Abcd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcd1
Entrez Gene ID	363516
Full Name	ATP binding cassette subfamily D member 1
Synonyms	RGD1562128
General protein information	Preferred Names ATP binding cassette subfamily D member 1 Names ATP-binding cassette sub-family D member 1 ATP-binding cassette, sub-family D (ALD), member 1 ATP-binding cassette, subfamily D (ALD), member 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq37

mRNA and Protein(s)

mRNA	Protein	Name
XM_017602115.1	XP_017457604.1	ATP-binding cassette sub-family D member 1 isoform X1
NM_001108821.1	NP_001102291.1	ATP-binding cassette sub-family D member 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	abcd1	NP_001104656.1
	ABCD1	XP_001085640.1
Canis lupus familiaris (dog)	ABCD1	XP_005642054.1
Neurospora crassa	NCU01751	XP_957174.1
Bos taurus (cattle)	ABCD1	NP_001039655.1
Pan troglodytes (chimpanzee)	ABCD1	XP_003317819.1
Magnaporthe oryzae (rice blast fungus)	MGG_06707	XP_003709418.1
Homo sapiens (human)	ABCD1	NP_000024.2
Mus musculus (house mouse)	Abcd1	NP_031461.1
Rattus norvegicus (Norway rat)	Abcd1	NP_001102291.1
Xenopus tropicalis (tropical clawed frog)	abcd1	XP_002935559.1

Gene Ontology
Bibliography

Related articles in PubMed

Peroxisomal ATP-binding cassette transporters form mainly tetramers.
Geillon F, Gondcaille C, Raas Q, Dias AMM, Pecqueur D, Truntzer C, Lucchi G, Ducoroy P, Falson P, Savary S, Trompier D
The Journal of biological chemistry292(17)6965-6977(2017 04)

Brain microsomal fatty acid elongation is increased in abcd1-deficient mouse during active myelination phase.
Morita M, Kawamichi M, Shimura Y, Kawaguchi K, Watanabe S, Imanaka T
Metabolic brain disease30(6)1359-67(2015 Dec)

Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions.
Kruska N, Sch?nfeld P, Pujol A, Reiser G
Biochimica et biophysica acta1852(5)925-36(2015 May)

Structure-function analysis of peroxisomal ATP-binding cassette transporters using chimeric dimers.
Geillon F, Gondcaille C, Charbonnier S, Van Roermund CW, Lopez TE, Dias AM, Pais de Barros JP, Arnould C, Wanders RJ, Trompier D, Savary S
The Journal of biological chemistry289(35)24511-20(2014 Aug)

Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice.
Muneer Z, Wiesinger C, Voigtl?nder T, Werner HB, Berger J, Forss-Petter S
PloS one9(9)e108655(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ABCD1 and its homolog ABCD2 exist mainly as homotetramers in the peroxisomal membrane
Title: Peroxisomal ATP-binding cassette transporters form mainly tetramers.

Substrate specificity overlap and interaction between adrenoleukodystrophy protein (ALDP/ABCD1) and adrenoleukodystrophy-related protein (ALDRP/ABCD2).
Title: Substrate specificity overlap and interaction between adrenoleukodystrophy protein (ALDP/ABCD1) and adrenoleukodystrophy-related protein (ALDRP/ABCD2).

The following Abcd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08432	NM_001108821.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily D member 1 (Abcd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$433.30 $619.00
ORa63084	XM_017602115.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily D member 1 (Abcd1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcd1 ( NM_001108821.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102291.1 Rattus norvegicus ATP binding cassette subfamily D member 1 (Abcd1), mRNA.

