Eif3c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif3c
Entrez Gene ID	293484
Full Name	eukaryotic translation initiation factor 3, subunit C
Synonyms	Eif3s8
General protein information	Preferred Names eukaryotic translation initiation factor 3, subunit C Names eukaryotic translation initiation factor 3 subunit C eIF3 p110 eukaryotic translation initiation factor 3 subunit 8 eukaryotic translation initiation factor 3, subunit 8, 110kDa
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q36

mRNA and Protein(s)

mRNA	Protein	Name
XM_006230226.2	XP_006230288.1	eukaryotic translation initiation factor 3 subunit C isoform X1
NM_001100662.1	NP_001094132.1	eukaryotic translation initiation factor 3 subunit C

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	EIF3C	XP_536923.2
Bos taurus (cattle)	EIF3CL	NP_001029790.1
Mus musculus (house mouse)	Eif3c	NP_666312.1
Rattus norvegicus (Norway rat)	Eif3c	NP_001094132.1
Kluyveromyces lactis	KLLA0F03014g	XP_455216.1
Schizosaccharomyces pombe (fission yeast)	tif33	NP_593828.2
Arabidopsis thaliana (thale cress)	EIF3C	NP_001190102.1
Xenopus tropicalis (tropical clawed frog)	eif3c	NP_989413.1
Homo sapiens (human)	EIF3C	NP_003743.1
Saccharomyces cerevisiae (baker's yeast)	NIP1	NP_014040.1
Danio rerio (zebrafish)	eif3c	NP_998628.1
Drosophila melanogaster (fruit fly)	eIF3-S8	NP_611242.1
Eremothecium gossypii	AGOS_AGL344C	NP_986323.1
Arabidopsis thaliana (thale cress)	TIF3C2	NP_188926.4
Oryza sativa (rice)	Os07g0124500	NP_001058804.1
Magnaporthe oryzae (rice blast fungus)	MGG_16895	XP_003712797.1
	LOC705696	XP_002808338.1
Anopheles gambiae (African malaria mosquito)	EIF3C_ANOGA	XP_318103.3
Caenorhabditis elegans (roundworm)	eif-3.C	NP_492638.1
Neurospora crassa	NCU07831	XP_962952.1

Gene Ontology
Bibliography

Related articles in PubMed

eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.
Lee AS, Kranzusch PJ, Cate JH
Nature522(7554)111-4(2015 Jun)

The scanning mechanism of eukaryotic translation initiation.
Hinnebusch AG
Annual review of biochemistry83779-812(2014)

Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome.
Villa N, Do A, Hershey JW, Fraser CS
The Journal of biological chemistry288(46)32932-40(2013 Nov)

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.
Zeng L, Wan Y, Li D, Wu J, Shao M, Chen J, Hui L, Ji H, Zhu X
The Journal of biological chemistry288(42)30087-93(2013 Oct)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eif3c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif3c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04579	NM_001100662.1 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 3, subunit C (Eif3c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa04579	XM_006230226.2 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 3, subunit C (Eif3c), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif3c ( NM_001100662.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001094132.1 Rattus norvegicus eukaryotic translation initiation factor 3, subunit C (Eif3c), mRNA.

