Dr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dr1
Entrez Gene ID	289881
Full Name	down-regulator of transcription 1, TBP-binding (negative cofactor 2)
General protein information	Preferred Names down-regulator of transcription 1, TBP-binding (negative cofactor 2) Names protein Dr1 NC2-beta TATA-binding protein-associated phosphoprotein negative cofactor 2-beta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001011914.1	NP_001011914.1	protein Dr1

Pathways from BioSystems

Homologies

Homo sapiens (human)	DR1	NP_001929.1
Saccharomyces cerevisiae (baker's yeast)	NCB2	NP_010685.1
Kluyveromyces lactis	KLLA0C06611g	XP_452492.1
Magnaporthe oryzae (rice blast fungus)	MGG_02824	XP_003720914.1
Oryza sativa (rice)	Os08g0383700	NP_001061698.1
Rattus norvegicus (Norway rat)	Dr1	NP_001011914.1
Gallus gallus (chicken)	DR1	NP_001008478.1
Danio rerio (zebrafish)	LOC100536903	XP_005168804.1
Danio rerio (zebrafish)	dr1	NP_001070782.1
Arabidopsis thaliana (thale cress)	NF-YB13	NP_851060.1
Rattus norvegicus (Norway rat)	LOC100910207	XP_003751365.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010322	XP_318244.2
Arabidopsis thaliana (thale cress)	NF-YB12	NP_001078545.1
Xenopus tropicalis (tropical clawed frog)	dr1	NP_001039251.1
Canis lupus familiaris (dog)	DR1	XP_537068.1
Bos taurus (cattle)	DR1	NP_001039984.1
Mus musculus (house mouse)	Dr1	NP_080382.2
Eremothecium gossypii	AGOS_AFR397C	NP_985944.1
Neurospora crassa	NCU02017	XP_964882.2
Pan troglodytes (chimpanzee)	DR1	XP_001154876.1
	DR1	XP_001102017.1
Drosophila melanogaster (fruit fly)	NC2beta	NP_609736.1
Caenorhabditis elegans (roundworm)	dro-1	NP_499750.1
Schizosaccharomyces pombe (fission yeast)	SPBC30D10.02	NP_596283.1

Gene Ontology
Bibliography

Related articles in PubMed

ATAC-king the complexity of SAGA during evolution.
Spedale G, Timmers HT, Pijnappel WW
Genes & development26(6)527-41(2012 Mar)

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
Krebs AR, Demmers J, Karmodiya K, Chang NC, Chang AC, Tora L
EMBO reports11(7)541-7(2010 Jul)

The double-histone-acetyltransferase complex ATAC is essential for mammalian development.
Guelman S, Kozuka K, Mao Y, Pham V, Solloway MJ, Wang J, Wu J, Lill JR, Zha J
Molecular and cellular biology29(5)1176-88(2009 Mar)

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
Wang YL, Faiola F, Xu M, Pan S, Martinez E
The Journal of biological chemistry283(49)33808-15(2008 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01510	NM_001011914.1 Latest version!	Rattus norvegicus down-regulator of transcription 1 (Dr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dr1 ( NM_001011914.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001011914.1 Rattus norvegicus down-regulator of transcription 1 (Dr1), mRNA.

Price & Availability↑

CloneID	ORa01510
Clone ID Related Accession (Same CDS sequence)	NM_001011914.1
Accession Version	NM_001011914.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	protein Dr1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083822.1. On Feb 11, 2005 this sequence version replaced XM_214124.2. ##Evidence-Data-START## Transcript exon combination :: BC083822.1, EV768811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCCT CGTCTGGCAA CGACGATGAT CTCACTATCC CGAGAGCTGC TATAAATAAG 
ATGATCAAAG AGACTCTCCC TAATGTCAGG GTGGCCAACG ATGCCCGAGA GCTCGTAGTG 
AACTGCTGCA CTGAATTCAT TCACCTTATA TCTTCCGAAG CCAACGAGAT TTGTAACAAG 
TCAGAAAAGA AGACAATCTC ACCAGAGCAT GTCATCCAAG CACTAGAAAG TTTGGGCTTT 
GGCTCTTACA TCAGTGAAGT AAAAGAAGTC TTACAAGAAT GCAAGACAGT AGCATTAAAA 
AGAAGAAAGG CCAGTTCTCG TTTGGAAAAC CTTGGCATTC CTGAAGAAGA ATTATTGAGA 
CAGCAACAGG AATTATTTGC AAAAGCTAGA CAGCAACAAG CAGAATTGGC CCAACAGGAG 
TGGCTTCAGA TGCAGCAAGC AGCTCAGCAG GCCCAGTTGG CTGCTGCCTC AGCCAGTGCA 
TCCAATCAGG CCGGGTCTTC ACAGGACGAA GACGACGACG ACGACATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011914.1
CDS	622..1152
Translation	MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEDDDDDI

Target ORF information:

RefSeq Version	NM_001011914.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus down-regulator of transcription 1 (Dr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011914.1

ORF Insert Sequence:

ATGGCTTCCT CGTCTGGCAA CGACGATGAT CTCACTATCC CGAGAGCTGC TATAAATAAG 
ATGATCAAAG AGACTCTCCC TAATGTCAGG GTGGCCAACG ATGCCCGAGA GCTCGTAGTG 
AACTGCTGCA CTGAATTCAT TCACCTTATA TCTTCCGAAG CCAACGAGAT TTGTAACAAG 
TCAGAAAAGA AGACAATCTC ACCAGAGCAT GTCATCCAAG CACTAGAAAG TTTGGGCTTT 
GGCTCTTACA TCAGTGAAGT AAAAGAAGTC TTACAAGAAT GCAAGACAGT AGCATTAAAA 
AGAAGAAAGG CCAGTTCTCG TTTGGAAAAC CTTGGCATTC CTGAAGAAGA ATTATTGAGA 
CAGCAACAGG AATTATTTGC AAAAGCTAGA CAGCAACAAG CAGAATTGGC CCAACAGGAG 
TGGCTTCAGA TGCAGCAAGC AGCTCAGCAG GCCCAGTTGG CTGCTGCCTC AGCCAGTGCA 
TCCAATCAGG CCGGGTCTTC ACAGGACGAA GACGACGACG ACGACATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ATAC-king the complexity of SAGA during evolution.
Genes & development26(6)527-41(2012 Mar)
Spedale G,Timmers HT,Pijnappel WW

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
EMBO reports11(7)541-7(2010 Jul)
Krebs AR,Demmers J,Karmodiya K,Chang NC,Chang AC,Tora L

The double-histone-acetyltransferase complex ATAC is essential for mammalian development.
Molecular and cellular biology29(5)1176-88(2009 Mar)
Guelman S,Kozuka K,Mao Y,Pham V,Solloway MJ,Wang J,Wu J,Lill JR,Zha J

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
The Journal of biological chemistry283(49)33808-15(2008 Dec)
Wang YL,Faiola F,Xu M,Pan S,Martinez E