Eif4e2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif4e2
Entrez Gene ID	363275
Full Name	eukaryotic translation initiation factor 4E family member 2
Synonyms	Eif4el3
General protein information	Preferred Names eukaryotic translation initiation factor 4E family member 2 Names eukaryotic translation initiation factor 4E type 2 eukaryotic translation initiation factor 4E like 3 eukaryotic translation initiation factor 4E member 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q35

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108808.1	NP_001102278.1	eukaryotic translation initiation factor 4E type 2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development.
Morita M, Ler LW, Fabian MR, Siddiqui N, Mullin M, Henderson VC, Alain T, Fonseca BD, Karashchuk G, Bennett CF, Kabuta T, Higashi S, Larsson O, Topisirovic I, Smith RJ, Gingras AC, Sonenberg N
Molecular and cellular biology32(17)3585-93(2012 Sep)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
Rosettani P, Knapp S, Vismara MG, Rusconi L, Cameron AD
Journal of molecular biology368(3)691-705(2007 May)

Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP.
Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA
FEBS letters554(3)501-4(2003 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eif4e2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif4e2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11846	NM_001108808.1 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 4E family member 2 (Eif4e2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif4e2 ( NM_001108808.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102278.1 Rattus norvegicus eukaryotic translation initiation factor 4E family member 2 (Eif4e2), mRNA.

Price & Availability↑

CloneID	ORa11846
Clone ID Related Accession (Same CDS sequence)	NM_001108808.1
Accession Version	NM_001108808.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 4E type 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474004.1. On or before Oct 4, 2007 this sequence version replaced XM_001081452.1, XM_343616.2. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGATGACAG TGGAGACCAT GATCAGAATG AAGAAAACAG CACACAGAAA GATGGTGAGA 
AGGAAAAAAC AGACCGAGAT AAGAGCCAGA GTGGTGGAAC AGTTCTGGAA GTTTTACAGC 
CACATGGTCC GTCCCGGGGA CCTGACAGGC CACAGTGACT TTCATCTCTT TAAAGAAGGA 
ATCAAACCTA TGTGGGAGGA TGATGCAAAT AAAAATGGGG GCAAGTGGAT CATTCGACTC 
CGGAAGGGCT TAGCTTCCCG CTGCTGGGAG AATCTCATCC TGGCCATGCT CGGGGAACAG 
TTCATGGTTG GGGAGGAGAT CTGCGGGGCT GTGGTCTCTG TCCGCTTCCA GGAGGACATT 
ATTTCTATAT GGAATAAGAC TGCCAGCGAC CAAGCAACCA CAGCCCGAAT CCGGGACACT 
CTTCGGCGCG TGCTTAACCT ACCTCCCAAC ACCATTATGG AATACAAAAC TCACACCGAC 
AGCATCAAGT ACGTGTTGGG GGGTTTGGGG GGGACAGGTC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102278.1
CDS	590..1114
Translation	MMTVETMIRMKKTAHRKMVRRKKQTEIRARVVEQFWKFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKYVLGGLGGTGP

Target ORF information:

RefSeq Version	NM_001108808.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 4E family member 2 (Eif4e2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108808.1

ORF Insert Sequence:

ATGATGACAG TGGAGACCAT GATCAGAATG AAGAAAACAG CACACAGAAA GATGGTGAGA 
AGGAAAAAAC AGACCGAGAT AAGAGCCAGA GTGGTGGAAC AGTTCTGGAA GTTTTACAGC 
CACATGGTCC GTCCCGGGGA CCTGACAGGC CACAGTGACT TTCATCTCTT TAAAGAAGGA 
ATCAAACCTA TGTGGGAGGA TGATGCAAAT AAAAATGGGG GCAAGTGGAT CATTCGACTC 
CGGAAGGGCT TAGCTTCCCG CTGCTGGGAG AATCTCATCC TGGCCATGCT CGGGGAACAG 
TTCATGGTTG GGGAGGAGAT CTGCGGGGCT GTGGTCTCTG TCCGCTTCCA GGAGGACATT 
ATTTCTATAT GGAATAAGAC TGCCAGCGAC CAAGCAACCA CAGCCCGAAT CCGGGACACT 
CTTCGGCGCG TGCTTAACCT ACCTCCCAAC ACCATTATGG AATACAAAAC TCACACCGAC 
AGCATCAAGT ACGTGTTGGG GGGTTTGGGG GGGACAGGTC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development.
Molecular and cellular biology32(17)3585-93(2012 Sep)
Morita M,Ler LW,Fabian MR,Siddiqui N,Mullin M,Henderson VC,Alain T,Fonseca BD,Karashchuk G,Bennett CF,Kabuta T,Higashi S,Larsson O,Topisirovic I,Smith RJ,Gingras AC,Sonenberg N

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
Journal of molecular biology368(3)691-705(2007 May)
Rosettani P,Knapp S,Vismara MG,Rusconi L,Cameron AD

Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP.
FEBS letters554(3)501-4(2003 Nov)
Tan NG,Ardley HC,Scott GB,Rose SA,Markham AF,Robinson PA