Price & Availability↑

CloneID	ORa04579
Clone ID Related Accession (Same CDS sequence)	XM_006230226.2 , NM_001100662.1
Accession Version	NM_001100662.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 3 subunit C
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC169011.1. On or before Sep 10, 2008 this sequence version replaced XM_001079906.1, XM_215080.4. ##Evidence-Data-START## Transcript exon combination :: BC169011.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCCCGGT TTTTCACCAC CGGCTCGGAC AGTGAGTCGG AGTCGTCCCT GTCCGGGGAG 
GAGCTCGTCA CCAAACCAGT CTCCGGGAAC TATGGCAAAC AGCCTTTGTT ACTGAGCGAG 
GATGAAGAGG ATACAAAGAG AGTTGTTCGA AGTGCCAAGG ACAAGAGGTT TGAGGAGCTG 
ACCAACCTTA TACGAACCAT CCGTAATGCC ATGAAGATTC GAGATGTCAC CAAGTGTCTA 
GAAGAGTTTG AACTCCTGGG AAAAGCCTAT GGGAAAGCCA AGAGTATTGT GGATAAGGAG 
GGTGTCCCCC GATTCTATGT CCGGATATTG GCTGACCTGG AGGACTATCT TAATGAGCTT 
TGGGAAGATA AGGAAGGGAA AAAGAAGATG AATAAAAACA ATGCCAAGGC TCTGAGTACA 
TTGCGCCAGA AGATCCGAAA ATACAACCGA GATTTTGAGT CTCACATCAC CAACTATAAG 
CAGAACCCTG AACAATCTGC AGATGAAGAT GCAGAAAAGA ATGAGGAAGA CTCAGAAGGC 
TCTTCAGATG AGGATGAAGA TGACGATGGA GTCAGTGGTA CAGCCTTCTT GAAGAAGAAA 
CCAGACTCTT CTGGGGAGAG TCGAAAGTTC CACAAAAAGA TGGAGGATGA TGATGAGGAC 
TCTGAAGATT CTGAGGATGA AGAATGGGAC ACCAGTTCCA CATCTTCTGA TTCAGACTCC 
GAAGAAGAAG AAGGAAAACA AACTGTTCTG GCCTCAAAGT TCCTTAAAAA GGCACCCACC 
ACAGAGGAGG ACAAAAAGGC AGCTGAAAAG AAACGGGAAG ACAAAGCCAA GAAGAAGCAC 
GATAGGAAGT CTAAGCGCAT GGATGAGGAA GAGGAGGACA ATGAAGGCGG GGAGTGGGAA 
CGGGTCCGAG GCGGCGTACC ACTTGTTAAG GAGAAACCAA AAATGTTTGC CAAGGGAACA 
GAGATCACTC ATGCTGTTGT CATCAAGAAG CTGAATGAGA TTCTACAGGT CAGAGGCAAG 
AAGGGAACAG ACCGTGCTAC CCAGATTGAA TTGCTCCAGC TGCTGGTTCA GATTGCTTCT 
GAAAACAACC TGGGGGTGGG TGTCATTGTC AAGATCAAGT TCAATATCAT TGCCTCTCTC 
TACGATTACA ACCCTAACCT GGCCACGTAC ATGAAGCCAG AGATGTGGCA GATGTGCCTG 
GACTGTATCA ATGAGTTGAT GGATACCTTG GTTGCACATT CCAACATCTT TGTTGGAGAG 
AACATTTTGG AAGAGAGTGA GAACTTACAC AATTTTGATC AGCCACTGCG TGTACGAGGC 
TGCATCCTAA CTCTGGTGGA GCGAATGGAT GAAGAATTTA CCAAAATAAT GCAAAATACT 
GATCCTCACT CCCAAGAGTA TGTGGAACAT CTGAAGGATG AGGCACAAGT ATGTGCCATC 
