Prss58 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prss58
Entrez Gene ID	408204
Full Name	protease, serine, 58
Synonyms	Tryx3,try1
General protein information	Preferred Names protease, serine, 58 Names putative inactive serine protease 58 putative trypsin-X3 trypsin-X3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q23
Summary	member of the trypsin family of serine proteases [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009174.1	NP_001009174.1	putative inactive serine protease 58 precursor
XM_017592738.1	XP_017448227.1	putative inactive serine protease 58 isoform X1
XM_017592739.1	XP_017448228.1	putative inactive serine protease 58 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PRSS58	NP_001035599.1
Mus musculus (house mouse)	Prss58	NP_778185.1
Rattus norvegicus (Norway rat)	Prss58	NP_001009174.1
Homo sapiens (human)	PRSS58	NP_001001317.1
Canis lupus familiaris (dog)	LOC475522	XP_532745.2
Pan troglodytes (chimpanzee)	LOC742071	XP_001157102.1
	PRSS58	XP_001085477.1

Gene Ontology
Bibliography

Related articles in PubMed

Long-term nicotine exposure causes increased concentrations of trypsinogens and amylase in pancreatic extracts in the rat.
Lindkvist B, Wierup N, Sundler F, Borgstr?m A
Pancreas37(3)288-94(2008 Oct)

A genomic analysis of rat proteases and protease inhibitors.
Puente XS, L?pez-Ot?n C
Genome research14(4)609-22(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Nicotine impairs secretion rather than production of pancreatic trypsinogen 1.
Title: Long-term nicotine exposure causes increased concentrations of trypsinogens and amylase in pancreatic extracts in the rat.

The following Prss58 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prss58 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09495	NM_001009174.1 Latest version!	Rattus norvegicus serine protease 58 (Prss58), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa09495	XM_017592738.1 Latest version!	Rattus norvegicus protease, serine, 58 (Prss58), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa09495	XM_017592739.1 Latest version!	Rattus norvegicus protease, serine, 58 (Prss58), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prss58 ( NM_001009174.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001009174.1 Rattus norvegicus serine protease 58 (Prss58), mRNA.

Price & Availability↑

CloneID	ORa09495
Clone ID Related Accession (Same CDS sequence)	NM_001009174.1 , XM_017592738.1 , XM_017592739.1
Accession Version	NM_001009174.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	putative inactive serine protease 58 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BN000387.1. On Apr 19, 2005 this sequence version replaced XM_579279.1. ##Evidence-Data-START## Transcript exon combination :: BN000387.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689604, SAMN02642708 [ECO:0000348] ##Evidence-Data-END##

ATGAAGTTAG TCTTCTGCAT TCTTTCAACC CTGCTTGGTA CCTTTGCCTA TAATCCAGAT 
CACATAGCTG GCACCACTCC CCCCTACTTA GTCTACCTGA AGTCTGATTA CTTGCCCTGT 
ACTGGAGTCC TGATCCATCC TCTTTGGGTG GTCACATCTG CACACTGCAA TTTACCGGAC 
CTCCGGGTGA TTCTTGGGAT AACAAACCCA GCAGATACCA CAGAACATGA CGTGGAGGTG 
TCTGACTATG AGAAAATGTT CCGTCATCCA TACTTCTCGG TCTCTTCTAT TTCATATGAC 
CTTATGTTAA TCAAACTGAG AAGAGGGATT AAGCACAGTT ACTATGCAAA AGCAGTCAAG 
CTACCTCAAC ACACTGTGCC TGTGAATGCC ATGTGCTCTG TGTCTACCTG GGCCTACAAT 
CTATGTGACG TCACCAAGGA ACCTGACTCA CTGCAGACTG TGAACGTCTC TGTAATCTCC 
AAGGCTGAGT GTCATAATGC CTATAAAGCC TTTGACATCC GAGAAAACAT GATCTGTGTG 
GGCATCGTGC CAGGACGGAG GCTGCCCTGC AAGGAAGTCA CGGCTGCCCC AGCGGTCTGC 
AATGGGGTAC TTTATGGAAT ATTATCTTAT GCAGATGGCT GCGTTTTGAG AGCTGATGTT 
GGCATCTATG CTAGCATCTT TCACTACATG CCCTGGATTG AAAATATCAT GAAAAATAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009174.1
CDS	1..723
Translation	MKLVFCILSTLLGTFAYNPDHIAGTTPPYLVYLKSDYLPCTGVLIHPLWVVTSAHCNLPDLRVILGITNPADTTEHDVEVSDYEKMFRHPYFSVSSISYDLMLIKLRRGIKHSYYAKAVKLPQHTVPVNAMCSVSTWAYNLCDVTKEPDSLQTVNVSVISKAECHNAYKAFDIRENMICVGIVPGRRLPCKEVTAAPAVCNGVLYGILSYADGCVLRADVGIYASIFHYMPWIENIMKNN

