Cacng1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cacng1
Entrez Gene ID	29658
Full Name	calcium voltage-gated channel auxiliary subunit gamma 1
Synonyms	Cacng
General protein information	Preferred Names calcium voltage-gated channel auxiliary subunit gamma 1 Names voltage-dependent calcium channel gamma-1 subunit calcium channel, voltage-dependent, gamma subunit 1 dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1
Summary	calcium channel subunit involved in inactivation of calcium channel current [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019255.1	NP_062128.1	voltage-dependent calcium channel gamma-1 subunit

Pathways from BioSystems

Homologies

Homo sapiens (human)	CACNG1	NP_000718.1
Gallus gallus (chicken)	CACNG1	NP_001264935.1
Danio rerio (zebrafish)	cacng1	NP_999849.1
Pan troglodytes (chimpanzee)	CACNG1	XP_001163880.1
Xenopus tropicalis (tropical clawed frog)	cacng1	NP_001011035.1
Gallus gallus (chicken)	LOC100859535	XP_003642389.1
Danio rerio (zebrafish)	LOC571193	XP_699850.2
Canis lupus familiaris (dog)	CACNG1	XP_853551.1
Bos taurus (cattle)	CACNG1	NP_001073806.1
Mus musculus (house mouse)	Cacng1	NP_031608.1
Rattus norvegicus (Norway rat)	Cacng1	NP_062128.1

Gene Ontology
Bibliography

Related articles in PubMed

Altered inactivation of Ca2+ current and Ca2+ release in mouse muscle fibers deficient in the DHP receptor gamma1 subunit.
Ursu D, Schuhmeier RP, Freichel M, Flockerzi V, Melzer W
The Journal of general physiology124(5)605-18(2004 Nov)

Calcium channel gamma subunits provide insights into the evolution of this gene family.
Chu PJ, Robertson HM, Best PM
Gene280(1-2)37-48(2001 Dec)

Absence of the gamma subunit of the skeletal muscle dihydropyridine receptor increases L-type Ca2+ currents and alters channel inactivation properties.
Freise D, Held B, Wissenbach U, Pfeifer A, Trost C, Himmerkus N, Schweig U, Freichel M, Biel M, Hofmann F, Hoth M, Flockerzi V
The Journal of biological chemistry275(19)14476-81(2000 May)

Identification and functional characterization of a calcium channel gamma subunit.
Eberst R, Dai S, Klugbauer N, Hofmann F
Pflugers Archiv : European journal of physiology433(5)633-7(1997 Mar)

Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility.
Iles DE, Segers B, Sengers RC, Monsieurs K, Heytens L, Halsall PJ, Hopkins PM, Ellis FR, Hall-Curran JL, Stewart AD
Human molecular genetics2(7)863-8(1993 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cacng1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cacng1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04179	NM_019255.1 Latest version!	Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 1 (Cacng1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cacng1 ( NM_019255.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062128.1 Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 1 (Cacng1), mRNA.

Price & Availability↑

CloneID	ORa04179
Clone ID Related Accession (Same CDS sequence)	NM_019255.1
Accession Version	NM_019255.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	voltage-dependent calcium channel gamma-1 subunit
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y09453.1. ##Evidence-Data-START## Transcript exon combination :: Y09453.1, FQ215004.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689600, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGTCACAGA CCAAAACAGC GAAGGTTCGC GTGACCCTCT TCTTCATCCT GGCGGGTGGA 
GTGCTCGCCA TGGTGGCCGT GGTGACCGAC CACTGGGCCG TGCTGAGTCC ACACCTGGAG 
CACCACAATG AGACGTGCGT GGCAGCCCAC TTCGGCCTTT GGAGGATCTG CACCACTTGG 
GTTGCCATGC ACAACCAAGA CAAGAACTGT GACGGCACCA TACCAGCGGG GGAAAAGAAT 
TGCTCCTACT TCAGGCACTT CAACCCAGGA GAGAGCTCGG AAATCTTTGA ATTCACCACT 
CAGAAGGAGT ACAGCATCTC GGCAGCGGCC ATCGCTATCT TCAGCCTTGG CTTCATCATC 
ATAGGCTCCA TCTGTGCCTT TCTGTCCTTC GGGAATAAGC GTGATTACCT GCTAAGGCCG 
GCATCCATGT TTTATGCCTT TGCAGGGCTC TGCCTCATCG TGTCGGTGGA GGTCATGAGG 
CAGTCGGTGA AGCGTATGAT TGACAGCGAG GACACGGTCT GGATTGAGTA CTATTATTCG 
TGGTCTTTCG CCTGCGCGTG TGCCGGCTTC ACTTTGCTCT TCCTCGGTGG GCTGTTTCTC 
CTGCTGTTCT CCCTGCCTCG GATGCCCCAG AACCCCTGGG AATCCTGCAT GGACACTGAG 
TCAGAGCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062128.1
CDS	11..682
Translation	MSQTKTAKVRVTLFFILAGGVLAMVAVVTDHWAVLSPHLEHHNETCVAAHFGLWRICTTWVAMHNQDKNCDGTIPAGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIIIGSICAFLSFGNKRDYLLRPASMFYAFAGLCLIVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAGFTLLFLGGLFLLLFSLPRMPQNPWESCMDTESEH

