Clip2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clip2
Entrez Gene ID	29264
Full Name	CAP-GLY domain containing linker protein 2
Synonyms	CLIP-115,Cyln2
General protein information	Preferred Names CAP-GLY domain containing linker protein 2 Names CAP-Gly domain-containing linker protein 2 cytoplasmic linker 2 cytoplasmic linker protein 115 cytoplasmic linker protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q12
Summary	cytoplasmic linker protein; thought to mediate the interaction between membranous organelles and microtubules; human homolog associated with Williams Syndrome [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006249136.3	XP_006249198.1	CAP-Gly domain-containing linker protein 2 isoform X1
NM_021997.2	NP_068837.2	CAP-Gly domain-containing linker protein 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	CLIP2	NP_003379.3
Pan troglodytes (chimpanzee)	CLIP2	XP_001150007.1
Canis lupus familiaris (dog)	CLIP2	XP_005621069.1
Mus musculus (house mouse)	Clip2	NP_034120.2
Rattus norvegicus (Norway rat)	Clip2	NP_068837.1
Bos taurus (cattle)	CLIP2	NP_001179049.1
Danio rerio (zebrafish)	clip2	XP_684289.2
Gallus gallus (chicken)	CLIP2	XP_415736.4
Xenopus tropicalis (tropical clawed frog)	clip2	XP_002932337.2

Gene Ontology
Bibliography

Related articles in PubMed

Cytoplasmic linker proteins regulate neuronal polarization through microtubule and growth cone dynamics.
Neukirchen D, Bradke F
The Journal of neuroscience : the official journal of the Society for Neuroscience31(4)1528-38(2011 Jan)

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.
Peris L, Thery M, Faur? J, Saoudi Y, Lafanech?re L, Chilton JK, Gordon-Weeks P, Galjart N, Bornens M, Wordeman L, Wehland J, Andrieux A, Job D
The Journal of cell biology174(6)839-49(2006 Sep)

EB1 and EB3 control CLIP dissociation from the ends of growing microtubules.
Komarova Y, Lansbergen G, Galjart N, Grosveld F, Borisy GG, Akhmanova A
Molecular biology of the cell16(11)5334-45(2005 Nov)

Proteomic identification of brain proteins that interact with dynein light chain LC8.
Navarro-L?rida I, Mart?nez Moreno M, Roncal F, Gavilanes F, Albar JP, Rodr?guez-Crespo I
Proteomics4(2)339-46(2004 Feb)

Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice.
Hoogenraad CC, Koekkoek B, Akhmanova A, Krugers H, Dortland B, Miedema M, van Alphen A, Kistler WM, Jaegle M, Koutsourakis M, Van Camp N, Verhoye M, van der Linden A, Kaverina I, Grosveld F, De Zeeuw CI, Galjart N
Nature genetics32(1)116-27(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CLIPs enable neuronal polarization by controlling the stabilization of microtubules and growth cone dynamics.
Title: Cytoplasmic linker proteins regulate neuronal polarization through microtubule and growth cone dynamics.

The following Clip2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clip2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa43243	NM_021997.2 Latest version!	Rattus norvegicus CAP-GLY domain containing linker protein 2 (Clip2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa34756	XM_006249136.3 Latest version!	Rattus norvegicus CAP-GLY domain containing linker protein 2 (Clip2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clip2 ( NM_021997.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_068837.2 Rattus norvegicus CAP-GLY domain containing linker protein 2 (Clip2), mRNA.

