The following Nlrp1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nlrp1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa04539 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001145755.2 , XM_006246755.3 | |
| Accession Version | NM_001145755.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3657bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-11-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | NACHT, LRR and PYD domains-containing protein 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC095695.10. On Feb 16, 2013 this sequence version replaced NM_001145755.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HM060628.1, HM060629.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGAAGAAT CTCAGTCCAA GCAGGAAAGT AACACAAGGG TGGCTCAGCA TGGAAGCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001139227.2 |
| CDS | 43..3699 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001145755.2 |
1 | ATGGAAGAAT CTCAGTCCAA GCAGGAAAGT AACACAAGGG TGGCTCAGCA TGGAAGCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa04539 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001145755.2 , XM_006246755.3 | |
| Accession Version | XM_006246755.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3657bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | NACHT, LRR and PYD domains-containing protein 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006246755.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGAAGAAT CTCAGTCCAA GCAGGAAAGT AACACAAGGG TGGCTCAGCA TGGAAGCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006246817.1 |
| CDS | 332..3988 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006246755.3 |
1 | ATGGAAGAAT CTCAGTCCAA GCAGGAAAGT AACACAAGGG TGGCTCAGCA TGGAAGCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation. |
Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1? production in acute glaucoma. |
A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage. |
Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii. |
