Rgma cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rgma
Entrez Gene ID	308739
Full Name	repulsive guidance molecule family member A
General protein information	Preferred Names repulsive guidance molecule family member A Names repulsive guidance molecule A RGM domain family, member A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q31

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107524.1	NP_001100994.1	repulsive guidance molecule A
XM_008759521.2	XP_008757743.1	repulsive guidance molecule A isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	RGMA	NP_064596.2
Bos taurus (cattle)	RGMA	XP_002696554.1
Gallus gallus (chicken)	RGMA	NP_989868.1
Canis lupus familiaris (dog)	RGMA	XP_005618378.1
Pan troglodytes (chimpanzee)	RGMA	XP_510608.3
Rattus norvegicus (Norway rat)	Rgma	NP_001100994.1
Danio rerio (zebrafish)	rgma	NP_001038476.1
Xenopus tropicalis (tropical clawed frog)	rgma	NP_989056.1
	RGMA	XP_002804993.1
Mus musculus (house mouse)	Rgma	NP_808408.2

Gene Ontology
Bibliography

Related articles in PubMed

Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.
Wang Y, Zhang R, Xing X, Guo J, Xie F, Zhang G, Qin X
Neuroscience letters662318-323(2018 Jan)

Lentiviral Vector-Induced Overexpression of RGMa in the Hippocampus Suppresses Seizures and Mossy Fiber Sprouting.
Chen L, Gao B, Fang M, Li J, Mi X, Xu X, Wang W, Gu J, Tang B, Zhang Y, Wang Z, Zhan A, Chen G, Wang X
Molecular neurobiology54(2)1379-1391(2017 Mar)

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.
van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ
Developmental cell35(5)537-52(2015 Dec)

Potential roles of the RGMa-FAK-Ras pathway in hippocampal mossy fiber sprouting in the pentylenetetrazole kindling model.
Song MY, Tian FF, Wang YZ, Huang X, Guo JL, Ding DX
Molecular medicine reports11(3)1738-44(2015 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the RGMaFAKRas pathway may be involved in MFS and the development of temporal lobe epilepsy.
Title: Potential roles of the RGMa-FAK-Ras pathway in hippocampal mossy fiber sprouting in the pentylenetetrazole kindling model.

this study suggests that RGMa regulates the proper axonal branching of hippocampal mossy fibers
Title: Repulsive guidance molecule a regulates hippocampal mossy fiber branching in vitro.

RGMa inhibits axon growth by phosphorylating CRMP-2 via both Rho-kinase and GSK-3beta signaling pathways.
Title: CRMP-2 is involved in axon growth inhibition induced by RGMa in vitro and in vivo.

Minocycline-induced down-regulation of RGMa expression was associated with enhanced axonal regeneration after cerebral ischemia-reperfusion.
Title: Minocycline promotes axonal regeneration through suppression of RGMa in rat MCAO/reperfusion model.

we concluded that RGMa could be another key molecule and might inhibit axonal regeneration during cerebral ischemia/reperfusion injury
Title: Fastigial nucleus electrostimulation reduces the expression of repulsive guidance molecule, improves axonal growth following focal cerebral ischemia.

The following Rgma gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rgma cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12167	NM_001107524.1 Latest version!	Rattus norvegicus repulsive guidance molecule BMP co-receptor a (Rgma), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
ORa46646	XM_008759521.2 Latest version!	Rattus norvegicus repulsive guidance molecule family member A (Rgma), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rgma ( NM_001107524.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100994.1 Rattus norvegicus repulsive guidance molecule BMP co-receptor a (Rgma), mRNA.

