Lax1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lax1
Entrez Gene ID	498232
Full Name	lymphocyte transmembrane adaptor 1
General protein information	Preferred Names lymphocyte transmembrane adaptor 1 Names lymphocyte transmembrane adapter 1 membrane-associated adapter protein LAX
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017491.1	NP_001017491.1	lymphocyte transmembrane adapter 1
XM_017598879.1	XP_017454368.1	lymphocyte transmembrane adapter 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LAX1	XP_001156566.1
Mus musculus (house mouse)	Lax1	NP_001153121.1
Homo sapiens (human)	LAX1	NP_060243.2
Bos taurus (cattle)	LAX1	NP_001015674.1
Rattus norvegicus (Norway rat)	Lax1	NP_001017491.1
	LAX1	XP_001101278.1
Canis lupus familiaris (dog)	LAX1	XP_003434375.2

Gene Ontology
Bibliography

Related articles in PubMed

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Negative regulation of lymphocyte activation by the adaptor protein LAX.
Zhu M, Granillo O, Wen R, Yang K, Dai X, Wang D, Zhang W
Journal of immunology (Baltimore, Md. : 1950)174(9)5612-9(2005 May)

Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.
Zhu M, Janssen E, Leung K, Zhang W
The Journal of biological chemistry277(48)46151-8(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lax1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lax1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05978	NM_001017491.1 Latest version!	Rattus norvegicus lymphocyte transmembrane adaptor 1 (Lax1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa05978	XM_017598879.1 Latest version!	Rattus norvegicus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lax1 ( NM_001017491.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001017491.1 Rattus norvegicus lymphocyte transmembrane adaptor 1 (Lax1), mRNA.

Price & Availability↑

CloneID	ORa05978
Clone ID Related Accession (Same CDS sequence)	NM_001017491.1 , XM_017598879.1
Accession Version	NM_001017491.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Rattus norvegicus(Norway rat)
Product	lymphocyte transmembrane adapter 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC089837.1. On Apr 29, 2005 this sequence version replaced XM_573453.1. ##Evidence-Data-START## Transcript exon combination :: BC089837.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGTACACCA CCCCAGCCCC TCCAGAGATC ACAAGAAGGA GCTCAGAGCC AAGCACTCAG 
CAGGGGACTC TTGGCAGCCT GGAAGGAGAG AAAGGCCACC TCCTCTTCCC TGGTTTTGTG 
GTGCTCGTGA CCATCTTCCT GGTTGTCATA GTTACCTGTA TCCTGTGGAG CCGGAAGAAA 
CAGAAGAAGC GGCGTGTTCC TTACCTCCAA GTAACTCCGT CACTGGCTCT GCCTCCACCC 
AGGCAGCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTTAG TACCGAGAGC CTCCTCTCCA GAGCGTCCGA CAGCCCTGAG 
CCTGAGGTCC CCCAAGCCAG TGGTTCCCTT CAGAAGCATA GAGCATCTGT TCATGCCGTG 
GAGTACACAG TAGGCGTCTA TGACAATGGT ACAGTGGCCC AGATGTGCGG GCCCTTGGCC 
TCCTCAGCAC ATCGCGTATG TGACGGAACT TCCAGAAATA ACAGCATTTC TTCCAAGGAG 
TCAAATGATT ATGTCAATAT CCCCACAGCG GAGGACACCA GTGAGACTCT GACTTGTACC 
AAAAGCACTC CTGAAAGTCA CCTTGGTCTT CCAAGTGGCC AGCGGCTGGA ATTTGCTGAA 
GGAGGGCATG CAGGCTGTGG GAAGGCCACC GATCGCACCG GCGTGTGGGC TCCAGGACTC 
CAGGGTAGTA ATTCACTCAG CGAAGGAGAC GATTCATCTC AGAGTTCAAA CGACTATGTC 
AATATGACAG GGTTGGATCT TGAGGACATC CAAGAGAGTC GACCCAGGGT CGCTTTTCAG 
TGCTGCAGAG ATTATGAAAA TGTCCCGCCA GTAGTTGCCA ATGGAAGCCA GCTGCAGACT 
GTGGAAGAAG TGACATCTTC AACCACAGAC CGTGGAGAGC CTGCCCAGAG GACGCTACCT 
TCAGTGTATC ACATGGCATT TCGGCCGTCT GCATGGAGTG AGGACGGTGC CATGATACCT 
GGAGAAGAGG CGTCAAATGG GGACTCTAGT GACTATGAGA ATGTGCTGGT CCCCGAGTTA 
GAAGGCAAGG ACTGGAAACA GGGACCCGGT ACTTGGCATC CTTCTGATGA AAGAACACCA 
AGTGACCAAG CTGGAAAGTT TTGTGAGGCA GTCTACCCTG CTGGGTCTTT AGCCACTGAA 
ACATCTGGTG AAGAGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017491.1
CDS	350..1570
Translation	MYTTPAPPEITRRSSEPSTQQGTLGSLEGEKGHLLFPGFVVLVTIFLVVIVTCILWSRKKQKKRRVPYLQVTPSLALPPPRQRAKNIYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEVPQASGSLQKHRASVHAVEYTVGVYDNGTVAQMCGPLASSAHRVCDGTSRNNSISSKESNDYVNIPTAEDTSETLTCTKSTPESHLGLPSGQRLEFAEGGHAGCGKATDRTGVWAPGLQGSNSLSEGDDSSQSSNDYVNMTGLDLEDIQESRPRVAFQCCRDYENVPPVVANGSQLQTVEEVTSSTTDRGEPAQRTLPSVYHMAFRPSAWSEDGAMIPGEEASNGDSSDYENVLVPELEGKDWKQGPGTWHPSDERTPSDQAGKFCEAVYPAGSLATETSGEEV

