGGTAA AGCAGAAGAA GCAGTACCGG 
GCACTGAAGA AGCTCTTGTA TGCAGACTCT CAGAAACCAG CAGCCCGCCC TAGAAACAAG 
TTCCAAGGCT TCATTTGTGA CGTAGTAACA CATCGTGTCT TTAATGTCGT CGTCGTACTT 
CTTATCTGTT TCCAAGCAAC AACCATTATG ATACAAAATG ATGAGCAGAG TCCACAAATT 
GAAACCGCTG TCTTCTGGAT GAACTCCCTT TTTACCATGC TGTTCACTCT GGAATGCATA 
CTGAAGCTCA CCGCCTTCCG CTGCCACTAT TTCACCAGCG CATGGAATGT TCATGACTTT 
ATGGTGGTCG TTTTCTCCAT TACAGGACTG CTGCTGCCTT TGTCAATAGG ACAATACTTT 
GTGCCTCCTT CACTGGTGCA GCTGCTTCTT CTCTCTCGCA TCATCCATGT CCTGCGTCCT 
GGGAAAGGAC CAAAGGTGTT CCATGATCTG ATGCTTCCCT TGATGCTGTC ACTCCCAGCA 
CTGCTCAACA TTGGTCTTCT CATCTTCCTG GTCATGTTCA TCTACGCCAT CTTTGGAATG 
TACAACTTCG CCTACGTGAA GAAAGAAGCC GGAATTAATG ATGTGTCCAA CTTTGAGACC 
TTTGGAAGCA GTATGCTTTG TCTCTTTCAA GTTACAACAT TTTCTGGTTG GGACGGGATG 
CTGGATGCAA TTTTCAACAG TCAGTGGTCT GACTGCGATC CTGATAAAAT TAACCCAGGG 
ACTCAGGTCA GGGGAGACTG TGGGAGCCCT TCTGTTGGGA TTTTTTATTT TGTCAGTTAC 
ATCCTCATAT CATGGTTGAT CATTGTTAAT ATGTACGTTG TTTTGATCAT GGAGTTCTTA 
AGTATTCCTT CTAAGAGAAA AAACAGGACC TTGAGCGAAG ATGACTTTAG GAGATTCTTC 
AAGGTATGGA ACAGGTTTGA CCCTGACAGG ACCCAGTACA TAGACTCTAC TAAGCTTTCT 
GATTTTGCAG CTGCTCTCGA TCCTCCTCTT TTCATGGCAA AACCAAACAA GGGCCAGCTT 
GTAGCCATGG ATCTCCCCAT GGCTGCAGGA GACAGAATCC ATTGCCTTGA TATTTTGCTT 
GCCTTTACGA AAAGAGTGAT GGGAAAGGAT GAGCGGGTGG AGAAGATCCT TTCAGAGATA 
GAATCTGGGT TTATGTTAGC GAACCCTTTC AAAATTACGT ATGAGCCGAT TACAACGACT 
TTGAAACGCA AACAAGAGGC AGTCTCAGCC ACTATCATCC AGCGGGCATA CAAAAGTTAC 
CGCTTAAGGC AAAGTGACAA AAAGATACAA GATATCCCGG AAATAGATGA TGGCAGGGAG 
GATCCTAACT CTAAAGGTGT CCACTCTGGT CAAATCGAGG AAAAGGCATC TATTCAGACC 
CAGATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scn7a ( XM_006234296.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234358.1 Rattus norvegicus sodium voltage-gated channel alpha subunit 7 (Scn7a), transcript variant X1, mRNA.

