Safb2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Safb2
Entrez Gene ID	301126
Full Name	scaffold attachment factor B2
General protein information	Preferred Names scaffold attachment factor B2 Names scaffold attachment factor B2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001303144.1	NP_001290073.1	scaffold attachment factor B2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SAFB2	XP_512297.2
Rattus norvegicus (Norway rat)	Safb2	XP_006244425.1
Canis lupus familiaris (dog)	SAFB2	XP_533945.3
Homo sapiens (human)	SAFB2	NP_055464.1
Mus musculus (house mouse)	Safb2	NP_001025150.2
	SAFB2	XP_001084042.1
Bos taurus (cattle)	SAFB2	NP_001243483.1

Gene Ontology
Bibliography

Related articles in PubMed

Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1.
Jiang S, Katz TA, Garee JP, DeMayo FJ, Lee AV, Oesterreich S
Disease models & mechanisms8(9)1121-7(2015 Sep)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.
Tsianou D, Nikolakaki E, Tzitzira A, Bonanou S, Giannakouros T, Georgatsou E
The FEBS journal276(18)5212-27(2009 Sep)

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.
Kang D, Oh S, Ahn SM, Lee BH, Moon MH
Journal of proteome research7(8)3475-80(2008 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Safb2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Safb2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa18246	NM_001303144.1 Latest version!	Rattus norvegicus scaffold attachment factor B2 (Safb2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Safb2 ( NM_001303144.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001290073.1 Rattus norvegicus scaffold attachment factor B2 (Safb2), mRNA.