Target ORF information:

RefSeq Version	NM_001017491.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphocyte transmembrane adaptor 1 (Lax1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017491.1

ORF Insert Sequence:

ATGTACACCA CCCCAGCCCC TCCAGAGATC ACAAGAAGGA GCTCAGAGCC AAGCACTCAG 
CAGGGGACTC TTGGCAGCCT GGAAGGAGAG AAAGGCCACC TCCTCTTCCC TGGTTTTGTG 
GTGCTCGTGA CCATCTTCCT GGTTGTCATA GTTACCTGTA TCCTGTGGAG CCGGAAGAAA 
CAGAAGAAGC GGCGTGTTCC TTACCTCCAA GTAACTCCGT CACTGGCTCT GCCTCCACCC 
AGGCAGCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTTAG TACCGAGAGC CTCCTCTCCA GAGCGTCCGA CAGCCCTGAG 
CCTGAGGTCC CCCAAGCCAG TGGTTCCCTT CAGAAGCATA GAGCATCTGT TCATGCCGTG 
GAGTACACAG TAGGCGTCTA TGACAATGGT ACAGTGGCCC AGATGTGCGG GCCCTTGGCC 
TCCTCAGCAC ATCGCGTATG TGACGGAACT TCCAGAAATA ACAGCATTTC TTCCAAGGAG 
TCAAATGATT ATGTCAATAT CCCCACAGCG GAGGACACCA GTGAGACTCT GACTTGTACC 
AAAAGCACTC CTGAAAGTCA CCTTGGTCTT CCAAGTGGCC AGCGGCTGGA ATTTGCTGAA 
GGAGGGCATG CAGGCTGTGG GAAGGCCACC GATCGCACCG GCGTGTGGGC TCCAGGACTC 
CAGGGTAGTA ATTCACTCAG CGAAGGAGAC GATTCATCTC AGAGTTCAAA CGACTATGTC 
AATATGACAG GGTTGGATCT TGAGGACATC CAAGAGAGTC GACCCAGGGT CGCTTTTCAG 
TGCTGCAGAG ATTATGAAAA TGTCCCGCCA GTAGTTGCCA ATGGAAGCCA GCTGCAGACT 
GTGGAAGAAG TGACATCTTC AACCACAGAC CGTGGAGAGC CTGCCCAGAG GACGCTACCT 
TCAGTGTATC ACATGGCATT TCGGCCGTCT GCATGGAGTG AGGACGGTGC CATGATACCT 
GGAGAAGAGG CGTCAAATGG GGACTCTAGT GACTATGAGA ATGTGCTGGT CCCCGAGTTA 
GAAGGCAAGG ACTGGAAACA GGGACCCGGT ACTTGGCATC CTTCTGATGA AAGAACACCA 
AGTGACCAAG CTGGAAAGTT TTGTGAGGCA GTCTACCCTG CTGGGTCTTT AGCCACTGAA 
ACATCTGGTG AAGAGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lax1 ( XM_017598879.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454368.1 Rattus norvegicus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa05978
Clone ID Related Accession (Same CDS sequence)	NM_001017491.1 , XM_017598879.1
