Kcnab3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnab3
Entrez Gene ID	58981
Full Name	potassium voltage-gated channel subfamily A regulatory beta subunit 3
General protein information	Preferred Names potassium voltage-gated channel subfamily A regulatory beta subunit 3 Names voltage-gated potassium channel subunit beta-3 K(+) channel subunit beta-3 RCK beta3 kv-beta-3 potassium channel, voltage gated shaker-related subfamily A regulatory beta subunit 3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 potassium voltage gated channel, shaker related subfamily, beta member 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24
Summary	beta subunit of voltage gated potassium channel; involved in altering the activation kinetics of channel Kv1.4 [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017597493.1	XP_017452982.1	voltage-gated potassium channel subunit beta-3 isoform X1
NM_031652.1	NP_113840.1	voltage-gated potassium channel subunit beta-3

Pathways from BioSystems

Homologies

Homo sapiens (human)	KCNAB3	NP_004723.2
Bos taurus (cattle)	KCNAB3	NP_001075096.1
Rattus norvegicus (Norway rat)	Kcnab3	NP_113840.1
Xenopus tropicalis (tropical clawed frog)	kcnab3	NP_001072370.1
Pan troglodytes (chimpanzee)	KCNAB3	XP_001172327.2
Mus musculus (house mouse)	Kcnab3	NP_034729.3
	KCNAB3	XP_001111097.2
Canis lupus familiaris (dog)	KCNAB3	XP_546601.3
Danio rerio (zebrafish)	LOC100334158	XP_002662237.3

Gene Ontology
Bibliography

Related articles in PubMed

Functional effects of auxiliary beta4-subunit on rat large-conductance Ca(2+)-activated K(+) channel.
Ha TS, Heo MS, Park CS
Biophysical journal86(5)2871-82(2004 May)

Molecular and functional characterization of a rat brain Kv beta 3 potassium channel subunit.
Heinemann SH, Rettig J, Wunder F, Pongs O
FEBS letters377(3)383-9(1995 Dec)

Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit.
Rettig J, Heinemann SH, Wunder F, Lorra C, Parcej DN, Dolly JO, Pongs O
Nature369(6478)289-94(1994 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the auxiliary beta4-subunit has a function in rat large-conductance Ca(2+)-activated K(+) channel
Title: Functional effects of auxiliary beta4-subunit on rat large-conductance Ca(2+)-activated K(+) channel.

The following Kcnab3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnab3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08381	NM_031652.1 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily A regulatory beta subunit 3 (Kcnab3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa57461	XM_017597493.1 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily A regulatory beta subunit 3 (Kcnab3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnab3 ( NM_031652.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113840.1 Rattus norvegicus potassium voltage-gated channel subfamily A regulatory beta subunit 3 (Kcnab3), mRNA.

Price & Availability↑

CloneID	ORa08381
Clone ID Related Accession (Same CDS sequence)	NM_031652.1
Accession Version	NM_031652.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-07
Organism	Rattus norvegicus(Norway rat)
Product	voltage-gated potassium channel subunit beta-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X76723.1. ##Evidence-Data-START## Transcript exon combination :: X76723.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCAGGTGT CTATCGCGTG TACCGAGCAG AACCTTCGCA GCCGGAGCAG TGAGGACCGT 
CTCTGTGGAC CCCGGCCGGG TCCTGGAGGC GGTAATGGAG GGCCAGTGGG CGGAGGGCAT 
GGGAACCCTC CGGGGGGTGG AGGATTGGGC TCCAAGTCAC GGACTGCAGT GGTCCCCCGA 
CCCCCAGCAC CTGCTGGGGC CCTTCGAGAG AGCACCGGCC GAGGCACTGG CATGAAATAC 
AGGAACCTAG GAAAGTCTGG ACTCCGGGTG TCCTGTCTTG GCCTCGGAAC CTGGGTCACA 
TTTGGCTCTC AGATCTCAGA TGAGACAGCA GAAGATCTCC TGACAGTAGC CTATGAGCAC 
GGTGTAAACC TGTTTGACAC CGCTGAAGTG TACGCAGCAG GAAAGGCTGA AAGAACCCTA 
GGCAACATCC TCAAGAGCAA AGGTTGGAGG AGATCAAGCT ATGTTATCAC CACCAAGATT 
TTTTGGGGAG GACAGGCAGA AACTGAGCGA GGCTTGAGTC GCAAACACAT CATTGAAGGC 
TTGCAAGGAT CCCTGGACCG CCTCCAACTG GAATACGTTG ACATAGTATT TGCCAATCGT 
TCAGACCCCA GCAGTCCTAT GGAGGAGATT GTAAGAGCCA TGACCTATGT CATCAACCAG 
GGCCTGGCCC TATACTGGGG GACATCCAGG TGGAGTGCTG CAGAAATCAT GGAGGCCTAC 
TCCATGGCCA GACAGTTCAA TCTGATCCCT CCTGTGTGTG AACAAGCGGA GAACCACTTC 
TTTCAGAGGG AGAAGGTGGA GATGCAGCTG CCTGAGCTCT ACCACAAAAT TGGTGTTGGC 
TCAGTCACTT GGTCTCCCCT GGCGTGCAGC CTCATTACTA GCAAGTACGA TGGGCAAGTT 
CCAGATGCTT GCAAGGCCAC TGTCAAGGGC TACCAGTGGC TCAAAGAAAA AGTGCAAAGT 
GAAGATGGCA AGAAGCAACA AGCCAGAGTG ACGGACCTTC TCCCCATCGC TCACCAGCTA 
GGCTGCACCG TGGCCCAACT TGCTATAGCC TGGTGTCTCC GAAGCGAAGG TGTCAGCTCA 
GTTTTACTGG GGGTGTCCAG TGCAGAGCAG CTGATGGAAC ATCTGGGGTC CCTACAGGTG 
CTGGGTCAGC TGACGCCGCA AACGGTGATG GAAATAGATG CGCTCTTGGG GAACAAATCG 
CATTCCAAGA AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113840.1
CDS	388..1602
Translation	MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPVGGGHGNPPGGGGLGSKSRTAVVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDLLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLQGSLDRLQLEYVDIVFANRSDPSSPMEEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACSLITSKYDGQVPDACKATVKGYQWLKEKVQSEDGKKQQARVTDLLPIAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLGQLTPQTVMEIDALLGNKSHSKK

