Tnnc2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tnnc2
Entrez Gene ID	296369
Full Name	troponin C2, fast skeletal type
General protein information	Preferred Names troponin C2, fast skeletal type Names troponin C, skeletal muscle skeletal troponin C troponin C type 2 (fast)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q42

mRNA and Protein(s)

mRNA	Protein	Name
NM_001037351.2	NP_001032428.1	troponin C, skeletal muscle

Pathways from BioSystems

Homologies

	TNNC2	XP_001108623.1
Gallus gallus (chicken)	TNNC2	NP_990781.1
Danio rerio (zebrafish)	tnnc2	NP_571638.1
Canis lupus familiaris (dog)	TNNC2	XP_543023.2
Homo sapiens (human)	TNNC2	NP_003270.1
Bos taurus (cattle)	TNNC2	NP_001069841.1
Mus musculus (house mouse)	Tnnc2	NP_033420.1
Pan troglodytes (chimpanzee)	TNNC2	XP_001157246.1
Rattus norvegicus (Norway rat)	Tnnc2	NP_001032428.1
Xenopus tropicalis (tropical clawed frog)	tnnc2	NP_988957.1

Gene Ontology
Bibliography

Related articles in PubMed

Calcium, troponin, calmodulin, S100 proteins: from myocardial basics to new therapeutic strategies.
Schaub MC, Heizmann CW
Biochemical and biophysical research communications369(1)247-64(2008 Apr)

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function.
Robinson P, Lipscomb S, Preston LC, Altin E, Watkins H, Ashley CC, Redwood CS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology21(3)896-905(2007 Mar)

Differences in myofilament calcium sensitivity in rat psoas fibers reconstituted with troponin T isoforms containing the alpha- and beta-exons.
Gallon CE, Tschirgi ML, Chandra M
Archives of biochemistry and biophysics456(2)127-34(2006 Dec)

Cloning and characterization of cDNA sequences corresponding to myosin light chains 1, 2, and 3, troponin-C, troponin-T, alpha-tropomyosin, and alpha-actin.
Garfinkel LI, Periasamy M, Nadal-Ginard B
The Journal of biological chemistry257(18)11078-86(1982 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tnnc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tnnc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09279	NM_001037351.2 Latest version!	Rattus norvegicus troponin C2, fast skeletal type (Tnnc2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tnnc2 ( NM_001037351.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001032428.1 Rattus norvegicus troponin C2, fast skeletal type (Tnnc2), mRNA.

Price & Availability↑

CloneID	ORa09279
Clone ID Related Accession (Same CDS sequence)	NM_001037351.2
Accession Version	NM_001037351.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 483bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-31
Organism	Rattus norvegicus(Norway rat)
Product	troponin C, skeletal muscle
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FQ217974.1 and FQ218048.1. On Mar 2, 2016 this sequence version replaced NM_001037351.1. ##Evidence-Data-START## Transcript exon combination :: FQ217974.1, FQ218048.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689600, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGACGGACC AACAGGCTGA GGCCAGGTCC TACCTCAGCG AGGAGATGAT CGCTGAGTTC 
AAGGCTGCCT TTGACATGTT TGATGCTGAT GGTGGTGGGG ACATCAGCGT TAAAGAGCTG 
GGTACCGTGA TGAGGATGCT AGGGCAGACA CCCACCAAAG AGGAACTGGA CGCCATCATC 
GAGGAGGTGG ACGAGGATGG CAGCGGTACC ATCGACTTTG AAGAGTTCTT GGTCATGATG 
GTGCGCCAGA TGAAAGAGGA TGCGAAAGGG AAGAGCGAAG AGGAACTGGC TGAGTGTTTC 
CGCATCTTTG ACAGGAACGC AGACGGTTAC ATTGATGCCG AGGAGCTGGC TGAGATTTTC 
CGGGCTTCTG GGGAGCATGT GACAGACGAG GAGATCGAAT CCCTGATGAA GGATGGTGAT 
AAGAACAACG ATGGCCGCAT TGACTTCGAC GAGTTTCTGA AGATGATGGA GGGCGTTCAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032428.1
CDS	94..576
Translation	MTDQQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDAEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGVQ

Target ORF information:

RefSeq Version	NM_001037351.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus troponin C2, fast skeletal type (Tnnc2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037351.2

ORF Insert Sequence:

ATGACGGACC AACAGGCTGA GGCCAGGTCC TACCTCAGCG AGGAGATGAT CGCTGAGTTC 
AAGGCTGCCT TTGACATGTT TGATGCTGAT GGTGGTGGGG ACATCAGCGT TAAAGAGCTG 
GGTACCGTGA TGAGGATGCT AGGGCAGACA CCCACCAAAG AGGAACTGGA CGCCATCATC 
GAGGAGGTGG ACGAGGATGG CAGCGGTACC ATCGACTTTG AAGAGTTCTT GGTCATGATG 
GTGCGCCAGA TGAAAGAGGA TGCGAAAGGG AAGAGCGAAG AGGAACTGGC TGAGTGTTTC 
CGCATCTTTG ACAGGAACGC AGACGGTTAC ATTGATGCCG AGGAGCTGGC TGAGATTTTC 
CGGGCTTCTG GGGAGCATGT GACAGACGAG GAGATCGAAT CCCTGATGAA GGATGGTGAT 
AAGAACAACG ATGGCCGCAT TGACTTCGAC GAGTTTCTGA AGATGATGGA GGGCGTTCAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Calcium, troponin, calmodulin, S100 proteins: from myocardial basics to new therapeutic strategies.
Biochemical and biophysical research communications369(1)247-64(2008 Apr)
Schaub MC,Heizmann CW

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology21(3)896-905(2007 Mar)
Robinson P,Lipscomb S,Preston LC,Altin E,Watkins H,Ashley CC,Redwood CS

Differences in myofilament calcium sensitivity in rat psoas fibers reconstituted with troponin T isoforms containing the alpha- and beta-exons.
Archives of biochemistry and biophysics456(2)127-34(2006 Dec)
Gallon CE,Tschirgi ML,Chandra M

Cloning and characterization of cDNA sequences corresponding to myosin light chains 1, 2, and 3, troponin-C, troponin-T, alpha-tropomyosin, and alpha-actin.
The Journal of biological chemistry257(18)11078-86(1982 Sep)
Garfinkel LI,Periasamy M,Nadal-Ginard B