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CloneID	ORa25921
Clone ID Related Accession (Same CDS sequence)	XM_006234296.3
Accession Version	XM_006234296.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5043bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	sodium channel protein type 7 subunit alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234296.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACTT CGCCAGAGCC GAAGGGCCTT GTCCCATTCA CGGCAGAGTC ACTTGAACTT 
ATAAAAAATC ACATTGCTAA AAAATGCAAC GAAGAGCATG AAGAAGAAGA TTTAAAACCA 
AGCTGGGGTT TAGAAGCAGG CAAAAAACTT CCATTTGCCT ATGGAACCCT TCCTCAAGGA 
ACCGTGTCAG AGCCCTTGGA AGATGTGGAT CCATACTACT ATGTTAAGAG AAATACTTTC 
ATGGTCTTAA ACAGAAACAG AGTCATCTTC AGGTTCAATG CGGTTTCCAT CCTCTGCACG 
TTGTCTCCTT TAAGCTCTCT CAGAAGAGCT GTTATCAAGG TTTTGGTGCA CCCCCTTTTT 
CGCCTGCTGA TTTTAATTAG TGTTCTCACC GACAGCATAC TTATGTGCAT GAGTAATCTA 
CCGGAATGGA TATTGGCAGT AGAGAATACT TTGCTTGGGA TTTACACATT CGAAATACTT 
GTAAAAGTCA TTGCAAGAGG TATCTGGGCA GGGTCATTTT CCTTCCTTGG GGATCTTTGG 
AACTGGCTTG ATTTCAGTGT AACTTTGTTC GAGCTTATCA CAAGGTCTTC ACCTCTAAGC 
TCCCTTCCAA TGTTTAAAAC AATAAGAACC TTGCGAATTT TGAAGATCAT TCCTTTGAAC 
CATGGCCTGC AGTCTATTGT GGTGACGCTG GTCCAGTGTT TGAAGAAACT ACTCGGAGCC 
ATTGCCCTAG CTCTGTTTTT TCTGACTGTG TCTTCGCTAT TCGGGATGGG TCTCTTCATG 
GGCAACCTGA AGCACAAATG TGTGCGATGG CCCCAAGAAG ATGGAAATGA TGTGATGTAC 
AATGGAACTG GAAGCCAGTA CCATATTCTA GAAAGAGAAA ACTTCTACTA TATGGAAGGC 
GCGAGATACG CTCTCCTCTG CGGCAACAAG ACAGATGCCG GCCTGTGTCC AGAAGGTTAT 
ATGTGTGTAA AAGAGGGCTC AAATCCTGAC AATGGCTTCA CAAGTTTTGA CAATTTTGGC 
TGGGCTCTAC TGGCTATGTT TCGATTGATG ACTCAGGATT ACCCTGAATT ACTTTATCAC 
CAGATCCTTT ATGCTTCAGG AAAGATCTAC ATGATATTTT TTGTTCTGAT CAGTTTCTGG 
TTTGCCTTCT ATATGGCAAG TTTGTTCTTG GGCATCCTCA CTATGGCCTA TGAACAGGAG 
AAGCAGAGAG CTTCTGAGGA GTCTAGAGAC ATGGATTCTA AATGTCATCA GACTGTGAAA 
GAATTCGAGG AAGAACATGA AGGAGCTGAG ATGGAAACTA CACAAATAGA AATGAAGAAA 
AGATCACCAA CCTCTATAAA CACCACATTG GATATACTGG AAGACACTGC CCTTGGACAC 
AAAGAAGAAC CAGAAACATC CAGGAAGGAA TGCCCACTCT GTTGGTATAA GTTTACTAAA 
ACCTGCTTTA TCTGGAAATG CTCTCCCTGT TGGATAAAAC TGAATGAGTT TGCTGACAGA 
ATTATAACAC ACCCATTGTT TGATCTTTTC CTTGTTATAT GCATCATTTT AAACATATGC 
