Cops6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cops6
Entrez Gene ID	304343
Full Name	COP9 signalosome subunit 6
General protein information	Preferred Names COP9 signalosome subunit 6 Names COP9 signalosome complex subunit 6 COP9 (constitutive photomorphogenic) homolog, subunit 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107129.1	NP_001100599.1	COP9 signalosome complex subunit 6

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	cops6	NP_001017768.1
Drosophila melanogaster (fruit fly)	CSN6	NP_524451.1
Magnaporthe oryzae (rice blast fungus)	MGG_01432	XP_003714381.1
Neurospora crassa	NCU07019	XP_961840.1
Arabidopsis thaliana (thale cress)	CSN6A	NP_568839.1
Arabidopsis thaliana (thale cress)	CSN6B	NP_567746.1
Xenopus tropicalis (tropical clawed frog)	cops6	NP_001006723.1
Pan troglodytes (chimpanzee)	COPS6	XP_001146264.1
Caenorhabditis elegans (roundworm)	csn-6	NP_001255725.1
Homo sapiens (human)	COPS6	NP_006824.2
Rattus norvegicus (Norway rat)	Cops6	NP_001100599.1
	LOC710667	XP_001100125.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008156	XP_317307.4
Canis lupus familiaris (dog)	COPS6	XP_536866.3
Bos taurus (cattle)	COPS6	NP_001095433.1
Mus musculus (house mouse)	Cops6	NP_036132.1
Oryza sativa (rice)	Os08g0500000	NP_001062152.2

Gene Ontology
Bibliography

Related articles in PubMed

Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality.
Sharon M, Mao H, Boeri Erba E, Stephens E, Zheng N, Robinson CV
Structure (London, England : 1993)17(1)31-40(2009 Jan)

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry.
Fang L, Wang X, Yamoah K, Chen PL, Pan ZQ, Huang L
Journal of proteome research7(11)4914-25(2008 Nov)

The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.
Wei N, Tsuge T, Serino G, Dohmae N, Takio K, Matsui M, Deng XW
Current biology : CB8(16)919-22(1998 Jul 30-Aug 13)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cops6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cops6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11981	NM_001107129.1 Latest version!	Rattus norvegicus COP9 signalosome subunit 6 (Cops6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cops6 ( NM_001107129.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100599.1 Rattus norvegicus COP9 signalosome subunit 6 (Cops6), mRNA.

Price & Availability↑

CloneID	ORa11981
Clone ID Related Accession (Same CDS sequence)	NM_001107129.1
Accession Version	NM_001107129.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	COP9 signalosome complex subunit 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474107.1. On or before Oct 4, 2007 this sequence version replaced XM_222002.3, XM_001066309.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAAAGGG GCGGGCCGTG GCTGGCGGGC GCGGGGAAAA TGGCGGCGGC GGCGGCGGCG 
GCTGCGGCGG CGGCGGCGGC GGCGGCGAAC GGGAGCGGAG GCAGCAGCGG CATGGAGGTG 
GATGCAGCAG TCCCCAGCGT GATGGCCTCC GGAGTGACTG GGAGTGTTTC CGTCGCTCTT 
CATCCCCTTG TCATCCTCAA CATCTCAGAC CATTGGATCC GCATGCGCTC CCAGGAGGGG 
CGGCCTATGC AGGTGATTGG GGCTCTGATC GGGAAGCAGG AGGGGCGAAA TATCGAAGTG 
ATGAACTCCT TTGAGCTGCT GTCTCACACC GTGGAAAAGA AGATTATCAT TGACAAAGAA 
TATTATTACA CCAAGGAGGA GCAGTTTAAA CAGGTTTTCA AGGAGCTGGA GTTTTTGGGT 
TGGTATACCA CAGGGGGGCC ACCTGACCCC TCAGACATCC ACGTCCATAA GCAGGTTTGC 
GAGATAATTG AGAGTCCTCT CTTTCTGAAG TTGAACCCTA TGACCAAGCA CACAGATCTG 
CCTGTCAGCG TTTTTGAGTC TGTCATCGAT ATAATCAATG GAGAGGCCAC AATGCTGTTT 
GCTGAACTCA CTTACACTCT GGCCACTGAG GAAGCTGAAC GTATCGGTGT AGACCATGTG 
GCCCGGATGA CAGCTACAGG CAGTGGGGAG AACTCCACTG TGGCTGAACA CCTCATAGCT 
CAGCACAGCG CCATCAAGAT GCTGCACAGC CGTGTGAAGC TCATTTTAGA GTACGTCAAG 
GCCTCTGAAG CAGGAGAGGT TCCCTTCAAC CATGAGATCC TGCGGGAGGC CTATGCCCTA 
TGCCACTGTC TTCCAGTTCT CAGCACTGAC AAGTTCAAGA CAGACTTTTA TGATCAATGC 
AATGACGTGG GGCTTATGGC CTACCTCGGC ACCATCACCA AAACGTGCAA CACAATGAAC 
CAGTTTGTGA ACAAGTTCAA CGTCCTGTAT GACCGACAAG GCATCGGCAG GCGGATGCGG 
GGACTGTTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100599.1
CDS	3..1037
Translation	MERGGPWLAGAGKMAAAAAAAAAAAAAAANGSGGSSGMEVDAAVPSVMASGVTGSVSVALHPLVILNISDHWIRMRSQEGRPMQVIGALIGKQEGRNIEVMNSFELLSHTVEKKIIIDKEYYYTKEEQFKQVFKELEFLGWYTTGGPPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTDLPVSVFESVIDIINGEATMLFAELTYTLATEEAERIGVDHVARMTATGSGENSTVAEHLIAQHSAIKMLHSRVKLILEYVKASEAGEVPFNHEILREAYALCHCLPVLSTDKFKTDFYDQCNDVGLMAYLGTITKTCNTMNQFVNKFNVLYDRQGIGRRMRGLFF