Price & Availability↑

CloneID	ORa08432
Clone ID Related Accession (Same CDS sequence)	NM_001108821.1
Accession Version	NM_001108821.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2214bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	ATP-binding cassette sub-family D member 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474099.1. On or before Oct 4, 2007 this sequence version replaced XM_001059399.1, XM_343840.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCGGTAC TCTCCACTCC CTCCCGGCCC TCGCGGGTGA CCACGCTTAA GCGCACAGCT 
GTGGTCCTGG CCCTCACAGC CTATGGAGTC CACAAAATCT ACCCTCTAGT ACGGCAGTGT 
CTGACTCCTG CCAGAGGTCC TCAGGTGCCA GCTGGGGAGT CCACGCAAGA GGCCTCTGGG 
GCCACCACAG CCAAGGCTGG CATGAACCGG GTATTCCTGC AGCGGCTCCT GGTGCTCCTG 
AGGCTGCTGT TCCCCGGAGT CTTGTGCCGG GAAACAGGGC TACTGGCCCT GCATTCTGCT 
GCCCTGGTAA GCCGAACTTT CCTGTCTGTG TATGTTGCCC GCCTGGACGG CAGACTGGCC 
CGCTGCATTG TACGTAAGGA CCCAAGGGCC TTTAGCTGGC AACTGCTGCA GTGGCTCCTC 
ATCGCCCTTC CTGCCACTTT CATCAACAGT GCCATCCGCT ACCTAGAGGG CCAGCTGGCT 
CTTTCTTTCC GAAGCCGTCT AGTAGCTCAT GCCTATGGCC TCTACTTCTC CCAGCAGACT 
TACTACCGAG TAAGCAACAT GGATGGACGG CTTCGAAACC CTGACCAGTC TCTGACAGAG 
GATATGGTAG CCTTTGCTGC TTCTGTAGCC CACCTTTATT CCAACCTGAC CAAGCCACTC 
CTGGATGTGG CTGTGACCTC CTACACTCTT CTTCGAGCTG CCCGATCCCG AGGAGCTGGT 
ACAGCCTGGC CCTCAGCCAT CGCTGGCCTG GTGGTGTTCC TCACAGCCAA CGTGCTTCGA 
GCCTTCTCTC CCAAGTTTGG GGAGCTAGTG GCAGAGGAGG CACGGCGAAA GGGGGAACTG 
CGCTACATGC ACTCTCGAGT GGTGGCCAAC TCAGAGGAAA TTGCCTTCTA CGGGGGCCAT 
GAGGTAGAGC TGGCACTACT ACAACACTCC TATCAAGACC TGGCTTCACA GATCAACCTC 
ATCCTCCTAG AACGCCTGTG GTATGTCATG CTAGAACAGT TCCTCATGAA ATATGTGTGG 
AGTGCATCTG GCCTGCTCAT GGTAGCTGTC CCCATCATCA CAGCCACTGG CTATGCAGAG 
TCAGACTCAG AAGCCATGAA AAAGGCAGCC TTAGAAATGA AGGAAGAGGA GCTGGTTAGT 
GAACGTACAG AAGCCTTCAC CATTGCCCGA AACCTCCTCA CAGCTGCTGC AGATGCCACT 
GAGAGGATCA TGTCATCCTA CAAGGAGGTG ACAGAGCTGG CTGGCTACAC AGCCAGGGTG 
TACGAGATGT TCCAGGTATT TGAAGATGTC CAACACTGTC GTTTTAAGAG GACAGGAGAT 
CTAGAGGAGG CTCAGGCTGG GCCTGGGTCC ATGGTGCATT CTGGTGTTCA TATAGAAGGG 
CCCCTGAAGA TCCAAGGCCA GGTGGTGGAT GTGGAGCAGG GGATCATCTG TGAGAACATC 
CCTATCATCA CACCCACTGG AGAGGTGGTG GTGGCCAGCC TCAACATCAG GGTGGAGGAA 
GGCATGCACC TGCTCATCAC AGGCCCCAAT GGCTGCGGCA AGAGTTCTCT GTTCCGAATC 
CTAGGTGGAC TCTGGCCAAC ATACAGTGGG GTACTCTATA AGCCCCCACC CCAGCGCATG 
TTCTATATCC CTCAGAGGCC CTACATGTCC GTGGGCTCCT TGCGTGACCA AGTGATCTAT 
CCTGACTCTG CGGAAGACAT GCGGAGGAAG GGCTGCTCGG AGCAGCAGCT GGAAGCCATC 
CTGGGCATCG TGCATCTCCG ACACATCCTG CAACGGGAGG GAGGTTGGGA GGCTGTGTGT 
GACTGGAAGG ACGTCCTTTC TGGTGGTGAG AAGCAGAGGA TTGGTATGGC GCGCATGTTC 
TATCACAGGC CCAAGTACGC CCTCCTGGAT GAGTGCACTA GTGCCGTGAG CATTGATGTG 
GAAGGCAAGA TCTTCCAAGC AGCCAAAGAT GCTGGTATCT CACTGCTGTC CATCACCCAT 
CGACCCTCCC TATGGAAGTA CCACACACAC TTGCTGCAGT TTGATGGGGA GGGAGGCTGG 
AAGTTTGAGA AGCTGGATTC TGCTGCCCGC CTGAGCCTGA CTGAAGAGAA GCAGCGCCTG 
GAGCAGCAAC TGGCAGGCAT CCCTAAGATG CAGGGGCGCC TTCAGGAGCT CCGCCAGATC 
CTTGGCGAAG CTGCAGCCCC AGTTCAACCT CTGGTCCCAG GCATCCCCAC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102291.1
CDS	435..2648
Translation	MPVLSTPSRPSRVTTLKRTAVVLALTAYGVHKIYPLVRQCLTPARGPQVPAGESTQEASGATTAKAGMNRVFLQRLLVLLRLLFPGVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDMVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVQHCRFKRTGDLEEAQAGPGSMVHSGVHIEGPLKIQGQVVDVEQGIICENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYSGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRHILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQGRLQELRQILGEAAAPVQPLVPGIPT

