Lyzl6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lyzl6
Entrez Gene ID	287751
Full Name	lysozyme-like 6
Synonyms	Lyzb,RGD1306968
General protein information	Preferred Names lysozyme-like 6 Names lysozyme-like protein 6 lysozyme b
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006247503.3	XP_006247565.1	lysozyme-like protein 6 isoform X1
NM_001135833.1	NP_001129305.2	lysozyme-like protein 6 precursor

Pathways from BioSystems

Homologies

	LYZL6	XP_001114751.1
Canis lupus familiaris (dog)	LOC480492	XP_537611.4
Homo sapiens (human)	LYZL6	NP_001186880.1
Bos taurus (cattle)	LYZL6	NP_001039931.1
Rattus norvegicus (Norway rat)	Lyzl6	NP_001129305.2
Pan troglodytes (chimpanzee)	LYZL6	XP_523777.1
Mus musculus (house mouse)	Lyzl6	NP_081359.1

Gene Ontology
Bibliography

Related articles in PubMed

LYZL6, an acidic, bacteriolytic, human sperm-related protein, plays a role in fertilization.
Huang P, Li W, Yang Z, Zhang N, Xu Y, Bao J, Jiang D, Dong X
PloS one12(2)e0171452(2017)

Immunization against lysozyme-like proteins affect sperm function and fertility in the rat.
Narmadha G, Yenugu S
Journal of reproductive immunology118100-108(2016 11)

Characterisation of Lyzls in mice and antibacterial properties of human LYZL6.
Wei J, Li SJ, Shi H, Wang HY, Rong CT, Zhu P, Jin SH, Liu J, Li JY
Asian journal of andrology15(6)824-30(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study indicates a role for LYZL6 protein in sperm function
Title: Immunization against lysozyme-like proteins affect sperm function and fertility in the rat.

The following Lyzl6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lyzl6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04100	NM_001135833.1 Latest version!	Rattus norvegicus lysozyme-like 6 (Lyzl6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa04100	XM_006247503.3 Latest version!	Rattus norvegicus lysozyme-like 6 (Lyzl6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lyzl6 ( NM_001135833.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001129305.2 Rattus norvegicus lysozyme-like 6 (Lyzl6), mRNA.

Price & Availability↑

CloneID	ORa04100
Clone ID Related Accession (Same CDS sequence)	XM_006247503.3 , NM_001135833.1
Accession Version	NM_001135833.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-30
Organism	Rattus norvegicus(Norway rat)
Product	lysozyme-like protein 6 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07030524.1. On Oct 15, 2008 this sequence version replaced XM_213497.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689604, SAMN02642708 [ECO:0000348] ##Evidence-Data-END##

ATGATGATGA GGGTGCTGTT TATCTGTGTG GTGAGCTGCC TTCTGGTCGT GAATGATGGC 
AGCATCATCA ATCGCTGTAC CTTGGCCAGG ATTCTGTATC AAGAGGACTT GGATGGGTTT 
GAGGGCTACT CCCTGCCTCA CTGGCTGTGC TTGGCTTTTG TGGAGAGCAA ATTCAACATA 
TCAAAGGTGA CTGAGAATGC AGATGGTACC TTTGACTATG GAATCTTCCA GATCAATAGC 
CGTTACTGGT GCAATGACTA CCAGAGTCAT TCAGAGAACT TCTGCCGCCT GGACTGTGAA 
GAACTACTGA ATCCCAACCT CATTCCATCC ATCCACTGTG CAAAAATGAT TGTGTCTGGA 
TCTGGAGGGA TGAAGAACTG GGTAGATTGG AGGTTGCACT GTTTAGGACG GCCACTCTCC 
TACTGGCTGA CGGGATGCCG TCTGGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129305.2
CDS	78..527
Translation	MMMRVLFICVVSCLLVVNDGSIINRCTLARILYQEDLDGFEGYSLPHWLCLAFVESKFNISKVTENADGTFDYGIFQINSRYWCNDYQSHSENFCRLDCEELLNPNLIPSIHCAKMIVSGSGGMKNWVDWRLHCLGRPLSYWLTGCRLV

Target ORF information:

RefSeq Version	NM_001135833.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysozyme-like 6 (Lyzl6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135833.1

ORF Insert Sequence:

ATGATGATGA GGGTGCTGTT TATCTGTGTG GTGAGCTGCC TTCTGGTCGT GAATGATGGC 
AGCATCATCA ATCGCTGTAC CTTGGCCAGG ATTCTGTATC AAGAGGACTT GGATGGGTTT 
GAGGGCTACT CCCTGCCTCA CTGGCTGTGC TTGGCTTTTG TGGAGAGCAA ATTCAACATA 
TCAAAGGTGA CTGAGAATGC AGATGGTACC TTTGACTATG GAATCTTCCA GATCAATAGC 
CGTTACTGGT GCAATGACTA CCAGAGTCAT TCAGAGAACT TCTGCCGCCT GGACTGTGAA 
GAACTACTGA ATCCCAACCT CATTCCATCC ATCCACTGTG CAAAAATGAT TGTGTCTGGA 
TCTGGAGGGA TGAAGAACTG GGTAGATTGG AGGTTGCACT GTTTAGGACG GCCACTCTCC 
TACTGGCTGA CGGGATGCCG TCTGGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lyzl6 ( XM_006247503.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247565.1 Rattus norvegicus lysozyme-like 6 (Lyzl6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa04100
Clone ID Related Accession (Same CDS sequence)	XM_006247503.3 , NM_001135833.1
Accession Version	XM_006247503.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lysozyme-like protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247503.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGATGA GGGTGCTGTT TATCTGTGTG GTGAGCTGCC TTCTGGTCGT GAATGATGGC 
AGCATCATCA ATCGCTGTAC CTTGGCCAGG ATTCTGTATC AAGAGGACTT GGATGGGTTT 
GAGGGCTACT CCCTGCCTCA CTGGCTGTGC TTGGCTTTTG TGGAGAGCAA ATTCAACATA 
TCAAAGGTGA CTGAGAATGC AGATGGTACC TTTGACTATG GAATCTTCCA GATCAATAGC 
CGTTACTGGT GCAATGACTA CCAGAGTCAT TCAGAGAACT TCTGCCGCCT GGACTGTGAA 
GAACTACTGA ATCCCAACCT CATTCCATCC ATCCACTGTG CAAAAATGAT TGTGTCTGGA 
TCTGGAGGGA TGAAGAACTG GGTAGATTGG AGGTTGCACT GTTTAGGACG GCCACTCTCC 
TACTGGCTGA CGGGATGCCG TCTGGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247565.1
CDS	2104..2553
Translation	MMMRVLFICVVSCLLVVNDGSIINRCTLARILYQEDLDGFEGYSLPHWLCLAFVESKFNISKVTENADGTFDYGIFQINSRYWCNDYQSHSENFCRLDCEELLNPNLIPSIHCAKMIVSGSGGMKNWVDWRLHCLGRPLSYWLTGCRLV

Target ORF information:

RefSeq Version	XM_006247503.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysozyme-like 6 (Lyzl6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247503.3

ORF Insert Sequence:

ATGATGATGA GGGTGCTGTT TATCTGTGTG GTGAGCTGCC TTCTGGTCGT GAATGATGGC 
AGCATCATCA ATCGCTGTAC CTTGGCCAGG ATTCTGTATC AAGAGGACTT GGATGGGTTT 
GAGGGCTACT CCCTGCCTCA CTGGCTGTGC TTGGCTTTTG TGGAGAGCAA ATTCAACATA 
TCAAAGGTGA CTGAGAATGC AGATGGTACC TTTGACTATG GAATCTTCCA GATCAATAGC 
CGTTACTGGT GCAATGACTA CCAGAGTCAT TCAGAGAACT TCTGCCGCCT GGACTGTGAA 
GAACTACTGA ATCCCAACCT CATTCCATCC ATCCACTGTG CAAAAATGAT TGTGTCTGGA 
TCTGGAGGGA TGAAGAACTG GGTAGATTGG AGGTTGCACT GTTTAGGACG GCCACTCTCC 
TACTGGCTGA CGGGATGCCG TCTGGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LYZL6, an acidic, bacteriolytic, human sperm-related protein, plays a role in fertilization.
PloS one12(2)e0171452(2017)
Huang P,Li W,Yang Z,Zhang N,Xu Y,Bao J,Jiang D,Dong X

Immunization against lysozyme-like proteins affect sperm function and fertility in the rat.
Journal of reproductive immunology118100-108(2016 11)
Narmadha G,Yenugu S

Characterisation of Lyzls in mice and antibacterial properties of human LYZL6.
Asian journal of andrology15(6)824-30(2013 Nov)
Wei J,Li SJ,Shi H,Wang HY,Rong CT,Zhu P,Jin SH,Liu J,Li JY