TTCCTGGCCC TAGAACACTT TCCAATGAGT GAGGAGCTCA TGTCACTCCT TGCCATTGGA 
AACTTGGTTT TTATTGGAAT TTACACAATA GAAATGATTT TGAAGATAAT CGCTATGCAT 
CCATATGGGT ATTTCCAAAT AAGCTGGCAT ATTTTTGACA GTATTCTTGT GGTTTTGGGA 
TTAACAGAAA TGTTACTAGC AGATATTGAA GAAATAACTG TTTTTATATT AGTCCCATTG 
ATATTTATAA AATTGGGAAA ATATGCACCA CCATTTAAGA ATTTGATGCG TATTCTTGGT 
AGAGCATTGG TGGCCCTGAA AGACTTGGTC CTGTTGGTCT CCATTTTCAT TTACTTCTCT 
GCCGTGTTTG GCATGAAGCT GTTTGGTCGA AGTTACAAAG ATTGTGTCTG CCACGTAGAT 
CAAGACTGTC AACGCCAACG TTGGCACATG AGTGACTTCC TCCACGCCTA CGTGACTGTG 
TTCCGAATCC TCTGCGGAGA GTGGATAGAG ACATTATGGG AGTGTATGGA GGTTGCAGGC 
GAGGCCTGGT GTATTCCATT TTACATGATG GTCATTTTAA TTGGAAATTT ATTGATACTT 
TACCTCTTTG TGGCATTGGT GAGCTCATTT GCTTCATACG ATGCTACCAC AGAAGTGAGC 
AAAGAAGCCA AAAACCTTCA GCTTGCAGTG GCATGGATAA AAATGGTAAT AAACTGTGTG 
CTTCTTAAAA TACTGTGCAA AGAAAAAACT GTTTCTACAG AAGCAACAGA CCAAACATGT 
GATCCAAGTG TTAAAGAGAA TATTTCTGGT CATACTCTTT CTGAACTGAG CAACACCCAA 
ACATTCCTCA GATACAAGGA CCAGAGCAGT GGTACTGAGA AAACTCCAGT GACTGAGTCT 
GAGAGCCAAT CCCTGATTGC TAGTCCCAGT GTATCAGAAA CTGTGCCAAT TGCTTCAGGA 
GAATCCGATA TAGAAAACCT GGATAACAAG GAGACTCGGA GCAAGTCTGC AAATGGAAGC 
AGTAAAGAGA AAATGAAGCA ATCTAGTTCA TCTGAGTGCA GCACGGTTGA TATTGCTATT 
TCTGAAGAAG AAGAAATGGT CTATGAACAT GAAAAGTCGA AGCTTCATAA AAATGGTTAT 
GAACGCAAAT CTTCAGCTGG CCAAGTCAGT AGAGAATCTA GGAATGGAAA GATTTGGAGG 
AACATAAGGA AAACTTGCTG CAAGATAGTG GAGAACAGCT GGTTTGAGTG TTTCATTGGC 
CTGGTCACTC TGCTCTGCAC AGGCACTCTG GCTCTGGAAG ACATATATAT TGATCAGCGG 
AAAACCATTA AAATCTTCCT GGAGTATGGA GACATGATAT TTGCTTACAT CTTCATTCTG 
GAGATGCTTC TCAAGTGGGT GGCCTACGGC TTTAAAGCCT ACTTCTCTAA CAACTGGTAC 
AAGCTGGACT TCATGGTCGT TATCGTGTTG TGTCTTAGCT TAATAGGCAA AACTCGAGAG 
GACCTGAACC CTCTGGCTTC CATAAAGTTC CTTCGAGCAC TTAGAGTTCT GTCTCAGTTT 
GAAAGAATGA AGGTGGTTCT GAGAGCTTTG ATAAAAACAA CCTTACCCGC TGTGAGCGTG 
TTTCTGGTCT GCCTAATGAT CTGGCTGCTT TTCAGTGTTA TGGGAGTGTT CTTATTCGCT 
GGCAAGTTCT ATGAATGCAT TGACCCAACA AGGGGAGAAA GATTCTCTGT ATTTGAAGTT 
ATGAATAAGA GTCAGTGTGA AAACCTGGTA TTTAATGAAT CAATGCCATG GGAGAATGCA 
AAACTGAACT TTGATAATGT TGGAAATGGT TTTCTTTCTT TGTTCCAAGT GGCAACATTT 
AATGGGTGGA TCAGTATTAT GAATTCAGCA ATTGACTCTG TTGGTGTGTA CATGCAGCCT 
