Zscan21 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Zscan21
Entrez Gene ID	304342
Full Name	zinc finger and SCAN domain containing 21
Synonyms	Zipro1
General protein information	Preferred Names zinc finger and SCAN domain containing 21 Names zinc finger and SCAN domain-containing protein 21 zinc finger proliferation 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012021.2	NP_001012021.1	zinc finger and SCAN domain-containing protein 21

Pathways from BioSystems

Homologies

Homo sapiens (human)	ZSCAN21	NP_666019.1
Pan troglodytes (chimpanzee)	ZSCAN21	NP_001129089.1
	ZSCAN21	XP_001099642.1
Bos taurus (cattle)	ZSCAN21	NP_001030445.1
Rattus norvegicus (Norway rat)	Zscan21	NP_001012021.1
Mus musculus (house mouse)	Zscan21	NP_001038168.1

Gene Ontology
Bibliography

Related articles in PubMed

Complex Effects of the ZSCAN21 Transcription Factor on Transcriptional Regulation of ?-Synuclein in Primary Neuronal Cultures and in Vivo.
Dermentzaki G, Paschalidis N, Politis PK, Stefanis L
The Journal of biological chemistry291(16)8756-72(2016 Apr)

Functional dissection of the alpha-synuclein promoter: transcriptional regulation by ZSCAN21 and ZNF219.
Clough RL, Dermentzaki G, Stefanis L
Journal of neurochemistry110(5)1479-90(2009 Sep)

Induction of zinc-finger proliferation 1 expression in non-myelinating Schwann cells after denervation.
Ellerton EL, Thompson WJ, Rimer M
Neuroscience153(4)975-85(2008 Jun)

A novel profile of expressed sequence tags for zinc finger encoding genes from the poorly differentiated exocrine pancreatic cell line AR4IP.
Gebelein B, Mesa K, Urrutia R
Cancer letters105(2)225-31(1996 Aug)

Granule cell specification in the developing mouse brain as defined by expression of the zinc finger transcription factor RU49.
Yang XW, Zhong R, Heintz N
Development (Cambridge, England)122(2)555-66(1996 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the unaltered SNCA levels observed following ZSCAN21 down-regulation in the rat brain, possibly due to compensatory mechanisms, imply that ZSCAN21 is not a master regulator of SNCA in vivo.
Title: Complex Effects of the ZSCAN21 Transcription Factor on Transcriptional Regulation of ?-Synuclein in Primary Neuronal Cultures and in Vivo.

Transcription factor zinc finger and SCAN domain containing (ZSCAN)21, which binds to a site within intron 1, is a key regulator of alpha-synuclein transcription in neuronal cells.
Title: Functional dissection of the alpha-synuclein promoter: transcriptional regulation by ZSCAN21 and ZNF219.

Zipro1 is a good candidate for a transcription factor involved in activation of non-myelinating cervical sympathetic trunk.
Title: Induction of zinc-finger proliferation 1 expression in non-myelinating Schwann cells after denervation.

The following Zscan21 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zscan21 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01980	NM_001012021.2 Latest version!	Rattus norvegicus zinc finger and SCAN domain containing 21 (Zscan21), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Zscan21 ( NM_001012021.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012021.1 Rattus norvegicus zinc finger and SCAN domain containing 21 (Zscan21), mRNA.