Target ORF information:

RefSeq Version	NM_001108821.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily D member 1 (Abcd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108821.1

ORF Insert Sequence:

ATGCCGGTAC TCTCCACTCC CTCCCGGCCC TCGCGGGTGA CCACGCTTAA GCGCACAGCT 
GTGGTCCTGG CCCTCACAGC CTATGGAGTC CACAAAATCT ACCCTCTAGT ACGGCAGTGT 
CTGACTCCTG CCAGAGGTCC TCAGGTGCCA GCTGGGGAGT CCACGCAAGA GGCCTCTGGG 
GCCACCACAG CCAAGGCTGG CATGAACCGG GTATTCCTGC AGCGGCTCCT GGTGCTCCTG 
AGGCTGCTGT TCCCCGGAGT CTTGTGCCGG GAAACAGGGC TACTGGCCCT GCATTCTGCT 
GCCCTGGTAA GCCGAACTTT CCTGTCTGTG TATGTTGCCC GCCTGGACGG CAGACTGGCC 
CGCTGCATTG TACGTAAGGA CCCAAGGGCC TTTAGCTGGC AACTGCTGCA GTGGCTCCTC 
ATCGCCCTTC CTGCCACTTT CATCAACAGT GCCATCCGCT ACCTAGAGGG CCAGCTGGCT 
CTTTCTTTCC GAAGCCGTCT AGTAGCTCAT GCCTATGGCC TCTACTTCTC CCAGCAGACT 
TACTACCGAG TAAGCAACAT GGATGGACGG CTTCGAAACC CTGACCAGTC TCTGACAGAG 
GATATGGTAG CCTTTGCTGC TTCTGTAGCC CACCTTTATT CCAACCTGAC CAAGCCACTC 
CTGGATGTGG CTGTGACCTC CTACACTCTT CTTCGAGCTG CCCGATCCCG AGGAGCTGGT 
ACAGCCTGGC CCTCAGCCAT CGCTGGCCTG GTGGTGTTCC TCACAGCCAA CGTGCTTCGA 
GCCTTCTCTC CCAAGTTTGG GGAGCTAGTG GCAGAGGAGG CACGGCGAAA GGGGGAACTG 
CGCTACATGC ACTCTCGAGT GGTGGCCAAC TCAGAGGAAA TTGCCTTCTA CGGGGGCCAT 
GAGGTAGAGC TGGCACTACT ACAACACTCC TATCAAGACC TGGCTTCACA GATCAACCTC 
ATCCTCCTAG AACGCCTGTG GTATGTCATG CTAGAACAGT TCCTCATGAA ATATGTGTGG 
AGTGCATCTG GCCTGCTCAT GGTAGCTGTC CCCATCATCA CAGCCACTGG CTATGCAGAG 
TCAGACTCAG AAGCCATGAA AAAGGCAGCC TTAGAAATGA AGGAAGAGGA GCTGGTTAGT 
GAACGTACAG AAGCCTTCAC CATTGCCCGA AACCTCCTCA CAGCTGCTGC AGATGCCACT 
GAGAGGATCA TGTCATCCTA CAAGGAGGTG ACAGAGCTGG CTGGCTACAC AGCCAGGGTG 
TACGAGATGT TCCAGGTATT TGAAGATGTC CAACACTGTC GTTTTAAGAG GACAGGAGAT 
CTAGAGGAGG CTCAGGCTGG GCCTGGGTCC ATGGTGCATT CTGGTGTTCA TATAGAAGGG 
CCCCTGAAGA TCCAAGGCCA GGTGGTGGAT GTGGAGCAGG GGATCATCTG TGAGAACATC 
CCTATCATCA CACCCACTGG AGAGGTGGTG GTGGCCAGCC TCAACATCAG GGTGGAGGAA 
GGCATGCACC TGCTCATCAC AGGCCCCAAT GGCTGCGGCA AGAGTTCTCT GTTCCGAATC 
CTAGGTGGAC TCTGGCCAAC ATACAGTGGG GTACTCTATA AGCCCCCACC CCAGCGCATG 
TTCTATATCC CTCAGAGGCC CTACATGTCC GTGGGCTCCT TGCGTGACCA AGTGATCTAT 
