Eif1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif1
Entrez Gene ID	287703
Full Name	eukaryotic translation initiation factor 1
Synonyms	Sui1-rs1
General protein information	Preferred Names eukaryotic translation initiation factor 1 Names eukaryotic translation initiation factor 1 suppressor of initiator codon mutations, related sequence 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31

mRNA and Protein(s)

mRNA	Protein	Name
NM_001105837.1	NP_001099307.1	eukaryotic translation initiation factor 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Eif1	NP_035638.1
Saccharomyces cerevisiae (baker's yeast)	SUI1	NP_014155.1
Rattus norvegicus (Norway rat)	Eif1	NP_001099307.1
Drosophila melanogaster (fruit fly)	CG17737	NP_647792.1
Neurospora crassa	NCU01981	XP_964345.2
Kluyveromyces lactis	KLLA0C03091g	XP_452335.1
Eremothecium gossypii	AGOS_ADL395C	NP_983701.1
Schizosaccharomyces pombe (fission yeast)	sui1	NP_595863.1
Caenorhabditis elegans (roundworm)	eif-1	NP_001254096.1
Eremothecium gossypii	AGOS_AER457W	NP_985312.1
Eremothecium gossypii	AGOS_AFR642C	NP_986189.2
Eremothecium gossypii	AGOS_AFR752W	XP_002999503.1
Magnaporthe oryzae (rice blast fungus)	MGG_13474	XP_003716163.1
Pan troglodytes (chimpanzee)	LOC735805	XP_003953324.1
Anopheles gambiae (African malaria mosquito)	SUI1_ANOGA	XP_316499.2
Arabidopsis thaliana (thale cress)	AT5G54940	NP_568818.1

Gene Ontology
Bibliography

Related articles in PubMed

The scanning mechanism of eukaryotic translation initiation.
Hinnebusch AG
Annual review of biochemistry83779-812(2014)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5.
Loughran G, Sachs MS, Atkins JF, Ivanov IP
Nucleic acids research40(7)2898-906(2012 Apr)

Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation.
Ciaudo C, Bourdet A, Cohen-Tannoudji M, Dietz HC, Rougeulle C, Avner P
PLoS genetics2(6)e94(2006 Jun)

Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.
Bohnsack MT, Regener K, Schwappach B, Saffrich R, Paraskeva E, Hartmann E, G?rlich D
The EMBO journal21(22)6205-15(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eif1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11508	NM_001105837.1 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 1 (Eif1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif1 ( NM_001105837.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099307.1 Rattus norvegicus eukaryotic translation initiation factor 1 (Eif1), mRNA.

Price & Availability↑

CloneID	ORa11508
Clone ID Related Accession (Same CDS sequence)	NM_001105837.1
Accession Version	NM_001105837.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 3, 2007 this sequence version replaced XM_213456.4, XM_001081454.1. ##Evidence-Data-START## Transcript exon combination :: FQ212688.1, BC159406.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCCGCTA TCCAGAACCT CCACTCTTTC GACCCCTTTG CTGATGCAAG TAAGGGTGAT 
GACCTGCTTC CTGCTGGCAC TGAGGATTAT ATCCATATAA GAATTCAACA GAGAAACGGC 
AGGAAGACCC TTACAACTGT CCAAGGGATC GCTGATGATT ACGATAAAAA GAAACTAGTG 
AAGGCGTTTA AGAAGAAATT TGCCTGCAAT GGTACTGTAA TTGAGCATCC AGAATATGGA 
GAAGTAATTC AGCTACAGGG TGACCAGCGC AAGAACATAT GCCAGTTCCT GATAGAGATT 
GGACTGGCTA AGGACGATCA GCTGAAGGTT CATGGGTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099307.1
CDS	148..489
Translation	MSAIQNLHSFDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF

Target ORF information:

RefSeq Version	NM_001105837.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 1 (Eif1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105837.1

ORF Insert Sequence:

ATGTCCGCTA TCCAGAACCT CCACTCTTTC GACCCCTTTG CTGATGCAAG TAAGGGTGAT 
GACCTGCTTC CTGCTGGCAC TGAGGATTAT ATCCATATAA GAATTCAACA GAGAAACGGC 
AGGAAGACCC TTACAACTGT CCAAGGGATC GCTGATGATT ACGATAAAAA GAAACTAGTG 
AAGGCGTTTA AGAAGAAATT TGCCTGCAAT GGTACTGTAA TTGAGCATCC AGAATATGGA 
GAAGTAATTC AGCTACAGGG TGACCAGCGC AAGAACATAT GCCAGTTCCT GATAGAGATT 
GGACTGGCTA AGGACGATCA GCTGAAGGTT CATGGGTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The scanning mechanism of eukaryotic translation initiation.
Annual review of biochemistry83779-812(2014)
Hinnebusch AG

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5.
Nucleic acids research40(7)2898-906(2012 Apr)
Loughran G,Sachs MS,Atkins JF,Ivanov IP

Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation.
PLoS genetics2(6)e94(2006 Jun)
Ciaudo C,Bourdet A,Cohen-Tannoudji M,Dietz HC,Rougeulle C,Avner P

Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.
The EMBO journal21(22)6205-15(2002 Nov)
Bohnsack MT,Regener K,Schwappach B,Saffrich R,Paraskeva E,Hartmann E,G?rlich D