Price & Availability↑

CloneID	ORa12167
Clone ID Related Accession (Same CDS sequence)	NM_001107524.1
Accession Version	NM_001107524.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Rattus norvegicus(Norway rat)
Product	repulsive guidance molecule A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473980.1. On or before Oct 4, 2007 this sequence version replaced XM_218791.4, XM_001062354.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCCGC CAAGGGAGAG GCTAGTGGTA ACAGGCCGAG CTGGATGGAT GGGTATGGGG 
AGAGGGGCAG GACGTTCAGC CCTGGGATTG TGGCCGACCC TCGCCTTCCT TCTCTGCAGC 
TTTCCCGCAG CTATCTCTCC CTGCAAGATC CTCAAGTGCA ACTCTGAGTT CTGGAGCGCC 
ACGTCGTCAG GCAGCCACGC CCCTGCCTCT GACGACGTGC CCGAGTTCTG TGCTGCCCTG 
CGCACCTACG CCCTGTGCAC GCGACGGACA GCCCGCACCT GCCGGGGCGA CCTGGCTTAC 
CACTCGGCTG TCCATGGCAT AGAGGACCTC ATGAGCCAGC ACAACTGCTC CAAGGATGGC 
CCCACCTCAC AGCCTCGAGT GCGCACGCTC CCGCCAGCTG GGGACAGCCA GGAGCGCTCA 
GATAGCCCCG AGATCTGCCA CTATGAGAAG AGTTTCCACA AGCACTCAGC TGCCCCCAAC 
TACACTCACT GCGGCCTCTT TGGGGACCCA CACCTCAGGA CTTTCACAGA CCACTTCCAG 
ACATGTAAGG TGCAAGGCGC TTGGCCTCTC ATCGACAATA ATTACCTGAA CGTGCAGGTC 
ACCAATACAC CTGTGCTGCC CGGCTCTGCC GCCACTGCCA CCAGCAAGCT CACCATCATC 
TTCAAGAACT TCCAAGAGTG TGTGGACCAG AAAGTATACC AAGCCGAGAT GGACGAGCTT 
CCGTCCGCCT TTGCCGATGG CTCCAAAAAC GGTGGAGATA AACACGGAGC CAACAGCCTG 
AAGATCACAG AGAAGGTGTC AGGCCAGCAC GTGGAGATCC AGGCCAAGTA CATCGGCACC 
ACCATCGTGG TGAGACAGGT GGGCCGCTAC CTGACCTTCG CCGTCCGGAT GCCCGAGGAG 
GTAGTCAACG CCGTGGAGGA CCGTGACAGC CAAGGCCTCT ACCTCTGCCT GCGGGGCTGC 
CCGCTCAACC AGCAGATCGA CTTCCAGGCT TTCCGTGCCA ACGCCGAGAG CCCTCGCAGG 
CCAGCAGCTG CCAGCCCCTC TCCTGTGGTC CCCGAGACAT TTCCGTACGA GACAGCTGTG 
GCCAAGTGCA AAGAGAAGCT GCCTGTAGAA GACTTGTACT ACCAGGCCTG TGTCTTCGAC 
CTCCTCACGA CTGGCGACGT GAACTTCACG CTGGCCGCCT ACTATGCTTT GGAGGATGGC 
AAGATGCTCC ACTCCAACAA GGACAAGCTA CACCTGTTTG AAAGGACTCG GGAGCTGCCT 
GGCGCTGTGG CCGCTGCAGC ATTTCCCTTG GCCCCCGAGA TGCTCCCGGG CACCGTCACA 
CTTCTGGTCC TGCTGCCTCT GTTCTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100994.1
CDS	353..1702
Translation	MQPPRERLVVTGRAGWMGMGRGAGRSALGLWPTLAFLLCSFPAAISPCKILKCNSEFWSATSSGSHAPASDDVPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRVRTLPPAGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDHFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPSAFADGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQAFRANAESPRRPAAASPSPVVPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDGKMLHSNKDKLHLFERTRELPGAVAAAAFPLAPEMLPGTVTLLVLLPLFW

Target ORF information:

RefSeq Version	NM_001107524.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus repulsive guidance molecule BMP co-receptor a (Rgma), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107524.1

ORF Insert Sequence:

ATGCAGCCGC CAAGGGAGAG GCTAGTGGTA ACAGGCCGAG CTGGATGGAT GGGTATGGGG 
AGAGGGGCAG GACGTTCAGC CCTGGGATTG TGGCCGACCC TCGCCTTCCT TCTCTGCAGC 
TTTCCCGCAG CTATCTCTCC CTGCAAGATC CTCAAGTGCA ACTCTGAGTT CTGGAGCGCC 
ACGTCGTCAG GCAGCCACGC CCCTGCCTCT GACGACGTGC CCGAGTTCTG TGCTGCCCTG 
CGCACCTACG CCCTGTGCAC GCGACGGACA GCCCGCACCT GCCGGGGCGA CCTGGCTTAC 
CACTCGGCTG TCCATGGCAT AGAGGACCTC ATGAGCCAGC ACAACTGCTC CAAGGATGGC 
CCCACCTCAC AGCCTCGAGT GCGCACGCTC CCGCCAGCTG GGGACAGCCA GGAGCGCTCA 
GATAGCCCCG AGATCTGCCA CTATGAGAAG AGTTTCCACA AGCACTCAGC TGCCCCCAAC 
TACACTCACT GCGGCCTCTT TGGGGACCCA CACCTCAGGA CTTTCACAGA CCACTTCCAG 
ACATGTAAGG TGCAAGGCGC TTGGCCTCTC ATCGACAATA ATTACCTGAA CGTGCAGGTC 
ACCAATACAC CTGTGCTGCC CGGCTCTGCC GCCACTGCCA CCAGCAAGCT CACCATCATC 
TTCAAGAACT TCCAAGAGTG TGTGGACCAG AAAGTATACC AAGCCGAGAT GGACGAGCTT 
CCGTCCGCCT TTGCCGATGG CTCCAAAAAC GGTGGAGATA AACACGGAGC CAACAGCCTG 
AAGATCACAG AGAAGGTGTC AGGCCAGCAC GTGGAGATCC AGGCCAAGTA CATCGGCACC 
ACCATCGTGG TGAGACAGGT GGGCCGCTAC CTGACCTTCG CCGTCCGGAT GCCCGAGGAG 
GTAGTCAACG CCGTGGAGGA CCGTGACAGC CAAGGCCTCT ACCTCTGCCT GCGGGGCTGC 
CCGCTCAACC AGCAGATCGA CTTCCAGGCT TTCCGTGCCA ACGCCGAGAG CCCTCGCAGG 
CCAGCAGCTG CCAGCCCCTC TCCTGTGGTC CCCGAGACAT TTCCGTACGA GACAGCTGTG 
GCCAAGTGCA AAGAGAAGCT GCCTGTAGAA GACTTGTACT ACCAGGCCTG TGTCTTCGAC 
CTCCTCACGA CTGGCGACGT GAACTTCACG CTGGCCGCCT ACTATGCTTT GGAGGATGGC 
AAGATGCTCC ACTCCAACAA GGACAAGCTA CACCTGTTTG AAAGGACTCG GGAGCTGCCT 
GGCGCTGTGG CCGCTGCAGC ATTTCCCTTG GCCCCCGAGA TGCTCCCGGG CACCGTCACA 
CTTCTGGTCC TGCTGCCTCT GTTCTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rgma ( XM_008759521.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757743.1 Rattus norvegicus repulsive guidance molecule family member A (Rgma), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa46646
Clone ID Related Accession (Same CDS sequence)	XM_008759521.2
Accession Version	XM_008759521.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	repulsive guidance molecule A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759521.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGAAGA GACTGGATAA AGTTACTCCC CAGTTCACTG AGAAAGAACT TTGCTCCATC 
