Coasy cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Coasy
Entrez Gene ID	287711
Full Name	Coenzyme A synthase
General protein information	Preferred Names Coenzyme A synthase Names bifunctional coenzyme A synthase CoA synthase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31

mRNA and Protein(s)

mRNA	Protein	Name
XM_006247276.3	XP_006247338.1	bifunctional coenzyme A synthase isoform X1
NM_001006954.1	NP_001006955.1	bifunctional coenzyme A synthase precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	COASY	NP_001035997.2
Danio rerio (zebrafish)	coasy	NP_001004577.1
Arabidopsis thaliana (thale cress)	COAD	NP_179417.1
Canis lupus familiaris (dog)	COASY	XP_005624507.1
Drosophila melanogaster (fruit fly)	Ppat-Dpck	NP_647985.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005460	XP_315463.3
Oryza sativa (rice)	Os07g0179400	NP_001059035.1
Mus musculus (house mouse)	Coasy	NP_082172.2
Pan troglodytes (chimpanzee)	COASY	XP_001163322.2
	COASY	XP_001110129.2
Bos taurus (cattle)	COASY	XP_005220858.1
Rattus norvegicus (Norway rat)	Coasy	NP_001006955.1
Caenorhabditis elegans (roundworm)	Y65B4A.8	NP_490766.2
Xenopus tropicalis (tropical clawed frog)	coasy	XP_002942317.1

Gene Ontology
Bibliography

Related articles in PubMed

Exome sequence reveals mutations in CoA synthase as a cause of neurodegeneration with brain iron accumulation.
Dusi S, Valletta L, Haack TB, Tsuchiya Y, Venco P, Pasqualato S, Goffrini P, Tigano M, Demchenko N, Wieland T, Schwarzmayr T, Strom TM, Invernizzi F, Garavaglia B, Gregory A, Sanford L, Hamada J, Bettencourt C, Houlden H, Chiapparini L, Zorzi G, Kurian MA, Nardocci N, Prokisch H, Hayflick S, Gout I, Tiranti V
American journal of human genetics94(1)11-22(2014 Jan)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

Identification of a novel CoA synthase isoform, which is primarily expressed in the brain.
Nemazanyy I, Panasyuk G, Breus O, Zhyvoloup A, Filonenko V, Gout IT
Biochemical and biophysical research communications341(4)995-1000(2006 Mar)

Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism.
Nemazanyy I, Panasyuk G, Zhyvoloup A, Panayotou G, Gout IT, Filonenko V
FEBS letters578(3)357-62(2004 Dec)

Identification and characterization of the gene encoding the human phosphopantetheine adenylyltransferase and dephospho-CoA kinase bifunctional enzyme (CoA synthase).
Aghajanian S, Worrall DM
The Biochemical journal365(Pt 1)13-8(2002 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

description of the existence of a novel CoA synthase isoform, which is the product of alternative splicing and possesses a 29aa extension at the N-terminus; isoform is termed CoASy beta.
Title: Identification of a novel CoA synthase isoform, which is primarily expressed in the brain.

The following Coasy gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Coasy cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10889	NM_001006954.1 Latest version!	Rattus norvegicus Coenzyme A synthase (Coasy), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa10889	XM_006247276.3 Latest version!	Rattus norvegicus Coenzyme A synthase (Coasy), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Coasy ( NM_001006954.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001006955.1 Rattus norvegicus Coenzyme A synthase (Coasy), mRNA.

