Pip5k1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pip5k1b
Entrez Gene ID	309419
Full Name	phosphatidylinositol-4-phosphate 5-kinase type 1 beta
Synonyms	Pip5k1a
General protein information	Preferred Names phosphatidylinositol-4-phosphate 5-kinase type 1 beta Names phosphatidylinositol 4-phosphate 5-kinase type-1 beta PIP5K1-beta PIP5KIalpha PIP5KIbeta phosphatidylinositol 4-phosphate 5-kinase type I alpha phosphatidylinositol 4-phosphate 5-kinase type I beta phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha ptdIns(4)P-5-kinase 1 beta ptdIns(4)P-5-kinase beta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q51

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012743.1	NP_001012761.1	phosphatidylinositol 4-phosphate 5-kinase type-1 beta
XM_017589273.1	XP_017444762.1	phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pip5k1b	NP_032872.1
Rattus norvegicus (Norway rat)	Pip5k1b	NP_001012761.1
Neurospora crassa	NCU02295	XP_959939.1
Bos taurus (cattle)	PIP5K1B	XP_005210080.1
Gallus gallus (chicken)	PIP5K1B	NP_001026593.1
Homo sapiens (human)	PIP5K1B	NP_003549.1
Pan troglodytes (chimpanzee)	PIP5K1B	XP_001137127.1
	PIP5K1B	XP_001088891.2
Danio rerio (zebrafish)	pip5k1bb	NP_001004579.1
Oryza sativa (rice)	Os03g0262000	NP_001049624.1
Xenopus tropicalis (tropical clawed frog)	pip5k1b	XP_002935644.2
Canis lupus familiaris (dog)	PIP5K1B	XP_533533.3
Magnaporthe oryzae (rice blast fungus)	MGG_06572	XP_003716964.1

Gene Ontology
Bibliography

Related articles in PubMed

Phosphatidylinositol 4-phosphate 5-kinase ? negatively regulates nerve growth factor-induced neurite outgrowth in PC12 cells.
Liu T, Lee SY
Experimental & molecular medicine45e16(2013 Mar)

Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.
Volpicelli-Daley LA, Lucast L, Gong LW, Liu L, Sasaki J, Sasaki T, Abrams CS, Kanaho Y, De Camilli P
The Journal of biological chemistry285(37)28708-14(2010 Sep)

An isoform-specific PDZ-binding motif targets type I PIP5 kinase beta to the uropod and controls polarization of neutrophil-like HL60 cells.
Ma?es S, Fuentes G, Peregil RM, Rojas AM, Lacalle RA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology24(9)3381-92(2010 Sep)

Phosphatidylinositol 4-phosphate 5-kinase alpha is induced in ganglioside-stimulated brain astrocytes and contributes to inflammatory responses.
Lee SY, Kim B, Yoon S, Kim YJ, Liu T, Woo JH, Chwae YJ, Joe EH, Jou I
Experimental & molecular medicine42(9)662-73(2010 Sep)

The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells.
Vasudevan L, Jeromin A, Volpicelli-Daley L, De Camilli P, Holowka D, Baird B
Journal of cell science122(Pt 14)2567-74(2009 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PIP5Kalpha acts as a negative regulator of nerve growth factor-induced neurite outgrowth by inhibiting PI3K/Akt signaling pathway in PC12 cells.
Title: Phosphatidylinositol 4-phosphate 5-kinase ? negatively regulates nerve growth factor-induced neurite outgrowth in PC12 cells.

Ganglioside treatment of primary astrocytes enhances PIP5Kalpha expression. PIP5Kalpha knockdown attenuates ganglioside-induced inflammatory responses.
Title: Phosphatidylinositol 4-phosphate 5-kinase alpha is induced in ganglioside-stimulated brain astrocytes and contributes to inflammatory responses.

The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells.
Title: The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells.

The following Pip5k1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pip5k1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03014	NM_001012743.1 Latest version!	Rattus norvegicus phosphatidylinositol-4-phosphate 5-kinase type 1 beta (Pip5k1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa03014	XM_017589273.1 Latest version!	Rattus norvegicus phosphatidylinositol-4-phosphate 5-kinase type 1 beta (Pip5k1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pip5k1b ( NM_001012743.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012761.1 Rattus norvegicus phosphatidylinositol-4-phosphate 5-kinase type 1 beta (Pip5k1b), mRNA.