AGTTTTGAGC ACAGCCTCCA CATGTACACT TACTTTATCA TCTTTGTTGT GTTTGGATTA 
TTTCTTCCCT TGTGTATGCT GATTGGTGTT ATTATCAGGA ATTTCAACAA GCAGAAAATT 
AAGCAGGGAG GATCAAATAT CTTTATAACG GTAAAGCAGA AGAAACAGTA CCGGGCACTG 
AAGAAGCTCT TGTATGCAGA CTCTCAGAAA CCAGCAGCCC GCCCTAGAAA CAAGTTCCAA 
GGCTTCATTT GTGACGTAGT AACACATCGT GTCTTTAATG TCATCATCAT ACTTCTTATC 
TGTTTCCAAG CAACAACCAT TATGATACAA AATGATGAGC AGAGTCCACA AATTGAAACC 
GCTGTCTTCT GGATGAACTC CCTTTTTACC ATGCTGTTCA CTCTGGAATG CATACTGAAG 
CTCACCGCCT TCCGCTGCCA CTATTTCACC AGCGCATGGA ATGTTCATGA CTTTATGGTG 
GTCGTTTTCT CCATTACAGG ACTGCTGCTG CCTTTGTCAA TAGGACAATA CTTTGTGCCT 
CCTTCACTGG TGCAGCTGCT TCTTCTCTCT CGCATCATCC ATGTCCTGCG TCCTGGGAAA 
GGACCAAAGG TGTTCCATGA TCTGATGCTT CCCTTGATGC TGTCACTCCC AGCACTGCTC 
AACATTGCTC TTCTCATCTT CCTGGTCATG TTCATCTACG CCATCTTTGG AATGTACAAC 
TTCGCCTACG TAAAGAAAGA AGCCGGAATT AATGATGTGT CCAACTTTGA GACCTTTGGA 
AGCAGTATGC TTTGTCTCTT TCAAGTTACA ACATTTTCTG GTTGGGACGG GATGCTGGAT 
GCAATTTTCA ACAGTCAGTG GTCTGACTGC GATCCTGATA AAATTAACCC AGGGACTCAG 
GTCAGGGGAG ACTGTGGGAG CCCTTCTGTT GGGATTTTTT ATTTTGTCAG TTACATCCTC 
ATATCATGGT TGATCATTGT TAATATGTAC GTTGTTTTGA TCATGGAGTT CTTAAGTATT 
CCTTCTAAGA GAAAAAACAG GACCTTGAGC GAAGATGACT TTAGGAGATT CTTCAAGGTA 
TGGAACAGGT TTGACCCTGA CAGGACCCAG TACATAGACT CTACTAAGCT TTCTGATTTT 
GCAGCTGCTC TCGATCCTCC TCTTTTCATG GCAAAACCAA ACAAGGGCCA GCTTGTAGCC 
ATGGATCTCC CCATGGCTGC AGGAGACAGA ATCCATTGCC TTGATATTTT GCTTGCCTTT 
ACGAAAAGAG TGATGGGAAA GGATGAGCGG GTGGAGAAGA TCCTTTCAGA GATAGAATCT 
GGGTTTATGT TAGCGAACCC TTTCAAAATT ACGTATGAGC CGATTACAAC GACTTTGAAA 
CGCAAACAAG AGGCAGTCTC AGCCACTATC ATCCAGCGGG CATACAAAAG TTACCGCTTA 
AGGCAAAGTG ACAAAAAGAT ACAAGATATC CCGGAAATAG ATGATGGCAG GGAGGATCCT 
AACTCTAAAG GTGTCCACTC TGGTCAAATC GAGGAAAAGG CATCTATTCA GACCCAGATC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234358.1
CDS	334..5376