Target ORF information:

RefSeq Version	NM_019255.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 1 (Cacng1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019255.1

ORF Insert Sequence:

ATGTCACAGA CCAAAACAGC GAAGGTTCGC GTGACCCTCT TCTTCATCCT GGCGGGTGGA 
GTGCTCGCCA TGGTGGCCGT GGTGACCGAC CACTGGGCCG TGCTGAGTCC ACACCTGGAG 
CACCACAATG AGACGTGCGT GGCAGCCCAC TTCGGCCTTT GGAGGATCTG CACCACTTGG 
GTTGCCATGC ACAACCAAGA CAAGAACTGT GACGGCACCA TACCAGCGGG GGAAAAGAAT 
TGCTCCTACT TCAGGCACTT CAACCCAGGA GAGAGCTCGG AAATCTTTGA ATTCACCACT 
CAGAAGGAGT ACAGCATCTC GGCAGCGGCC ATCGCTATCT TCAGCCTTGG CTTCATCATC 
ATAGGCTCCA TCTGTGCCTT TCTGTCCTTC GGGAATAAGC GTGATTACCT GCTAAGGCCG 
GCATCCATGT TTTATGCCTT TGCAGGGCTC TGCCTCATCG TGTCGGTGGA GGTCATGAGG 
CAGTCGGTGA AGCGTATGAT TGACAGCGAG GACACGGTCT GGATTGAGTA CTATTATTCG 
TGGTCTTTCG CCTGCGCGTG TGCCGGCTTC ACTTTGCTCT TCCTCGGTGG GCTGTTTCTC 
CTGCTGTTCT CCCTGCCTCG GATGCCCCAG AACCCCTGGG AATCCTGCAT GGACACTGAG 
TCAGAGCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Altered inactivation of Ca2+ current and Ca2+ release in mouse muscle fibers deficient in the DHP receptor gamma1 subunit.
The Journal of general physiology124(5)605-18(2004 Nov)
Ursu D,Schuhmeier RP,Freichel M,Flockerzi V,Melzer W

Calcium channel gamma subunits provide insights into the evolution of this gene family.
Gene280(1-2)37-48(2001 Dec)
Chu PJ,Robertson HM,Best PM

Absence of the gamma subunit of the skeletal muscle dihydropyridine receptor increases L-type Ca2+ currents and alters channel inactivation properties.
The Journal of biological chemistry275(19)14476-81(2000 May)
Freise D,Held B,Wissenbach U,Pfeifer A,Trost C,Himmerkus N,Schweig U,Freichel M,Biel M,Hofmann F,Hoth M,Flockerzi V

Identification and functional characterization of a calcium channel gamma subunit.
Pflugers Archiv : European journal of physiology433(5)633-7(1997 Mar)
Eberst R,Dai S,Klugbauer N,Hofmann F

Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility.
Human molecular genetics2(7)863-8(1993 Jul)
Iles DE,Segers B,Sengers RC,Monsieurs K,Heytens L,Halsall PJ,Hopkins PM,Ellis FR,Hall-Curran JL,Stewart AD