Price & Availability↑

CloneID	ORa43243
Clone ID Related Accession (Same CDS sequence)	NM_021997.2
Accession Version	NM_021997.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3144bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	CAP-Gly domain-containing linker protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC094811.7. On May 5, 2015 this sequence version replaced NM_021997.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AJ000485.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGAAGC CCAGTGGCCT GAAGCCCCCT GGCCGAGGGG GGAAGCACTC CAGTCCCGTG 
GGTAGGCCCT CCATCGGGTC TGCCTCATCT TCTGTGGTGG CATCGGCGAG CGGCTCCAAA 
GAAGGGTCTC CCCTGCACAA GCAGGCGTCG GGCCCCTCCT CGGCTGGAGC CACCACTACT 
GTCTCCGAGA AGCCAGGTCC AAAGGCAGCC GAAGTGGGTG ATGACTTCTT GGGAGACTTC 
GTGGTGGGCG AGAGGGTGTG GGTGAATGGC GTGAAGCCCG GCGTGGTGCA GTACCTGGGT 
GAGACACAGT TTGCGCCAGG CCAGTGGGCC GGCGTGGTCT TGGATGATCC TGTGGGCAAG 
AACGATGGAG CTGTGGGTGG CGTGCGCTAC TTCGAGTGCC CAGCTCTACA GGGCATCTTC 
ACACGGCCCT CCAAGCTGAC CCGCCAGCCC GCAGCTGAGG GCTCCGGCAG TGACGCCCAC 
TCAGTGGAAT CCCTCACCGC CCAGAACCTG TCCCTGCATT CTGGCACGGC CACGCCCCCA 
CTCACCGGCC GAGTCATCCC CCTGCGGGAG AGTGTTCTCA ACAGCTCCGT GAAGACGGGC 
AATGAGTCTG GCTCCAACCT CTCGGACAGT GGTTCTGTGA AGCGTGGTGA CAAGGACCTC 
CACCTGGGAG ACCGTGTGCT GGTTGGTGGG ACGAAGACCG GTGTGGTACG ATATGTTGGG 
GAGACGGACT TTGCCAAAGG CGAGTGGTGT GGTGTGGAGC TGGACGAGCC CCTTGGGAAG 
AACGATGGGG CAGTGGCAGG CACCAGGTAC TTCCAGTGCC CACCCAAGTT CGGTCTCTTT 
GCACCAATCC ACAAGGTCAT CCGAATTGGC TTCCCATCTA CCAGTCCAGC CAAGGCCAAG 
AAGACCAAGC GCATGGCTAT GGGTGTCTCA GCCTTGACCC ACAGCCCCAG CAGTTCTTCC 
ATCAGCTCTG TCAGCTCTGT GGCCTCCTCT GTTGGTGGCC GGCCGAGCCG TAGTGGCCTG 
CTCACAGAGA CCTCTTCACG CTATGCCCGG AAGATCTCAG GCACCACAGC CCTGCAGGAG 
GCACTGAAGG AGAAACAGCA GCACATCGAA CAGCTGCTGG CTGAGCGTGA CTTGGAGAGG 
GCAGAAGTAG CCAAGGCTAC CAGTCATATC TGTGAGGTGG AGAAGGAAAT TGCCCTGCTG 
AAGGCACAGC ATGAGCAGTA TGTTGCAGAA GCTGAGGAGA AGCTGCAGCG GGCACGGTTG 
CTGGTGGAAA ACGTGAGGAA GGAGAAGGTG GATCTGTCCA ATCAGCTGGA GGAGGAGAGG 
AGGAAGGTGG AGGACCTGCA GTTCCGGGTG GAAGAAGAGT CCATCACCAA AGGAGACTTG 
GAGACCCAGA CCCAGCTGGA GCACGCGCGC ATTGGGGAGC TGGAGCAGAG TCTGCTATTG 
GAGAAGGCGC AGGCCGAGCG GCTGCTCAGA GAATTAGCGG ATAACAGGCT GACCACAGTG 
GCTGAGAAGT CTCGGGTGCT GCAGTTAGAA GAAGAGCTGA GCCTGCGGCG TGGTGAGATC 
GAAGAGCTAC AACACTGCCT CCTCCAGTCA GGTCCACCAC CTGCGGACCA CCCAGAGGCC 
GCTGAGACCC TGCGGCTGCG AGAGCGGCTG CTGTCGGCTA GCAAGGAGCA CCAGCGGGAC 
AGCACCCTGC TCCAGGACAA GTATGAGCAC ATGCTAAAGA CGTACCAGAC AGAAGTGGAC 
AAGCTTCGGG CAGCCAACGA GAAGTACGCT CAGGAAGTGG CAGACCTCAA GGCCAAGGTC 