CCTGACTCTG CGGAAGACAT GCGGAGGAAG GGCTGCTCGG AGCAGCAGCT GGAAGCCATC 
CTGGGCATCG TGCATCTCCG ACACATCCTG CAACGGGAGG GAGGTTGGGA GGCTGTGTGT 
GACTGGAAGG ACGTCCTTTC TGGTGGTGAG AAGCAGAGGA TTGGTATGGC GCGCATGTTC 
TATCACAGGC CCAAGTACGC CCTCCTGGAT GAGTGCACTA GTGCCGTGAG CATTGATGTG 
GAAGGCAAGA TCTTCCAAGC AGCCAAAGAT GCTGGTATCT CACTGCTGTC CATCACCCAT 
CGACCCTCCC TATGGAAGTA CCACACACAC TTGCTGCAGT TTGATGGGGA GGGAGGCTGG 
AAGTTTGAGA AGCTGGATTC TGCTGCCCGC CTGAGCCTGA CTGAAGAGAA GCAGCGCCTG 
GAGCAGCAAC TGGCAGGCAT CCCTAAGATG CAGGGGCGCC TTCAGGAGCT CCGCCAGATC 
CTTGGCGAAG CTGCAGCCCC AGTTCAACCT CTGGTCCCAG GCATCCCCAC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcd1 ( XM_017602115.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457604.1 Rattus norvegicus ATP binding cassette subfamily D member 1 (Abcd1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa63084
Clone ID Related Accession (Same CDS sequence)	XM_017602115.1
Accession Version	XM_017602115.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2184bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ATP-binding cassette sub-family D member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGTAC TCTCCACTCC CTCCCGGCCC TCGCGGGTGA CCACGCTTAA GCGCACAGCT 
GTGGTCCTGG CCCTCACAGC CTATGGAGTC CACAAAATCT ACCCTCTAGT ACGGCAGTGT 
CTGACTCCTG CCAGAGGTCC TCAGGTGCCA GCTGGGGAGT CCACGCAAGA GGCCTCTGGG 
GCCACCACAG CCAAGGCTGG CATGAACCGG GTATTCCTGC AGCGGCTCCT GGTGCTCCTG 
AGGCTGCTGT TCCCCGGAGT CTTGTGCCGG GAAACAGGGC TACTGGCCCT GCATTCTGCT 
GCCCTGGTAA GCCGAACTTT CCTGTCTGTG TATGTTGCCC GCCTGGACGG CAGACTGGCC 
CGCTGCATTG TACGTAAGGA CCCAAGGGCC TTTAGCTGGC AACTGCTGCA GTGGCTCCTC 
ATCGCCCTTC CTGCCACTTT CATCAACAGT GCCATCCGCT ACCTAGAGGG CCAGCTGGCT 
CTTTCTTTCC GAAGCCGTCT AGTAGCTCAT GCCTATGGCC TCTACTTCTC CCAGCAGACT 
TACTACCGAG TAAGCAACAT GGATGGACGG CTTCGAAACC CTGACCAGTC TCTGACAGAG 
GATATGGTAG CCTTTGCTGC TTCTGTAGCC CACCTTTATT CCAACCTGAC CAAGCCACTC 
CTGGATGTGG CTGTGACCTC CTACACTCTT CTTCGAGCTG CCCGATCCCG AGGAGCTGGT 
ACAGCCTGGC CCTCAGCCAT CGCTGGCCTG GTGGTGTTCC TCACAGCCAA CGTGCTTCGA 