Price & Availability↑

CloneID	ORa01980
Clone ID Related Accession (Same CDS sequence)	NM_001012021.2
Accession Version	NM_001012021.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1665bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	zinc finger and SCAN domain-containing protein 21
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FM121830.1, BC079435.1 and BG379149.1. On Jan 1, 2009 this sequence version replaced NM_001012021.1. ##Evidence-Data-START## Transcript exon combination :: BC079435.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCAAGG TGGTGGGCAT GGCCACAGTT CTGGGCCCCA GGCCACCTCA GGAGTCTATG 
GGACCTTCGC CCATTAAAGT TGAAGAGGAT GAAGAAAAAG ACAAGTGCCG CCCTAGCCTA 
GAGCTATCCC GAAAGCGCTT CAGGCAGTCT AGAAACCAGG ACACTCTTGA GCCAATGGGA 
CCTTCAACCA TTAAAGCTGA AGAGGAGGAA GACAAGGACA AGGGCCACCC TAGCCTAGAG 
CTATCCCGTA AGAGCTTCAA GCAGTTTGGG TACCATGACA CTTTGGAACA GTTGGGACCT 
TCGACTGTTA AAGCTGAAGA GGATGAAGAG AAGGACAAGG GCCGCCCTAG CCTAGAGATA 
TCCCGTCAGC GCTTCAGGCA GTTTGGGTAC CATGACACTC CTGGGCCCCG AGAGGCACTG 
AGCCAGCTTC GGGTGCTCTG CTGTGAGTGG CTACAGCCTG AGATCCACAC CAAGGAGCAG 
ATTCTAGAGC TACTGGTTCT GGAGCAGTTC CTGACCATCC TGCCCCGAGA GCTCCAGGCC 
TGGGTACAGC AGCACTGCCC TGAGAGTGCA GAGGAGGCCG TCACTCTCCT GGAAGACCTG 
GAGCAAGAAC TGGATGAGCC TGGACTGCAG GTCTCATCTC CAAATGAACA GAAGCAGTCT 
TGGGAGAAAA TATCAACTTC AGGAACTGCA ATGGAGTCCT TAAGCAGCAC TGAGACCCAG 
CCTGTGGATG CCAGCCCTAA ATATGAGTTT TGGGGGCCCC TGTACATCCA AGAGACTGGT 
GAAGAGGAGG TTTTCACTCA GGACCCAAGA AAGCGCCAAG GTTTTAAATT GAATCCGCAG 
AAGGAGGACT CAGCAGATGA GCAGAGAAGT TCTGAAGAAG AGTCTCATGC AGGTGGACTC 
AAAAGAAACA TCATGCCCAT GATCACTGCC AATAAGTATG GATCGAGGTC AGAAAGGCAG 
TGGGCCAACA ACCTGGAAAG GGAGAGAGGG GCAAAAGCCT CTCTTCAAGA CACGGGATCC 
AGGAAAGGGG CAGAACCAGC GTCTGCTAGG CCTGCTCCAG GAGAGAAACG TTACATATGT 
GCAGAGTGTG GGAAGGCCTT TAGCAATAGC TCAAACCTCA CTAAACACCG GAGAACACAC 
ACTGGGGAGA AGCCTTACGT GTGCACCAAG TGTGGGAAGG CTTTCAGCCA CAGCTCCAAC 
CTTACCCTTC ATTACCGGAC ACATCTGGTG GACCGGCCCT ATGACTGTAA GTGTGGGAAA 
GCCTTTGGGC AGAGCTCAGA CCTCCTTAAA CATCAGAGGA TGCACACAGA AGAGGCGCCC 
TATCAGTGTA AAGACTGTGG GAAAGCCTTC AGTGGGAAGG GCAGCCTCAT TCGACACTAT 
CGCATCCACA CAGGGGAGAA GCCCTATCAG TGCAATGAGT GTGGAAAGAG TTTTAGTCAG 
CATGCAGGTC TCAGTTCCCA TCAACGCCTG CATACAGGGG AGAAACCCTA TAAGTGTAAG 
GAGTGTGGCA AAGCCTTCAA CCATAGTTCG AATTTTAATA AGCATCACAG AATCCATACT 
GGTGAAAAAC CCTATTGGTG TAACCACTGT GGGAAAACCT TCTGTAGCAA GTCAAATCTT 
TCCAAGCATC AGAGAGTCCA CACTGGAGAG GGAGAGGTAC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012021.1
CDS	167..1831
Translation	MTKVVGMATVLGPRPPQESMGPSPIKVEEDEEKDKCRPSLELSRKRFRQSRNQDTLEPMGPSTIKAEEEEDKDKGHPSLELSRKSFKQFGYHDTLEQLGPSTVKAEEDEEKDKGRPSLEISRQRFRQFGYHDTPGPREALSQLRVLCCEWLQPEIHTKEQILELLVLEQFLTILPRELQAWVQQHCPESAEEAVTLLEDLEQELDEPGLQVSSPNEQKQSWEKISTSGTAMESLSSTETQPVDASPKYEFWGPLYIQETGEEEVFTQDPRKRQGFKLNPQKEDSADEQRSSEEESHAGGLKRNIMPMITANKYGSRSERQWANNLERERGAKASLQDTGSRKGAEPASARPAPGEKRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCNHCGKTFCSKSNLSKHQRVHTGEGEVQ