CAGCAGGCCA CCACCGAGAA CATGGGGCTC ATGGACAACT GGAAATCCAA GCTGGACTCT 
CTGGCCTCCG ATCACCAGAA ATCTTTAGAA GACCTGAAGG CCACGCTGAA CTCTGGCCCA 
GGCGCCCAGC AGAAGGAGAT TGGCGAGCTG AAGGCCCTGG TGGAGGGCAT CAAAATGGAG 
CACCAACTGG AGTTAGGGAA CCTGCAGGCC AAGCATGACT TAGAGACGGC CATGCATGGG 
AAGGAGAAAG AGGGCCTGCG GCAGAAGCTG CAAGAGGCCC AGGAGGAGCT GGCCGGGCTG 
CAGCAGCACT GGAGGGCACA GCTGGAGGAG CAGGCCAGCC AGCACCGGCT GGAGCTACAA 
GAAGCCCAGG ACCAATGTCG TGACGCCCAG CTACGTGTGC AGGAGCTGGA GGGACTGGAT 
GTGGAATACC GCGGCCAGGC TCAGGCCATC GAGTTCCTCA AAGAACAGAT CTCGCTGGCT 
GAAAAGAAGA TGCTGGATTA CGAGATGTTG CAGAGGGCGG AAGCCCAGAG CAGGCAGGAG 
GCCGAGCGGC TGCGGGAAAA GCTTCTGGTG GCTGAGAATA GACTGCAGGC TGTCGAGTCC 
CTGTGCTCAG CCCAGCACAG CCATGTGATC GAGTCCAATG ACCTTTCTGA GGAGAAGATT 
CGGATGAAGG AGACTGTGGA GGGCCTGCAG GACAAGCTGA ACAAGAGGGA CAAAGAGGTG 
GCAGCCTTGA CATCCCAGAT GGACATGCTC AGGGCCCAAG TAAGTGCTCT CGAGAACAAG 
TGCAAATCAG GAGAGAAGAA GATAGACTCT CTCCTGAAGG AGAAGAGGCG GCTGGAGGCA 
GAGCTGGAGG CCGTGTCTCG GAAGACCCAT GATGCCTCTG GCCAGCTGGT CCACATCAGC 
CAAGAGTTGC TACGGAAGGA GAGGAGTCTG AATGAGCTGA GGGTGTTGCT GTTAGAAGCC 
AATCGGCACT CCCCAGGGCC CGAGAGAGAC CTGAGCCGTG AGGTACACAA AGCTGAATGG 
CGAATAAAGG AACAAAAACT GAAAGATGAC ATCCGGGGCC TGCGTGAAAA GCTGACCGGG 
CTGGACAAGG AGAAGTCCCT GTCGGAGCAG AAACGCTACT CCCTCATTGA CCCAGCTTCA 
GCGCCCGAGT TGCTGAGACT GCAACATCAG TTAGTGAGCA CGGAGGATGC CCTGCGGGAC 
GCACTGGACC AGGCCCAGCA GGTGGAGAGG CTGGTGGAGG CCCTGAGGGG CTGCTCAGAT 
AGGACTCAGA CCATCAGCAA TTCCGGTTCT GCCAATGGTA TCCACCAGCC AGACAAGGCC 
CACAAACAGG AGGACAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068837.2
CDS	286..3429
Translation	MQKPSGLKPPGRGGKHSSPVGRPSIGSASSSVVASASGSKEGSPLHKQASGPSSAGATTTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPAAEGSGSDAHSVESLTAQNLSLHSGTATPPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGDKDLHLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVENVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELSLRRGEIEELQHCLLQSGPPPADHPEAAETLRLRERLLSASKEHQRDSTLLQDKYEHMLKTYQTEVDKLRAANEKYAQEVADLKAKVQQATTENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKALVEGIKMEHQLELGNLQAKHDLETAMHGKEKEGLRQKLQEAQEELAGLQQHWRAQLEEQASQHRLELQEAQDQCRDAQLRVQELEGLDVEYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEAQSRQEAERLREKLLVAENRLQAVESLCSAQHSHVIESNDLSEEKIRMKETVEGLQDKLNKRDKEVAALTSQMDMLRAQVSALENKCKSGEKKIDSLLKEKRRLEAELEAVSRKTHDASGQLVHISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLREKLTGLDKEKSLSEQKRYSLIDPASAPELLRLQHQLVSTEDALRDALDQAQQVERLVEALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH

Target ORF information:

RefSeq Version	NM_021997.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CAP-GLY domain containing linker protein 2 (Clip2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021997.2

ORF Insert Sequence:

ATGCAGAAGC CCAGTGGCCT GAAGCCCCCT GGCCGAGGGG GGAAGCACTC CAGTCCCGTG 
GGTAGGCCCT CCATCGGGTC TGCCTCATCT TCTGTGGTGG CATCGGCGAG CGGCTCCAAA 
GAAGGGTCTC CCCTGCACAA GCAGGCGTCG GGCCCCTCCT CGGCTGGAGC CACCACTACT 
GTCTCCGAGA AGCCAGGTCC AAAGGCAGCC GAAGTGGGTG ATGACTTCTT GGGAGACTTC 
GTGGTGGGCG AGAGGGTGTG GGTGAATGGC GTGAAGCCCG GCGTGGTGCA GTACCTGGGT 
GAGACACAGT TTGCGCCAGG CCAGTGGGCC GGCGTGGTCT TGGATGATCC TGTGGGCAAG 
AACGATGGAG CTGTGGGTGG CGTGCGCTAC TTCGAGTGCC CAGCTCTACA GGGCATCTTC 
ACACGGCCCT CCAAGCTGAC CCGCCAGCCC GCAGCTGAGG GCTCCGGCAG TGACGCCCAC 
TCAGTGGAAT CCCTCACCGC CCAGAACCTG TCCCTGCATT CTGGCACGGC CACGCCCCCA 
CTCACCGGCC GAGTCATCCC CCTGCGGGAG AGTGTTCTCA ACAGCTCCGT GAAGACGGGC 
AATGAGTCTG GCTCCAACCT CTCGGACAGT GGTTCTGTGA AGCGTGGTGA CAAGGACCTC 
CACCTGGGAG ACCGTGTGCT GGTTGGTGGG ACGAAGACCG GTGTGGTACG ATATGTTGGG 
GAGACGGACT TTGCCAAAGG CGAGTGGTGT GGTGTGGAGC TGGACGAGCC CCTTGGGAAG 
AACGATGGGG CAGTGGCAGG CACCAGGTAC TTCCAGTGCC CACCCAAGTT CGGTCTCTTT 
GCACCAATCC ACAAGGTCAT CCGAATTGGC TTCCCATCTA CCAGTCCAGC CAAGGCCAAG 
AAGACCAAGC GCATGGCTAT GGGTGTCTCA GCCTTGACCC ACAGCCCCAG CAGTTCTTCC 
ATCAGCTCTG TCAGCTCTGT GGCCTCCTCT GTTGGTGGCC GGCCGAGCCG TAGTGGCCTG 
CTCACAGAGA CCTCTTCACG CTATGCCCGG AAGATCTCAG GCACCACAGC CCTGCAGGAG 
GCACTGAAGG AGAAACAGCA GCACATCGAA CAGCTGCTGG CTGAGCGTGA CTTGGAGAGG 
GCAGAAGTAG CCAAGGCTAC CAGTCATATC TGTGAGGTGG AGAAGGAAAT TGCCCTGCTG 
AAGGCACAGC ATGAGCAGTA TGTTGCAGAA GCTGAGGAGA AGCTGCAGCG GGCACGGTTG 
CTGGTGGAAA ACGTGAGGAA GGAGAAGGTG GATCTGTCCA ATCAGCTGGA GGAGGAGAGG 
AGGAAGGTGG AGGACCTGCA GTTCCGGGTG GAAGAAGAGT CCATCACCAA AGGAGACTTG 
GAGACCCAGA CCCAGCTGGA GCACGCGCGC ATTGGGGAGC TGGAGCAGAG TCTGCTATTG 
GAGAAGGCGC AGGCCGAGCG GCTGCTCAGA GAATTAGCGG ATAACAGGCT GACCACAGTG 
GCTGAGAAGT CTCGGGTGCT GCAGTTAGAA GAAGAGCTGA GCCTGCGGCG TGGTGAGATC 
GAAGAGCTAC AACACTGCCT CCTCCAGTCA GGTCCACCAC CTGCGGACCA CCCAGAGGCC 
GCTGAGACCC TGCGGCTGCG AGAGCGGCTG CTGTCGGCTA GCAAGGAGCA CCAGCGGGAC 
AGCACCCTGC TCCAGGACAA GTATGAGCAC ATGCTAAAGA CGTACCAGAC AGAAGTGGAC 
AAGCTTCGGG CAGCCAACGA GAAGTACGCT CAGGAAGTGG CAGACCTCAA GGCCAAGGTC 
CAGCAGGCCA CCACCGAGAA CATGGGGCTC ATGGACAACT GGAAATCCAA GCTGGACTCT 
CTGGCCTCCG ATCACCAGAA ATCTTTAGAA GACCTGAAGG CCACGCTGAA CTCTGGCCCA 
GGCGCCCAGC AGAAGGAGAT TGGCGAGCTG AAGGCCCTGG TGGAGGGCAT CAAAATGGAG 
CACCAACTGG AGTTAGGGAA CCTGCAGGCC AAGCATGACT TAGAGACGGC CATGCATGGG 
AAGGAGAAAG AGGGCCTGCG GCAGAAGCTG CAAGAGGCCC AGGAGGAGCT GGCCGGGCTG 
CAGCAGCACT GGAGGGCACA GCTGGAGGAG CAGGCCAGCC AGCACCGGCT GGAGCTACAA 
GAAGCCCAGG ACCAATGTCG TGACGCCCAG CTACGTGTGC AGGAGCTGGA GGGACTGGAT 
GTGGAATACC GCGGCCAGGC TCAGGCCATC GAGTTCCTCA AAGAACAGAT CTCGCTGGCT 
GAAAAGAAGA TGCTGGATTA CGAGATGTTG CAGAGGGCGG AAGCCCAGAG CAGGCAGGAG 
GCCGAGCGGC TGCGGGAAAA GCTTCTGGTG GCTGAGAATA GACTGCAGGC TGTCGAGTCC 
