Dyrk1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dyrk1b
Entrez Gene ID	308468
Full Name	dual specificity tyrosine phosphorylation regulated kinase 1B
General protein information	Preferred Names dual specificity tyrosine phosphorylation regulated kinase 1B Names dual specificity tyrosine-phosphorylation-regulated kinase 1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21

mRNA and Protein(s)

mRNA	Protein	Name
XM_006228622.3	XP_006228684.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2
XM_006228623.3	XP_006228685.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X3
XM_006228624.2	XP_006228686.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X4
XM_006228621.3	XP_006228683.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1
NM_001107496.1	NP_001100966.1	dual specificity tyrosine-phosphorylation-regulated kinase 1B

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Dyrk1b	NP_001258299.1
Danio rerio (zebrafish)	dyrk1b	NP_001161737.1
	DYRK1B	XP_001089972.1
Bos taurus (cattle)	DYRK1B	NP_001074984.1
Rattus norvegicus (Norway rat)	Dyrk1b	NP_001100966.1
Xenopus tropicalis (tropical clawed frog)	dyrk1a.2	NP_001120373.1
Homo sapiens (human)	DYRK1B	NP_004705.1
Pan troglodytes (chimpanzee)	DYRK1B	XP_512657.2
Canis lupus familiaris (dog)	DYRK1B	XP_005616637.1

Gene Ontology
Bibliography

Related articles in PubMed

A form of the metabolic syndrome associated with mutations in DYRK1B.
Keramati AR, Fathzadeh M, Go GW, Singh R, Choi M, Faramarzi S, Mane S, Kasaei M, Sarajzadeh-Fard K, Hwa J, Kidd KK, Babaee Bigi MA, Malekzadeh R, Hosseinian A, Babaei M, Lifton RP, Mani A
The New England journal of medicine370(20)1909-1919(2014 May)

Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation.
Deng X, Ewton DZ, Pawlikowski B, Maimone M, Friedman E
The Journal of biological chemistry278(42)41347-54(2003 Oct)

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.
Lim S, Jin K, Friedman E
The Journal of biological chemistry277(28)25040-6(2002 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dyrk1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dyrk1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11258	NM_001107496.1 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00
ORa22506	XM_006228622.3 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa22507	XM_006228623.3 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa22505	XM_006228621.3 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
ORa22508	XM_006228624.2 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dyrk1b ( NM_001107496.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100966.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), mRNA.

Price & Availability↑

CloneID	ORa11258
Clone ID Related Accession (Same CDS sequence)	NM_001107496.1
Accession Version	NM_001107496.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473979.2. On or before Oct 4, 2007 this sequence version replaced XM_218378.4, XM_001078118.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGATAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGCTCCA GTGGCTCCTC CAGTGACAAC 
AGGGCCTACC GCTACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTACC TCTGGCTCAA CATTGCTGGG GACTGGGGCC 
CAGTTACCCC CACAACCCCG TTGCCTTGGA CGACCCCCAT CACCCACCTC ACCACCCCCC 
CCAGAGCTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCATCCA 
GCACCTGCTC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC GGGAGGTCGA 
CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGTCTGGG CCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100966.1
CDS	260..2029
Translation	MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPTSGSTLLGTGAQLPPQPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPHPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	NM_001107496.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107496.1

ORF Insert Sequence:

ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGATAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGCTCCA GTGGCTCCTC CAGTGACAAC 
AGGGCCTACC GCTACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTACC TCTGGCTCAA CATTGCTGGG GACTGGGGCC 
CAGTTACCCC CACAACCCCG TTGCCTTGGA CGACCCCCAT CACCCACCTC ACCACCCCCC 
CCAGAGCTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCATCCA 
GCACCTGCTC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC GGGAGGTCGA 
CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGTCTGGG CCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_006228622.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228684.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa22506
Clone ID Related Accession (Same CDS sequence)	XM_006228622.3
Accession Version	XM_006228622.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1986bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228622.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG CTCGCCCACC GCACTGGGGC CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCAGCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACACCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGACCTGGTG 
CTGCGCATGC TGGAGTATGA GCCCGCCGCC CGCATCAGCC CTCTGGGCGC TCTGCAGCAT 
GGCTTCTTCC GCCGCACGGC CGACGAGGCC ACCAACACGG GCCCGGCAGG CAGCAGTGCC 
TCCACCTCGC CGGCGCCCCT TGATACCTGC CCCTCCTCTA GCACCGCCAG CTCCATCTCC 
AGCTCTGGAG GCTCCAGTGG CTCCTCCAGT GACAACAGGG CCTACCGCTA CAGCAACCGA 
TATTGTGGGG GCCCAGGGCC CCCCATCACT GACTGTGAGA TGAACAGCCC CCAGGTCCTA 
CCCTCCCAGC CTCTGCGCCC CTGGGCAGGG GGTGATGTGC CCCACAAGAC ACATCAAGCC 
CCTACCTCTG GCTCAACATT GCTGGGGACT GGGGCCCAGT TACCCCCACA ACCCCGTTGC 
CTTGGACGAC CCCCATCACC CACCTCACCA CCCCCCCCAG AGCTGATGGA TGTGAGCCTG 
GTGGGCAGCC CTCCAGACTG CTCTCCACCT CATCCAGCAC CTGCTCCCCA GCACCCGGCT 
GCCTCAGCCC TCCGGACTCG GATGACGGGA GGTCGACCAC CTCTCCCGCC CCCTGATGAC 
CCTGCCACTC TGGGGCCTCG TCTGGGCCTC CATGGTGTAC CCCAGAGCAC AGCAGCCAGC 
TCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228684.1
CDS	235..2220
Translation	MLAARPPHWGPHRAPAPRGPSASPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPTSGSTLLGTGAQLPPQPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPHPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	XM_006228622.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228622.3

ORF Insert Sequence:

ATGCTGGCCG CTCGCCCACC GCACTGGGGC CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCAGCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACACCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGACCTGGTG 
CTGCGCATGC TGGAGTATGA GCCCGCCGCC CGCATCAGCC CTCTGGGCGC TCTGCAGCAT 
GGCTTCTTCC GCCGCACGGC CGACGAGGCC ACCAACACGG GCCCGGCAGG CAGCAGTGCC 
TCCACCTCGC CGGCGCCCCT TGATACCTGC CCCTCCTCTA GCACCGCCAG CTCCATCTCC 
AGCTCTGGAG GCTCCAGTGG CTCCTCCAGT GACAACAGGG CCTACCGCTA CAGCAACCGA 
TATTGTGGGG GCCCAGGGCC CCCCATCACT GACTGTGAGA TGAACAGCCC CCAGGTCCTA 
CCCTCCCAGC CTCTGCGCCC CTGGGCAGGG GGTGATGTGC CCCACAAGAC ACATCAAGCC 
CCTACCTCTG GCTCAACATT GCTGGGGACT GGGGCCCAGT TACCCCCACA ACCCCGTTGC 
CTTGGACGAC CCCCATCACC CACCTCACCA CCCCCCCCAG AGCTGATGGA TGTGAGCCTG 
GTGGGCAGCC CTCCAGACTG CTCTCCACCT CATCCAGCAC CTGCTCCCCA GCACCCGGCT 
GCCTCAGCCC TCCGGACTCG GATGACGGGA GGTCGACCAC CTCTCCCGCC CCCTGATGAC 
CCTGCCACTC TGGGGCCTCG TCTGGGCCTC CATGGTGTAC CCCAGAGCAC AGCAGCCAGC 
TCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_006228623.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228685.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa22507
Clone ID Related Accession (Same CDS sequence)	XM_006228623.3
Accession Version	XM_006228623.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1950bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228623.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG CTCGCCCACC GCACTGGGGC CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCAGCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACACCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGATAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGCTCCA GTGGCTCCTC CAGTGACAAC 
AGGGCCTACC GCTACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTACC TCTGGCTCAA CATTGCTGGG GACTGGGGCC 
CAGTTACCCC CACAACCCCG TTGCCTTGGA CGACCCCCAT CACCCACCTC ACCACCCCCC 
CCAGAGCTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCATCCA 
GCACCTGCTC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC GGGAGGTCGA 
CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGTCTGGG CCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228685.1
CDS	235..2184
Translation	MLAARPPHWGPHRAPAPRGPSASPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPTSGSTLLGTGAQLPPQPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPHPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	XM_006228623.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228623.3

