Cyp11b3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cyp11b3
Entrez Gene ID	353498
Full Name	cytochrome P450, family 11, subfamily b, polypeptide 3
Synonyms	CYPXIB3
General protein information	Preferred Names cytochrome P450, family 11, subfamily b, polypeptide 3 Names cytochrome P450, family 11, subfamily b, polypeptide 3 cytochrome P450, subfamily 11B, polypeptide 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q34
Summary	member of the cytochrome P450 superfamily of enzymes; monooxygenase enzyme with 11-hydroxylase and 18-hydroxylase activity [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008765572.2	XP_008763794.1	cytochrome P450, family 11, subfamily b, polypeptide 3 isoform X1
NM_181824.1	NP_861545.1	cytochrome P450, family 11, subfamily b, polypeptide 3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CYP11B1	XP_005215349.1
Rattus norvegicus (Norway rat)	LOC100910462	XP_003750411.2
	CYP11B2	XP_001085034.1
Canis lupus familiaris (dog)	CYP11B2	XP_539192.3
Rattus norvegicus (Norway rat)	Cyp11b3	NP_861545.1
Homo sapiens (human)	CYP11B2	NP_000489.3
Mus musculus (house mouse)	Cyp11b1	NP_001028401.2

Gene Ontology
Bibliography

Related articles in PubMed

Structural insights into aldosterone synthase substrate specificity and targeted inhibition.
Strushkevich N, Gilep AA, Shen L, Arrowsmith CH, Edwards AM, Usanov SA, Park HW
Molecular endocrinology (Baltimore, Md.)27(2)315-24(2013 Feb)

Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor.
Somekawa S, Imagawa K, Naya N, Takemoto Y, Onoue K, Okayama S, Takeda Y, Kawata H, Horii M, Nakajima T, Uemura S, Mochizuki N, Saito Y
Endocrinology150(7)3110-7(2009 Jul)

A missense mutation (GGC[435Gly]-->AGC[Ser]) in exon 8 of the CYP11B2 gene inherited in Japanese patients with congenital hypoaldosteronism.
Kuribayashi I, Kuge H, Santa RJ, Mutlaq AZ, Yamasaki N, Furuno T, Takahashi A, Chida S, Nakamura T, Endo F, Doi Y, Onishi S, Shizuta Y
Hormone research60(5)255-60(2003)

An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy.
Tiago AD, Badenhorst D, Skudicky D, Woodiwiss AJ, Candy GP, Brooksbank R, Sliwa K, Sareli P, Norton GR
Cardiovascular research54(3)584-9(2002 Jun)

Genetic variation in aldosterone synthase predicts plasma glucose levels.
Ranade K, Wu KD, Risch N, Olivier M, Pei D, Hsiao CF, Chuang LM, Ho LT, Jorgenson E, Pesich R, Chen YD, Dzau V, Lin A, Olshen RA, Curb D, Cox DR, Botstein D
Proceedings of the National Academy of Sciences of the United States of America98(23)13219-24(2001 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cyp11b3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cyp11b3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42036	NM_181824.1 Latest version!	Rattus norvegicus cytochrome P450, family 11, subfamily b, polypeptide 3 (Cyp11b3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa47653	XM_008765572.2 Latest version!	Rattus norvegicus cytochrome P450, family 11, subfamily b, polypeptide 3 (Cyp11b3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cyp11b3 ( NM_181824.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_861545.1 Rattus norvegicus cytochrome P450, family 11, subfamily b, polypeptide 3 (Cyp11b3), mRNA.