Price & Availability↑

CloneID	ORa18246
Clone ID Related Accession (Same CDS sequence)	NM_001303144.1
Accession Version	NM_001303144.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2976bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Rattus norvegicus(Norway rat)
Product	scaffold attachment factor B2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07066522.1. On or before Dec 19, 2014 this sequence version replaced XM_002730092.4, XM_002727153.4. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: FQ221088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAAC CTGTGACCGG GTCGGGCGAC CCGGCTTTTA GTCCGGTCGC TTCGGATAGT 
GGGATGCGGC GGCTCAGCGA CCTGCGGGTG ATCGACCTGA GGGCGGAGCT GAAGAAGCGG 
AACCTGGATA CAGGAGGCAA CAAGAGTGTG TTGATGGAGC GGCTGAAGAA GGCATTTAAA 
GAGGAAGGAC AAGAACCTGA GGAAGTCGGT ATCAGTTGGG GAGCTGTAAG CAAGAGGGCT 
ATAAAGAGAA ACACCAAAGG GGCCAAGATG GAGGAGGAGG GCGGTGAGGA CACCGGCCTG 
GAGGAAGATT CCAGAGATGG GCAGGATGAG ACTGTGATTC TTCAGAGTTC ACAAGACAGG 
GACACTGTGG ATACAGGTGT GCCAGATGGG ATGGAGGCTC AGGACCTCAG TGTGCCCTGC 
CTGGGGAAGG CCGACACCGA CAAACAGTCT CTTGATGCCT TTGATGACAG TAAAGAGTAC 
GTGGCCGCGC AGCTGGGACA GCTTCCAGCT CAGCTCCTGA AGCATGCTGT GAATGAGGAT 
GTCTTCAAGA ACACTCTGGA AGCTTCCATG TCAGACCTTA AAGTAACTAT GGCTGGTGAA 
GAAGCCCCGT TGGAACCAGA AAATGAGAAA ATACTCGACA TTTTGGGGGA AACTTGTAAA 
TCTGAGCCAG TAAAAGAAGA AGGTTCGGAG CTGGAGCAGC CCTTTGCCCA GGCCACGAGT 
AGCGTGGGGC CAGACAGGAA GCTGGCGGAG GAAGAGGACC TATTTGAGAG CTGCGGCCAC 
CCGGAAGAGG AAGAAGAAGA GGAGGAAGAA GAGGAGCAGG AAGAGGAGCA GGAGGAGGAG 
GGAGATTTAG CTTTGGCCAG CAGCAGCAAG TCTGAGTCTT CAAGCACTCG ATGTCAGTGG 
AGCGAGGCAG ACGCCCTGTT AGCAGTAGTG AAAAGGGAGC CGGCAGAGGC GCCTGGTGGA 
GGCGGAGGTA CTCAGCACTG GCGGAAGCGA AAGCGAAGGC GGAAGCATCA GGCAGAGGCA 
GAAGCTCTGG GCACGGGTGG AGGTACCTGG ATGAACCGCG AGCCTGTAGG GCTAGAGGAG 
CCAGTTGAAC AGAGTAGCAC GGCTGCCCAG CTCCCGGAGG CCACCAGCCA GGAGCTGGTG 
CGAGCGCCCA CGGCAGCCCC GAGCCCTGAG CCCCGAGATA GCAAAGACGA CGTGAAGAAG 
TTTGCTTTTG ACGCTTGTAA TGACGTCCCT GCGGCTCCTA AAGAGTCCTC AGCCAGTGAG 
GGTGCTGATC AGAAAATGAG CTTTGTTAAG GAAGAACAGG ATATAAAGCC AGTCATTAAA 
GACGAGAAAG GCCGTGCCAG CTGTAGCTCA GGAAGGAACC TGTGGGTCAG TGGACTGTCC 
TCCAGCACAC GTGCTGCTGA TCTCAAGAGC CTCTTCAGCA AGCATGGGAA GGTCATTGGA 
GCCAAGGTGG TTACCAATGC CCGCAGTCCT GGAGCTCGAT GCTATGGATT TGTGACCATG 
TCCATGTCAG ATGAGGCCAC CAAATGCATC AACCACCTGC ACAGAACAGA ACTGCATGGA 
AGGATGATCT CTGTGGAGAA GGCCAAAAAT GAGCCCTCTG AGAAGAAGTC AGCAGACAGG 
AGAGCTTGTG ACCAAAAGGA GAAGGTGCCA GGGCCAGACA GGCCTCACCC TGTGAAGATC 
AAGATGGAGA AAACTGTGAT CAAAAAGGAA GAGAAACTGG AAAGAAAGGA AGAGAAAGGG 