CTGTGCTCAG CCCAGCACAG CCATGTGATC GAGTCCAATG ACCTTTCTGA GGAGAAGATT 
CGGATGAAGG AGACTGTGGA GGGCCTGCAG GACAAGCTGA ACAAGAGGGA CAAAGAGGTG 
GCAGCCTTGA CATCCCAGAT GGACATGCTC AGGGCCCAAG TAAGTGCTCT CGAGAACAAG 
TGCAAATCAG GAGAGAAGAA GATAGACTCT CTCCTGAAGG AGAAGAGGCG GCTGGAGGCA 
GAGCTGGAGG CCGTGTCTCG GAAGACCCAT GATGCCTCTG GCCAGCTGGT CCACATCAGC 
CAAGAGTTGC TACGGAAGGA GAGGAGTCTG AATGAGCTGA GGGTGTTGCT GTTAGAAGCC 
AATCGGCACT CCCCAGGGCC CGAGAGAGAC CTGAGCCGTG AGGTACACAA AGCTGAATGG 
CGAATAAAGG AACAAAAACT GAAAGATGAC ATCCGGGGCC TGCGTGAAAA GCTGACCGGG 
CTGGACAAGG AGAAGTCCCT GTCGGAGCAG AAACGCTACT CCCTCATTGA CCCAGCTTCA 
GCGCCCGAGT TGCTGAGACT GCAACATCAG TTAGTGAGCA CGGAGGATGC CCTGCGGGAC 
GCACTGGACC AGGCCCAGCA GGTGGAGAGG CTGGTGGAGG CCCTGAGGGG CTGCTCAGAT 
AGGACTCAGA CCATCAGCAA TTCCGGTTCT GCCAATGGTA TCCACCAGCC AGACAAGGCC 
CACAAACAGG AGGACAAACA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clip2 ( XM_006249136.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249198.1 Rattus norvegicus CAP-GLY domain containing linker protein 2 (Clip2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa34756
Clone ID Related Accession (Same CDS sequence)	XM_006249136.3
Accession Version	XM_006249136.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3039bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	CAP-Gly domain-containing linker protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249136.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGAAGC CCAGTGGCCT GAAGCCCCCT GGCCGAGGGG GGAAGCACTC CAGTCCCGTG 
GGTAGGCCCT CCATCGGGTC TGCCTCATCT TCTGTGGTGG CATCGGCGAG CGGCTCCAAA 
GAAGGGTCTC CCCTGCACAA GCAGGCGTCG GGCCCCTCCT CGGCTGGAGC CACCACTACT 
GTCTCCGAGA AGCCAGGTCC AAAGGCAGCC GAAGTGGGTG ATGACTTCTT GGGAGACTTC 
GTGGTGGGCG AGAGGGTGTG GGTGAATGGC GTGAAGCCCG GCGTGGTGCA GTACCTGGGT 
GAGACACAGT TTGCGCCAGG CCAGTGGGCC GGCGTGGTCT TGGATGATCC TGTGGGCAAG 
AACGATGGAG CTGTGGGTGG CGTGCGCTAC TTCGAGTGCC CAGCTCTACA GGGCATCTTC 
ACACGGCCCT CCAAGCTGAC CCGCCAGCCC GCAGCTGAGG GCTCCGGCAG TGACGCCCAC 
TCAGTGGAAT CCCTCACCGC CCAGAACCTG TCCCTGCATT CTGGCACGGC CACGCCCCCA 
CTCACCGGCC GAGTCATCCC CCTGCGGGAG AGTGTTCTCA ACAGCTCCGT GAAGACGGGC 
AATGAGTCTG GCTCCAACCT CTCGGACAGT GGTTCTGTGA AGCGTGGTGA CAAGGACCTC 
CACCTGGGAG ACCGTGTGCT GGTTGGTGGG ACGAAGACCG GTGTGGTACG ATATGTTGGG 
GAGACGGACT TTGCCAAAGG CGAGTGGTGT GGTGTGGAGC TGGACGAGCC CCTTGGGAAG 
AACGATGGGG CAGTGGCAGG CACCAGGTAC TTCCAGTGCC CACCCAAGTT CGGTCTCTTT 
GCACCAATCC ACAAGGTCAT CCGAATTGGC TTCCCATCTA CCAGTCCAGC CAAGGCCAAG 
AAGACCAAGC GCATGGCTAT GGGTGTCTCA GCCTTGACCC ACAGCCCCAG CAGTTCTTCC 
ATCAGCTCTG TCAGCTCTGT GGCCTCCTCT GTTGGTGGCC GGCCGAGCCG TAGTGGCCTG 
CTCACAGAGA CCTCTTCACG CTATGCCCGG AAGATCTCAG GCACCACAGC CCTGCAGGAG 
GCACTGAAGG AGAAACAGCA GCACATCGAA CAGCTGCTGG CTGAGCGTGA CTTGGAGAGG 
GCAGAAGTAG CCAAGGCTAC CAGTCATATC TGTGAGGTGG AGAAGGAAAT TGCCCTGCTG 
AAGGCACAGC ATGAGCAGTA TGTTGCAGAA GCTGAGGAGA AGCTGCAGCG GGCACGGTTG 
CTGGTGGAAA ACGTGAGGAA GGAGAAGGTG GATCTGTCCA ATCAGCTGGA GGAGGAGAGG 