Price & Availability↑

CloneID	ORa42036
Clone ID Related Accession (Same CDS sequence)	NM_181824.1
Accession Version	NM_181824.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1497bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-26
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome P450, family 11, subfamily b, polypeptide 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U14907.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U14907.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCTCTCA GGGTGACAGC AGATGTGTGG GCAAGACCCT GGCAGTGCCT GCACAGGACG 
AGGGCACTGG GCAGTACGGC AACACAGGCC CCCAAGACAC TGAAGCCCTT TGAAGCCATA 
CCACAATACT CCAGGAACAA GTGGCTGAAG ATGATACAGA TCCTGAGGGA GCAGAGCCAA 
GAGAACCTAC ACCTGGAGAT GCACCAGGCC TTCCAGGAAC TAGGGCCCAT TTTCAGGCAC 
AGTGCAGGGG GAGCACAGAT TGTGTCTGTG ATGCTGCCTG AGGACGCTGA GAAGCTGCAC 
CAGGTGGAGA GTATCCTCCC GCGTCGGATG ACGCTGGAGT CGTGGGTGGC CCACAGAGAA 
CTCCGTGGCC TGAGACGTGG TGTGTTCTTG CTAAATGGGG CAGACTGGCG CTTCAACCGA 
CTGCAGCTGA ATCCAAATAT GCTGTCACCA AAAGCCGTTC AATCTTTTGT CCCCTTTGTG 
GATGTGGTAG CAAGGGACTT TGTGGAAAAC CTGAAGAAGA GAATGCTGGA GAATGTTCAT 
GGAAGCATGT CTATGGACAT TCAGTCCAAT GTGTTCAACT ATACCATGGA AGCCAGCCAT 
TTTGTTATTT CCGGAGAGCG ACTGGGCCTC ACAGGCCATG ACCTGAACCC TGAGAGCCTG 
AAGTTCATTC ATGCTCTGCA CTCAATGTTC AAGTCCACCA CACAGCTCAT GTTCTTACCC 
AAGAACTTGA CTCGTTGGAC AAGCACCCAG GTGTGGAAAG GACACTTTGA GTCCTGGGAT 
ATCATCTCTG AGTATGTCAC AAAATGTATC AAGAATGTGT ATCGCGAACT GGCAGAGGGT 
CGCCAACAGT CCTGGAGTGT CATATCCGAG ATGGTAGCAC AGAGTACTCT GTCAATGGAT 
GCCATCCATG CCAACTCAAT GGAACTTATT GCTGGAAGTG TTGACACGAC AGCAATCTCC 
TTGGTAATGA CCCTTTTTGA GCTGGCTCGG AACCCAGATG TTCAGCAGGC CCTGCGGCAG 
GAGAGCCTGG CAGCTGAGGC CAGCATCGCT GCTAATCCCC AGAAGGCCAT GTCAGACTTG 
CCCTTGCTGC GGGCTGCCCT TAAAGAGACC TTGAGGCTCT ACCCCATTGG TAGCTCTTTG 
GAGAGAATCG TAGACTCAGA CCTGGTGCTT CAGAACTATC ATGTCCCTGC TGGGACGTTG 
GTCATAATTT ATCTGTACTC CATGGGCCGA AACCCTGCAG TGTTCCCAAG ACCTGAGCGC 
TACATGCCTC AGCGCTGGCT GGAGAGGAAA AGGAGTTTCC AGCATCTGGC CTTCGGCTTT 
GGGGTGCGCC AGTGCCTGGG GCGGCGCCTG GCAGAGGTGG AGGTGTTGCT CCTGCTTCAC 
CATATGCTGA AAATCTTCCA AGTCGAGACA CTGAGGCAAG AGGATGTGCA GATGGCCTAT 
CGCTTTGTTT TGATGCCCAA CCCTAGACTC GTCCTCACTA TCCGGCCTGT GAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_861545.1
CDS	1..1497
Translation	MALRVTADVWARPWQCLHRTRALGSTATQAPKTLKPFEAIPQYSRNKWLKMIQILREQSQENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPRRMTLESWVAHRELRGLRRGVFLLNGADWRFNRLQLNPNMLSPKAVQSFVPFVDVVARDFVENLKKRMLENVHGSMSMDIQSNVFNYTMEASHFVISGERLGLTGHDLNPESLKFIHALHSMFKSTTQLMFLPKNLTRWTSTQVWKGHFESWDIISEYVTKCIKNVYRELAEGRQQSWSVISEMVAQSTLSMDAIHANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPIGSSLERIVDSDLVLQNYHVPAGTLVIIYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEVLLLLHHMLKIFQVETLRQEDVQMAYRFVLMPNPRLVLTIRPVS

Target ORF information:

RefSeq Version	NM_181824.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 11, subfamily b, polypeptide 3 (Cyp11b3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181824.1

ORF Insert Sequence:

ATGGCTCTCA GGGTGACAGC AGATGTGTGG GCAAGACCCT GGCAGTGCCT GCACAGGACG 
AGGGCACTGG GCAGTACGGC AACACAGGCC CCCAAGACAC TGAAGCCCTT TGAAGCCATA 
CCACAATACT CCAGGAACAA GTGGCTGAAG ATGATACAGA TCCTGAGGGA GCAGAGCCAA 
GAGAACCTAC ACCTGGAGAT GCACCAGGCC TTCCAGGAAC TAGGGCCCAT TTTCAGGCAC 
AGTGCAGGGG GAGCACAGAT TGTGTCTGTG ATGCTGCCTG AGGACGCTGA GAAGCTGCAC 
CAGGTGGAGA GTATCCTCCC GCGTCGGATG ACGCTGGAGT CGTGGGTGGC CCACAGAGAA 
CTCCGTGGCC TGAGACGTGG TGTGTTCTTG CTAAATGGGG CAGACTGGCG CTTCAACCGA 
CTGCAGCTGA ATCCAAATAT GCTGTCACCA AAAGCCGTTC AATCTTTTGT CCCCTTTGTG 
GATGTGGTAG CAAGGGACTT TGTGGAAAAC CTGAAGAAGA GAATGCTGGA GAATGTTCAT 
GGAAGCATGT CTATGGACAT TCAGTCCAAT GTGTTCAACT ATACCATGGA AGCCAGCCAT 
TTTGTTATTT CCGGAGAGCG ACTGGGCCTC ACAGGCCATG ACCTGAACCC TGAGAGCCTG 
AAGTTCATTC ATGCTCTGCA CTCAATGTTC AAGTCCACCA CACAGCTCAT GTTCTTACCC 
AAGAACTTGA CTCGTTGGAC AAGCACCCAG GTGTGGAAAG GACACTTTGA GTCCTGGGAT 
ATCATCTCTG AGTATGTCAC AAAATGTATC AAGAATGTGT ATCGCGAACT GGCAGAGGGT 
CGCCAACAGT CCTGGAGTGT CATATCCGAG ATGGTAGCAC AGAGTACTCT GTCAATGGAT 
GCCATCCATG CCAACTCAAT GGAACTTATT GCTGGAAGTG TTGACACGAC AGCAATCTCC 
TTGGTAATGA CCCTTTTTGA GCTGGCTCGG AACCCAGATG TTCAGCAGGC CCTGCGGCAG 
GAGAGCCTGG CAGCTGAGGC CAGCATCGCT GCTAATCCCC AGAAGGCCAT GTCAGACTTG 
CCCTTGCTGC GGGCTGCCCT TAAAGAGACC TTGAGGCTCT ACCCCATTGG TAGCTCTTTG 
GAGAGAATCG TAGACTCAGA CCTGGTGCTT CAGAACTATC ATGTCCCTGC TGGGACGTTG 
GTCATAATTT ATCTGTACTC CATGGGCCGA AACCCTGCAG TGTTCCCAAG ACCTGAGCGC 
TACATGCCTC AGCGCTGGCT GGAGAGGAAA AGGAGTTTCC AGCATCTGGC CTTCGGCTTT 
GGGGTGCGCC AGTGCCTGGG GCGGCGCCTG GCAGAGGTGG AGGTGTTGCT CCTGCTTCAC 
CATATGCTGA AAATCTTCCA AGTCGAGACA CTGAGGCAAG AGGATGTGCA GATGGCCTAT 
CGCTTTGTTT TGATGCCCAA CCCTAGACTC GTCCTCACTA TCCGGCCTGT GAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp11b3 ( XM_008765572.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763794.1 Rattus norvegicus cytochrome P450, family 11, subfamily b, polypeptide 3 (Cyp11b3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa47653
Clone ID Related Accession (Same CDS sequence)	XM_008765572.2