GCCTTCTCTC CCAAGTTTGG GGAGCTAGTG GCAGAGGAGG CACGGCGAAA GGGGGAACTG 
CGCTACATGC ACTCTCGAGT GGTGGCCAAC TCAGAGGAAA TTGCCTTCTA CGGGGGCCAT 
GAGGTAGAGC TGGCACTACT ACAACACTCC TATCAAGACC TGGCTTCACA GATCAACCTC 
ATCCTCCTAG AACGCCTGTG GTATGTCATG CTAGAACAGT TCCTCATGAA ATATGTGTGG 
AGTGCATCTG GCCTGCTCAT GGTAGCTGTC CCCATCATCA CAGCCACTGG CTATGCAGAG 
TCAGAAATGA AGGAAGAGGA GCTGGTTAGT GAACGTACAG AAGCCTTCAC CATTGCCCGA 
AACCTCCTCA CAGCTGCTGC AGATGCCACT GAGAGGATCA TGTCATCCTA CAAGGAGGTG 
ACAGAGCTGG CTGGCTACAC AGCCAGGGTG TACGAGATGT TCCAGGTATT TGAAGATGTC 
CAACACTGTC GTTTTAAGAG GACAGGAGAT CTAGAGGAGG CTCAGGCTGG GCCTGGGAAA 
GCAGCAAAAT GCTGTGCTCC TGTATTTCCA TGCCTTCTCT CTACAGGCCA GGTGGTGGAT 
GTGGAGCAGG GGATCATCTG TGAGAACATC CCTATCATCA CACCCACTGG AGAGGTGGTG 
GTGGCCAGCC TCAACATCAG GGTGGAGGAA GGCATGCACC TGCTCATCAC AGGCCCCAAT 
GGCTGCGGCA AGAGTTCTCT GTTCCGAATC CTAGGTGGAC TCTGGCCAAC ATACAGTGGG 
GTACTCTATA AGCCCCCACC CCAGCGCATG TTCTATATCC CTCAGAGGCC CTACATGTCC 
GTGGGCTCCT TGCGTGACCA AGTGATCTAT CCTGACTCTG CGGAAGACAT GCGGAGGAAG 
GGCTGCTCGG AGCAGCAGCT GGAAGCCATC CTGGGCATCG TGCATCTCCG ACACATCCTG 
CAACGGGAGG GAGGTTGGGA GGCTGTGTGT GACTGGAAGG ACGTCCTTTC TGGTGGTGAG 
AAGCAGAGGA TTGGTATGGC GCGCATGTTC TATCACAGGC CCAAGTACGC CCTCCTGGAT 
GAGTGCACTA GTGCCGTGAG CATTGATGTG GAAGGCAAGA TCTTCCAAGC AGCCAAAGAT 
GCTGGTATCT CACTGCTGTC CATCACCCAT CGACCCTCCC TATGGAAGTA CCACACACAC 
TTGCTGCAGT TTGATGGGGA GGGAGGCTGG AAGTTTGAGA AGCTGGATTC TGCTGCCCGC 
CTGAGCCTGA CTGAAGAGAA GCAGCGCCTG GAGCAGCAAC TGGCAGGCAT CCCTAAGATG 
CAGGGGCGCC TTCAGGAGCT CCGCCAGATC CTTGGCGAAG CTGCAGCCCC AGTTCAACCT 
CTGGTCCCAG GCATCCCCAC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457604.1
CDS	576..2759
Translation	MPVLSTPSRPSRVTTLKRTAVVLALTAYGVHKIYPLVRQCLTPARGPQVPAGESTQEASGATTAKAGMNRVFLQRLLVLLRLLFPGVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDMVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVQHCRFKRTGDLEEAQAGPGKAAKCCAPVFPCLLSTGQVVDVEQGIICENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYSGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRHILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQGRLQELRQILGEAAAPVQPLVPGIPT

