Spink6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Spink6
Entrez Gene ID	408235
Full Name	serine peptidase inhibitor, Kazal type 6
Synonyms	Spink5l1
General protein information	Preferred Names serine peptidase inhibitor, Kazal type 6 Names serine protease inhibitor Kazal-type 6 Kazal type serine protease inhibitor 1 serine protease inhibitor Kazal-type 6-like
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq21
Summary	predicted to act as a serine protease inhibitor [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001008874.1	NP_001008874.1	serine protease inhibitor Kazal-type 6 precursor
XM_003752044.1	XP_003752092.1	serine protease inhibitor Kazal-type 6 isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Characterization of Spink6 in mouse skin: the conserved inhibitor of kallikrein-related peptidases is reduced by barrier injury.
Fischer J, Wu Z, Kantyka T, Sperrhacke M, Dimitrieva O, Koblyakova Y, Ahrens K, Graumann N, Baurecht H, Reiss K, Schr?der JM, Proksch E, Meyer-Hoffert U
The Journal of investigative dermatology134(5)1305-1312(2014 May)

A genomic analysis of rat proteases and protease inhibitors.
Puente XS, L?pez-Ot?n C
Genome research14(4)609-22(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Spink6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Spink6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa39738	NM_001008874.1 Latest version!	Rattus norvegicus serine peptidase inhibitor, Kazal type 6 (Spink6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa21885	XM_003752044.1 Latest version!	Rattus norvegicus serine peptidase inhibitor, Kazal type 6 (Spink6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Spink6 ( NM_001008874.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001008874.1 Rattus norvegicus serine peptidase inhibitor, Kazal type 6 (Spink6), mRNA.

Price & Availability↑

CloneID	ORa39738
Clone ID Related Accession (Same CDS sequence)	NM_001008874.1
Accession Version	NM_001008874.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	serine protease inhibitor Kazal-type 6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BN000346.1. On Apr 19, 2005 this sequence version replaced XM_579266.1. ##Evidence-Data-START## Transcript exon combination :: BN000346.1 [ECO:0000332] ##Evidence-Data-END##

ATGAAAGTAG CAGGTGTCTT TCTGCTCCTC TCTCTGGCTC TTCTCTGCTT TTTCTCAGGT 
GAGTTTAGTC AAGGAGGACA GGACAAAAGA GGCTGGATCA CAAGATCAGA GGGCCGATTT 
CCAGGGAAAG GTGTCTTAAG GCATCGTCTC TTTCAAATTA ATTGTGGTGA GTTCCGTGAT 
CCCAAGGTCT TCTGCACTCG GGAATCTGAC CCACTCTGTG GCTCTGATGG CCAGACATAT 
GGGAATAAAT GTGCCTTCTG CAAGGCATTG GAGAAAAGTT CTGGAAAGAT CAACCTGAAG 
CATCGTGGGA AATGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008874.1
CDS	1..318
Translation	MKVAGVFLLLSLALLCFFSGEFSQGGQDKRGWITRSEGRFPGKGVLRHRLFQINCGEFRDPKVFCTRESDPLCGSDGQTYGNKCAFCKALEKSSGKINLKHRGKC

Target ORF information:

RefSeq Version	NM_001008874.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus serine peptidase inhibitor, Kazal type 6 (Spink6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008874.1

ORF Insert Sequence:

ATGAAAGTAG CAGGTGTCTT TCTGCTCCTC TCTCTGGCTC TTCTCTGCTT TTTCTCAGGT 
GAGTTTAGTC AAGGAGGACA GGACAAAAGA GGCTGGATCA CAAGATCAGA GGGCCGATTT 
CCAGGGAAAG GTGTCTTAAG GCATCGTCTC TTTCAAATTA ATTGTGGTGA GTTCCGTGAT 
CCCAAGGTCT TCTGCACTCG GGAATCTGAC CCACTCTGTG GCTCTGATGG CCAGACATAT 
GGGAATAAAT GTGCCTTCTG CAAGGCATTG GAGAAAAGTT CTGGAAAGAT CAACCTGAAG 
CATCGTGGGA AATGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Spink6 ( XM_003752044.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_003752092.1 Rattus norvegicus serine peptidase inhibitor, Kazal type 6 (Spink6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa21885
Clone ID Related Accession (Same CDS sequence)	XM_003752044.1
Accession Version	XM_003752044.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine protease inhibitor Kazal-type 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGTAG CAGGTGTCTT TCTGCTCCTC TCTCTGGCTC TTCTCTGCTT TTTCTCAGGT 
GCCTTCAGTC AAGGAGGACA GGACAAAAGA GGCTGGATCA CAAGATCAGA GGGCCGATTT 
CCAGGGAAAG GTGTCTTAAG GCATCGTCTC TTTCAAATTA ATTGTGGTGA GTTCCGTGAT 
CCCAAGGTCT TCTGCACTCG GGAATCTGAC CCACTCTGTG GCTCTGATGG CCAGACATAT 
GGGAATAAAT GTGCCTTCTG CAAGGCATTG GAGAAAAGTT CTGGAAAGAT CAACCTGAAG 
CATCGTGGGA AATGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_003752092.1
CDS	1..318
Translation	MKVAGVFLLLSLALLCFFSGAFSQGGQDKRGWITRSEGRFPGKGVLRHRLFQINCGEFRDPKVFCTRESDPLCGSDGQTYGNKCAFCKALEKSSGKINLKHRGKC

Target ORF information:

RefSeq Version	XM_003752044.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus serine peptidase inhibitor, Kazal type 6 (Spink6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_003752044.1

ORF Insert Sequence:

ATGAAAGTAG CAGGTGTCTT TCTGCTCCTC TCTCTGGCTC TTCTCTGCTT TTTCTCAGGT 
GCCTTCAGTC AAGGAGGACA GGACAAAAGA GGCTGGATCA CAAGATCAGA GGGCCGATTT 
CCAGGGAAAG GTGTCTTAAG GCATCGTCTC TTTCAAATTA ATTGTGGTGA GTTCCGTGAT 
CCCAAGGTCT TCTGCACTCG GGAATCTGAC CCACTCTGTG GCTCTGATGG CCAGACATAT 
GGGAATAAAT GTGCCTTCTG CAAGGCATTG GAGAAAAGTT CTGGAAAGAT CAACCTGAAG 
CATCGTGGGA AATGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterization of Spink6 in mouse skin: the conserved inhibitor of kallikrein-related peptidases is reduced by barrier injury.
The Journal of investigative dermatology134(5)1305-1312(2014 May)
Fischer J,Wu Z,Kantyka T,Sperrhacke M,Dimitrieva O,Koblyakova Y,Ahrens K,Graumann N,Baurecht H,Reiss K,Schr?der JM,Proksch E,Meyer-Hoffert U

A genomic analysis of rat proteases and protease inhibitors.
Genome research14(4)609-22(2004 Apr)
Puente XS,L?pez-Ot?n C