Target ORF information:

RefSeq Version	NM_001012021.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger and SCAN domain containing 21 (Zscan21), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012021.2

ORF Insert Sequence:

ATGACCAAGG TGGTGGGCAT GGCCACAGTT CTGGGCCCCA GGCCACCTCA GGAGTCTATG 
GGACCTTCGC CCATTAAAGT TGAAGAGGAT GAAGAAAAAG ACAAGTGCCG CCCTAGCCTA 
GAGCTATCCC GAAAGCGCTT CAGGCAGTCT AGAAACCAGG ACACTCTTGA GCCAATGGGA 
CCTTCAACCA TTAAAGCTGA AGAGGAGGAA GACAAGGACA AGGGCCACCC TAGCCTAGAG 
CTATCCCGTA AGAGCTTCAA GCAGTTTGGG TACCATGACA CTTTGGAACA GTTGGGACCT 
TCGACTGTTA AAGCTGAAGA GGATGAAGAG AAGGACAAGG GCCGCCCTAG CCTAGAGATA 
TCCCGTCAGC GCTTCAGGCA GTTTGGGTAC CATGACACTC CTGGGCCCCG AGAGGCACTG 
AGCCAGCTTC GGGTGCTCTG CTGTGAGTGG CTACAGCCTG AGATCCACAC CAAGGAGCAG 
ATTCTAGAGC TACTGGTTCT GGAGCAGTTC CTGACCATCC TGCCCCGAGA GCTCCAGGCC 
TGGGTACAGC AGCACTGCCC TGAGAGTGCA GAGGAGGCCG TCACTCTCCT GGAAGACCTG 
GAGCAAGAAC TGGATGAGCC TGGACTGCAG GTCTCATCTC CAAATGAACA GAAGCAGTCT 
TGGGAGAAAA TATCAACTTC AGGAACTGCA ATGGAGTCCT TAAGCAGCAC TGAGACCCAG 
CCTGTGGATG CCAGCCCTAA ATATGAGTTT TGGGGGCCCC TGTACATCCA AGAGACTGGT 
GAAGAGGAGG TTTTCACTCA GGACCCAAGA AAGCGCCAAG GTTTTAAATT GAATCCGCAG 
AAGGAGGACT CAGCAGATGA GCAGAGAAGT TCTGAAGAAG AGTCTCATGC AGGTGGACTC 
AAAAGAAACA TCATGCCCAT GATCACTGCC AATAAGTATG GATCGAGGTC AGAAAGGCAG 
TGGGCCAACA ACCTGGAAAG GGAGAGAGGG GCAAAAGCCT CTCTTCAAGA CACGGGATCC 
AGGAAAGGGG CAGAACCAGC GTCTGCTAGG CCTGCTCCAG GAGAGAAACG TTACATATGT 
GCAGAGTGTG GGAAGGCCTT TAGCAATAGC TCAAACCTCA CTAAACACCG GAGAACACAC 
ACTGGGGAGA AGCCTTACGT GTGCACCAAG TGTGGGAAGG CTTTCAGCCA CAGCTCCAAC 
CTTACCCTTC ATTACCGGAC ACATCTGGTG GACCGGCCCT ATGACTGTAA GTGTGGGAAA 
GCCTTTGGGC AGAGCTCAGA CCTCCTTAAA CATCAGAGGA TGCACACAGA AGAGGCGCCC 
TATCAGTGTA AAGACTGTGG GAAAGCCTTC AGTGGGAAGG GCAGCCTCAT TCGACACTAT 
CGCATCCACA CAGGGGAGAA GCCCTATCAG TGCAATGAGT GTGGAAAGAG TTTTAGTCAG 
CATGCAGGTC TCAGTTCCCA TCAACGCCTG CATACAGGGG AGAAACCCTA TAAGTGTAAG 
GAGTGTGGCA AAGCCTTCAA CCATAGTTCG AATTTTAATA AGCATCACAG AATCCATACT 
GGTGAAAAAC CCTATTGGTG TAACCACTGT GGGAAAACCT TCTGTAGCAA GTCAAATCTT 
TCCAAGCATC AGAGAGTCCA CACTGGAGAG GGAGAGGTAC AGTAA