TCAGGTAAGG TCTCCCTGCA CCTCTCACCC AGAGAGATCT GTAGAAAAGG GTCCAACATG 
ATGGCACATC TGTTTTTCTC CATAGCTATC TCTCCCTGCA AGATCCTCAA GTGCAACTCT 
GAGTTCTGGA GCGCCACGTC GTCAGGCAGC CACGCCCCTG CCTCTGACGA CGTGCCCGAG 
TTCTGTGCTG CCCTGCGCAC CTACGCCCTG TGCACGCGAC GGACAGCCCG CACCTGCCGG 
GGCGACCTGG CTTACCACTC GGCTGTCCAT GGCATAGAGG ACCTCATGAG CCAGCACAAC 
TGCTCCAAGG ATGGCCCCAC CTCACAGCCT CGAGTGCGCA CGCTCCCGCC AGCTGGGGAC 
AGCCAGGAGC GCTCAGATAG CCCCGAGATC TGCCACTATG AGAAGAGTTT CCACAAGCAC 
TCAGCTGCCC CCAACTACAC TCACTGCGGC CTCTTTGGGG ACCCACACCT CAGGACTTTC 
ACAGACCACT TCCAGACATG TAAGGTGCAA GGCGCTTGGC CTCTCATCGA CAATAATTAC 
CTGAACGTGC AGGTCACCAA TACACCTGTG CTGCCCGGCT CTGCCGCCAC TGCCACCAGC 
AAGCTCACCA TCATCTTCAA GAACTTCCAA GAGTGTGTGG ACCAGAAAGT ATACCAAGCC 
GAGATGGACG AGCTTCCGTC CGCCTTTGCC GATGGCTCCA AAAACGGTGG AGATAAACAC 
GGAGCCAACA GCCTGAAGAT CACAGAGAAG GTGTCAGGCC AGCACGTGGA GATCCAGGCC 
AAGTACATCG GCACCACCAT CGTGGTGAGA CAGGTGGGCC GCTACCTGAC CTTCGCCGTC 
CGGATGCCCG AGGAGGTAGT CAACGCCGTG GAGGACCGTG ACAGCCAAGG CCTCTACCTC 
TGCCTGCGGG GCTGCCCGCT CAACCAGCAG ATCGACTTCC AGGCTTTCCG TGCCAACGCC 
GAGAGCCCTC GCAGGCCAGC AGCTGCCAGC CCCTCTCCTG TGGTCCCCGA GACATTTCCG 
TACGAGACAG CTGTGGCCAA GTGCAAAGAG AAGCTGCCTG TAGAAGACTT GTACTACCAG 
GCCTGTGTCT TCGACCTCCT CACGACTGGC GACGTGAACT TCACGCTGGC CGCCTACTAT 
GCTTTGGAGG ATGGCAAGAT GCTCCACTCC AACAAGGACA AGCTACACCT GTTTGAAAGG 
ACTCGGGAGC TGCCTGGCGC TGTGGCCGCT GCAGCATTTC CCTTGGCCCC CGAGATGCTC 
CCGGGCACCG TCACACTTCT GGTCCTGCTG CCTCTGTTCT GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757743.1
CDS	3685..5049
Translation	MRKRLDKVTPQFTEKELCSISGKVSLHLSPREICRKGSNMMAHLFFSIAISPCKILKCNSEFWSATSSGSHAPASDDVPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRVRTLPPAGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDHFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPSAFADGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQAFRANAESPRRPAAASPSPVVPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDGKMLHSNKDKLHLFERTRELPGAVAAAAFPLAPEMLPGTVTLLVLLPLFW