CCAGAGGACA TTAAGAAGGA GAAGGATCAA GATGAGCTTC CACCAGGAAC CGCCAGTCAT 
TCTCGAGTAA CCAAATCAGG AAGCAGATGC ACGGAGCGTA CAGTCGTGAT GGACAAGTCC 
AAGGGCGAGC CCGTCATCAG TGTGAAGGCC ACAAGCAGGT CAAAGGACAG AAGCTCCAAA 
AGTCAAGACC GAAAGTCAGA GGGCAGGGAG AAGAGAGACA TATTGTCATT TGACAAGATC 
AAGGAGCAGC GGGAGCGGGA GCGCCAGAGG CAGAGGGAGC GTGAAATCCG GGAGACCGAG 
CGGCGACGGG AGCGGGAGCA GCGAGAGCGG GAGCAGCGTC TGGATGCCTT CCAGGAGCGG 
CGGGAGAAGG CTCGTTTGCA GCGAGAACGG CTGCAGCTCC AATGCCAGCG GCAGCGTCTA 
GAAAGGGAGC GGCTGGAGAG GGAGAGACTG GAGAGGGAGC GCATGCGAGT GGAGCGTGAA 
AGGCGCAAGG AACAGCAGCG CATTATGCGT GAGCGTGAGG AGCTGCGACG GCAGCAAGAG 
CAGCTGCGGG CTGAGCAGGA ACGGCGAGCA TTGCGCAGAG CCTACAACCT GGATGCTAGG 
AGAGATGATG GCTACTGGCC AGAAGGGAAG CGTGCAGCCA TGGAAGACAG ATATCGAGAC 
TTTCCAAGGC CAGATCACCG TTTCCATGAC TTCGATCACC GGGAACGGGG TCATTACCAG 
GAGCATGTTA TAGACAGGAG GGATGGGTCC AGACCCAGAA TGGAAGAGCG GGATGGGCCG 
TACTACCCAG ATGACCAGCA CAGCCATGGA AGGCCTCTGG AGCACCATGG TTGGGACGCC 
CGAGACGGCT GGCATGGCTA CAGCTCTGAC AAGAAGTTGA ATGAAGGCCT AGGGCTACCC 
CCTCCCCCCA GGGTCAGCCG AGAATGGGCA GAGCACAGCT CACAGTTGGA GGAGCAGCAG 
GTTCCTGTCT GGCACAACGC TGTGGACACA AACATGACGG GCCATGAACA CATACGGTGG 
CGAGGTGCTG AGCGGGGCCT TACAGGACCT GGGCATGGGC ATGTGGCAGC AGGCCGGGGT 
GGCATGGCTG GGCAAGGCAG CTTTGCACAC GGTGAACATT CCCAGGGCCA TATTATGCCT 
AGTGGTAGAC TGGAAGGTGG TGGCGTGGCC AGCCAGGACC AGGGTGGCCG AATTCCCAAC 
TCCCACCCTC ACCCCCACTT CACCCGCCGC TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290073.1
CDS	92..3067
Translation	MAEPVTGSGDPAFSPVASDSGMRRLSDLRVIDLRAELKKRNLDTGGNKSVLMERLKKAFKEEGQEPEEVGISWGAVSKRAIKRNTKGAKMEEEGGEDTGLEEDSRDGQDETVILQSSQDRDTVDTGVPDGMEAQDLSVPCLGKADTDKQSLDAFDDSKEYVAAQLGQLPAQLLKHAVNEDVFKNTLEASMSDLKVTMAGEEAPLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEEEEEQEEEQEEEGDLALASSSKSESSSTRCQWSEADALLAVVKREPAEAPGGGGGTQHWRKRKRRRKHQAEAEALGTGGGTWMNREPVGLEEPVEQSSTAAQLPEATSQELVRAPTAAPSPEPRDSKDDVKKFAFDACNDVPAAPKESSASEGADQKMSFVKEEQDIKPVIKDEKGRASCSSGRNLWVSGLSSSTRAADLKSLFSKHGKVIGAKVVTNARSPGARCYGFVTMSMSDEATKCINHLHRTELHGRMISVEKAKNEPSEKKSADRRACDQKEKVPGPDRPHPVKIKMEKTVIKKEEKLERKEEKGPEDIKKEKDQDELPPGTASHSRVTKSGSRCTERTVVMDKSKGEPVISVKATSRSKDRSSKSQDRKSEGREKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLDAFQERREKARLQRERLQLQCQRQRLERERLERERLERERMRVERERRKEQQRIMREREELRRQQEQLRAEQERRALRRAYNLDARRDDGYWPEGKRAAMEDRYRDFPRPDHRFHDFDHRERGHYQEHVIDRRDGSRPRMEERDGPYYPDDQHSHGRPLEHHGWDARDGWHGYSSDKKLNEGLGLPPPPRVSREWAEHSSQLEEQQVPVWHNAVDTNMTGHEHIRWRGAERGLTGPGHGHVAAGRGGMAGQGSFAHGEHSQGHIMPSGRLEGGGVASQDQGGRIPNSHPHPHFTRRY