Price & Availability↑

CloneID	ORa10889
Clone ID Related Accession (Same CDS sequence)	XM_006247276.3 , NM_001006954.1
Accession Version	NM_001006954.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-26
Organism	Rattus norvegicus(Norway rat)
Product	bifunctional coenzyme A synthase precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083781.1. On Nov 22, 2004 this sequence version replaced XM_213464.2. ##Evidence-Data-START## Transcript exon combination :: BC083781.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGCCGTAT TCCGCTCAGG CCTCCTGGTG CTGACAACGC CGCTGGCCAC CCTGGCCGCA 
CGCCTGCCTC CCATCCTGAC CTCGGCGTCA CACCTGGTGA ATCACACCCT CTATGTGCAC 
CTGCAGCCGG GCATGAACCT GGGGGGACCC GCTCAGCCCC AGCCCAGCCC TGTGCAGGCC 
ACATTTGAGG TTCTGGATTT CATCACGCAC CTCTACACTG GTGCCGACCT GCACAGGCAC 
CTGGACGTCA GAATTCTACT GACCAATATC CAAACCAAGA GTACCTTAAT CCCTGTGCTT 
TCCTCAGTCC AGAATCTGGC CCACCCTCCA GAAGTAGTTC TGACGGACTT CCAGACCCTG 
GATGGGAGCC AGTACAACCC TGTTAAACAA CAGCTAGAGC GTTATGCCAC CAGCTGCTAC 
AGCTGTTCTC CACAGTTGTC TTCCGTATTG CTGTATCCGG ATTATGGGAC TGGAGAGATG 
CCTTTGGAAC TCCCGAATGC CCTCTTACCC TCCACCATAA GGCCAGCTTC CCCGGTGGCC 
AGATCTCCGA GGCAGCCTGT GCGTGGCTAC CGCCGTGGGG CCGTGGGTGG CACTTTTGAC 
CGCTTGCACA ATGCCCACAA AGTGTTGCTC AGTGTTGCAT GTGTACTGGC CCAGGAGCAG 
CTTGTGGTGG GAGTAGCGGA CAAAGATCTG TTGAAGAGCA AGTTGCTCCC TGAGCTGCTC 
CAGCCTTATT CAGAGCGTGT GGGGCATCTG AATGAGTTCC TGGTGGACAT CAAGCCCTCC 
CTGACTTTTG AACTCATCCC CCTGCTGGAT CCCTATGGGC CTGCTGGGTC TGACCCCACT 
TTGGAGTTCC TGGTGGTCAG CGAGGAGACC TACCGTGGGG GGATGGCCGT CAACCGCTTC 