Price & Availability↑

CloneID	ORa03014
Clone ID Related Accession (Same CDS sequence)	NM_001012743.1 , XM_017589273.1
Accession Version	NM_001012743.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 4-phosphate 5-kinase type-1 beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC090349.1. On Apr 20, 2005 this sequence version replaced XM_219913.3. ##Evidence-Data-START## Transcript exon combination :: BC090349.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCGTCAA CTGCTGAAAA TGGAGACGCC GTACCTGGAA AACAAAACGA AGAAAAAACC 
TACAAAAAGA CTGCATCATC AGCTATTAAA GGTGCCATTC AGCTGGGAAT AGGATACACA 
GTGGGTAATC TCACTTCCAA GCCAGAACGC GATGTCCTCA TGCAAGACTT TTATGTGGTG 
GAAAGTGTAT TCCTCCCCAG TGAAGGGAGC AATCTGACCC CAGCACATCA CTACCCAGAC 
TTCAGGTTTA AGACATACGC CCCGCTGGCT TTCCGCTACT TCCGAGAACT CTTTGGTATC 
AAGCCCGACG ATTACTTGTA CTCCATCTGC AGTGAACCGC TGATAGAACT GTCCAATCCT 
GGAGCCAGTG GATCCTTGTT TTTCTTGACC AGCGATGATG AATTTATTAT CAAAACTGTT 
CAGCATAAGG AAGCCGAGTT CCTGCAGAAG CTGCTGCCAG GCTATTACAT GAATCTAAAC 
CAGAATCCAA GGACTCTCCT GCCGAAATTC TATGGTCTGT ATTGCATGCA GTCAGGAGGC 
ATCAACATCC GCATCGTGGT GATGAACAAC GTGCTGCCGC GTGCCATGAG GATGCACTTG 
ACCTATGACC TGAAAGGCTC CACGTACAAA CGAAGGGCGT CCCGAAAAGA GAGGGAGAAA 
CCCAACCCCA CGTTTAAGGA CCTGGACTTC CTGCAGGACA TGCATGAGGG GCTGTATTTC 
GATACAGAAA CATACAATGC CCTTATGAAG ACACTACAGA GAGACTGCCG GGTGCTGGAA 
AGCTTCAAGA TCATGGACTA CAGCCTTTTG CTGGGTATCC ACATCTTGGA CCATTCCCTC 
AAAGACAAAG AAGAGGAGCC CCTCCAAAAT GCACCCGACG CAAAGCGGCC GGGGATGCAG 
AAAGTCCTCT ACTCCACAGC CATGGAGTCC ATCCAGGGTC CAGGCAAGTC CGCAGATGGG 
ATCATTGCAG AGAACCCAGA CACAATGGGA GGCATTCCAG CTAAAAGCCA TAAGGGAGAA 
AAGCTGCTTC TATTCATGGG CATTATTGAT ATTCTCCAAT CATATAGGTT AATGAAGAAG 
TTAGAACACT CCTGGAAAGC TCTTGTGTAT GATGGGGACA CCGTTTCAGT TCATAGACCA 
AGTTTTTATG CAGATAGATT TTTAAAGTTT ATGAATTCCA GAGTTTTCAA GAAAATTCAA 
GCTCTGAAGG CCTCACCTTC TAAGAAACGG TGCAACTCCA TCGCTGCACT GAAGGCAACC 
TCCCAGGAGA TTCTGTCCTC CATCAGCCAA GAATGGAAGG ATGAGAAGCA GGATCTGTTA 
ACCGAAGGGC AGAGTTTCAG CAGCCTGGAT GAAGAAGCCC TGGGATCCCG ACACAGGCCT 
GACCTGGTGC CCAGCACGCC GTCATTATTT GAAGCTGCTT CCTTAGCAAC CACAATATCA 
TCTTCTTCCT TATATGTCGG TGAGCACTAT CCACACGACA GGACTACGCT TTACTCAAAC 
AGCAAAGGGT TACCTTCCAG TTCAACCTTC ACCTTGGAAG AGGGGACCAT CTACCTGACT 
GCTGAGCCAA ACGCCCTGGA AACGCAGGAT GACGCCTCCG TGCTGGATGT CTATTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012761.1
CDS	528..2147
Translation	MSSTAENGDAVPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEEEPLQNAPDAKRPGMQKVLYSTAMESIQGPGKSADGIIAENPDTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKATSQEILSSISQEWKDEKQDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVGEHYPHDRTTLYSNSKGLPSSSTFTLEEGTIYLTAEPNALETQDDASVLDVYL