Target ORF information:

RefSeq Version	NM_001009174.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus serine protease 58 (Prss58), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009174.1

ORF Insert Sequence:

ATGAAGTTAG TCTTCTGCAT TCTTTCAACC CTGCTTGGTA CCTTTGCCTA TAATCCAGAT 
CACATAGCTG GCACCACTCC CCCCTACTTA GTCTACCTGA AGTCTGATTA CTTGCCCTGT 
ACTGGAGTCC TGATCCATCC TCTTTGGGTG GTCACATCTG CACACTGCAA TTTACCGGAC 
CTCCGGGTGA TTCTTGGGAT AACAAACCCA GCAGATACCA CAGAACATGA CGTGGAGGTG 
TCTGACTATG AGAAAATGTT CCGTCATCCA TACTTCTCGG TCTCTTCTAT TTCATATGAC 
CTTATGTTAA TCAAACTGAG AAGAGGGATT AAGCACAGTT ACTATGCAAA AGCAGTCAAG 
CTACCTCAAC ACACTGTGCC TGTGAATGCC ATGTGCTCTG TGTCTACCTG GGCCTACAAT 
CTATGTGACG TCACCAAGGA ACCTGACTCA CTGCAGACTG TGAACGTCTC TGTAATCTCC 
AAGGCTGAGT GTCATAATGC CTATAAAGCC TTTGACATCC GAGAAAACAT GATCTGTGTG 
GGCATCGTGC CAGGACGGAG GCTGCCCTGC AAGGAAGTCA CGGCTGCCCC AGCGGTCTGC 
AATGGGGTAC TTTATGGAAT ATTATCTTAT GCAGATGGCT GCGTTTTGAG AGCTGATGTT 
GGCATCTATG CTAGCATCTT TCACTACATG CCCTGGATTG AAAATATCAT GAAAAATAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prss58 ( XM_017592738.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448227.1 Rattus norvegicus protease, serine, 58 (Prss58), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa09495
Clone ID Related Accession (Same CDS sequence)	NM_001009174.1 , XM_017592738.1 , XM_017592739.1
Accession Version	XM_017592738.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	putative inactive serine protease 58 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGTTAG TCTTCTGCAT TCTTTCAACC CTGCTTGGTA CCTTTGCCTA TAATCCAGAT 
CACATAGCTG GCACCACTCC CCCCTACTTA GTCTACCTGA AGTCTGATTA CTTGCCCTGT 
ACTGGAGTCC TGATCCATCC TCTTTGGGTG GTCACATCTG CACACTGCAA TTTACCGGAC 
CTCCGGGTGA TTCTTGGGAT AACAAACCCA GCAGATACCA CAGAACATGA CGTGGAGGTG 
TCTGACTATG AGAAAATGTT CCGTCATCCA TACTTCTCGG TCTCTTCTAT TTCATATGAC 
CTTATGTTAA TCAAACTGAG AAGAGGGATT AAGCACAGTT ACTATGCAAA AGCAGTCAAG 
CTACCTCAAC ACACTGTGCC TGTGAATGCC ATGTGCTCTG TGTCTACCTG GGCCTACAAT 
CTATGTGACG TCACCAAGGA ACCTGACTCA CTGCAGACTG TGAACGTCTC TGTAATCTCC 
AAGGCTGAGT GTCATAATGC CTATAAAGCC TTTGACATCC GAGAAAACAT GATCTGTGTG 
GGCATCGTGC CAGGACGGAG GCTGCCCTGC AAGGAAGTCA CGGCTGCCCC AGCGGTCTGC 
AATGGGGTAC TTTATGGAAT ATTATCTTAT GCAGATGGCT GCGTTTTGAG AGCTGATGTT 
GGCATCTATG CTAGCATCTT TCACTACATG CCCTGGATTG AAAATATCAT GAAAAATAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448227.1
CDS	2511..3233
Translation	MKLVFCILSTLLGTFAYNPDHIAGTTPPYLVYLKSDYLPCTGVLIHPLWVVTSAHCNLPDLRVILGITNPADTTEHDVEVSDYEKMFRHPYFSVSSISYDLMLIKLRRGIKHSYYAKAVKLPQHTVPVNAMCSVSTWAYNLCDVTKEPDSLQTVNVSVISKAECHNAYKAFDIRENMICVGIVPGRRLPCKEVTAAPAVCNGVLYGILSYADGCVLRADVGIYASIFHYMPWIENIMKNN