Accession Version	XM_008765572.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome P450, family 11, subfamily b, polypeptide 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765572.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAATGG CTCTCAGGGT GACAGCAGAT GTGTGGGCAA GACCCTGGCA GTGCCTGCAC 
AGGACGAGGG CACTGGGCAG TACGGCAACA CAGGCCCCCA AGACACTGAA GCCCTTTGAA 
GCCATACCAC AATACTCCAG GAACAAGTGG CTGAAGATGA TACAGATCCT GAGGGAGCAG 
GGCCAAGAGA ACCTACACCT GGAGATGCAC CAGGCCTTCC AGGAACTAGG GCCCATTTTC 
AGGCACAGTG CAGGGGGAGC ACAGATTGTG TCTGTGATGC TGCCTGAGGA CGCTGAGAAG 
CTGCACCAGG TGGAGAGTAT CCTCCCGCGT CGGATGACGC TGGAGTCGTG GGTGGCCCAC 
AGAGAACTCC GTGGCCTGAG ACGTGGTGTG TTCTTGCTAA ATGGGGCAGA CTGGCGCTTC 
AACCGACTGC AGCTGAATCC AAATATGCTG TCACCAAAAG CCGTTCAATC TTTTGTCCCC 
TTTGTGGATG TGGTAGCAAG GGACTTTGTG GAAAACCTGA AGAAGAGAAT GCTGGAGAAT 
GTTCATGGAA GCATGTCTAT GGACATTCAG TCCAATGTGT TCAACTATAC CATGGAAGCC 
AGCCATTTTG TTATTTCCGG AGAGCGACTG GGCCTCACAG GCCATGACCT GAAACCTGAG 
AGCCTGAAGT TCATTCATGC TCTGCACTCA ATGTTCAAGT CCACCACACA GCTCATGTTC 
TTACCCAAGA ACTTGACTCG TTGGACAAGC ACCCAGGTGT GGAAAGGACA CTTTGAGTCC 
TGGGATATCA TCTCTGAGTA TGTCACAAAA TGTATCAAGA ATGTGTATCG CGAACTGGCA 
GAGGGTCGCC AACAGTCCTG GAGTGTCATA TCCGAGATGG TAGCACAGAG TACTCTGTCA 
ATGGATGCCA TCCATGCCAA CTCAATGGAA CTTATTGCTG GAAGTGTTGA CACGACAGCA 
ATCTCCTTGG TAATGACCCT TTTTGAGCTG GCTCGGAACC CAGATGTTCA GCAGGCCCTG 
CGGCAGGAGA GCCTGGCAGC TGAGGCCAGC ATCGCTGCTA ATCCCCAGAA GGCCATGTCA 
GACTTGCCCT TGCTGCGGGC TGCCCTTAAA GAGACCTTGA GGCTCTACCC CATTGGTAGC 
TCTTTGGAGA GAATCGTAGA CTCAGACCTG GTGCTTCAGA ACTATCATGT CCCTGCTGGG 
ATGCTGAAAA TCTTCCAAGT CGAGACACTG AGGCAAGAGG ATGTGCAGAT GGCCTATCGC 
TTTGTTTTGA TGCCCAACCC TAGACTCGTC CTCACTATCC GGCCTGTGAG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763794.1
CDS	68..1381
Translation	MAMALRVTADVWARPWQCLHRTRALGSTATQAPKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPRRMTLESWVAHRELRGLRRGVFLLNGADWRFNRLQLNPNMLSPKAVQSFVPFVDVVARDFVENLKKRMLENVHGSMSMDIQSNVFNYTMEASHFVISGERLGLTGHDLKPESLKFIHALHSMFKSTTQLMFLPKNLTRWTSTQVWKGHFESWDIISEYVTKCIKNVYRELAEGRQQSWSVISEMVAQSTLSMDAIHANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPIGSSLERIVDSDLVLQNYHVPAGMLKIFQVETLRQEDVQMAYRFVLMPNPRLVLTIRPVS