Translation	MLTSPEPKGLVPFTAESLELIKNHIAKKCNEEHEEEDLKPSWGLEAGKKLPFAYGTLPQGTVSEPLEDVDPYYYVKRNTFMVLNRNRVIFRFNAVSILCTLSPLSSLRRAVIKVLVHPLFRLLILISVLTDSILMCMSNLPEWILAVENTLLGIYTFEILVKVIARGIWAGSFSFLGDLWNWLDFSVTLFELITRSSPLSSLPMFKTIRTLRILKIIPLNHGLQSIVVTLVQCLKKLLGAIALALFFLTVSSLFGMGLFMGNLKHKCVRWPQEDGNDVMYNGTGSQYHILERENFYYMEGARYALLCGNKTDAGLCPEGYMCVKEGSNPDNGFTSFDNFGWALLAMFRLMTQDYPELLYHQILYASGKIYMIFFVLISFWFAFYMASLFLGILTMAYEQEKQRASEESRDMDSKCHQTVKEFEEEHEGAEMETTQIEMKKRSPTSINTTLDILEDTALGHKEEPETSRKECPLCWYKFTKTCFIWKCSPCWIKLNEFADRIITHPLFDLFLVICIILNICFLALEHFPMSEELMSLLAIGNLVFIGIYTIEMILKIIAMHPYGYFQISWHIFDSILVVLGLTEMLLADIEEITVFILVPLIFIKLGKYAPPFKNLMRILGRALVALKDLVLLVSIFIYFSAVFGMKLFGRSYKDCVCHVDQDCQRQRWHMSDFLHAYVTVFRILCGEWIETLWECMEVAGEAWCIPFYMMVILIGNLLILYLFVALVSSFASYDATTEVSKEAKNLQLAVAWIKMVINCVLLKILCKEKTVSTEATDQTCDPSVKENISGHTLSELSNTQTFLRYKDQSSGTEKTPVTESESQSLIASPSVSETVPIASGESDIENLDNKETRSKSANGSSKEKMKQSSSSECSTVDIAISEEEEMVYEHEKSKLHKNGYERKSSAGQVSRESRNGKIWRNIRKTCCKIVENSWFECFIGLVTLLCTGTLALEDIYIDQRKTIKIFLEYGDMIFAYIFILEMLLKWVAYGFKAYFSNNWYKLDFMVVIVLCLSLIGKTREDLNPLASIKFLRALRVLSQFERMKVVLRALIKTTLPAVSVFLVCLMIWLLFSVMGVFLFAGKFYECIDPTRGERFSVFEVMNKSQCENLVFNESMPWENAKLNFDNVGNGFLSLFQVATFNGWISIMNSAIDSVGVYMQPSFEHSLHMYTYFIIFVVFGLFLPLCMLIGVIIRNFNKQKIKQGGSNIFITVKQKKQYRALKKLLYADSQKPAARPRNKFQGFICDVVTHRVFNVIIILLICFQATTIMIQNDEQSPQIETAVFWMNSLFTMLFTLECILKLTAFRCHYFTSAWNVHDFMVVVFSITGLLLPLSIGQYFVPPSLVQLLLLSRIIHVLRPGKGPKVFHDLMLPLMLSLPALLNIALLIFLVMFIYAIFGMYNFAYVKKEAGINDVSNFETFGSSMLCLFQVTTFSGWDGMLDAIFNSQWSDCDPDKINPGTQVRGDCGSPSVGIFYFVSYILISWLIIVNMYVVLIMEFLSIPSKRKNRTLSEDDFRRFFKVWNRFDPDRTQYIDSTKLSDFAAALDPPLFMAKPNKGQLVAMDLPMAAGDRIHCLDILLAFTKRVMGKDERVEKILSEIESGFMLANPFKITYEPITTTLKRKQEAVSATIIQRAYKSYRLRQSDKKIQDIPEIDDGREDPNSKGVHSGQIEEKASIQTQI

Target ORF information:

RefSeq Version	XM_006234296.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sodium voltage-gated channel alpha subunit 7 (Scn7a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234296.3

ORF Insert Sequence:

ATGTTGACTT CGCCAGAGCC GAAGGGCCTT GTCCCATTCA CGGCAGAGTC ACTTGAACTT 
ATAAAAAATC ACATTGCTAA AAAATGCAAC GAAGAGCATG AAGAAGAAGA TTTAAAACCA 
AGCTGGGGTT TAGAAGCAGG CAAAAAACTT CCATTTGCCT ATGGAACCCT TCCTCAAGGA 
ACCGTGTCAG AGCCCTTGGA AGATGTGGAT CCATACTACT ATGTTAAGAG AAATACTTTC 
ATGGTCTTAA ACAGAAACAG AGTCATCTTC AGGTTCAATG CGGTTTCCAT CCTCTGCACG 
TTGTCTCCTT TAAGCTCTCT CAGAAGAGCT GTTATCAAGG TTTTGGTGCA CCCCCTTTTT 
CGCCTGCTGA TTTTAATTAG TGTTCTCACC GACAGCATAC TTATGTGCAT GAGTAATCTA 
CCGGAATGGA TATTGGCAGT AGAGAATACT TTGCTTGGGA TTTACACATT CGAAATACTT 