Target ORF information:

RefSeq Version	XM_017602115.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily D member 1 (Abcd1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017602115.1

ORF Insert Sequence:

ATGCCGGTAC TCTCCACTCC CTCCCGGCCC TCGCGGGTGA CCACGCTTAA GCGCACAGCT 
GTGGTCCTGG CCCTCACAGC CTATGGAGTC CACAAAATCT ACCCTCTAGT ACGGCAGTGT 
CTGACTCCTG CCAGAGGTCC TCAGGTGCCA GCTGGGGAGT CCACGCAAGA GGCCTCTGGG 
GCCACCACAG CCAAGGCTGG CATGAACCGG GTATTCCTGC AGCGGCTCCT GGTGCTCCTG 
AGGCTGCTGT TCCCCGGAGT CTTGTGCCGG GAAACAGGGC TACTGGCCCT GCATTCTGCT 
GCCCTGGTAA GCCGAACTTT CCTGTCTGTG TATGTTGCCC GCCTGGACGG CAGACTGGCC 
CGCTGCATTG TACGTAAGGA CCCAAGGGCC TTTAGCTGGC AACTGCTGCA GTGGCTCCTC 
ATCGCCCTTC CTGCCACTTT CATCAACAGT GCCATCCGCT ACCTAGAGGG CCAGCTGGCT 
CTTTCTTTCC GAAGCCGTCT AGTAGCTCAT GCCTATGGCC TCTACTTCTC CCAGCAGACT 
TACTACCGAG TAAGCAACAT GGATGGACGG CTTCGAAACC CTGACCAGTC TCTGACAGAG 
GATATGGTAG CCTTTGCTGC TTCTGTAGCC CACCTTTATT CCAACCTGAC CAAGCCACTC 
CTGGATGTGG CTGTGACCTC CTACACTCTT CTTCGAGCTG CCCGATCCCG AGGAGCTGGT 
ACAGCCTGGC CCTCAGCCAT CGCTGGCCTG GTGGTGTTCC TCACAGCCAA CGTGCTTCGA 
GCCTTCTCTC CCAAGTTTGG GGAGCTAGTG GCAGAGGAGG CACGGCGAAA GGGGGAACTG 
CGCTACATGC ACTCTCGAGT GGTGGCCAAC TCAGAGGAAA TTGCCTTCTA CGGGGGCCAT 
GAGGTAGAGC TGGCACTACT ACAACACTCC TATCAAGACC TGGCTTCACA GATCAACCTC 
ATCCTCCTAG AACGCCTGTG GTATGTCATG CTAGAACAGT TCCTCATGAA ATATGTGTGG 
AGTGCATCTG GCCTGCTCAT GGTAGCTGTC CCCATCATCA CAGCCACTGG CTATGCAGAG 
TCAGAAATGA AGGAAGAGGA GCTGGTTAGT GAACGTACAG AAGCCTTCAC CATTGCCCGA 
AACCTCCTCA CAGCTGCTGC AGATGCCACT GAGAGGATCA TGTCATCCTA CAAGGAGGTG 
ACAGAGCTGG CTGGCTACAC AGCCAGGGTG TACGAGATGT TCCAGGTATT TGAAGATGTC 
CAACACTGTC GTTTTAAGAG GACAGGAGAT CTAGAGGAGG CTCAGGCTGG GCCTGGGAAA 
GCAGCAAAAT GCTGTGCTCC TGTATTTCCA TGCCTTCTCT CTACAGGCCA GGTGGTGGAT 
GTGGAGCAGG GGATCATCTG TGAGAACATC CCTATCATCA CACCCACTGG AGAGGTGGTG 
GTGGCCAGCC TCAACATCAG GGTGGAGGAA GGCATGCACC TGCTCATCAC AGGCCCCAAT 