ORF Insert Sequence:

ATGCTGGCCG CTCGCCCACC GCACTGGGGC CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCAGCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACACCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGATAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGCTCCA GTGGCTCCTC CAGTGACAAC 
AGGGCCTACC GCTACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTACC TCTGGCTCAA CATTGCTGGG GACTGGGGCC 
CAGTTACCCC CACAACCCCG TTGCCTTGGA CGACCCCCAT CACCCACCTC ACCACCCCCC 
CCAGAGCTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCATCCA 
GCACCTGCTC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC GGGAGGTCGA 
CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGTCTGGG CCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_006228621.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228683.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22505
Clone ID Related Accession (Same CDS sequence)	XM_006228621.3
Accession Version	XM_006228621.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2070bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228621.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCG CTCGCCCACC GCACTGGGGC CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCAGCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACACCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGTGCTGGGC 
GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CGGGCCACAG CCCCGCCGAC 
TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGATAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGCTCCA GTGGCTCCTC CAGTGACAAC 
AGGGCCTACC GCTACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTACC TCTGGCTCAA CATTGCTGGG GACTGGGGCC 
CAGTTACCCC CACAACCCCG TTGCCTTGGA CGACCCCCAT CACCCACCTC ACCACCCCCC 
CCAGAGCTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCATCCA 
GCACCTGCTC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC GGGAGGTCGA 
CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGTCTGGG CCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228683.1
CDS	235..2304
Translation	MLAARPPHWGPHRAPAPRGPSASPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPTSGSTLLGTGAQLPPQPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPHPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	XM_006228621.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228621.3

ORF Insert Sequence:

ATGCTGGCCG CTCGCCCACC GCACTGGGGC CCCCATCGCG CTCCAGCCCC CCGTGGGCCC 
AGCGCCAGCC CTGACCCGGG TCTCAGCGGC GGTGGCAGCC GAGGTGCAGG ATGCGAGAAG 
GCGCCCCCCG GCCGGGCTCC CGCTCCAGGC CTCACACCCC TGCGGCCCTC TGAGCCCACC 
ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGTGCTGGGC 
GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CGGGCCACAG CCCCGCCGAC 
TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGATAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGCTCCA GTGGCTCCTC CAGTGACAAC 
AGGGCCTACC GCTACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTACC TCTGGCTCAA CATTGCTGGG GACTGGGGCC 
CAGTTACCCC CACAACCCCG TTGCCTTGGA CGACCCCCAT CACCCACCTC ACCACCCCCC 
CCAGAGCTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCATCCA 
GCACCTGCTC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC GGGAGGTCGA 
CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGTCTGGG CCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk1b ( XM_006228624.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228686.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa22508
Clone ID Related Accession (Same CDS sequence)	XM_006228624.2
Accession Version	XM_006228624.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1890bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006228624.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGTGCTGGGC 
GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CGGGCCACAG CCCCGCCGAC 
TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGATAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGCTCCA GTGGCTCCTC CAGTGACAAC 
AGGGCCTACC GCTACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTACC TCTGGCTCAA CATTGCTGGG GACTGGGGCC 
CAGTTACCCC CACAACCCCG TTGCCTTGGA CGACCCCCAT CACCCACCTC ACCACCCCCC 
CCAGAGCTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCATCCA 
GCACCTGCTC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC GGGAGGTCGA 
CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGTCTGGG CCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228686.1
CDS	275..2164
Translation	MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPTSGSTLLGTGAQLPPQPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPHPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Target ORF information:

RefSeq Version	XM_006228624.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228624.2

ORF Insert Sequence:

ATGGCCGTCC CACCAGGCCA TGGTCCCTTC TCTGGCTTTC CGGGGCCCCA GGAACACACA 
CAGGTATTGC CTGATGTGCG GCTACTGCCA CGGAGACTGC CCCTGGCCTT CCGGGATGCG 
ACCTCGGCCC CGCTGCGCAA GCTCTCAGTG GACCTCATCA AGACCTACAA GCACATCAAT 
GAGGTATACT ATGCGAAGAA GAAGCGGCGG GCCCAACAGG CGCCACCCCA GGACTCGAGC 
ACCAAAAAGG AGAAGAAGGT CCTGAATCAC GGCTATGACG ATGACAACCA CGACTACATT 
GTGCGCAGCG GCGAGCGCTG GCTAGAGCGC TATGAAATTG ACTCTCTTAT TGGCAAAGGC 
TCTTTTGGCC AGGTGGTGAA AGCCTATGAT CACCAGACTC AGGAGCTGGT GGCCATCAAG 
ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TTGAGCTGAG GCTGCTGGAG 
CTGATGAATC AGCATGATAC AGAGATGAAG TACTACATAG TACACCTGAA GCGGCACTTC 
ATGTTCCGGA ATCACCTGTG CCTGGTGTTT GAGCTGCTGT CCTACAACCT GTACGACCTC 
CTCCGCAACA CACACTTTCG CGGTGTCTCA CTGAACCTGA CGAGGAAGCT GGCACAGCAG 
CTCTGCACAG CCCTGCTCTT TCTGGCCACG CCTGAGCTCA GCATCATCCA CTGCGACCTC 
AAGCCTGAGA ACATCCTGCT CTGCAATCCT AAGCGCAGCG CCATCAAGAT TGTGGACTTC 
GGCAGCTCCT GCCAGCTTGG CCAGCGGATC TACCAGTATA TCCAGAGCCG CTTCTACCGC 
TCACCAGAGG TGCTCCTGGG TACACCCTAT GACCTGGCCA TCGACATGTG GTCCCTGGGC 
TGCATCCTTG TGGAGATGCA CACCGGAGAA CCCCTCTTCA GTGGCTCTAA TGAGGTGGAC 
CAGATGAGCC GGATTGTGGA GGTGTTGGGC ATCCCTCCCG CACCTATGCT GGAACAGGCA 
CCCAAAGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGAAGGACA 
AAGGAACTCA GGAAGGATTA CCAGGGCCCT GGGACACGGC GGCTGCAGGA GGTGCTGGGC 
GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CGGGCCACAG CCCCGCCGAC 
TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAGT ATGAGCCCGC CGCCCGCATC 
AGCCCTCTGG GCGCTCTGCA GCATGGCTTC TTCCGCCGCA CGGCCGACGA GGCCACCAAC 
ACGGGCCCGG CAGGCAGCAG TGCCTCCACC TCGCCGGCGC CCCTTGATAC CTGCCCCTCC 
TCTAGCACCG CCAGCTCCAT CTCCAGCTCT GGAGGCTCCA GTGGCTCCTC CAGTGACAAC 
AGGGCCTACC GCTACAGCAA CCGATATTGT GGGGGCCCAG GGCCCCCCAT CACTGACTGT 
GAGATGAACA GCCCCCAGGT CCTACCCTCC CAGCCTCTGC GCCCCTGGGC AGGGGGTGAT 
GTGCCCCACA AGACACATCA AGCCCCTACC TCTGGCTCAA CATTGCTGGG GACTGGGGCC 
CAGTTACCCC CACAACCCCG TTGCCTTGGA CGACCCCCAT CACCCACCTC ACCACCCCCC 
CCAGAGCTGA TGGATGTGAG CCTGGTGGGC AGCCCTCCAG ACTGCTCTCC ACCTCATCCA 
GCACCTGCTC CCCAGCACCC GGCTGCCTCA GCCCTCCGGA CTCGGATGAC GGGAGGTCGA 
CCACCTCTCC CGCCCCCTGA TGACCCTGCC ACTCTGGGGC CTCGTCTGGG CCTCCATGGT 
GTACCCCAGA GCACAGCAGC CAGCTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A form of the metabolic syndrome associated with mutations in DYRK1B.
The New England journal of medicine370(20)1909-1919(2014 May)
Keramati AR,Fathzadeh M,Go GW,Singh R,Choi M,Faramarzi S,Mane S,Kasaei M,Sarajzadeh-Fard K,Hwa J,Kidd KK,Babaee Bigi MA,Malekzadeh R,Hosseinian A,Babaei M,Lifton RP,Mani A

Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation.
The Journal of biological chemistry278(42)41347-54(2003 Oct)
Deng X,Ewton DZ,Pawlikowski B,Maimone M,Friedman E

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.
The Journal of biological chemistry277(28)25040-6(2002 Jul)
Lim S,Jin K,Friedman E

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Dyrk1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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