GTAAAAGTCA TTGCAAGAGG TATCTGGGCA GGGTCATTTT CCTTCCTTGG GGATCTTTGG 
AACTGGCTTG ATTTCAGTGT AACTTTGTTC GAGCTTATCA CAAGGTCTTC ACCTCTAAGC 
TCCCTTCCAA TGTTTAAAAC AATAAGAACC TTGCGAATTT TGAAGATCAT TCCTTTGAAC 
CATGGCCTGC AGTCTATTGT GGTGACGCTG GTCCAGTGTT TGAAGAAACT ACTCGGAGCC 
ATTGCCCTAG CTCTGTTTTT TCTGACTGTG TCTTCGCTAT TCGGGATGGG TCTCTTCATG 
GGCAACCTGA AGCACAAATG TGTGCGATGG CCCCAAGAAG ATGGAAATGA TGTGATGTAC 
AATGGAACTG GAAGCCAGTA CCATATTCTA GAAAGAGAAA ACTTCTACTA TATGGAAGGC 
GCGAGATACG CTCTCCTCTG CGGCAACAAG ACAGATGCCG GCCTGTGTCC AGAAGGTTAT 
ATGTGTGTAA AAGAGGGCTC AAATCCTGAC AATGGCTTCA CAAGTTTTGA CAATTTTGGC 
TGGGCTCTAC TGGCTATGTT TCGATTGATG ACTCAGGATT ACCCTGAATT ACTTTATCAC 
CAGATCCTTT ATGCTTCAGG AAAGATCTAC ATGATATTTT TTGTTCTGAT CAGTTTCTGG 
TTTGCCTTCT ATATGGCAAG TTTGTTCTTG GGCATCCTCA CTATGGCCTA TGAACAGGAG 
AAGCAGAGAG CTTCTGAGGA GTCTAGAGAC ATGGATTCTA AATGTCATCA GACTGTGAAA 
GAATTCGAGG AAGAACATGA AGGAGCTGAG ATGGAAACTA CACAAATAGA AATGAAGAAA 
AGATCACCAA CCTCTATAAA CACCACATTG GATATACTGG AAGACACTGC CCTTGGACAC 
AAAGAAGAAC CAGAAACATC CAGGAAGGAA TGCCCACTCT GTTGGTATAA GTTTACTAAA 
ACCTGCTTTA TCTGGAAATG CTCTCCCTGT TGGATAAAAC TGAATGAGTT TGCTGACAGA 
ATTATAACAC ACCCATTGTT TGATCTTTTC CTTGTTATAT GCATCATTTT AAACATATGC 
TTCCTGGCCC TAGAACACTT TCCAATGAGT GAGGAGCTCA TGTCACTCCT TGCCATTGGA 
AACTTGGTTT TTATTGGAAT TTACACAATA GAAATGATTT TGAAGATAAT CGCTATGCAT 
CCATATGGGT ATTTCCAAAT AAGCTGGCAT ATTTTTGACA GTATTCTTGT GGTTTTGGGA 
TTAACAGAAA TGTTACTAGC AGATATTGAA GAAATAACTG TTTTTATATT AGTCCCATTG 
ATATTTATAA AATTGGGAAA ATATGCACCA CCATTTAAGA ATTTGATGCG TATTCTTGGT 
AGAGCATTGG TGGCCCTGAA AGACTTGGTC CTGTTGGTCT CCATTTTCAT TTACTTCTCT 
GCCGTGTTTG GCATGAAGCT GTTTGGTCGA AGTTACAAAG ATTGTGTCTG CCACGTAGAT 
CAAGACTGTC AACGCCAACG TTGGCACATG AGTGACTTCC TCCACGCCTA CGTGACTGTG 
TTCCGAATCC TCTGCGGAGA GTGGATAGAG ACATTATGGG AGTGTATGGA GGTTGCAGGC 
GAGGCCTGGT GTATTCCATT TTACATGATG GTCATTTTAA TTGGAAATTT ATTGATACTT 
TACCTCTTTG TGGCATTGGT GAGCTCATTT GCTTCATACG ATGCTACCAC AGAAGTGAGC 
AAAGAAGCCA AAAACCTTCA GCTTGCAGTG GCATGGATAA AAATGGTAAT AAACTGTGTG 
CTTCTTAAAA TACTGTGCAA AGAAAAAACT GTTTCTACAG AAGCAACAGA CCAAACATGT 
GATCCAAGTG TTAAAGAGAA TATTTCTGGT CATACTCTTT CTGAACTGAG CAACACCCAA 