CGCCTTGAGA ATGGCAAAGA GGAGCTCGCC TTATACCAGA TACAGCTGCT GAAGGACCAG 
AGTCACAAGG AAAACGAGGA GGAAAAGGTC AGCTCCTCCA GCTTTCGCCA GCGAATTCTG 
GGAAACCTGC TTCAGCCTCC GAATGAGAGG CCCGAGCTCC CGTCAGGTAT CTATGTGCTG 
GGGCTGACAG GCATCAGCGG CTCTGGGAAA AGCTCAGTGG CTCAGCGGCT GAAGAACTTG 
GGGGCATACA TCATTGACAG TGACCATCTG GGCCACCGGG CCTATGCTCC CGGGGGCCCT 
GCCTACCAGC CTGTGGTGGA GGCCTTTGGA ACAGATATTC TCCATCAAGA TGGGACCATC 
AATAGGAAGG TCCTAGGCAG CCGGGTGTTT GGGAATAAGA AGCAGCTGAA GATGCTCACA 
GATATTGTGT GGCCAGTTAT CGCAAAGCTG GCCCGAGAGG AGATGGATGT GGCTGTGGCT 
AAGGGAAAGA CTCTGTGTGT GATTGATGCT GCTATGCTGC TTGAAGCTGG CTGGCAGAAT 
ATGGTACACG AGGTGTGGAC CGTCGTCATC CCTGAGTCTG AGGCTGTACG TCGCATTGTT 
GAGAGGGATG GACTGAGTGA GGCAGCCGCT CAAAGCCGGC TGCAGAACCA GATGAGTGGG 
CAGCAGCTGG TAGAGCAGAG CCACGTGGTT CTGTGCACCT TGTGGGAATC ACATGTCACA 
CAGCGCCAGG TGGAAAAGGC TTGGGATCTT CTACAGAAAC GCCTCCCCAA GGCTCACCAG 
ACCAGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001006955.1
CDS	27..1718
Translation	MAVFRSGLLVLTTPLATLAARLPPILTSASHLVNHTLYVHLQPGMNLGGPAQPQPSPVQATFEVLDFITHLYTGADLHRHLDVRILLTNIQTKSTLIPVLSSVQNLAHPPEVVLTDFQTLDGSQYNPVKQQLERYATSCYSCSPQLSSVLLYPDYGTGEMPLELPNALLPSTIRPASPVARSPRQPVRGYRRGAVGGTFDRLHNAHKVLLSVACVLAQEQLVVGVADKDLLKSKLLPELLQPYSERVGHLNEFLVDIKPSLTFELIPLLDPYGPAGSDPTLEFLVVSEETYRGGMAVNRFRLENGKEELALYQIQLLKDQSHKENEEEKVSSSSFRQRILGNLLQPPNERPELPSGIYVLGLTGISGSGKSSVAQRLKNLGAYIIDSDHLGHRAYAPGGPAYQPVVEAFGTDILHQDGTINRKVLGSRVFGNKKQLKMLTDIVWPVIAKLAREEMDVAVAKGKTLCVIDAAMLLEAGWQNMVHEVWTVVIPESEAVRRIVERDGLSEAAAQSRLQNQMSGQQLVEQSHVVLCTLWESHVTQRQVEKAWDLLQKRLPKAHQTRN