ATTGAGCGTG TACAGCGCTA CCTGGAGGAG AAAGGTACCA CTGAGGAGAT CTGCCAGATC 
TACTTGAGGC GCATCCTGCA CACTTACTAC AAGTTTGATT ACAAGGCCCA TCAGCGTCAG 
CTTACTCCTC CGGAAGGGTC CTCAAAGTCT GAGCAAGACC AGGCAGAAAA TGAGGGTGAG 
GACTCAGCTG TGCTAATGGA AAGACTGTGC AAATACATCT ATGCCAAGGA CCGTACAGAC 
CGCATCCGTA CCTGTGCCAT CCTCTGCCAT ATCTACCATC ATGCGCTCCA CTCCCGCTGG 
TATCAGGCCC GTGACCTCAT GCTCATGAGC CACCTACAAG ACAACATCCA GCACGCAGAC 
CCGCCAGTAC AGATCCTGTA TAACCGTACC ATGGTGCAAC TGGGCATCTG TGCTTTCCGC 
CAAGGCCTGA CAAAGGATGC ACACAATGCA CTTCTGGATA TTCAGTCAAG TGGTCGTGCC 
AAGGAGCTTC TGGGCCAGGG TCTGCTGCTG CGCAGCCTCC AGGAGCGCAA CCAGGAACAG 
GAGAAGGTAG AGCGACGCCG GCAGGTGCCC TTTCACCTGC ACATCAACCT GGAACTGCTG 
GAGTGTGTGT ATCTGGTGTC TGCTATGCTC CTGGAGATCC CCTACATGGC TGCCCATGAG 
AGTGATGCCC GCCGACGCAT GATCAGCAAG CAGTTCCATC ACCAACTGCG GGTGGGCGAG 
CGGCAGCCCC TGCTAGGTCC TCCTGAGTCA ATGAGGGAGC ATGTGGTTGC TGCCTCCAAG 
GCCATGAAGA TGGGTGACTG GAAGACCTGC CACAGTTTCA TCATTAATGA AAAGATGAAT 
GGGAAAGTGT GGGACCTTTT CCCTGAGGCT GACAAAGTTC GCACCATGCT AGTTCGGAAG 
ATCCAGGAAG AGTCTCTGAG GACCTACCTT TTTACCTATA GCAGTGTCTA TGACTCAATC 
AGTATGGAGA CACTCTCAGA TATGTTTGAG CTGGATCTGC CCACTGTTCA CTCCATCATC 
AGCAAGATGA TCATTAATGA AGAATTGATG GCTTCCCTGG ACCAGCCAAC GCAGACGGTA 
GTGATGCACC GTACTGAGCC CACTGCCCAA CAGAACTTGG CTCTGCAGCT GGCTGAGAAG 
CTTGGCAGCC TAGTGGAGAA TAATGAACGT GTGTTTGACC ATAAGCAAGG AACCTATGGC 
GGCTATTTCC GAGACCAAAA GGATGGCTAC CGAAAAAATG AAGGCTATAT GCGCCGTGGT 
GGCTACCGCC AGCAGCAGTC TCAGACAGCT TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094132.1
CDS	212..2947
Translation	MSRFFTTGSDSESESSLSGEELVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYVRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITNYKQNPEQSADEDAEKNEEDSEGSSDEDEDDDGVSGTAFLKKKPDSSGESRKFHKKMEDDDEDSEDSEDEEWDTSSTSSDSDSEEEEGKQTVLASKFLKKAPTTEEDKKAAEKKREDKAKKKHDRKSKRMDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQVRGKKGTDRATQIELLQLLVQIASENNLGVGVIVKIKFNIIASLYDYNPNLATYMKPEMWQMCLDCINELMDTLVAHSNIFVGENILEESENLHNFDQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEICQIYLRRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMRRGGYRQQQSQTAY

Target ORF information:

RefSeq Version	NM_001100662.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 3, subunit C (Eif3c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100662.1

ORF Insert Sequence:

ATGTCCCGGT TTTTCACCAC CGGCTCGGAC AGTGAGTCGG AGTCGTCCCT GTCCGGGGAG 
GAGCTCGTCA CCAAACCAGT CTCCGGGAAC TATGGCAAAC AGCCTTTGTT ACTGAGCGAG 
GATGAAGAGG ATACAAAGAG AGTTGTTCGA AGTGCCAAGG ACAAGAGGTT TGAGGAGCTG 
ACCAACCTTA TACGAACCAT CCGTAATGCC ATGAAGATTC GAGATGTCAC CAAGTGTCTA 
GAAGAGTTTG AACTCCTGGG AAAAGCCTAT GGGAAAGCCA AGAGTATTGT GGATAAGGAG 
GGTGTCCCCC GATTCTATGT CCGGATATTG GCTGACCTGG AGGACTATCT TAATGAGCTT 
TGGGAAGATA AGGAAGGGAA AAAGAAGATG AATAAAAACA ATGCCAAGGC TCTGAGTACA 
TTGCGCCAGA AGATCCGAAA ATACAACCGA GATTTTGAGT CTCACATCAC CAACTATAAG 
CAGAACCCTG AACAATCTGC AGATGAAGAT GCAGAAAAGA ATGAGGAAGA CTCAGAAGGC 
TCTTCAGATG AGGATGAAGA TGACGATGGA GTCAGTGGTA CAGCCTTCTT GAAGAAGAAA 
CCAGACTCTT CTGGGGAGAG TCGAAAGTTC CACAAAAAGA TGGAGGATGA TGATGAGGAC 
TCTGAAGATT CTGAGGATGA AGAATGGGAC ACCAGTTCCA CATCTTCTGA TTCAGACTCC 
GAAGAAGAAG AAGGAAAACA AACTGTTCTG GCCTCAAAGT TCCTTAAAAA GGCACCCACC 
ACAGAGGAGG ACAAAAAGGC AGCTGAAAAG AAACGGGAAG ACAAAGCCAA GAAGAAGCAC 
GATAGGAAGT CTAAGCGCAT GGATGAGGAA GAGGAGGACA ATGAAGGCGG GGAGTGGGAA 
CGGGTCCGAG GCGGCGTACC ACTTGTTAAG GAGAAACCAA AAATGTTTGC CAAGGGAACA 
GAGATCACTC ATGCTGTTGT CATCAAGAAG CTGAATGAGA TTCTACAGGT CAGAGGCAAG 
AAGGGAACAG ACCGTGCTAC CCAGATTGAA TTGCTCCAGC TGCTGGTTCA GATTGCTTCT 
GAAAACAACC TGGGGGTGGG TGTCATTGTC AAGATCAAGT TCAATATCAT TGCCTCTCTC 
TACGATTACA ACCCTAACCT GGCCACGTAC ATGAAGCCAG AGATGTGGCA GATGTGCCTG 
GACTGTATCA ATGAGTTGAT GGATACCTTG GTTGCACATT CCAACATCTT TGTTGGAGAG 
AACATTTTGG AAGAGAGTGA GAACTTACAC AATTTTGATC AGCCACTGCG TGTACGAGGC 
TGCATCCTAA CTCTGGTGGA GCGAATGGAT GAAGAATTTA CCAAAATAAT GCAAAATACT 
GATCCTCACT CCCAAGAGTA TGTGGAACAT CTGAAGGATG AGGCACAAGT ATGTGCCATC 
ATTGAGCGTG TACAGCGCTA CCTGGAGGAG AAAGGTACCA CTGAGGAGAT CTGCCAGATC 
TACTTGAGGC GCATCCTGCA CACTTACTAC AAGTTTGATT ACAAGGCCCA TCAGCGTCAG 
CTTACTCCTC CGGAAGGGTC CTCAAAGTCT GAGCAAGACC AGGCAGAAAA TGAGGGTGAG 
GACTCAGCTG TGCTAATGGA AAGACTGTGC AAATACATCT ATGCCAAGGA CCGTACAGAC 
CGCATCCGTA CCTGTGCCAT CCTCTGCCAT ATCTACCATC ATGCGCTCCA CTCCCGCTGG 
TATCAGGCCC GTGACCTCAT GCTCATGAGC CACCTACAAG ACAACATCCA GCACGCAGAC 
CCGCCAGTAC AGATCCTGTA TAACCGTACC ATGGTGCAAC TGGGCATCTG TGCTTTCCGC 
CAAGGCCTGA CAAAGGATGC ACACAATGCA CTTCTGGATA TTCAGTCAAG TGGTCGTGCC 
AAGGAGCTTC TGGGCCAGGG TCTGCTGCTG CGCAGCCTCC AGGAGCGCAA CCAGGAACAG 
GAGAAGGTAG AGCGACGCCG GCAGGTGCCC TTTCACCTGC ACATCAACCT GGAACTGCTG 