AGGAAGGTGG AGGACCTGCA GTTCCGGGTG GAAGAAGAGT CCATCACCAA AGGAGACTTG 
GAGCTGACCA CAGTGGCTGA GAAGTCTCGG GTGCTGCAGT TAGAAGAAGA GCTGAGCCTG 
CGGCGTGGTG AGATCGAAGA GCTACAACAC TGCCTCCTCC AGTCAGGTCC ACCACCTGCG 
GACCACCCAG AGGCCGCTGA GACCCTGCGG CTGCGAGAGC GGCTGCTGTC GGCTAGCAAG 
GAGCACCAGC GGGACAGCAC CCTGCTCCAG GACAAGTATG AGCACATGCT AAAGACGTAC 
CAGACAGAAG TGGACAAGCT TCGGGCAGCC AACGAGAAGT ACGCTCAGGA AGTGGCAGAC 
CTCAAGGCCA AGGTCCAGCA GGCCACCACC GAGAACATGG GGCTCATGGA CAACTGGAAA 
TCCAAGCTGG ACTCTCTGGC CTCCGATCAC CAGAAATCTT TAGAAGACCT GAAGGCCACG 
CTGAACTCTG GCCCAGGCGC CCAGCAGAAG GAGATTGGCG AGCTGAAGGC CCTGGTGGAG 
GGCATCAAAA TGGAGCACCA ACTGGAGTTA GGGAACCTGC AGGCCAAGCA TGACTTAGAG 
ACGGCCATGC ATGGGAAGGA GAAAGAGGGC CTGCGGCAGA AGCTGCAAGA GGCCCAGGAG 
GAGCTGGCCG GGCTGCAGCA GCACTGGAGG GCACAGCTGG AGGAGCAGGC CAGCCAGCAC 
CGGCTGGAGC TACAAGAAGC CCAGGACCAA TGTCGTGACG CCCAGCTACG TGTGCAGGAG 
CTGGAGGGAC TGGATGTGGA ATACCGCGGC CAGGCTCAGG CCATCGAGTT CCTCAAAGAA 
CAGATCTCGC TGGCTGAAAA GAAGATGCTG GATTACGAGA TGTTGCAGAG GGCGGAAGCC 
CAGAGCAGGC AGGAGGCCGA GCGGCTGCGG GAAAAGCTTC TGGTGGCTGA GAATAGACTG 
CAGGCTGTCG AGTCCCTGTG CTCAGCCCAG CACAGCCATG TGATCGAGTC CAATGACCTT 
TCTGAGGAGA AGATTCGGAT GAAGGAGACT GTGGAGGGCC TGCAGGACAA GCTGAACAAG 
AGGGACAAAG AGGTGGCAGC CTTGACATCC CAGATGGACA TGCTCAGGGC CCAAGTAAGT 
GCTCTCGAGA ACAAGTGCAA ATCAGGAGAG AAGAAGATAG ACTCTCTCCT GAAGGAGAAG 
AGGCGGCTGG AGGCAGAGCT GGAGGCCGTG TCTCGGAAGA CCCATGATGC CTCTGGCCAG 
CTGGTCCACA TCAGCCAAGA GTTGCTACGG AAGGAGAGGA GTCTGAATGA GCTGAGGGTG 
TTGCTGTTAG AAGCCAATCG GCACTCCCCA GGGCCCGAGA GAGACCTGAG CCGTGAGGTA 
CACAAAGCTG AATGGCGAAT AAAGGAACAA AAACTGAAAG ATGACATCCG GGGCCTGCGT 
GAAAAGCTGA CCGGGCTGGA CAAGGAGAAG TCCCTGTCGG AGCAGAAACG CTACTCCCTC 
ATTGACCCAG CTTCAGCGCC CGAGTTGCTG AGACTGCAAC ATCAGTTAGT GAGCACGGAG 
GATGCCCTGC GGGACGCACT GGACCAGGCC CAGCAGGTGG AGAGGCTGGT GGAGGCCCTG 
AGGGGCTGCT CAGATAGGAC TCAGACCATC AGCAATTCCG GTTCTGCCAA TGGTATCCAC 
CAGCCAGACA AGGCCCACAA ACAGGAGGAC AAACACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249198.1
CDS	464..3502
Translation	MQKPSGLKPPGRGGKHSSPVGRPSIGSASSSVVASASGSKEGSPLHKQASGPSSAGATTTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPAAEGSGSDAHSVESLTAQNLSLHSGTATPPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGDKDLHLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVENVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLELTTVAEKSRVLQLEEELSLRRGEIEELQHCLLQSGPPPADHPEAAETLRLRERLLSASKEHQRDSTLLQDKYEHMLKTYQTEVDKLRAANEKYAQEVADLKAKVQQATTENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKALVEGIKMEHQLELGNLQAKHDLETAMHGKEKEGLRQKLQEAQEELAGLQQHWRAQLEEQASQHRLELQEAQDQCRDAQLRVQELEGLDVEYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEAQSRQEAERLREKLLVAENRLQAVESLCSAQHSHVIESNDLSEEKIRMKETVEGLQDKLNKRDKEVAALTSQMDMLRAQVSALENKCKSGEKKIDSLLKEKRRLEAELEAVSRKTHDASGQLVHISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLREKLTGLDKEKSLSEQKRYSLIDPASAPELLRLQHQLVSTEDALRDALDQAQQVERLVEALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH

Target ORF information:

RefSeq Version	XM_006249136.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CAP-GLY domain containing linker protein 2 (Clip2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249136.3

ORF Insert Sequence:

ATGCAGAAGC CCAGTGGCCT GAAGCCCCCT GGCCGAGGGG GGAAGCACTC CAGTCCCGTG 
GGTAGGCCCT CCATCGGGTC TGCCTCATCT TCTGTGGTGG CATCGGCGAG CGGCTCCAAA 
GAAGGGTCTC CCCTGCACAA GCAGGCGTCG GGCCCCTCCT CGGCTGGAGC CACCACTACT 
GTCTCCGAGA AGCCAGGTCC AAAGGCAGCC GAAGTGGGTG ATGACTTCTT GGGAGACTTC 
GTGGTGGGCG AGAGGGTGTG GGTGAATGGC GTGAAGCCCG GCGTGGTGCA GTACCTGGGT 
GAGACACAGT TTGCGCCAGG CCAGTGGGCC GGCGTGGTCT TGGATGATCC TGTGGGCAAG 
AACGATGGAG CTGTGGGTGG CGTGCGCTAC TTCGAGTGCC CAGCTCTACA GGGCATCTTC 
ACACGGCCCT CCAAGCTGAC CCGCCAGCCC GCAGCTGAGG GCTCCGGCAG TGACGCCCAC 
TCAGTGGAAT CCCTCACCGC CCAGAACCTG TCCCTGCATT CTGGCACGGC CACGCCCCCA 
CTCACCGGCC GAGTCATCCC CCTGCGGGAG AGTGTTCTCA ACAGCTCCGT GAAGACGGGC 
AATGAGTCTG GCTCCAACCT CTCGGACAGT GGTTCTGTGA AGCGTGGTGA CAAGGACCTC 
CACCTGGGAG ACCGTGTGCT GGTTGGTGGG ACGAAGACCG GTGTGGTACG ATATGTTGGG 
GAGACGGACT TTGCCAAAGG CGAGTGGTGT GGTGTGGAGC TGGACGAGCC CCTTGGGAAG 
AACGATGGGG CAGTGGCAGG CACCAGGTAC TTCCAGTGCC CACCCAAGTT CGGTCTCTTT 
GCACCAATCC ACAAGGTCAT CCGAATTGGC TTCCCATCTA CCAGTCCAGC CAAGGCCAAG 
AAGACCAAGC GCATGGCTAT GGGTGTCTCA GCCTTGACCC ACAGCCCCAG CAGTTCTTCC 
ATCAGCTCTG TCAGCTCTGT GGCCTCCTCT GTTGGTGGCC GGCCGAGCCG TAGTGGCCTG 
CTCACAGAGA CCTCTTCACG CTATGCCCGG AAGATCTCAG GCACCACAGC CCTGCAGGAG 
GCACTGAAGG AGAAACAGCA GCACATCGAA CAGCTGCTGG CTGAGCGTGA CTTGGAGAGG 
GCAGAAGTAG CCAAGGCTAC CAGTCATATC TGTGAGGTGG AGAAGGAAAT TGCCCTGCTG 
AAGGCACAGC ATGAGCAGTA TGTTGCAGAA GCTGAGGAGA AGCTGCAGCG GGCACGGTTG 
CTGGTGGAAA ACGTGAGGAA GGAGAAGGTG GATCTGTCCA ATCAGCTGGA GGAGGAGAGG 
AGGAAGGTGG AGGACCTGCA GTTCCGGGTG GAAGAAGAGT CCATCACCAA AGGAGACTTG 
GAGCTGACCA CAGTGGCTGA GAAGTCTCGG GTGCTGCAGT TAGAAGAAGA GCTGAGCCTG 
CGGCGTGGTG AGATCGAAGA GCTACAACAC TGCCTCCTCC AGTCAGGTCC ACCACCTGCG 
GACCACCCAG AGGCCGCTGA GACCCTGCGG CTGCGAGAGC GGCTGCTGTC GGCTAGCAAG 
GAGCACCAGC GGGACAGCAC CCTGCTCCAG GACAAGTATG AGCACATGCT AAAGACGTAC 
CAGACAGAAG TGGACAAGCT TCGGGCAGCC AACGAGAAGT ACGCTCAGGA AGTGGCAGAC 
CTCAAGGCCA AGGTCCAGCA GGCCACCACC GAGAACATGG GGCTCATGGA CAACTGGAAA 
TCCAAGCTGG ACTCTCTGGC CTCCGATCAC CAGAAATCTT TAGAAGACCT GAAGGCCACG 
CTGAACTCTG GCCCAGGCGC CCAGCAGAAG GAGATTGGCG AGCTGAAGGC CCTGGTGGAG 
GGCATCAAAA TGGAGCACCA ACTGGAGTTA GGGAACCTGC AGGCCAAGCA TGACTTAGAG 
ACGGCCATGC ATGGGAAGGA GAAAGAGGGC CTGCGGCAGA AGCTGCAAGA GGCCCAGGAG 
GAGCTGGCCG GGCTGCAGCA GCACTGGAGG GCACAGCTGG AGGAGCAGGC CAGCCAGCAC 