Accession Version	XM_017598879.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphocyte transmembrane adapter 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACACCA CCCCAGCCCC TCCAGAGATC ACAAGAAGGA GCTCAGAGCC AAGCACTCAG 
CAGGGGACTC TTGGCAGCCT GGAAGGAGAG AAAGGCCACC TCCTCTTCCC TGGTTTTGTG 
GTGCTCGTGA CCATCTTCCT GGTTGTCATA GTTACCTGTA TCCTGTGGAG CCGGAAGAAA 
CAGAAGAAGC GGCGTGTTCC TTACCTCCAA GTAACTCCGT CACTGGCTCT GCCTCCACCC 
AGGCAGCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTTAG TACCGAGAGC CTCCTCTCCA GAGCGTCCGA CAGCCCTGAG 
CCTGAGGTCC CCCAAGCCAG TGGTTCCCTT CAGAAGCATA GAGCATCTGT TCATGCCGTG 
GAGTACACAG TAGGCGTCTA TGACAATGGT ACAGTGGCCC AGATGTGCGG GCCCTTGGCC 
TCCTCAGCAC ATCGCGTATG TGACGGAACT TCCAGAAATA ACAGCATTTC TTCCAAGGAG 
TCAAATGATT ATGTCAATAT CCCCACAGCG GAGGACACCA GTGAGACTCT GACTTGTACC 
AAAAGCACTC CTGAAAGTCA CCTTGGTCTT CCAAGTGGCC AGCGGCTGGA ATTTGCTGAA 
GGAGGGCATG CAGGCTGTGG GAAGGCCACC GATCGCACCG GCGTGTGGGC TCCAGGACTC 
CAGGGTAGTA ATTCACTCAG CGAAGGAGAC GATTCATCTC AGAGTTCAAA CGACTATGTC 
AATATGACAG GGTTGGATCT TGAGGACATC CAAGAGAGTC GACCCAGGGT CGCTTTTCAG 
TGCTGCAGAG ATTATGAAAA TGTCCCGCCA GTAGTTGCCA ATGGAAGCCA GCTGCAGACT 
GTGGAAGAAG TGACATCTTC AACCACAGAC CGTGGAGAGC CTGCCCAGAG GACGCTACCT 
TCAGTGTATC ACATGGCATT TCGGCCGTCT GCATGGAGTG AGGACGGTGC CATGATACCT 
GGAGAAGAGG CGTCAAATGG GGACTCTAGT GACTATGAGA ATGTGCTGGT CCCCGAGTTA 
GAAGGCAAGG ACTGGAAACA GGGACCCGGT ACTTGGCATC CTTCTGATGA AAGAACACCA 
AGTGACCAAG CTGGAAAGTT TTGTGAGGCA GTCTACCCTG CTGGGTCTTT AGCCACTGAA 
ACATCTGGTG AAGAGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454368.1
CDS	407..1627
Translation	MYTTPAPPEITRRSSEPSTQQGTLGSLEGEKGHLLFPGFVVLVTIFLVVIVTCILWSRKKQKKRRVPYLQVTPSLALPPPRQRAKNIYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEVPQASGSLQKHRASVHAVEYTVGVYDNGTVAQMCGPLASSAHRVCDGTSRNNSISSKESNDYVNIPTAEDTSETLTCTKSTPESHLGLPSGQRLEFAEGGHAGCGKATDRTGVWAPGLQGSNSLSEGDDSSQSSNDYVNMTGLDLEDIQESRPRVAFQCCRDYENVPPVVANGSQLQTVEEVTSSTTDRGEPAQRTLPSVYHMAFRPSAWSEDGAMIPGEEASNGDSSDYENVLVPELEGKDWKQGPGTWHPSDERTPSDQAGKFCEAVYPAGSLATETSGEEV

