Emx2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Emx2
Entrez Gene ID	499380
Full Name	empty spiracles homeobox 2
Synonyms	RGD1564797
General protein information	Preferred Names empty spiracles homeobox 2 Names homeobox protein EMX2 empty spiracles homolog 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q55

mRNA and Protein(s)

mRNA	Protein	Name
XM_017589593.1	XP_017445082.1	homeobox protein EMX2 isoform X1
NM_001109169.1	NP_001102639.1	homeobox protein EMX2

Pathways from BioSystems

Homologies

	EMX2	XP_001095904.1
Gallus gallus (chicken)	EMX2	XP_421783.2
Pan troglodytes (chimpanzee)	EMX2	XP_001152098.1
Bos taurus (cattle)	EMX2	NP_001069313.1
Xenopus tropicalis (tropical clawed frog)	emx2	NP_001128284.1
Homo sapiens (human)	EMX2	NP_004089.1
Mus musculus (house mouse)	Emx2	NP_034262.2
Rattus norvegicus (Norway rat)	Emx2	NP_001102639.1
Canis lupus familiaris (dog)	EMX2	XP_853333.1
Danio rerio (zebrafish)	emx2	NP_571355.2

Gene Ontology
Bibliography

Related articles in PubMed

Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for Pax2 and Emx2.
Boualia SK, Gaitan Y, Murawski I, Nadon R, Gupta IR, Bouchard M
PloS one6(6)e21529(2011)

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.
Li H, Bishop KM, O'Leary DD
Molecular and cellular neurosciences33(2)136-49(2006 Oct)

Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium.
Kimura J, Suda Y, Kurokawa D, Hossain ZM, Nakamura M, Takahashi M, Hara A, Aizawa S
The Journal of neuroscience : the official journal of the Society for Neuroscience25(21)5097-108(2005 May)

EMX2 regulates sizes and positioning of the primary sensory and motor areas in neocortex by direct specification of cortical progenitors.
Hamasaki T, Leing?rtner A, Ringstedt T, O'Leary DD
Neuron43(3)359-72(2004 Aug)

Emx1 and Emx2 cooperate in initial phase of archipallium development.
Shinozaki K, Yoshida M, Nakamura M, Aizawa S, Suda Y
Mechanisms of development121(5)475-89(2004 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Emx2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Emx2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09208	NM_001109169.1 Latest version!	Rattus norvegicus empty spiracles homeobox 2 (Emx2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
ORa49205	XM_017589593.1 Latest version!	Rattus norvegicus empty spiracles homeobox 2 (Emx2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Emx2 ( NM_001109169.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102639.1 Rattus norvegicus empty spiracles homeobox 2 (Emx2), mRNA.

Price & Availability↑

CloneID	ORa09208
Clone ID Related Accession (Same CDS sequence)	NM_001109169.1
Accession Version	NM_001109169.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein EMX2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473986.1. On or before Oct 4, 2007 this sequence version replaced XM_001065767.1, XM_574698.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689595, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END##

ATGTTTCAGC CGGCGCCTAA GCGCTGCTTC ACCATCGAGT CGCTGGTGGC CAAGGACAGT 
CCCCTGCCTG CCTCACGCTC CGAGGATCCC ATCCGTCCCG CGGCGCTCAG CTACGCCAAT 
TCCAGCCCCA TAAATCCGTT CCTCAACGGC TTCCACTCGG CCGCCGCCGC CGCCGCCGCG 
GGCAGGGGCG TCTACTCCAA CCCGGACTTG GTGTTCGCCG AGGCGGTCTC GCACCCGCCC 
AACCCCGCCG TGCCGGTGCA CCCGGTGCCG CCGCCGCACG CCCTGGCCGC CCACCCCCTG 
CCCTCCTCGC ATTCGCCACA CCCCCTCTTC GCCTCGCAGC AGCGGGACCC GTCCACCTTC 
TACCCCTGGC TCATCCACCG CTACCGATAT CTGGGTCATC GCTTCCAAGG GAACGACACA 
AGTCCCGAGA GTTTCCTTTT GCACAACGCT CTGGCTCGAA AGCCGAAGCG GATTCGAACC 
GCCTTCTCTC CGTCCCAGCT TTTAAGGCTA GAACACGCGT TCGAGAAGAA TCATTACGTG 
GTGGGAGCGG AAAGGAAGCA GCTGGCGCAC AGTCTCAGCC TTACGGAAAC TCAGGTAAAA 
GTATGGTTTC AGAACCGGAG AACGAAATTC AAAAGGCAAA AGCTAGAGGA AGAAGGCTCA 
GATTCCCAAC AAAAGAAAAA AGGGACACAC CACATTAACC GGTGGAGAAT TGCTACCAAG 
CAGGCGAGTC CGGAGGAAAT AGACGTGACC TCAGACGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102639.1
CDS	847..1608
Translation	MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD

Target ORF information:

RefSeq Version	NM_001109169.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus empty spiracles homeobox 2 (Emx2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109169.1

ORF Insert Sequence:

ATGTTTCAGC CGGCGCCTAA GCGCTGCTTC ACCATCGAGT CGCTGGTGGC CAAGGACAGT 
CCCCTGCCTG CCTCACGCTC CGAGGATCCC ATCCGTCCCG CGGCGCTCAG CTACGCCAAT 
TCCAGCCCCA TAAATCCGTT CCTCAACGGC TTCCACTCGG CCGCCGCCGC CGCCGCCGCG 
GGCAGGGGCG TCTACTCCAA CCCGGACTTG GTGTTCGCCG AGGCGGTCTC GCACCCGCCC 
AACCCCGCCG TGCCGGTGCA CCCGGTGCCG CCGCCGCACG CCCTGGCCGC CCACCCCCTG 
CCCTCCTCGC ATTCGCCACA CCCCCTCTTC GCCTCGCAGC AGCGGGACCC GTCCACCTTC 
TACCCCTGGC TCATCCACCG CTACCGATAT CTGGGTCATC GCTTCCAAGG GAACGACACA 
AGTCCCGAGA GTTTCCTTTT GCACAACGCT CTGGCTCGAA AGCCGAAGCG GATTCGAACC 
GCCTTCTCTC CGTCCCAGCT TTTAAGGCTA GAACACGCGT TCGAGAAGAA TCATTACGTG 
GTGGGAGCGG AAAGGAAGCA GCTGGCGCAC AGTCTCAGCC TTACGGAAAC TCAGGTAAAA 
GTATGGTTTC AGAACCGGAG AACGAAATTC AAAAGGCAAA AGCTAGAGGA AGAAGGCTCA 
GATTCCCAAC AAAAGAAAAA AGGGACACAC CACATTAACC GGTGGAGAAT TGCTACCAAG 
CAGGCGAGTC CGGAGGAAAT AGACGTGACC TCAGACGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Emx2 ( XM_017589593.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017445082.1 Rattus norvegicus empty spiracles homeobox 2 (Emx2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa49205
Clone ID Related Accession (Same CDS sequence)	XM_017589593.1
Accession Version	XM_017589593.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 513bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein EMX2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END##

ATGTTTCAGC CGGCGCCTAA GCGCTGCTTC ACCATCGAGT CGCTGGTGGC CAAGGACAGT 
CCCCTGCCTG CCTCACGCTC CGAGGATCCC ATCCGTCCCG CGGCGCTCAG CTACGCCAAT 
TCCAGCCCCA TAAATCCGTT CCTCAACGGC TTCCACTCGG CCGCCGCCGC CGCCGCCGCG 
GGCAGGGGCG TCTACTCCAA CCCGGACTTG GTGTTCGCCG AGGCGGTCTC GCACCCGCCC 
AACCCCGCCG TGCCGGTGCA CCCGGTGCCG CCGCCGCACG CCCTGGCCGC CCACCCCCTG 
CCCTCCTCGC ATTCGCCACA CCCCCTCTTC GCCTCGCAGC AGCGGGACCC GTCCACCTTC 
TACCCCTGGC TCATCCACCG CTACCGATAT CTGGGTCATC GCTTCCAAGG TAAAAGTATG 
GTTTCAGAAC CGGAGAACGA AATTCAAAAG GCAAAAGCTA GAGGAAGAAG GCTCAGATTC 
CCAACAAAAG AAAAAAGGGA CACACCACAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017445082.1
CDS	28..540
Translation	MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGKSMVSEPENEIQKAKARGRRLRFPTKEKRDTPH

Target ORF information:

RefSeq Version	XM_017589593.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus empty spiracles homeobox 2 (Emx2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589593.1

ORF Insert Sequence:

ATGTTTCAGC CGGCGCCTAA GCGCTGCTTC ACCATCGAGT CGCTGGTGGC CAAGGACAGT 
CCCCTGCCTG CCTCACGCTC CGAGGATCCC ATCCGTCCCG CGGCGCTCAG CTACGCCAAT 
TCCAGCCCCA TAAATCCGTT CCTCAACGGC TTCCACTCGG CCGCCGCCGC CGCCGCCGCG 
GGCAGGGGCG TCTACTCCAA CCCGGACTTG GTGTTCGCCG AGGCGGTCTC GCACCCGCCC 
AACCCCGCCG TGCCGGTGCA CCCGGTGCCG CCGCCGCACG CCCTGGCCGC CCACCCCCTG 
CCCTCCTCGC ATTCGCCACA CCCCCTCTTC GCCTCGCAGC AGCGGGACCC GTCCACCTTC 
TACCCCTGGC TCATCCACCG CTACCGATAT CTGGGTCATC GCTTCCAAGG TAAAAGTATG 
GTTTCAGAAC CGGAGAACGA AATTCAAAAG GCAAAAGCTA GAGGAAGAAG GCTCAGATTC 
CCAACAAAAG AAAAAAGGGA CACACCACAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for Pax2 and Emx2.
PloS one6(6)e21529(2011)
Boualia SK,Gaitan Y,Murawski I,Nadon R,Gupta IR,Bouchard M

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.
Molecular and cellular neurosciences33(2)136-49(2006 Oct)
Li H,Bishop KM,O'Leary DD

Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium.
The Journal of neuroscience : the official journal of the Society for Neuroscience25(21)5097-108(2005 May)
Kimura J,Suda Y,Kurokawa D,Hossain ZM,Nakamura M,Takahashi M,Hara A,Aizawa S

EMX2 regulates sizes and positioning of the primary sensory and motor areas in neocortex by direct specification of cortical progenitors.
Neuron43(3)359-72(2004 Aug)
Hamasaki T,Leing?rtner A,Ringstedt T,O'Leary DD

Emx1 and Emx2 cooperate in initial phase of archipallium development.
Mechanisms of development121(5)475-89(2004 May)
Shinozaki K,Yoshida M,Nakamura M,Aizawa S,Suda Y