Target ORF information:

RefSeq Version	XM_017592738.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protease, serine, 58 (Prss58), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592738.1

ORF Insert Sequence:

ATGAAGTTAG TCTTCTGCAT TCTTTCAACC CTGCTTGGTA CCTTTGCCTA TAATCCAGAT 
CACATAGCTG GCACCACTCC CCCCTACTTA GTCTACCTGA AGTCTGATTA CTTGCCCTGT 
ACTGGAGTCC TGATCCATCC TCTTTGGGTG GTCACATCTG CACACTGCAA TTTACCGGAC 
CTCCGGGTGA TTCTTGGGAT AACAAACCCA GCAGATACCA CAGAACATGA CGTGGAGGTG 
TCTGACTATG AGAAAATGTT CCGTCATCCA TACTTCTCGG TCTCTTCTAT TTCATATGAC 
CTTATGTTAA TCAAACTGAG AAGAGGGATT AAGCACAGTT ACTATGCAAA AGCAGTCAAG 
CTACCTCAAC ACACTGTGCC TGTGAATGCC ATGTGCTCTG TGTCTACCTG GGCCTACAAT 
CTATGTGACG TCACCAAGGA ACCTGACTCA CTGCAGACTG TGAACGTCTC TGTAATCTCC 
AAGGCTGAGT GTCATAATGC CTATAAAGCC TTTGACATCC GAGAAAACAT GATCTGTGTG 
GGCATCGTGC CAGGACGGAG GCTGCCCTGC AAGGAAGTCA CGGCTGCCCC AGCGGTCTGC 
AATGGGGTAC TTTATGGAAT ATTATCTTAT GCAGATGGCT GCGTTTTGAG AGCTGATGTT 
GGCATCTATG CTAGCATCTT TCACTACATG CCCTGGATTG AAAATATCAT GAAAAATAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prss58 ( XM_017592739.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448228.1 Rattus norvegicus protease, serine, 58 (Prss58), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa09495
Clone ID Related Accession (Same CDS sequence)	NM_001009174.1 , XM_017592738.1 , XM_017592739.1
Accession Version	XM_017592739.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	putative inactive serine protease 58 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGTTAG TCTTCTGCAT TCTTTCAACC CTGCTTGGTA CCTTTGCCTA TAATCCAGAT 
CACATAGCTG GCACCACTCC CCCCTACTTA GTCTACCTGA AGTCTGATTA CTTGCCCTGT 
ACTGGAGTCC TGATCCATCC TCTTTGGGTG GTCACATCTG CACACTGCAA TTTACCGGAC 
CTCCGGGTGA TTCTTGGGAT AACAAACCCA GCAGATACCA CAGAACATGA CGTGGAGGTG 
TCTGACTATG AGAAAATGTT CCGTCATCCA TACTTCTCGG TCTCTTCTAT TTCATATGAC 
CTTATGTTAA TCAAACTGAG AAGAGGGATT AAGCACAGTT ACTATGCAAA AGCAGTCAAG 
CTACCTCAAC ACACTGTGCC TGTGAATGCC ATGTGCTCTG TGTCTACCTG GGCCTACAAT 
CTATGTGACG TCACCAAGGA ACCTGACTCA CTGCAGACTG TGAACGTCTC TGTAATCTCC 
AAGGCTGAGT GTCATAATGC CTATAAAGCC TTTGACATCC GAGAAAACAT GATCTGTGTG 
GGCATCGTGC CAGGACGGAG GCTGCCCTGC AAGGAAGTCA CGGCTGCCCC AGCGGTCTGC 
AATGGGGTAC TTTATGGAAT ATTATCTTAT GCAGATGGCT GCGTTTTGAG AGCTGATGTT 
GGCATCTATG CTAGCATCTT TCACTACATG CCCTGGATTG AAAATATCAT GAAAAATAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448228.1
CDS	2499..3221
Translation	MKLVFCILSTLLGTFAYNPDHIAGTTPPYLVYLKSDYLPCTGVLIHPLWVVTSAHCNLPDLRVILGITNPADTTEHDVEVSDYEKMFRHPYFSVSSISYDLMLIKLRRGIKHSYYAKAVKLPQHTVPVNAMCSVSTWAYNLCDVTKEPDSLQTVNVSVISKAECHNAYKAFDIRENMICVGIVPGRRLPCKEVTAAPAVCNGVLYGILSYADGCVLRADVGIYASIFHYMPWIENIMKNN