Target ORF information:

RefSeq Version	XM_017598879.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017598879.1

ORF Insert Sequence:

ATGTACACCA CCCCAGCCCC TCCAGAGATC ACAAGAAGGA GCTCAGAGCC AAGCACTCAG 
CAGGGGACTC TTGGCAGCCT GGAAGGAGAG AAAGGCCACC TCCTCTTCCC TGGTTTTGTG 
GTGCTCGTGA CCATCTTCCT GGTTGTCATA GTTACCTGTA TCCTGTGGAG CCGGAAGAAA 
CAGAAGAAGC GGCGTGTTCC TTACCTCCAA GTAACTCCGT CACTGGCTCT GCCTCCACCC 
AGGCAGCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTTAG TACCGAGAGC CTCCTCTCCA GAGCGTCCGA CAGCCCTGAG 
CCTGAGGTCC CCCAAGCCAG TGGTTCCCTT CAGAAGCATA GAGCATCTGT TCATGCCGTG 
GAGTACACAG TAGGCGTCTA TGACAATGGT ACAGTGGCCC AGATGTGCGG GCCCTTGGCC 
TCCTCAGCAC ATCGCGTATG TGACGGAACT TCCAGAAATA ACAGCATTTC TTCCAAGGAG 
TCAAATGATT ATGTCAATAT CCCCACAGCG GAGGACACCA GTGAGACTCT GACTTGTACC 
AAAAGCACTC CTGAAAGTCA CCTTGGTCTT CCAAGTGGCC AGCGGCTGGA ATTTGCTGAA 
GGAGGGCATG CAGGCTGTGG GAAGGCCACC GATCGCACCG GCGTGTGGGC TCCAGGACTC 
CAGGGTAGTA ATTCACTCAG CGAAGGAGAC GATTCATCTC AGAGTTCAAA CGACTATGTC 
AATATGACAG GGTTGGATCT TGAGGACATC CAAGAGAGTC GACCCAGGGT CGCTTTTCAG 
TGCTGCAGAG ATTATGAAAA TGTCCCGCCA GTAGTTGCCA ATGGAAGCCA GCTGCAGACT 
GTGGAAGAAG TGACATCTTC AACCACAGAC CGTGGAGAGC CTGCCCAGAG GACGCTACCT 
TCAGTGTATC ACATGGCATT TCGGCCGTCT GCATGGAGTG AGGACGGTGC CATGATACCT 
GGAGAAGAGG CGTCAAATGG GGACTCTAGT GACTATGAGA ATGTGCTGGT CCCCGAGTTA 
GAAGGCAAGG ACTGGAAACA GGGACCCGGT ACTTGGCATC CTTCTGATGA AAGAACACCA 
AGTGACCAAG CTGGAAAGTT TTGTGAGGCA GTCTACCCTG CTGGGTCTTT AGCCACTGAA 
ACATCTGGTG AAGAGGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

Negative regulation of lymphocyte activation by the adaptor protein LAX.
Journal of immunology (Baltimore, Md. : 1950)174(9)5612-9(2005 May)
Zhu M,Granillo O,Wen R,Yang K,Dai X,Wang D,Zhang W

Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.
The Journal of biological chemistry277(48)46151-8(2002 Nov)
Zhu M,Janssen E,Leung K,Zhang W