Target ORF information:

RefSeq Version	NM_001303144.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus scaffold attachment factor B2 (Safb2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303144.1

ORF Insert Sequence:

ATGGCAGAAC CTGTGACCGG GTCGGGCGAC CCGGCTTTTA GTCCGGTCGC TTCGGATAGT 
GGGATGCGGC GGCTCAGCGA CCTGCGGGTG ATCGACCTGA GGGCGGAGCT GAAGAAGCGG 
AACCTGGATA CAGGAGGCAA CAAGAGTGTG TTGATGGAGC GGCTGAAGAA GGCATTTAAA 
GAGGAAGGAC AAGAACCTGA GGAAGTCGGT ATCAGTTGGG GAGCTGTAAG CAAGAGGGCT 
ATAAAGAGAA ACACCAAAGG GGCCAAGATG GAGGAGGAGG GCGGTGAGGA CACCGGCCTG 
GAGGAAGATT CCAGAGATGG GCAGGATGAG ACTGTGATTC TTCAGAGTTC ACAAGACAGG 
GACACTGTGG ATACAGGTGT GCCAGATGGG ATGGAGGCTC AGGACCTCAG TGTGCCCTGC 
CTGGGGAAGG CCGACACCGA CAAACAGTCT CTTGATGCCT TTGATGACAG TAAAGAGTAC 
GTGGCCGCGC AGCTGGGACA GCTTCCAGCT CAGCTCCTGA AGCATGCTGT GAATGAGGAT 
GTCTTCAAGA ACACTCTGGA AGCTTCCATG TCAGACCTTA AAGTAACTAT GGCTGGTGAA 
GAAGCCCCGT TGGAACCAGA AAATGAGAAA ATACTCGACA TTTTGGGGGA AACTTGTAAA 
TCTGAGCCAG TAAAAGAAGA AGGTTCGGAG CTGGAGCAGC CCTTTGCCCA GGCCACGAGT 
AGCGTGGGGC CAGACAGGAA GCTGGCGGAG GAAGAGGACC TATTTGAGAG CTGCGGCCAC 
CCGGAAGAGG AAGAAGAAGA GGAGGAAGAA GAGGAGCAGG AAGAGGAGCA GGAGGAGGAG 
GGAGATTTAG CTTTGGCCAG CAGCAGCAAG TCTGAGTCTT CAAGCACTCG ATGTCAGTGG 
AGCGAGGCAG ACGCCCTGTT AGCAGTAGTG AAAAGGGAGC CGGCAGAGGC GCCTGGTGGA 
GGCGGAGGTA CTCAGCACTG GCGGAAGCGA AAGCGAAGGC GGAAGCATCA GGCAGAGGCA 
GAAGCTCTGG GCACGGGTGG AGGTACCTGG ATGAACCGCG AGCCTGTAGG GCTAGAGGAG 
CCAGTTGAAC AGAGTAGCAC GGCTGCCCAG CTCCCGGAGG CCACCAGCCA GGAGCTGGTG 
CGAGCGCCCA CGGCAGCCCC GAGCCCTGAG CCCCGAGATA GCAAAGACGA CGTGAAGAAG 
TTTGCTTTTG ACGCTTGTAA TGACGTCCCT GCGGCTCCTA AAGAGTCCTC AGCCAGTGAG 
GGTGCTGATC AGAAAATGAG CTTTGTTAAG GAAGAACAGG ATATAAAGCC AGTCATTAAA 
GACGAGAAAG GCCGTGCCAG CTGTAGCTCA GGAAGGAACC TGTGGGTCAG TGGACTGTCC 
TCCAGCACAC GTGCTGCTGA TCTCAAGAGC CTCTTCAGCA AGCATGGGAA GGTCATTGGA 
GCCAAGGTGG TTACCAATGC CCGCAGTCCT GGAGCTCGAT GCTATGGATT TGTGACCATG 
TCCATGTCAG ATGAGGCCAC CAAATGCATC AACCACCTGC ACAGAACAGA ACTGCATGGA 
AGGATGATCT CTGTGGAGAA GGCCAAAAAT GAGCCCTCTG AGAAGAAGTC AGCAGACAGG 
AGAGCTTGTG ACCAAAAGGA GAAGGTGCCA GGGCCAGACA GGCCTCACCC TGTGAAGATC 
AAGATGGAGA AAACTGTGAT CAAAAAGGAA GAGAAACTGG AAAGAAAGGA AGAGAAAGGG 
CCAGAGGACA TTAAGAAGGA GAAGGATCAA GATGAGCTTC CACCAGGAAC CGCCAGTCAT 
TCTCGAGTAA CCAAATCAGG AAGCAGATGC ACGGAGCGTA CAGTCGTGAT GGACAAGTCC 
AAGGGCGAGC CCGTCATCAG TGTGAAGGCC ACAAGCAGGT CAAAGGACAG AAGCTCCAAA 
AGTCAAGACC GAAAGTCAGA GGGCAGGGAG AAGAGAGACA TATTGTCATT TGACAAGATC 
AAGGAGCAGC GGGAGCGGGA GCGCCAGAGG CAGAGGGAGC GTGAAATCCG GGAGACCGAG 
CGGCGACGGG AGCGGGAGCA GCGAGAGCGG GAGCAGCGTC TGGATGCCTT CCAGGAGCGG 
CGGGAGAAGG CTCGTTTGCA GCGAGAACGG CTGCAGCTCC AATGCCAGCG GCAGCGTCTA 
GAAAGGGAGC GGCTGGAGAG GGAGAGACTG GAGAGGGAGC GCATGCGAGT GGAGCGTGAA 
AGGCGCAAGG AACAGCAGCG CATTATGCGT GAGCGTGAGG AGCTGCGACG GCAGCAAGAG 
CAGCTGCGGG CTGAGCAGGA ACGGCGAGCA TTGCGCAGAG CCTACAACCT GGATGCTAGG 
AGAGATGATG GCTACTGGCC AGAAGGGAAG CGTGCAGCCA TGGAAGACAG ATATCGAGAC 
TTTCCAAGGC CAGATCACCG TTTCCATGAC TTCGATCACC GGGAACGGGG TCATTACCAG 
GAGCATGTTA TAGACAGGAG GGATGGGTCC AGACCCAGAA TGGAAGAGCG GGATGGGCCG 
TACTACCCAG ATGACCAGCA CAGCCATGGA AGGCCTCTGG AGCACCATGG TTGGGACGCC 
CGAGACGGCT GGCATGGCTA CAGCTCTGAC AAGAAGTTGA ATGAAGGCCT AGGGCTACCC 
CCTCCCCCCA GGGTCAGCCG AGAATGGGCA GAGCACAGCT CACAGTTGGA GGAGCAGCAG 
GTTCCTGTCT GGCACAACGC TGTGGACACA AACATGACGG GCCATGAACA CATACGGTGG 
CGAGGTGCTG AGCGGGGCCT TACAGGACCT GGGCATGGGC ATGTGGCAGC AGGCCGGGGT 
GGCATGGCTG GGCAAGGCAG CTTTGCACAC GGTGAACATT CCCAGGGCCA TATTATGCCT 
AGTGGTAGAC TGGAAGGTGG TGGCGTGGCC AGCCAGGACC AGGGTGGCCG AATTCCCAAC 
TCCCACCCTC ACCCCCACTT CACCCGCCGC TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1.
Disease models & mechanisms8(9)1121-7(2015 Sep)
Jiang S,Katz TA,Garee JP,DeMayo FJ,Lee AV,Oesterreich S

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.
The FEBS journal276(18)5212-27(2009 Sep)
Tsianou D,Nikolakaki E,Tzitzira A,Bonanou S,Giannakouros T,Georgatsou E

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.
Journal of proteome research7(8)3475-80(2008 Aug)
Kang D,Oh S,Ahn SM,Lee BH,Moon MH