Target ORF information:

RefSeq Version	NM_001012743.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphatidylinositol-4-phosphate 5-kinase type 1 beta (Pip5k1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012743.1

ORF Insert Sequence:

ATGTCGTCAA CTGCTGAAAA TGGAGACGCC GTACCTGGAA AACAAAACGA AGAAAAAACC 
TACAAAAAGA CTGCATCATC AGCTATTAAA GGTGCCATTC AGCTGGGAAT AGGATACACA 
GTGGGTAATC TCACTTCCAA GCCAGAACGC GATGTCCTCA TGCAAGACTT TTATGTGGTG 
GAAAGTGTAT TCCTCCCCAG TGAAGGGAGC AATCTGACCC CAGCACATCA CTACCCAGAC 
TTCAGGTTTA AGACATACGC CCCGCTGGCT TTCCGCTACT TCCGAGAACT CTTTGGTATC 
AAGCCCGACG ATTACTTGTA CTCCATCTGC AGTGAACCGC TGATAGAACT GTCCAATCCT 
GGAGCCAGTG GATCCTTGTT TTTCTTGACC AGCGATGATG AATTTATTAT CAAAACTGTT 
CAGCATAAGG AAGCCGAGTT CCTGCAGAAG CTGCTGCCAG GCTATTACAT GAATCTAAAC 
CAGAATCCAA GGACTCTCCT GCCGAAATTC TATGGTCTGT ATTGCATGCA GTCAGGAGGC 
ATCAACATCC GCATCGTGGT GATGAACAAC GTGCTGCCGC GTGCCATGAG GATGCACTTG 
ACCTATGACC TGAAAGGCTC CACGTACAAA CGAAGGGCGT CCCGAAAAGA GAGGGAGAAA 
CCCAACCCCA CGTTTAAGGA CCTGGACTTC CTGCAGGACA TGCATGAGGG GCTGTATTTC 
GATACAGAAA CATACAATGC CCTTATGAAG ACACTACAGA GAGACTGCCG GGTGCTGGAA 
AGCTTCAAGA TCATGGACTA CAGCCTTTTG CTGGGTATCC ACATCTTGGA CCATTCCCTC 
AAAGACAAAG AAGAGGAGCC CCTCCAAAAT GCACCCGACG CAAAGCGGCC GGGGATGCAG 
AAAGTCCTCT ACTCCACAGC CATGGAGTCC ATCCAGGGTC CAGGCAAGTC CGCAGATGGG 
ATCATTGCAG AGAACCCAGA CACAATGGGA GGCATTCCAG CTAAAAGCCA TAAGGGAGAA 
AAGCTGCTTC TATTCATGGG CATTATTGAT ATTCTCCAAT CATATAGGTT AATGAAGAAG 
TTAGAACACT CCTGGAAAGC TCTTGTGTAT GATGGGGACA CCGTTTCAGT TCATAGACCA 
AGTTTTTATG CAGATAGATT TTTAAAGTTT ATGAATTCCA GAGTTTTCAA GAAAATTCAA 
GCTCTGAAGG CCTCACCTTC TAAGAAACGG TGCAACTCCA TCGCTGCACT GAAGGCAACC 
TCCCAGGAGA TTCTGTCCTC CATCAGCCAA GAATGGAAGG ATGAGAAGCA GGATCTGTTA 
ACCGAAGGGC AGAGTTTCAG CAGCCTGGAT GAAGAAGCCC TGGGATCCCG ACACAGGCCT 
GACCTGGTGC CCAGCACGCC GTCATTATTT GAAGCTGCTT CCTTAGCAAC CACAATATCA 
TCTTCTTCCT TATATGTCGG TGAGCACTAT CCACACGACA GGACTACGCT TTACTCAAAC 
AGCAAAGGGT TACCTTCCAG TTCAACCTTC ACCTTGGAAG AGGGGACCAT CTACCTGACT 
GCTGAGCCAA ACGCCCTGGA AACGCAGGAT GACGCCTCCG TGCTGGATGT CTATTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pip5k1b ( XM_017589273.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444762.1 Rattus norvegicus phosphatidylinositol-4-phosphate 5-kinase type 1 beta (Pip5k1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa03014