ACATTCCTCA GATACAAGGA CCAGAGCAGT GGTACTGAGA AAACTCCAGT GACTGAGTCT 
GAGAGCCAAT CCCTGATTGC TAGTCCCAGT GTATCAGAAA CTGTGCCAAT TGCTTCAGGA 
GAATCCGATA TAGAAAACCT GGATAACAAG GAGACTCGGA GCAAGTCTGC AAATGGAAGC 
AGTAAAGAGA AAATGAAGCA ATCTAGTTCA TCTGAGTGCA GCACGGTTGA TATTGCTATT 
TCTGAAGAAG AAGAAATGGT CTATGAACAT GAAAAGTCGA AGCTTCATAA AAATGGTTAT 
GAACGCAAAT CTTCAGCTGG CCAAGTCAGT AGAGAATCTA GGAATGGAAA GATTTGGAGG 
AACATAAGGA AAACTTGCTG CAAGATAGTG GAGAACAGCT GGTTTGAGTG TTTCATTGGC 
CTGGTCACTC TGCTCTGCAC AGGCACTCTG GCTCTGGAAG ACATATATAT TGATCAGCGG 
AAAACCATTA AAATCTTCCT GGAGTATGGA GACATGATAT TTGCTTACAT CTTCATTCTG 
GAGATGCTTC TCAAGTGGGT GGCCTACGGC TTTAAAGCCT ACTTCTCTAA CAACTGGTAC 
AAGCTGGACT TCATGGTCGT TATCGTGTTG TGTCTTAGCT TAATAGGCAA AACTCGAGAG 
GACCTGAACC CTCTGGCTTC CATAAAGTTC CTTCGAGCAC TTAGAGTTCT GTCTCAGTTT 
GAAAGAATGA AGGTGGTTCT GAGAGCTTTG ATAAAAACAA CCTTACCCGC TGTGAGCGTG 
TTTCTGGTCT GCCTAATGAT CTGGCTGCTT TTCAGTGTTA TGGGAGTGTT CTTATTCGCT 
GGCAAGTTCT ATGAATGCAT TGACCCAACA AGGGGAGAAA GATTCTCTGT ATTTGAAGTT 
ATGAATAAGA GTCAGTGTGA AAACCTGGTA TTTAATGAAT CAATGCCATG GGAGAATGCA 
AAACTGAACT TTGATAATGT TGGAAATGGT TTTCTTTCTT TGTTCCAAGT GGCAACATTT 
AATGGGTGGA TCAGTATTAT GAATTCAGCA ATTGACTCTG TTGGTGTGTA CATGCAGCCT 
AGTTTTGAGC ACAGCCTCCA CATGTACACT TACTTTATCA TCTTTGTTGT GTTTGGATTA 
TTTCTTCCCT TGTGTATGCT GATTGGTGTT ATTATCAGGA ATTTCAACAA GCAGAAAATT 
AAGCAGGGAG GATCAAATAT CTTTATAACG GTAAAGCAGA AGAAACAGTA CCGGGCACTG 
AAGAAGCTCT TGTATGCAGA CTCTCAGAAA CCAGCAGCCC GCCCTAGAAA CAAGTTCCAA 
GGCTTCATTT GTGACGTAGT AACACATCGT GTCTTTAATG TCATCATCAT ACTTCTTATC 
TGTTTCCAAG CAACAACCAT TATGATACAA AATGATGAGC AGAGTCCACA AATTGAAACC 
GCTGTCTTCT GGATGAACTC CCTTTTTACC ATGCTGTTCA CTCTGGAATG CATACTGAAG 
CTCACCGCCT TCCGCTGCCA CTATTTCACC AGCGCATGGA ATGTTCATGA CTTTATGGTG 
GTCGTTTTCT CCATTACAGG ACTGCTGCTG CCTTTGTCAA TAGGACAATA CTTTGTGCCT 
CCTTCACTGG TGCAGCTGCT TCTTCTCTCT CGCATCATCC ATGTCCTGCG TCCTGGGAAA 
GGACCAAAGG TGTTCCATGA TCTGATGCTT CCCTTGATGC TGTCACTCCC AGCACTGCTC 
AACATTGCTC TTCTCATCTT CCTGGTCATG TTCATCTACG CCATCTTTGG AATGTACAAC 
TTCGCCTACG TAAAGAAAGA AGCCGGAATT AATGATGTGT CCAACTTTGA GACCTTTGGA 
AGCAGTATGC TTTGTCTCTT TCAAGTTACA ACATTTTCTG GTTGGGACGG GATGCTGGAT 