GAGTGTGTGT ATCTGGTGTC TGCTATGCTC CTGGAGATCC CCTACATGGC TGCCCATGAG 
AGTGATGCCC GCCGACGCAT GATCAGCAAG CAGTTCCATC ACCAACTGCG GGTGGGCGAG 
CGGCAGCCCC TGCTAGGTCC TCCTGAGTCA ATGAGGGAGC ATGTGGTTGC TGCCTCCAAG 
GCCATGAAGA TGGGTGACTG GAAGACCTGC CACAGTTTCA TCATTAATGA AAAGATGAAT 
GGGAAAGTGT GGGACCTTTT CCCTGAGGCT GACAAAGTTC GCACCATGCT AGTTCGGAAG 
ATCCAGGAAG AGTCTCTGAG GACCTACCTT TTTACCTATA GCAGTGTCTA TGACTCAATC 
AGTATGGAGA CACTCTCAGA TATGTTTGAG CTGGATCTGC CCACTGTTCA CTCCATCATC 
AGCAAGATGA TCATTAATGA AGAATTGATG GCTTCCCTGG ACCAGCCAAC GCAGACGGTA 
GTGATGCACC GTACTGAGCC CACTGCCCAA CAGAACTTGG CTCTGCAGCT GGCTGAGAAG 
CTTGGCAGCC TAGTGGAGAA TAATGAACGT GTGTTTGACC ATAAGCAAGG AACCTATGGC 
GGCTATTTCC GAGACCAAAA GGATGGCTAC CGAAAAAATG AAGGCTATAT GCGCCGTGGT 
GGCTACCGCC AGCAGCAGTC TCAGACAGCT TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Eif3c ( XM_006230226.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230288.1 Rattus norvegicus eukaryotic translation initiation factor 3, subunit C (Eif3c), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa04579
Clone ID Related Accession (Same CDS sequence)	XM_006230226.2 , NM_001100662.1
Accession Version	XM_006230226.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 3 subunit C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006230226.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCGGT TTTTCACCAC CGGCTCGGAC AGTGAGTCGG AGTCGTCCCT GTCCGGGGAG 
GAGCTCGTCA CCAAACCAGT CTCCGGGAAC TATGGCAAAC AGCCTTTGTT ACTGAGCGAG 
GATGAAGAGG ATACAAAGAG AGTTGTTCGA AGTGCCAAGG ACAAGAGGTT TGAGGAGCTG 
ACCAACCTTA TACGAACCAT CCGTAATGCC ATGAAGATTC GAGATGTCAC CAAGTGTCTA 
GAAGAGTTTG AACTCCTGGG AAAAGCCTAT GGGAAAGCCA AGAGTATTGT GGATAAGGAG 
GGTGTCCCCC GATTCTATGT CCGGATATTG GCTGACCTGG AGGACTATCT TAATGAGCTT 
TGGGAAGATA AGGAAGGGAA AAAGAAGATG AATAAAAACA ATGCCAAGGC TCTGAGTACA 
TTGCGCCAGA AGATCCGAAA ATACAACCGA GATTTTGAGT CTCACATCAC CAACTATAAG 
CAGAACCCTG AACAATCTGC AGATGAAGAT GCAGAAAAGA ATGAGGAAGA CTCAGAAGGC 
TCTTCAGATG AGGATGAAGA TGACGATGGA GTCAGTGGTA CAGCCTTCTT GAAGAAGAAA 
CCAGACTCTT CTGGGGAGAG TCGAAAGTTC CACAAAAAGA TGGAGGATGA TGATGAGGAC 
TCTGAAGATT CTGAGGATGA AGAATGGGAC ACCAGTTCCA CATCTTCTGA TTCAGACTCC 
GAAGAAGAAG AAGGAAAACA AACTGTTCTG GCCTCAAAGT TCCTTAAAAA GGCACCCACC 
ACAGAGGAGG ACAAAAAGGC AGCTGAAAAG AAACGGGAAG ACAAAGCCAA GAAGAAGCAC 
GATAGGAAGT CTAAGCGCAT GGATGAGGAA GAGGAGGACA ATGAAGGCGG GGAGTGGGAA 
CGGGTCCGAG GCGGCGTACC ACTTGTTAAG GAGAAACCAA AAATGTTTGC CAAGGGAACA 
GAGATCACTC ATGCTGTTGT CATCAAGAAG CTGAATGAGA TTCTACAGGT CAGAGGCAAG 
AAGGGAACAG ACCGTGCTAC CCAGATTGAA TTGCTCCAGC TGCTGGTTCA GATTGCTTCT 