Target ORF information:

RefSeq Version	NM_001006954.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Coenzyme A synthase (Coasy), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001006954.1

ORF Insert Sequence:

ATGGCCGTAT TCCGCTCAGG CCTCCTGGTG CTGACAACGC CGCTGGCCAC CCTGGCCGCA 
CGCCTGCCTC CCATCCTGAC CTCGGCGTCA CACCTGGTGA ATCACACCCT CTATGTGCAC 
CTGCAGCCGG GCATGAACCT GGGGGGACCC GCTCAGCCCC AGCCCAGCCC TGTGCAGGCC 
ACATTTGAGG TTCTGGATTT CATCACGCAC CTCTACACTG GTGCCGACCT GCACAGGCAC 
CTGGACGTCA GAATTCTACT GACCAATATC CAAACCAAGA GTACCTTAAT CCCTGTGCTT 
TCCTCAGTCC AGAATCTGGC CCACCCTCCA GAAGTAGTTC TGACGGACTT CCAGACCCTG 
GATGGGAGCC AGTACAACCC TGTTAAACAA CAGCTAGAGC GTTATGCCAC CAGCTGCTAC 
AGCTGTTCTC CACAGTTGTC TTCCGTATTG CTGTATCCGG ATTATGGGAC TGGAGAGATG 
CCTTTGGAAC TCCCGAATGC CCTCTTACCC TCCACCATAA GGCCAGCTTC CCCGGTGGCC 
AGATCTCCGA GGCAGCCTGT GCGTGGCTAC CGCCGTGGGG CCGTGGGTGG CACTTTTGAC 
CGCTTGCACA ATGCCCACAA AGTGTTGCTC AGTGTTGCAT GTGTACTGGC CCAGGAGCAG 
CTTGTGGTGG GAGTAGCGGA CAAAGATCTG TTGAAGAGCA AGTTGCTCCC TGAGCTGCTC 
CAGCCTTATT CAGAGCGTGT GGGGCATCTG AATGAGTTCC TGGTGGACAT CAAGCCCTCC 
CTGACTTTTG AACTCATCCC CCTGCTGGAT CCCTATGGGC CTGCTGGGTC TGACCCCACT 
TTGGAGTTCC TGGTGGTCAG CGAGGAGACC TACCGTGGGG GGATGGCCGT CAACCGCTTC 
CGCCTTGAGA ATGGCAAAGA GGAGCTCGCC TTATACCAGA TACAGCTGCT GAAGGACCAG 
AGTCACAAGG AAAACGAGGA GGAAAAGGTC AGCTCCTCCA GCTTTCGCCA GCGAATTCTG 
GGAAACCTGC TTCAGCCTCC GAATGAGAGG CCCGAGCTCC CGTCAGGTAT CTATGTGCTG 
GGGCTGACAG GCATCAGCGG CTCTGGGAAA AGCTCAGTGG CTCAGCGGCT GAAGAACTTG 
GGGGCATACA TCATTGACAG TGACCATCTG GGCCACCGGG CCTATGCTCC CGGGGGCCCT 
GCCTACCAGC CTGTGGTGGA GGCCTTTGGA ACAGATATTC TCCATCAAGA TGGGACCATC 
AATAGGAAGG TCCTAGGCAG CCGGGTGTTT GGGAATAAGA AGCAGCTGAA GATGCTCACA 
GATATTGTGT GGCCAGTTAT CGCAAAGCTG GCCCGAGAGG AGATGGATGT GGCTGTGGCT 
AAGGGAAAGA CTCTGTGTGT GATTGATGCT GCTATGCTGC TTGAAGCTGG CTGGCAGAAT 
ATGGTACACG AGGTGTGGAC CGTCGTCATC CCTGAGTCTG AGGCTGTACG TCGCATTGTT 
GAGAGGGATG GACTGAGTGA GGCAGCCGCT CAAAGCCGGC TGCAGAACCA GATGAGTGGG 
CAGCAGCTGG TAGAGCAGAG CCACGTGGTT CTGTGCACCT TGTGGGAATC ACATGTCACA 
CAGCGCCAGG TGGAAAAGGC TTGGGATCTT CTACAGAAAC GCCTCCCCAA GGCTCACCAG 
ACCAGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Coasy ( XM_006247276.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247338.1 Rattus norvegicus Coenzyme A synthase (Coasy), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa10889
Clone ID Related Accession (Same CDS sequence)	XM_006247276.3 , NM_001006954.1
Accession Version	XM_006247276.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	bifunctional coenzyme A synthase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247276.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGTAT TCCGCTCAGG CCTCCTGGTG CTGACAACGC CGCTGGCCAC CCTGGCCGCA 