Target ORF information:

RefSeq Version	NM_001107129.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus COP9 signalosome subunit 6 (Cops6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107129.1

ORF Insert Sequence:

ATGGAAAGGG GCGGGCCGTG GCTGGCGGGC GCGGGGAAAA TGGCGGCGGC GGCGGCGGCG 
GCTGCGGCGG CGGCGGCGGC GGCGGCGAAC GGGAGCGGAG GCAGCAGCGG CATGGAGGTG 
GATGCAGCAG TCCCCAGCGT GATGGCCTCC GGAGTGACTG GGAGTGTTTC CGTCGCTCTT 
CATCCCCTTG TCATCCTCAA CATCTCAGAC CATTGGATCC GCATGCGCTC CCAGGAGGGG 
CGGCCTATGC AGGTGATTGG GGCTCTGATC GGGAAGCAGG AGGGGCGAAA TATCGAAGTG 
ATGAACTCCT TTGAGCTGCT GTCTCACACC GTGGAAAAGA AGATTATCAT TGACAAAGAA 
TATTATTACA CCAAGGAGGA GCAGTTTAAA CAGGTTTTCA AGGAGCTGGA GTTTTTGGGT 
TGGTATACCA CAGGGGGGCC ACCTGACCCC TCAGACATCC ACGTCCATAA GCAGGTTTGC 
GAGATAATTG AGAGTCCTCT CTTTCTGAAG TTGAACCCTA TGACCAAGCA CACAGATCTG 
CCTGTCAGCG TTTTTGAGTC TGTCATCGAT ATAATCAATG GAGAGGCCAC AATGCTGTTT 
GCTGAACTCA CTTACACTCT GGCCACTGAG GAAGCTGAAC GTATCGGTGT AGACCATGTG 
GCCCGGATGA CAGCTACAGG CAGTGGGGAG AACTCCACTG TGGCTGAACA CCTCATAGCT 
CAGCACAGCG CCATCAAGAT GCTGCACAGC CGTGTGAAGC TCATTTTAGA GTACGTCAAG 
GCCTCTGAAG CAGGAGAGGT TCCCTTCAAC CATGAGATCC TGCGGGAGGC CTATGCCCTA 
TGCCACTGTC TTCCAGTTCT CAGCACTGAC AAGTTCAAGA CAGACTTTTA TGATCAATGC 
AATGACGTGG GGCTTATGGC CTACCTCGGC ACCATCACCA AAACGTGCAA CACAATGAAC 
CAGTTTGTGA ACAAGTTCAA CGTCCTGTAT GACCGACAAG GCATCGGCAG GCGGATGCGG 
GGACTGTTTT TCTGA