GGCTGCGGCA AGAGTTCTCT GTTCCGAATC CTAGGTGGAC TCTGGCCAAC ATACAGTGGG 
GTACTCTATA AGCCCCCACC CCAGCGCATG TTCTATATCC CTCAGAGGCC CTACATGTCC 
GTGGGCTCCT TGCGTGACCA AGTGATCTAT CCTGACTCTG CGGAAGACAT GCGGAGGAAG 
GGCTGCTCGG AGCAGCAGCT GGAAGCCATC CTGGGCATCG TGCATCTCCG ACACATCCTG 
CAACGGGAGG GAGGTTGGGA GGCTGTGTGT GACTGGAAGG ACGTCCTTTC TGGTGGTGAG 
AAGCAGAGGA TTGGTATGGC GCGCATGTTC TATCACAGGC CCAAGTACGC CCTCCTGGAT 
GAGTGCACTA GTGCCGTGAG CATTGATGTG GAAGGCAAGA TCTTCCAAGC AGCCAAAGAT 
GCTGGTATCT CACTGCTGTC CATCACCCAT CGACCCTCCC TATGGAAGTA CCACACACAC 
TTGCTGCAGT TTGATGGGGA GGGAGGCTGG AAGTTTGAGA AGCTGGATTC TGCTGCCCGC 
CTGAGCCTGA CTGAAGAGAA GCAGCGCCTG GAGCAGCAAC TGGCAGGCAT CCCTAAGATG 
CAGGGGCGCC TTCAGGAGCT CCGCCAGATC CTTGGCGAAG CTGCAGCCCC AGTTCAACCT 
CTGGTCCCAG GCATCCCCAC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Peroxisomal ATP-binding cassette transporters form mainly tetramers.
The Journal of biological chemistry292(17)6965-6977(2017 04)
Geillon F,Gondcaille C,Raas Q,Dias AMM,Pecqueur D,Truntzer C,Lucchi G,Ducoroy P,Falson P,Savary S,Trompier D

Brain microsomal fatty acid elongation is increased in abcd1-deficient mouse during active myelination phase.
Metabolic brain disease30(6)1359-67(2015 Dec)
Morita M,Kawamichi M,Shimura Y,Kawaguchi K,Watanabe S,Imanaka T

Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions.
Biochimica et biophysica acta1852(5)925-36(2015 May)
Kruska N,Sch?nfeld P,Pujol A,Reiser G

Structure-function analysis of peroxisomal ATP-binding cassette transporters using chimeric dimers.
The Journal of biological chemistry289(35)24511-20(2014 Aug)
Geillon F,Gondcaille C,Charbonnier S,Van Roermund CW,Lopez TE,Dias AM,Pais de Barros JP,Arnould C,Wanders RJ,Trompier D,Savary S

Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice.
PloS one9(9)e108655(2014)
Muneer Z,Wiesinger C,Voigtl?nder T,Werner HB,Berger J,Forss-Petter S