Jtb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Jtb
Entrez Gene ID	29439
Full Name	jumping translocation breakpoint
General protein information	Preferred Names jumping translocation breakpoint Names protein JTB protein JTB-like
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	human homologue involved in jumping translocation in which partial chromosomal duplication occurs at the end of the chromosomes; observed in leukemic patients [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019213.2	NP_062086.1	protein JTB precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Jtb	NP_062086.1
	LOC718537	XP_001111373.2
Mus musculus (house mouse)	Jtb	NP_996807.1
Homo sapiens (human)	JTB	NP_006685.1
Pan troglodytes (chimpanzee)	JTB	XP_001149478.1
Canis lupus familiaris (dog)	JTB	XP_855136.1
Bos taurus (cattle)	JTB	NP_001093830.1

Gene Ontology
Bibliography

Related articles in PubMed

PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins.
Platica M, Ionescu A, Ivan E, Holland JF, Mandeli J, Platica O
International journal of oncology38(3)777-85(2011 Mar)

Characterization of Jumping translocation breakpoint (JTB) gene product isolated as a TGF-beta1-inducible clone involved in regulation of mitochondrial function, cell growth and cell death.
Kanome T, Itoh N, Ishikawa F, Mori K, Kim-Kaneyama JR, Nose K, Shibanuma M
Oncogene26(41)5991-6001(2007 Sep)

JTB: a novel membrane protein gene at 1q21 rearranged in a jumping translocation.
Hatakeyama S, Osawa M, Omine M, Ishikawa F
Oncogene18(12)2085-90(1999 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Jtb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Jtb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04050	NM_019213.2 Latest version!	Rattus norvegicus jumping translocation breakpoint (Jtb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Jtb ( NM_019213.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062086.1 Rattus norvegicus jumping translocation breakpoint (Jtb), mRNA.

Price & Availability↑

CloneID	ORa04050
Clone ID Related Accession (Same CDS sequence)	NM_019213.2
Accession Version	NM_019213.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	protein JTB precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC062090.1. On Oct 17, 2004 this sequence version replaced NM_019213.1. ##Evidence-Data-START## Transcript exon combination :: BC062090.1, AB016489.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCTCGTGG GCGCGGGGAG GCGTGGCCTC CCCCGGGGCG GCCACCTCTG TTGGTTGCTG 
TGCGCTTTCA CCTTAAAGCT CTGCGAAGCA GAGGCCCCGG TGCGCGAGGA GAAGCTATCA 
GTGAGCACAT CAACTTCACC ATGTTGGTTG GTAGAAGAGT TTGTGGTGAC CGAAGAGTGT 
ACTCCGTGTT CTAACTTCCA GATTAAAACG ACACCTGAGT GTGGTTCTAC AGGGTATGTG 
GAGAAAATCA CATGCAGCTC ATCTAAGAGG AATGAATTCA AAAGCTGCCG TTCAGCTCTT 
CTGGAACAAC ACTTATTTTG GAAGTTTGAA GGCATCGTGG TGGGGGTAGC TTTAGTCTTC 
GCTTGCCTTG TCATCATTCG TCAGCGACAG CTGGACAGAA AGGCTCTTGA AAAAGTCCGG 
AAGCAAATTG AATCCATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062086.1
CDS	273..713
Translation	MLVGAGRRGLPRGGHLCWLLCAFTLKLCEAEAPVREEKLSVSTSTSPCWLVEEFVVTEECTPCSNFQIKTTPECGSTGYVEKITCSSSKRNEFKSCRSALLEQHLFWKFEGIVVGVALVFACLVIIRQRQLDRKALEKVRKQIESI

Target ORF information:

RefSeq Version	NM_019213.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus jumping translocation breakpoint (Jtb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019213.2

ORF Insert Sequence:

ATGCTCGTGG GCGCGGGGAG GCGTGGCCTC CCCCGGGGCG GCCACCTCTG TTGGTTGCTG 
TGCGCTTTCA CCTTAAAGCT CTGCGAAGCA GAGGCCCCGG TGCGCGAGGA GAAGCTATCA 
GTGAGCACAT CAACTTCACC ATGTTGGTTG GTAGAAGAGT TTGTGGTGAC CGAAGAGTGT 
ACTCCGTGTT CTAACTTCCA GATTAAAACG ACACCTGAGT GTGGTTCTAC AGGGTATGTG 
GAGAAAATCA CATGCAGCTC ATCTAAGAGG AATGAATTCA AAAGCTGCCG TTCAGCTCTT 
CTGGAACAAC ACTTATTTTG GAAGTTTGAA GGCATCGTGG TGGGGGTAGC TTTAGTCTTC 
GCTTGCCTTG TCATCATTCG TCAGCGACAG CTGGACAGAA AGGCTCTTGA AAAAGTCCGG 
AAGCAAATTG AATCCATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins.
International journal of oncology38(3)777-85(2011 Mar)
Platica M,Ionescu A,Ivan E,Holland JF,Mandeli J,Platica O

Characterization of Jumping translocation breakpoint (JTB) gene product isolated as a TGF-beta1-inducible clone involved in regulation of mitochondrial function, cell growth and cell death.
Oncogene26(41)5991-6001(2007 Sep)
Kanome T,Itoh N,Ishikawa F,Mori K,Kim-Kaneyama JR,Nose K,Shibanuma M

JTB: a novel membrane protein gene at 1q21 rearranged in a jumping translocation.
Oncogene18(12)2085-90(1999 Mar)
Hatakeyama S,Osawa M,Omine M,Ishikawa F