CGCCTGCCTC CCATCCTGAC CTCGGCGTCA CACCTGGTGA ATCACACCCT CTATGTGCAC 
CTGCAGCCGG GCATGAACCT GGGGGGACCC GCTCAGCCCC AGCCCAGCCC TGTGCAGGCC 
ACATTTGAGG TTCTGGATTT CATCACGCAC CTCTACACTG GTGCCGACCT GCACAGGCAC 
CTGGACGTCA GAATTCTACT GACCAATATC CAAACCAAGA GTACCTTAAT CCCTGTGCTT 
TCCTCAGTCC AGAATCTGGC CCACCCTCCA GAAGTAGTTC TGACGGACTT CCAGACCCTG 
GATGGGAGCC AGTACAACCC TGTTAAACAA CAGCTAGAGC GTTATGCCAC CAGCTGCTAC 
AGCTGTTCTC CACAGTTGTC TTCCGTATTG CTGTATCCGG ATTATGGGAC TGGAGAGATG 
CCTTTGGAAC TCCCGAATGC CCTCTTACCC TCCACCATAA GGCCAGCTTC CCCGGTGGCC 
AGATCTCCGA GGCAGCCTGT GCGTGGCTAC CGCCGTGGGG CCGTGGGTGG CACTTTTGAC 
CGCTTGCACA ATGCCCACAA AGTGTTGCTC AGTGTTGCAT GTGTACTGGC CCAGGAGCAG 
CTTGTGGTGG GAGTAGCGGA CAAAGATCTG TTGAAGAGCA AGTTGCTCCC TGAGCTGCTC 
CAGCCTTATT CAGAGCGTGT GGGGCATCTG AATGAGTTCC TGGTGGACAT CAAGCCCTCC 
CTGACTTTTG AACTCATCCC CCTGCTGGAT CCCTATGGGC CTGCTGGGTC TGACCCCACT 
TTGGAGTTCC TGGTGGTCAG CGAGGAGACC TACCGTGGGG GGATGGCCGT CAACCGCTTC 
CGCCTTGAGA ATGGCAAAGA GGAGCTCGCC TTATACCAGA TACAGCTGCT GAAGGACCAG 
AGTCACAAGG AAAACGAGGA GGAAAAGGTC AGCTCCTCCA GCTTTCGCCA GCGAATTCTG 
GGAAACCTGC TTCAGCCTCC GAATGAGAGG CCCGAGCTCC CGTCAGGTAT CTATGTGCTG 
GGGCTGACAG GCATCAGCGG CTCTGGGAAA AGCTCAGTGG CTCAGCGGCT GAAGAACTTG 
GGGGCATACA TCATTGACAG TGACCATCTG GGCCACCGGG CCTATGCTCC CGGGGGCCCT 
GCCTACCAGC CTGTGGTGGA GGCCTTTGGA ACAGATATTC TCCATCAAGA TGGGACCATC 
AATAGGAAGG TCCTAGGCAG CCGGGTGTTT GGGAATAAGA AGCAGCTGAA GATGCTCACA 
GATATTGTGT GGCCAGTTAT CGCAAAGCTG GCCCGAGAGG AGATGGATGT GGCTGTGGCT 
AAGGGAAAGA CTCTGTGTGT GATTGATGCT GCTATGCTGC TTGAAGCTGG CTGGCAGAAT 
ATGGTACACG AGGTGTGGAC CGTCGTCATC CCTGAGTCTG AGGCTGTACG TCGCATTGTT 
GAGAGGGATG GACTGAGTGA GGCAGCCGCT CAAAGCCGGC TGCAGAACCA GATGAGTGGG 
CAGCAGCTGG TAGAGCAGAG CCACGTGGTT CTGTGCACCT TGTGGGAATC ACATGTCACA 
CAGCGCCAGG TGGAAAAGGC TTGGGATCTT CTACAGAAAC GCCTCCCCAA GGCTCACCAG 
ACCAGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247338.1
CDS	410..2101
Translation	MAVFRSGLLVLTTPLATLAARLPPILTSASHLVNHTLYVHLQPGMNLGGPAQPQPSPVQATFEVLDFITHLYTGADLHRHLDVRILLTNIQTKSTLIPVLSSVQNLAHPPEVVLTDFQTLDGSQYNPVKQQLERYATSCYSCSPQLSSVLLYPDYGTGEMPLELPNALLPSTIRPASPVARSPRQPVRGYRRGAVGGTFDRLHNAHKVLLSVACVLAQEQLVVGVADKDLLKSKLLPELLQPYSERVGHLNEFLVDIKPSLTFELIPLLDPYGPAGSDPTLEFLVVSEETYRGGMAVNRFRLENGKEELALYQIQLLKDQSHKENEEEKVSSSSFRQRILGNLLQPPNERPELPSGIYVLGLTGISGSGKSSVAQRLKNLGAYIIDSDHLGHRAYAPGGPAYQPVVEAFGTDILHQDGTINRKVLGSRVFGNKKQLKMLTDIVWPVIAKLAREEMDVAVAKGKTLCVIDAAMLLEAGWQNMVHEVWTVVIPESEAVRRIVERDGLSEAAAQSRLQNQMSGQQLVEQSHVVLCTLWESHVTQRQVEKAWDLLQKRLPKAHQTRN