Target ORF information:

RefSeq Version	XM_017592739.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protease, serine, 58 (Prss58), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592739.1

ORF Insert Sequence:

ATGAAGTTAG TCTTCTGCAT TCTTTCAACC CTGCTTGGTA CCTTTGCCTA TAATCCAGAT 
CACATAGCTG GCACCACTCC CCCCTACTTA GTCTACCTGA AGTCTGATTA CTTGCCCTGT 
ACTGGAGTCC TGATCCATCC TCTTTGGGTG GTCACATCTG CACACTGCAA TTTACCGGAC 
CTCCGGGTGA TTCTTGGGAT AACAAACCCA GCAGATACCA CAGAACATGA CGTGGAGGTG 
TCTGACTATG AGAAAATGTT CCGTCATCCA TACTTCTCGG TCTCTTCTAT TTCATATGAC 
CTTATGTTAA TCAAACTGAG AAGAGGGATT AAGCACAGTT ACTATGCAAA AGCAGTCAAG 
CTACCTCAAC ACACTGTGCC TGTGAATGCC ATGTGCTCTG TGTCTACCTG GGCCTACAAT 
CTATGTGACG TCACCAAGGA ACCTGACTCA CTGCAGACTG TGAACGTCTC TGTAATCTCC 
AAGGCTGAGT GTCATAATGC CTATAAAGCC TTTGACATCC GAGAAAACAT GATCTGTGTG 
GGCATCGTGC CAGGACGGAG GCTGCCCTGC AAGGAAGTCA CGGCTGCCCC AGCGGTCTGC 
AATGGGGTAC TTTATGGAAT ATTATCTTAT GCAGATGGCT GCGTTTTGAG AGCTGATGTT 
GGCATCTATG CTAGCATCTT TCACTACATG CCCTGGATTG AAAATATCAT GAAAAATAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Long-term nicotine exposure causes increased concentrations of trypsinogens and amylase in pancreatic extracts in the rat.
Pancreas37(3)288-94(2008 Oct)
Lindkvist B,Wierup N,Sundler F,Borgstr?m A

A genomic analysis of rat proteases and protease inhibitors.
Genome research14(4)609-22(2004 Apr)
Puente XS,L?pez-Ot?n C