Clone ID Related Accession (Same CDS sequence)	NM_001012743.1 , XM_017589273.1
Accession Version	XM_017589273.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGTCAA CTGCTGAAAA TGGAGACGCC GTACCTGGAA AACAAAACGA AGAAAAAACC 
TACAAAAAGA CTGCATCATC AGCTATTAAA GGTGCCATTC AGCTGGGAAT AGGATACACA 
GTGGGTAATC TCACTTCCAA GCCAGAACGC GATGTCCTCA TGCAAGACTT TTATGTGGTG 
GAAAGTGTAT TCCTCCCCAG TGAAGGGAGC AATCTGACCC CAGCACATCA CTACCCAGAC 
TTCAGGTTTA AGACATACGC CCCGCTGGCT TTCCGCTACT TCCGAGAACT CTTTGGTATC 
AAGCCCGACG ATTACTTGTA CTCCATCTGC AGTGAACCGC TGATAGAACT GTCCAATCCT 
GGAGCCAGTG GATCCTTGTT TTTCTTGACC AGCGATGATG AATTTATTAT CAAAACTGTT 
CAGCATAAGG AAGCCGAGTT CCTGCAGAAG CTGCTGCCAG GCTATTACAT GAATCTAAAC 
CAGAATCCAA GGACTCTCCT GCCGAAATTC TATGGTCTGT ATTGCATGCA GTCAGGAGGC 
ATCAACATCC GCATCGTGGT GATGAACAAC GTGCTGCCGC GTGCCATGAG GATGCACTTG 
ACCTATGACC TGAAAGGCTC CACGTACAAA CGAAGGGCGT CCCGAAAAGA GAGGGAGAAA 
CCCAACCCCA CGTTTAAGGA CCTGGACTTC CTGCAGGACA TGCATGAGGG GCTGTATTTC 
GATACAGAAA CATACAATGC CCTTATGAAG ACACTACAGA GAGACTGCCG GGTGCTGGAA 
AGCTTCAAGA TCATGGACTA CAGCCTTTTG CTGGGTATCC ACATCTTGGA CCATTCCCTC 
AAAGACAAAG AAGAGGAGCC CCTCCAAAAT GCACCCGACG CAAAGCGGCC GGGGATGCAG 
AAAGTCCTCT ACTCCACAGC CATGGAGTCC ATCCAGGGTC CAGGCAAGTC CGCAGATGGG 
ATCATTGCAG AGAACCCAGA CACAATGGGA GGCATTCCAG CTAAAAGCCA TAAGGGAGAA 
AAGCTGCTTC TATTCATGGG CATTATTGAT ATTCTCCAAT CATATAGGTT AATGAAGAAG 
TTAGAACACT CCTGGAAAGC TCTTGTGTAT GATGGGGACA CCGTTTCAGT TCATAGACCA 
AGTTTTTATG CAGATAGATT TTTAAAGTTT ATGAATTCCA GAGTTTTCAA GAAAATTCAA 
GCTCTGAAGG CCTCACCTTC TAAGAAACGG TGCAACTCCA TCGCTGCACT GAAGGCAACC 
TCCCAGGAGA TTCTGTCCTC CATCAGCCAA GAATGGAAGG ATGAGAAGCA GGATCTGTTA 
ACCGAAGGGC AGAGTTTCAG CAGCCTGGAT GAAGAAGCCC TGGGATCCCG ACACAGGCCT 
GACCTGGTGC CCAGCACGCC GTCATTATTT GAAGCTGCTT CCTTAGCAAC CACAATATCA 
TCTTCTTCCT TATATGTCGG TGAGCACTAT CCACACGACA GGACTACGCT TTACTCAAAC 
AGCAAAGGGT TACCTTCCAG TTCAACCTTC ACCTTGGAAG AGGGGACCAT CTACCTGACT 
GCTGAGCCAA ACGCCCTGGA AACGCAGGAT GACGCCTCCG TGCTGGATGT CTATTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444762.1
CDS	1389..3008
Translation	MSSTAENGDAVPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEEEPLQNAPDAKRPGMQKVLYSTAMESIQGPGKSADGIIAENPDTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKATSQEILSSISQEWKDEKQDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVGEHYPHDRTTLYSNSKGLPSSSTFTLEEGTIYLTAEPNALETQDDASVLDVYL