Target ORF information:

RefSeq Version	XM_006247276.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Coenzyme A synthase (Coasy), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247276.3

ORF Insert Sequence:

ATGGCCGTAT TCCGCTCAGG CCTCCTGGTG CTGACAACGC CGCTGGCCAC CCTGGCCGCA 
CGCCTGCCTC CCATCCTGAC CTCGGCGTCA CACCTGGTGA ATCACACCCT CTATGTGCAC 
CTGCAGCCGG GCATGAACCT GGGGGGACCC GCTCAGCCCC AGCCCAGCCC TGTGCAGGCC 
ACATTTGAGG TTCTGGATTT CATCACGCAC CTCTACACTG GTGCCGACCT GCACAGGCAC 
CTGGACGTCA GAATTCTACT GACCAATATC CAAACCAAGA GTACCTTAAT CCCTGTGCTT 
TCCTCAGTCC AGAATCTGGC CCACCCTCCA GAAGTAGTTC TGACGGACTT CCAGACCCTG 
GATGGGAGCC AGTACAACCC TGTTAAACAA CAGCTAGAGC GTTATGCCAC CAGCTGCTAC 
AGCTGTTCTC CACAGTTGTC TTCCGTATTG CTGTATCCGG ATTATGGGAC TGGAGAGATG 
CCTTTGGAAC TCCCGAATGC CCTCTTACCC TCCACCATAA GGCCAGCTTC CCCGGTGGCC 
AGATCTCCGA GGCAGCCTGT GCGTGGCTAC CGCCGTGGGG CCGTGGGTGG CACTTTTGAC 
CGCTTGCACA ATGCCCACAA AGTGTTGCTC AGTGTTGCAT GTGTACTGGC CCAGGAGCAG 
CTTGTGGTGG GAGTAGCGGA CAAAGATCTG TTGAAGAGCA AGTTGCTCCC TGAGCTGCTC 
CAGCCTTATT CAGAGCGTGT GGGGCATCTG AATGAGTTCC TGGTGGACAT CAAGCCCTCC 
CTGACTTTTG AACTCATCCC CCTGCTGGAT CCCTATGGGC CTGCTGGGTC TGACCCCACT 
TTGGAGTTCC TGGTGGTCAG CGAGGAGACC TACCGTGGGG GGATGGCCGT CAACCGCTTC 
CGCCTTGAGA ATGGCAAAGA GGAGCTCGCC TTATACCAGA TACAGCTGCT GAAGGACCAG 
AGTCACAAGG AAAACGAGGA GGAAAAGGTC AGCTCCTCCA GCTTTCGCCA GCGAATTCTG 
GGAAACCTGC TTCAGCCTCC GAATGAGAGG CCCGAGCTCC CGTCAGGTAT CTATGTGCTG 
GGGCTGACAG GCATCAGCGG CTCTGGGAAA AGCTCAGTGG CTCAGCGGCT GAAGAACTTG 
GGGGCATACA TCATTGACAG TGACCATCTG GGCCACCGGG CCTATGCTCC CGGGGGCCCT 
GCCTACCAGC CTGTGGTGGA GGCCTTTGGA ACAGATATTC TCCATCAAGA TGGGACCATC 
AATAGGAAGG TCCTAGGCAG CCGGGTGTTT GGGAATAAGA AGCAGCTGAA GATGCTCACA 
GATATTGTGT GGCCAGTTAT CGCAAAGCTG GCCCGAGAGG AGATGGATGT GGCTGTGGCT 
AAGGGAAAGA CTCTGTGTGT GATTGATGCT GCTATGCTGC TTGAAGCTGG CTGGCAGAAT 
ATGGTACACG AGGTGTGGAC CGTCGTCATC CCTGAGTCTG AGGCTGTACG TCGCATTGTT 
GAGAGGGATG GACTGAGTGA GGCAGCCGCT CAAAGCCGGC TGCAGAACCA GATGAGTGGG 
CAGCAGCTGG TAGAGCAGAG CCACGTGGTT CTGTGCACCT TGTGGGAATC ACATGTCACA 
CAGCGCCAGG TGGAAAAGGC TTGGGATCTT CTACAGAAAC GCCTCCCCAA GGCTCACCAG 
ACCAGGAACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exome sequence reveals mutations in CoA synthase as a cause of neurodegeneration with brain iron accumulation.
American journal of human genetics94(1)11-22(2014 Jan)
Dusi S,Valletta L,Haack TB,Tsuchiya Y,Venco P,Pasqualato S,Goffrini P,Tigano M,Demchenko N,Wieland T,Schwarzmayr T,Strom TM,Invernizzi F,Garavaglia B,Gregory A,Sanford L,Hamada J,Bettencourt C,Houlden H,Chiapparini L,Zorzi G,Kurian MA,Nardocci N,Prokisch H,Hayflick S,Gout I,Tiranti V

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

Identification of a novel CoA synthase isoform, which is primarily expressed in the brain.
Biochemical and biophysical research communications341(4)995-1000(2006 Mar)
Nemazanyy I,Panasyuk G,Breus O,Zhyvoloup A,Filonenko V,Gout IT

Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism.
FEBS letters578(3)357-62(2004 Dec)
Nemazanyy I,Panasyuk G,Zhyvoloup A,Panayotou G,Gout IT,Filonenko V

Identification and characterization of the gene encoding the human phosphopantetheine adenylyltransferase and dephospho-CoA kinase bifunctional enzyme (CoA synthase).
The Biochemical journal365(Pt 1)13-8(2002 Jul)
Aghajanian S,Worrall DM