GCAATTTTCA ACAGTCAGTG GTCTGACTGC GATCCTGATA AAATTAACCC AGGGACTCAG 
GTCAGGGGAG ACTGTGGGAG CCCTTCTGTT GGGATTTTTT ATTTTGTCAG TTACATCCTC 
ATATCATGGT TGATCATTGT TAATATGTAC GTTGTTTTGA TCATGGAGTT CTTAAGTATT 
CCTTCTAAGA GAAAAAACAG GACCTTGAGC GAAGATGACT TTAGGAGATT CTTCAAGGTA 
TGGAACAGGT TTGACCCTGA CAGGACCCAG TACATAGACT CTACTAAGCT TTCTGATTTT 
GCAGCTGCTC TCGATCCTCC TCTTTTCATG GCAAAACCAA ACAAGGGCCA GCTTGTAGCC 
ATGGATCTCC CCATGGCTGC AGGAGACAGA ATCCATTGCC TTGATATTTT GCTTGCCTTT 
ACGAAAAGAG TGATGGGAAA GGATGAGCGG GTGGAGAAGA TCCTTTCAGA GATAGAATCT 
GGGTTTATGT TAGCGAACCC TTTCAAAATT ACGTATGAGC CGATTACAAC GACTTTGAAA 
CGCAAACAAG AGGCAGTCTC AGCCACTATC ATCCAGCGGG CATACAAAAG TTACCGCTTA 
AGGCAAAGTG ACAAAAAGAT ACAAGATATC CCGGAAATAG ATGATGGCAG GGAGGATCCT 
AACTCTAAAG GTGTCCACTC TGGTCAAATC GAGGAAAAGG CATCTATTCA GACCCAGATC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Enhanced SCN7A/Nax expression contributes to bone cancer pain by increasing excitability of neurons in dorsal root ganglion.
Neuroscience22780-9(2012 Dec)
Ke CB,He WS,Li CJ,Shi D,Gao F,Tian YK

Impact of lactobacilli on orally acquired listeriosis.
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Archambaud C,Nahori MA,Soubigou G,B?cavin C,Laval L,Lechat P,Smokvina T,Langella P,Lecuit M,Cossart P

Voltage-gated sodium channel expression in rat spiral ganglion neurons.
Molecular and cellular neurosciences42(4)399-407(2009 Dec)
Fryatt AG,Vial C,Mulheran M,Gunthorpe MJ,Grubb BD

Sodium-level-sensitive sodium channel Na(x) is expressed in glial laminate processes in the sensory circumventricular organs.
American journal of physiology. Regulatory, integrative and comparative physiology290(3)R568-76(2006 Mar)
Watanabe E,Hiyama TY,Shimizu H,Kodama R,Hayashi N,Miyata S,Yanagawa Y,Obata K,Noda M

Specific Na+ sensors are functionally expressed in a neuronal population of the median preoptic nucleus of the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience24(16)3974-84(2004 Apr)
Grob M,Drolet G,Mouginot D

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Scn7a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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