GAAAACAACC TGGGGGTGGG TGTCATTGTC AAGATCAAGT TCAATATCAT TGCCTCTCTC 
TACGATTACA ACCCTAACCT GGCCACGTAC ATGAAGCCAG AGATGTGGCA GATGTGCCTG 
GACTGTATCA ATGAGTTGAT GGATACCTTG GTTGCACATT CCAACATCTT TGTTGGAGAG 
AACATTTTGG AAGAGAGTGA GAACTTACAC AATTTTGATC AGCCACTGCG TGTACGAGGC 
TGCATCCTAA CTCTGGTGGA GCGAATGGAT GAAGAATTTA CCAAAATAAT GCAAAATACT 
GATCCTCACT CCCAAGAGTA TGTGGAACAT CTGAAGGATG AGGCACAAGT ATGTGCCATC 
ATTGAGCGTG TACAGCGCTA CCTGGAGGAG AAAGGTACCA CTGAGGAGAT CTGCCAGATC 
TACTTGAGGC GCATCCTGCA CACTTACTAC AAGTTTGATT ACAAGGCCCA TCAGCGTCAG 
CTTACTCCTC CGGAAGGGTC CTCAAAGTCT GAGCAAGACC AGGCAGAAAA TGAGGGTGAG 
GACTCAGCTG TGCTAATGGA AAGACTGTGC AAATACATCT ATGCCAAGGA CCGTACAGAC 
CGCATCCGTA CCTGTGCCAT CCTCTGCCAT ATCTACCATC ATGCGCTCCA CTCCCGCTGG 
TATCAGGCCC GTGACCTCAT GCTCATGAGC CACCTACAAG ACAACATCCA GCACGCAGAC 
CCGCCAGTAC AGATCCTGTA TAACCGTACC ATGGTGCAAC TGGGCATCTG TGCTTTCCGC 
CAAGGCCTGA CAAAGGATGC ACACAATGCA CTTCTGGATA TTCAGTCAAG TGGTCGTGCC 
AAGGAGCTTC TGGGCCAGGG TCTGCTGCTG CGCAGCCTCC AGGAGCGCAA CCAGGAACAG 
GAGAAGGTAG AGCGACGCCG GCAGGTGCCC TTTCACCTGC ACATCAACCT GGAACTGCTG 
GAGTGTGTGT ATCTGGTGTC TGCTATGCTC CTGGAGATCC CCTACATGGC TGCCCATGAG 
AGTGATGCCC GCCGACGCAT GATCAGCAAG CAGTTCCATC ACCAACTGCG GGTGGGCGAG 
CGGCAGCCCC TGCTAGGTCC TCCTGAGTCA ATGAGGGAGC ATGTGGTTGC TGCCTCCAAG 
GCCATGAAGA TGGGTGACTG GAAGACCTGC CACAGTTTCA TCATTAATGA AAAGATGAAT 
GGGAAAGTGT GGGACCTTTT CCCTGAGGCT GACAAAGTTC GCACCATGCT AGTTCGGAAG 
ATCCAGGAAG AGTCTCTGAG GACCTACCTT TTTACCTATA GCAGTGTCTA TGACTCAATC 
AGTATGGAGA CACTCTCAGA TATGTTTGAG CTGGATCTGC CCACTGTTCA CTCCATCATC 
AGCAAGATGA TCATTAATGA AGAATTGATG GCTTCCCTGG ACCAGCCAAC GCAGACGGTA 
GTGATGCACC GTACTGAGCC CACTGCCCAA CAGAACTTGG CTCTGCAGCT GGCTGAGAAG 
CTTGGCAGCC TAGTGGAGAA TAATGAACGT GTGTTTGACC ATAAGCAAGG AACCTATGGC 
GGCTATTTCC GAGACCAAAA GGATGGCTAC CGAAAAAATG AAGGCTATAT GCGCCGTGGT 
GGCTACCGCC AGCAGCAGTC TCAGACAGCT TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230288.1
CDS	528..3263
Translation	MSRFFTTGSDSESESSLSGEELVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYVRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITNYKQNPEQSADEDAEKNEEDSEGSSDEDEDDDGVSGTAFLKKKPDSSGESRKFHKKMEDDDEDSEDSEDEEWDTSSTSSDSDSEEEEGKQTVLASKFLKKAPTTEEDKKAAEKKREDKAKKKHDRKSKRMDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQVRGKKGTDRATQIELLQLLVQIASENNLGVGVIVKIKFNIIASLYDYNPNLATYMKPEMWQMCLDCINELMDTLVAHSNIFVGENILEESENLHNFDQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEICQIYLRRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMRRGGYRQQQSQTAY

Target ORF information:

RefSeq Version	XM_006230226.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 3, subunit C (Eif3c), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230226.2

ORF Insert Sequence:

ATGTCCCGGT TTTTCACCAC CGGCTCGGAC AGTGAGTCGG AGTCGTCCCT GTCCGGGGAG 
GAGCTCGTCA CCAAACCAGT CTCCGGGAAC TATGGCAAAC AGCCTTTGTT ACTGAGCGAG 
GATGAAGAGG ATACAAAGAG AGTTGTTCGA AGTGCCAAGG ACAAGAGGTT TGAGGAGCTG 
ACCAACCTTA TACGAACCAT CCGTAATGCC ATGAAGATTC GAGATGTCAC CAAGTGTCTA 
GAAGAGTTTG AACTCCTGGG AAAAGCCTAT GGGAAAGCCA AGAGTATTGT GGATAAGGAG 
GGTGTCCCCC GATTCTATGT CCGGATATTG GCTGACCTGG AGGACTATCT TAATGAGCTT 
TGGGAAGATA AGGAAGGGAA AAAGAAGATG AATAAAAACA ATGCCAAGGC TCTGAGTACA 
TTGCGCCAGA AGATCCGAAA ATACAACCGA GATTTTGAGT CTCACATCAC CAACTATAAG 
CAGAACCCTG AACAATCTGC AGATGAAGAT GCAGAAAAGA ATGAGGAAGA CTCAGAAGGC 
TCTTCAGATG AGGATGAAGA TGACGATGGA GTCAGTGGTA CAGCCTTCTT GAAGAAGAAA 
CCAGACTCTT CTGGGGAGAG TCGAAAGTTC CACAAAAAGA TGGAGGATGA TGATGAGGAC 
TCTGAAGATT CTGAGGATGA AGAATGGGAC ACCAGTTCCA CATCTTCTGA TTCAGACTCC 
GAAGAAGAAG AAGGAAAACA AACTGTTCTG GCCTCAAAGT TCCTTAAAAA GGCACCCACC 
ACAGAGGAGG ACAAAAAGGC AGCTGAAAAG AAACGGGAAG ACAAAGCCAA GAAGAAGCAC 
GATAGGAAGT CTAAGCGCAT GGATGAGGAA GAGGAGGACA ATGAAGGCGG GGAGTGGGAA 
CGGGTCCGAG GCGGCGTACC ACTTGTTAAG GAGAAACCAA AAATGTTTGC CAAGGGAACA 
GAGATCACTC ATGCTGTTGT CATCAAGAAG CTGAATGAGA TTCTACAGGT CAGAGGCAAG 
AAGGGAACAG ACCGTGCTAC CCAGATTGAA TTGCTCCAGC TGCTGGTTCA GATTGCTTCT 
GAAAACAACC TGGGGGTGGG TGTCATTGTC AAGATCAAGT TCAATATCAT TGCCTCTCTC 
TACGATTACA ACCCTAACCT GGCCACGTAC ATGAAGCCAG AGATGTGGCA GATGTGCCTG 
GACTGTATCA ATGAGTTGAT GGATACCTTG GTTGCACATT CCAACATCTT TGTTGGAGAG 
AACATTTTGG AAGAGAGTGA GAACTTACAC AATTTTGATC AGCCACTGCG TGTACGAGGC 
TGCATCCTAA CTCTGGTGGA GCGAATGGAT GAAGAATTTA CCAAAATAAT GCAAAATACT 
GATCCTCACT CCCAAGAGTA TGTGGAACAT CTGAAGGATG AGGCACAAGT ATGTGCCATC 
ATTGAGCGTG TACAGCGCTA CCTGGAGGAG AAAGGTACCA CTGAGGAGAT CTGCCAGATC 
TACTTGAGGC GCATCCTGCA CACTTACTAC AAGTTTGATT ACAAGGCCCA TCAGCGTCAG 
CTTACTCCTC CGGAAGGGTC CTCAAAGTCT GAGCAAGACC AGGCAGAAAA TGAGGGTGAG 