Target ORF information:

RefSeq Version	XM_008759521.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus repulsive guidance molecule family member A (Rgma), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759521.2

ORF Insert Sequence:

ATGAGGAAGA GACTGGATAA AGTTACTCCC CAGTTCACTG AGAAAGAACT TTGCTCCATC 
TCAGGTAAGG TCTCCCTGCA CCTCTCACCC AGAGAGATCT GTAGAAAAGG GTCCAACATG 
ATGGCACATC TGTTTTTCTC CATAGCTATC TCTCCCTGCA AGATCCTCAA GTGCAACTCT 
GAGTTCTGGA GCGCCACGTC GTCAGGCAGC CACGCCCCTG CCTCTGACGA CGTGCCCGAG 
TTCTGTGCTG CCCTGCGCAC CTACGCCCTG TGCACGCGAC GGACAGCCCG CACCTGCCGG 
GGCGACCTGG CTTACCACTC GGCTGTCCAT GGCATAGAGG ACCTCATGAG CCAGCACAAC 
TGCTCCAAGG ATGGCCCCAC CTCACAGCCT CGAGTGCGCA CGCTCCCGCC AGCTGGGGAC 
AGCCAGGAGC GCTCAGATAG CCCCGAGATC TGCCACTATG AGAAGAGTTT CCACAAGCAC 
TCAGCTGCCC CCAACTACAC TCACTGCGGC CTCTTTGGGG ACCCACACCT CAGGACTTTC 
ACAGACCACT TCCAGACATG TAAGGTGCAA GGCGCTTGGC CTCTCATCGA CAATAATTAC 
CTGAACGTGC AGGTCACCAA TACACCTGTG CTGCCCGGCT CTGCCGCCAC TGCCACCAGC 
AAGCTCACCA TCATCTTCAA GAACTTCCAA GAGTGTGTGG ACCAGAAAGT ATACCAAGCC 
GAGATGGACG AGCTTCCGTC CGCCTTTGCC GATGGCTCCA AAAACGGTGG AGATAAACAC 
GGAGCCAACA GCCTGAAGAT CACAGAGAAG GTGTCAGGCC AGCACGTGGA GATCCAGGCC 
AAGTACATCG GCACCACCAT CGTGGTGAGA CAGGTGGGCC GCTACCTGAC CTTCGCCGTC 
CGGATGCCCG AGGAGGTAGT CAACGCCGTG GAGGACCGTG ACAGCCAAGG CCTCTACCTC 
TGCCTGCGGG GCTGCCCGCT CAACCAGCAG ATCGACTTCC AGGCTTTCCG TGCCAACGCC 
GAGAGCCCTC GCAGGCCAGC AGCTGCCAGC CCCTCTCCTG TGGTCCCCGA GACATTTCCG 
TACGAGACAG CTGTGGCCAA GTGCAAAGAG AAGCTGCCTG TAGAAGACTT GTACTACCAG 
GCCTGTGTCT TCGACCTCCT CACGACTGGC GACGTGAACT TCACGCTGGC CGCCTACTAT 
GCTTTGGAGG ATGGCAAGAT GCTCCACTCC AACAAGGACA AGCTACACCT GTTTGAAAGG 
ACTCGGGAGC TGCCTGGCGC TGTGGCCGCT GCAGCATTTC CCTTGGCCCC CGAGATGCTC 
CCGGGCACCG TCACACTTCT GGTCCTGCTG CCTCTGTTCT GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.
Neuroscience letters662318-323(2018 Jan)
Wang Y,Zhang R,Xing X,Guo J,Xie F,Zhang G,Qin X

Lentiviral Vector-Induced Overexpression of RGMa in the Hippocampus Suppresses Seizures and Mossy Fiber Sprouting.
Molecular neurobiology54(2)1379-1391(2017 Mar)
Chen L,Gao B,Fang M,Li J,Mi X,Xu X,Wang W,Gu J,Tang B,Zhang Y,Wang Z,Zhan A,Chen G,Wang X

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.
Developmental cell35(5)537-52(2015 Dec)
van Erp S,van den Heuvel DM,Fujita Y,Robinson RA,Hellemons AJ,Adolfs Y,Van Battum EY,Blokhuis AM,Kuijpers M,Demmers JA,Hedman H,Hoogenraad CC,Siebold C,Yamashita T,Pasterkamp RJ

Potential roles of the RGMa-FAK-Ras pathway in hippocampal mossy fiber sprouting in the pentylenetetrazole kindling model.
Molecular medicine reports11(3)1738-44(2015 Mar)
Song MY,Tian FF,Wang YZ,Huang X,Guo JL,Ding DX