CGGCTGGAGC TACAAGAAGC CCAGGACCAA TGTCGTGACG CCCAGCTACG TGTGCAGGAG 
CTGGAGGGAC TGGATGTGGA ATACCGCGGC CAGGCTCAGG CCATCGAGTT CCTCAAAGAA 
CAGATCTCGC TGGCTGAAAA GAAGATGCTG GATTACGAGA TGTTGCAGAG GGCGGAAGCC 
CAGAGCAGGC AGGAGGCCGA GCGGCTGCGG GAAAAGCTTC TGGTGGCTGA GAATAGACTG 
CAGGCTGTCG AGTCCCTGTG CTCAGCCCAG CACAGCCATG TGATCGAGTC CAATGACCTT 
TCTGAGGAGA AGATTCGGAT GAAGGAGACT GTGGAGGGCC TGCAGGACAA GCTGAACAAG 
AGGGACAAAG AGGTGGCAGC CTTGACATCC CAGATGGACA TGCTCAGGGC CCAAGTAAGT 
GCTCTCGAGA ACAAGTGCAA ATCAGGAGAG AAGAAGATAG ACTCTCTCCT GAAGGAGAAG 
AGGCGGCTGG AGGCAGAGCT GGAGGCCGTG TCTCGGAAGA CCCATGATGC CTCTGGCCAG 
CTGGTCCACA TCAGCCAAGA GTTGCTACGG AAGGAGAGGA GTCTGAATGA GCTGAGGGTG 
TTGCTGTTAG AAGCCAATCG GCACTCCCCA GGGCCCGAGA GAGACCTGAG CCGTGAGGTA 
CACAAAGCTG AATGGCGAAT AAAGGAACAA AAACTGAAAG ATGACATCCG GGGCCTGCGT 
GAAAAGCTGA CCGGGCTGGA CAAGGAGAAG TCCCTGTCGG AGCAGAAACG CTACTCCCTC 
ATTGACCCAG CTTCAGCGCC CGAGTTGCTG AGACTGCAAC ATCAGTTAGT GAGCACGGAG 
GATGCCCTGC GGGACGCACT GGACCAGGCC CAGCAGGTGG AGAGGCTGGT GGAGGCCCTG 
AGGGGCTGCT CAGATAGGAC TCAGACCATC AGCAATTCCG GTTCTGCCAA TGGTATCCAC 
CAGCCAGACA AGGCCCACAA ACAGGAGGAC AAACACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cytoplasmic linker proteins regulate neuronal polarization through microtubule and growth cone dynamics.
The Journal of neuroscience : the official journal of the Society for Neuroscience31(4)1528-38(2011 Jan)
Neukirchen D,Bradke F

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.
The Journal of cell biology174(6)839-49(2006 Sep)
Peris L,Thery M,Faur? J,Saoudi Y,Lafanech?re L,Chilton JK,Gordon-Weeks P,Galjart N,Bornens M,Wordeman L,Wehland J,Andrieux A,Job D

EB1 and EB3 control CLIP dissociation from the ends of growing microtubules.
Molecular biology of the cell16(11)5334-45(2005 Nov)
Komarova Y,Lansbergen G,Galjart N,Grosveld F,Borisy GG,Akhmanova A

Proteomic identification of brain proteins that interact with dynein light chain LC8.
Proteomics4(2)339-46(2004 Feb)
Navarro-L?rida I,Mart?nez Moreno M,Roncal F,Gavilanes F,Albar JP,Rodr?guez-Crespo I

Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice.
Nature genetics32(1)116-27(2002 Sep)
Hoogenraad CC,Koekkoek B,Akhmanova A,Krugers H,Dortland B,Miedema M,van Alphen A,Kistler WM,Jaegle M,Koutsourakis M,Van Camp N,Verhoye M,van der Linden A,Kaverina I,Grosveld F,De Zeeuw CI,Galjart N

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Clip2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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