Target ORF information:

RefSeq Version	NM_031652.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily A regulatory beta subunit 3 (Kcnab3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031652.1

ORF Insert Sequence:

ATGCAGGTGT CTATCGCGTG TACCGAGCAG AACCTTCGCA GCCGGAGCAG TGAGGACCGT 
CTCTGTGGAC CCCGGCCGGG TCCTGGAGGC GGTAATGGAG GGCCAGTGGG CGGAGGGCAT 
GGGAACCCTC CGGGGGGTGG AGGATTGGGC TCCAAGTCAC GGACTGCAGT GGTCCCCCGA 
CCCCCAGCAC CTGCTGGGGC CCTTCGAGAG AGCACCGGCC GAGGCACTGG CATGAAATAC 
AGGAACCTAG GAAAGTCTGG ACTCCGGGTG TCCTGTCTTG GCCTCGGAAC CTGGGTCACA 
TTTGGCTCTC AGATCTCAGA TGAGACAGCA GAAGATCTCC TGACAGTAGC CTATGAGCAC 
GGTGTAAACC TGTTTGACAC CGCTGAAGTG TACGCAGCAG GAAAGGCTGA AAGAACCCTA 
GGCAACATCC TCAAGAGCAA AGGTTGGAGG AGATCAAGCT ATGTTATCAC CACCAAGATT 
TTTTGGGGAG GACAGGCAGA AACTGAGCGA GGCTTGAGTC GCAAACACAT CATTGAAGGC 
TTGCAAGGAT CCCTGGACCG CCTCCAACTG GAATACGTTG ACATAGTATT TGCCAATCGT 
TCAGACCCCA GCAGTCCTAT GGAGGAGATT GTAAGAGCCA TGACCTATGT CATCAACCAG 
GGCCTGGCCC TATACTGGGG GACATCCAGG TGGAGTGCTG CAGAAATCAT GGAGGCCTAC 
TCCATGGCCA GACAGTTCAA TCTGATCCCT CCTGTGTGTG AACAAGCGGA GAACCACTTC 
TTTCAGAGGG AGAAGGTGGA GATGCAGCTG CCTGAGCTCT ACCACAAAAT TGGTGTTGGC 
TCAGTCACTT GGTCTCCCCT GGCGTGCAGC CTCATTACTA GCAAGTACGA TGGGCAAGTT 
CCAGATGCTT GCAAGGCCAC TGTCAAGGGC TACCAGTGGC TCAAAGAAAA AGTGCAAAGT 
GAAGATGGCA AGAAGCAACA AGCCAGAGTG ACGGACCTTC TCCCCATCGC TCACCAGCTA 
GGCTGCACCG TGGCCCAACT TGCTATAGCC TGGTGTCTCC GAAGCGAAGG TGTCAGCTCA 
GTTTTACTGG GGGTGTCCAG TGCAGAGCAG CTGATGGAAC ATCTGGGGTC CCTACAGGTG 
CTGGGTCAGC TGACGCCGCA AACGGTGATG GAAATAGATG CGCTCTTGGG GAACAAATCG 
CATTCCAAGA AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnab3 ( XM_017597493.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452982.1 Rattus norvegicus potassium voltage-gated channel subfamily A regulatory beta subunit 3 (Kcnab3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa57461
Clone ID Related Accession (Same CDS sequence)	XM_017597493.1
Accession Version	XM_017597493.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	voltage-gated potassium channel subunit beta-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAACC TAGGAAAGTC TGGACTCCGG GTGTCCTGTC TTGGCCTCGG AACCTGGGTC 
ACATTTGGCT CTCAGATCTC AGATGAGACA GCAGAAGATC TCCTGACAGT AGCCTATGAG 
CACGGTGTAA ACCTGTTTGA CACCGCTGAA GTGTACGCAG CAGGAAAGGC TGAAAGAACC 
CTAGGCAACA TCCTCAAGAG CAAAGGTTGG AGGAGATCAA GCTATGTTAT CACCACCAAG 
ATTTTTTGGG GAGGACAGGC AGAAACTGAG CGAGGCTTGA GTCGCAAACA CATCATTGAA 
GGCTTGCAAG GATCCCTGGA CCGCCTCCAA CTGGAATACG TTGACATAGT ATTTGCCAAT 
CGTTCAGACC CCAGCAGTCC TATGGAGGAG ATTGTAAGAG CCATGACCTA TGTCATCAAC 
CAGGGCCTGG CCCTATACTG GGGGACATCC AGGTGGAGTG CTGCAGAAAT CATGGAGGCC 
TACTCCATGG CCAGACAGTT CAATCTGATC CCTCCTGTGT GTGAACAAGC GGAGAACCAC 
TTCTTTCAGA GGGAGAAGGT GGAGATGCAG CTGCCTGAGC TCTACCACAA AATTGGTGTT 
GGCTCAGTCA CTTGGTCTCC CCTGGCGTGC AGCCTCATTA CTAGCAAGTA CGATGGGCAA 
GTTCCAGATG CTTGCAAGGC CACTGTCAAG GGCTACCAGT GGCTCAAAGA AAAAGTGCAA 
AGTGAAGATG GCAAGAAGCA ACAAGCCAGA GTGACGGACC TTCTCCCCAT CGCTCACCAG 
CTAGGCTGCA CCGTGGCCCA ACTTGCTATA GCCTGGTGTC TCCGAAGCGA AGGTGTCAGC 
TCAGTTTTAC TGGGGGTGTC CAGTGCAGAG CAGCTGATGG AACATCTGGG CTCCCTACAG 
GTGCTGGGTC AGCTGACGCC GCAAACGGTG ATGGAAATAG ATGCGCTCTT GGGGAACAAA 
TCGCATTCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452982.1
CDS	168..1145
Translation	MLNLGKSGLRVSCLGLGTWVTFGSQISDETAEDLLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLQGSLDRLQLEYVDIVFANRSDPSSPMEEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACSLITSKYDGQVPDACKATVKGYQWLKEKVQSEDGKKQQARVTDLLPIAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLGQLTPQTVMEIDALLGNKSHSKK