Target ORF information:

RefSeq Version	XM_008765572.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 11, subfamily b, polypeptide 3 (Cyp11b3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765572.2

ORF Insert Sequence:

ATGGCAATGG CTCTCAGGGT GACAGCAGAT GTGTGGGCAA GACCCTGGCA GTGCCTGCAC 
AGGACGAGGG CACTGGGCAG TACGGCAACA CAGGCCCCCA AGACACTGAA GCCCTTTGAA 
GCCATACCAC AATACTCCAG GAACAAGTGG CTGAAGATGA TACAGATCCT GAGGGAGCAG 
GGCCAAGAGA ACCTACACCT GGAGATGCAC CAGGCCTTCC AGGAACTAGG GCCCATTTTC 
AGGCACAGTG CAGGGGGAGC ACAGATTGTG TCTGTGATGC TGCCTGAGGA CGCTGAGAAG 
CTGCACCAGG TGGAGAGTAT CCTCCCGCGT CGGATGACGC TGGAGTCGTG GGTGGCCCAC 
AGAGAACTCC GTGGCCTGAG ACGTGGTGTG TTCTTGCTAA ATGGGGCAGA CTGGCGCTTC 
AACCGACTGC AGCTGAATCC AAATATGCTG TCACCAAAAG CCGTTCAATC TTTTGTCCCC 
TTTGTGGATG TGGTAGCAAG GGACTTTGTG GAAAACCTGA AGAAGAGAAT GCTGGAGAAT 
GTTCATGGAA GCATGTCTAT GGACATTCAG TCCAATGTGT TCAACTATAC CATGGAAGCC 
AGCCATTTTG TTATTTCCGG AGAGCGACTG GGCCTCACAG GCCATGACCT GAAACCTGAG 
AGCCTGAAGT TCATTCATGC TCTGCACTCA ATGTTCAAGT CCACCACACA GCTCATGTTC 
TTACCCAAGA ACTTGACTCG TTGGACAAGC ACCCAGGTGT GGAAAGGACA CTTTGAGTCC 
TGGGATATCA TCTCTGAGTA TGTCACAAAA TGTATCAAGA ATGTGTATCG CGAACTGGCA 
GAGGGTCGCC AACAGTCCTG GAGTGTCATA TCCGAGATGG TAGCACAGAG TACTCTGTCA 
ATGGATGCCA TCCATGCCAA CTCAATGGAA CTTATTGCTG GAAGTGTTGA CACGACAGCA 
ATCTCCTTGG TAATGACCCT TTTTGAGCTG GCTCGGAACC CAGATGTTCA GCAGGCCCTG 
CGGCAGGAGA GCCTGGCAGC TGAGGCCAGC ATCGCTGCTA ATCCCCAGAA GGCCATGTCA 
GACTTGCCCT TGCTGCGGGC TGCCCTTAAA GAGACCTTGA GGCTCTACCC CATTGGTAGC 
TCTTTGGAGA GAATCGTAGA CTCAGACCTG GTGCTTCAGA ACTATCATGT CCCTGCTGGG 
ATGCTGAAAA TCTTCCAAGT CGAGACACTG AGGCAAGAGG ATGTGCAGAT GGCCTATCGC 
TTTGTTTTGA TGCCCAACCC TAGACTCGTC CTCACTATCC GGCCTGTGAG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural insights into aldosterone synthase substrate specificity and targeted inhibition.
Molecular endocrinology (Baltimore, Md.)27(2)315-24(2013 Feb)
Strushkevich N,Gilep AA,Shen L,Arrowsmith CH,Edwards AM,Usanov SA,Park HW

Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor.
Endocrinology150(7)3110-7(2009 Jul)
Somekawa S,Imagawa K,Naya N,Takemoto Y,Onoue K,Okayama S,Takeda Y,Kawata H,Horii M,Nakajima T,Uemura S,Mochizuki N,Saito Y

A missense mutation (GGC[435Gly]-->AGC[Ser]) in exon 8 of the CYP11B2 gene inherited in Japanese patients with congenital hypoaldosteronism.
Hormone research60(5)255-60(2003)
Kuribayashi I,Kuge H,Santa RJ,Mutlaq AZ,Yamasaki N,Furuno T,Takahashi A,Chida S,Nakamura T,Endo F,Doi Y,Onishi S,Shizuta Y

An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy.
Cardiovascular research54(3)584-9(2002 Jun)
Tiago AD,Badenhorst D,Skudicky D,Woodiwiss AJ,Candy GP,Brooksbank R,Sliwa K,Sareli P,Norton GR

Genetic variation in aldosterone synthase predicts plasma glucose levels.
Proceedings of the National Academy of Sciences of the United States of America98(23)13219-24(2001 Nov)
Ranade K,Wu KD,Risch N,Olivier M,Pei D,Hsiao CF,Chuang LM,Ho LT,Jorgenson E,Pesich R,Chen YD,Dzau V,Lin A,Olshen RA,Curb D,Cox DR,Botstein D

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Cyp11b3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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