GACTCAGCTG TGCTAATGGA AAGACTGTGC AAATACATCT ATGCCAAGGA CCGTACAGAC 
CGCATCCGTA CCTGTGCCAT CCTCTGCCAT ATCTACCATC ATGCGCTCCA CTCCCGCTGG 
TATCAGGCCC GTGACCTCAT GCTCATGAGC CACCTACAAG ACAACATCCA GCACGCAGAC 
CCGCCAGTAC AGATCCTGTA TAACCGTACC ATGGTGCAAC TGGGCATCTG TGCTTTCCGC 
CAAGGCCTGA CAAAGGATGC ACACAATGCA CTTCTGGATA TTCAGTCAAG TGGTCGTGCC 
AAGGAGCTTC TGGGCCAGGG TCTGCTGCTG CGCAGCCTCC AGGAGCGCAA CCAGGAACAG 
GAGAAGGTAG AGCGACGCCG GCAGGTGCCC TTTCACCTGC ACATCAACCT GGAACTGCTG 
GAGTGTGTGT ATCTGGTGTC TGCTATGCTC CTGGAGATCC CCTACATGGC TGCCCATGAG 
AGTGATGCCC GCCGACGCAT GATCAGCAAG CAGTTCCATC ACCAACTGCG GGTGGGCGAG 
CGGCAGCCCC TGCTAGGTCC TCCTGAGTCA ATGAGGGAGC ATGTGGTTGC TGCCTCCAAG 
GCCATGAAGA TGGGTGACTG GAAGACCTGC CACAGTTTCA TCATTAATGA AAAGATGAAT 
GGGAAAGTGT GGGACCTTTT CCCTGAGGCT GACAAAGTTC GCACCATGCT AGTTCGGAAG 
ATCCAGGAAG AGTCTCTGAG GACCTACCTT TTTACCTATA GCAGTGTCTA TGACTCAATC 
AGTATGGAGA CACTCTCAGA TATGTTTGAG CTGGATCTGC CCACTGTTCA CTCCATCATC 
AGCAAGATGA TCATTAATGA AGAATTGATG GCTTCCCTGG ACCAGCCAAC GCAGACGGTA 
GTGATGCACC GTACTGAGCC CACTGCCCAA CAGAACTTGG CTCTGCAGCT GGCTGAGAAG 
CTTGGCAGCC TAGTGGAGAA TAATGAACGT GTGTTTGACC ATAAGCAAGG AACCTATGGC 
GGCTATTTCC GAGACCAAAA GGATGGCTAC CGAAAAAATG AAGGCTATAT GCGCCGTGGT 
GGCTACCGCC AGCAGCAGTC TCAGACAGCT TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.
Nature522(7554)111-4(2015 Jun)
Lee AS,Kranzusch PJ,Cate JH

The scanning mechanism of eukaryotic translation initiation.
Annual review of biochemistry83779-812(2014)
Hinnebusch AG

Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome.
The Journal of biological chemistry288(46)32932-40(2013 Nov)
Villa N,Do A,Hershey JW,Fraser CS

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.
The Journal of biological chemistry288(42)30087-93(2013 Oct)
Zeng L,Wan Y,Li D,Wu J,Shao M,Chen J,Hui L,Ji H,Zhu X

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

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Eif3c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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