Target ORF information:

RefSeq Version	XM_017597493.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily A regulatory beta subunit 3 (Kcnab3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597493.1

ORF Insert Sequence:

ATGCTGAACC TAGGAAAGTC TGGACTCCGG GTGTCCTGTC TTGGCCTCGG AACCTGGGTC 
ACATTTGGCT CTCAGATCTC AGATGAGACA GCAGAAGATC TCCTGACAGT AGCCTATGAG 
CACGGTGTAA ACCTGTTTGA CACCGCTGAA GTGTACGCAG CAGGAAAGGC TGAAAGAACC 
CTAGGCAACA TCCTCAAGAG CAAAGGTTGG AGGAGATCAA GCTATGTTAT CACCACCAAG 
ATTTTTTGGG GAGGACAGGC AGAAACTGAG CGAGGCTTGA GTCGCAAACA CATCATTGAA 
GGCTTGCAAG GATCCCTGGA CCGCCTCCAA CTGGAATACG TTGACATAGT ATTTGCCAAT 
CGTTCAGACC CCAGCAGTCC TATGGAGGAG ATTGTAAGAG CCATGACCTA TGTCATCAAC 
CAGGGCCTGG CCCTATACTG GGGGACATCC AGGTGGAGTG CTGCAGAAAT CATGGAGGCC 
TACTCCATGG CCAGACAGTT CAATCTGATC CCTCCTGTGT GTGAACAAGC GGAGAACCAC 
TTCTTTCAGA GGGAGAAGGT GGAGATGCAG CTGCCTGAGC TCTACCACAA AATTGGTGTT 
GGCTCAGTCA CTTGGTCTCC CCTGGCGTGC AGCCTCATTA CTAGCAAGTA CGATGGGCAA 
GTTCCAGATG CTTGCAAGGC CACTGTCAAG GGCTACCAGT GGCTCAAAGA AAAAGTGCAA 
AGTGAAGATG GCAAGAAGCA ACAAGCCAGA GTGACGGACC TTCTCCCCAT CGCTCACCAG 
CTAGGCTGCA CCGTGGCCCA ACTTGCTATA GCCTGGTGTC TCCGAAGCGA AGGTGTCAGC 
TCAGTTTTAC TGGGGGTGTC CAGTGCAGAG CAGCTGATGG AACATCTGGG CTCCCTACAG 
GTGCTGGGTC AGCTGACGCC GCAAACGGTG ATGGAAATAG ATGCGCTCTT GGGGAACAAA 
TCGCATTCCA AGAAATAG