Target ORF information:

RefSeq Version	XM_017589273.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphatidylinositol-4-phosphate 5-kinase type 1 beta (Pip5k1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589273.1

ORF Insert Sequence:

ATGTCGTCAA CTGCTGAAAA TGGAGACGCC GTACCTGGAA AACAAAACGA AGAAAAAACC 
TACAAAAAGA CTGCATCATC AGCTATTAAA GGTGCCATTC AGCTGGGAAT AGGATACACA 
GTGGGTAATC TCACTTCCAA GCCAGAACGC GATGTCCTCA TGCAAGACTT TTATGTGGTG 
GAAAGTGTAT TCCTCCCCAG TGAAGGGAGC AATCTGACCC CAGCACATCA CTACCCAGAC 
TTCAGGTTTA AGACATACGC CCCGCTGGCT TTCCGCTACT TCCGAGAACT CTTTGGTATC 
AAGCCCGACG ATTACTTGTA CTCCATCTGC AGTGAACCGC TGATAGAACT GTCCAATCCT 
GGAGCCAGTG GATCCTTGTT TTTCTTGACC AGCGATGATG AATTTATTAT CAAAACTGTT 
CAGCATAAGG AAGCCGAGTT CCTGCAGAAG CTGCTGCCAG GCTATTACAT GAATCTAAAC 
CAGAATCCAA GGACTCTCCT GCCGAAATTC TATGGTCTGT ATTGCATGCA GTCAGGAGGC 
ATCAACATCC GCATCGTGGT GATGAACAAC GTGCTGCCGC GTGCCATGAG GATGCACTTG 
ACCTATGACC TGAAAGGCTC CACGTACAAA CGAAGGGCGT CCCGAAAAGA GAGGGAGAAA 
CCCAACCCCA CGTTTAAGGA CCTGGACTTC CTGCAGGACA TGCATGAGGG GCTGTATTTC 
GATACAGAAA CATACAATGC CCTTATGAAG ACACTACAGA GAGACTGCCG GGTGCTGGAA 
AGCTTCAAGA TCATGGACTA CAGCCTTTTG CTGGGTATCC ACATCTTGGA CCATTCCCTC 
AAAGACAAAG AAGAGGAGCC CCTCCAAAAT GCACCCGACG CAAAGCGGCC GGGGATGCAG 
AAAGTCCTCT ACTCCACAGC CATGGAGTCC ATCCAGGGTC CAGGCAAGTC CGCAGATGGG 
ATCATTGCAG AGAACCCAGA CACAATGGGA GGCATTCCAG CTAAAAGCCA TAAGGGAGAA 
AAGCTGCTTC TATTCATGGG CATTATTGAT ATTCTCCAAT CATATAGGTT AATGAAGAAG 
TTAGAACACT CCTGGAAAGC TCTTGTGTAT GATGGGGACA CCGTTTCAGT TCATAGACCA 
AGTTTTTATG CAGATAGATT TTTAAAGTTT ATGAATTCCA GAGTTTTCAA GAAAATTCAA 
GCTCTGAAGG CCTCACCTTC TAAGAAACGG TGCAACTCCA TCGCTGCACT GAAGGCAACC 
TCCCAGGAGA TTCTGTCCTC CATCAGCCAA GAATGGAAGG ATGAGAAGCA GGATCTGTTA 
ACCGAAGGGC AGAGTTTCAG CAGCCTGGAT GAAGAAGCCC TGGGATCCCG ACACAGGCCT 
GACCTGGTGC CCAGCACGCC GTCATTATTT GAAGCTGCTT CCTTAGCAAC CACAATATCA 
TCTTCTTCCT TATATGTCGG TGAGCACTAT CCACACGACA GGACTACGCT TTACTCAAAC 
AGCAAAGGGT TACCTTCCAG TTCAACCTTC ACCTTGGAAG AGGGGACCAT CTACCTGACT 
GCTGAGCCAA ACGCCCTGGA AACGCAGGAT GACGCCTCCG TGCTGGATGT CTATTTATAA