Aloxe3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Aloxe3
Entrez Gene ID	287424
Full Name	arachidonate lipoxygenase 3
Synonyms	e-LOX-3,eLOX-3
General protein information	Preferred Names arachidonate lipoxygenase 3 Names hydroperoxide isomerase ALOXE3 epidermal LOX-3 epidermis-type lipoxygenase 3 hydroperoxy icosatetraenoate dehydratase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24

mRNA and Protein(s)

mRNA	Protein	Name
XM_017597088.1	XP_017452577.1	hydroperoxide isomerase ALOXE3 isoform X1
XM_017597089.1	XP_017452578.1	hydroperoxide isomerase ALOXE3 isoform X2
XM_006246619.2	XP_006246681.1	hydroperoxide isomerase ALOXE3 isoform X1
XM_017597087.1	XP_017452576.1	hydroperoxide isomerase ALOXE3 isoform X1
NM_001105793.1	NP_001099263.1	hydroperoxide isomerase ALOXE3

Pathways from BioSystems

Homologies

Homo sapiens (human)	ALOXE3	NP_001159432.1
Rattus norvegicus (Norway rat)	Aloxe3	NP_001099263.1
Xenopus tropicalis (tropical clawed frog)	alox12b	NP_001015741.1
Xenopus tropicalis (tropical clawed frog)	LOC100494678	XP_002943034.2
Canis lupus familiaris (dog)	ALOXE3	XP_005620066.1
Danio rerio (zebrafish)	si:dkey-17e16.9	XP_001334034.2
Danio rerio (zebrafish)	LOC100534703	XP_003200885.2
Xenopus tropicalis (tropical clawed frog)	LOC100494252	XP_002943031.1
Pan troglodytes (chimpanzee)	ALOXE3	XP_003315697.1
	LOC716840	XP_002808161.1
Bos taurus (cattle)	ALOXE3	XP_003587465.2
Mus musculus (house mouse)	Aloxe3	NP_035916.2
Xenopus tropicalis (tropical clawed frog)	aloxe3	XP_002943378.1
Xenopus tropicalis (tropical clawed frog)	LOC100494416	XP_002943032.1

Gene Ontology
Bibliography

Related articles in PubMed

Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia.
Gregus AM, Dumlao DS, Wei SC, Norris PC, Catella LC, Meyerstein FG, Buczynski MW, Steinauer JJ, Fitzsimmons BL, Yaksh TL, Dennis EA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology27(5)1939-49(2013 May)

Role of tomato lipoxygenase D in wound-induced jasmonate biosynthesis and plant immunity to insect herbivores.
Yan L, Zhai Q, Wei J, Li S, Wang B, Huang T, Du M, Sun J, Kang L, Li CB, Li C
PLoS genetics9(12)e1003964(2013)

Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation.
Krieg P, Rosenberger S, de Juanes S, Latzko S, Hou J, Dick A, Kloz U, van der Hoeven F, Hausser I, Esposito I, Rauh M, Schneider H
The Journal of investigative dermatology133(1)172-80(2013 Jan)

Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope.
Zheng Y, Yin H, Boeglin WE, Elias PM, Crumrine D, Beier DR, Brash AR
The Journal of biological chemistry286(27)24046-56(2011 Jul)

Dioxygenase activity of epidermal lipoxygenase-3 unveiled: typical and atypical features of its catalytic activity with natural and synthetic polyunsaturated fatty acids.
Zheng Y, Brash AR
The Journal of biological chemistry285(51)39866-75(2010 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Aloxe3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Aloxe3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11426	NM_001105793.1 Latest version!	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa33248	XM_017597088.1 Latest version!	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa33248	XM_006246619.2 Latest version!	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa33248	XM_017597087.1 Latest version!	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa57220	XM_017597089.1 Latest version!	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Aloxe3 ( NM_001105793.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099263.1 Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), mRNA.

Price & Availability↑

CloneID	ORa11426
Clone ID Related Accession (Same CDS sequence)	NM_001105793.1
Accession Version	NM_001105793.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	hydroperoxide isomerase ALOXE3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 3, 2007 this sequence version replaced XM_213336.4, XM_001078483.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGTAT ATCGCCTGTG TGTGACCACT GGTTCCTACC TGAAGGCTGG CACATTGGAT 
AACATCTATG CTACACTGGT AGGCACCTGT GGTGAAAGCC CTAAGCAGAA GCTGGATCGT 
GTAGGCAGGG ACTTCGCCAC CGGATCGGTT CAGAAGTACA AGGTGCGCTG TGCATCAGAG 
CTGGGTGAGA TCTTGCTGTT GCGCTTACAC AAGGAGCGCT TTGCTTTCTT CTGCAAGGAT 
CCTTGGTACT GCAGTCGCAT CTGTGTCACT ACCCCAGATG GCTCTGTGGT TCACTTTCCC 
TGTTATCAGT GGATCGATGG CTACTGTACT GTGGAGCTTC GGCCAGGAAC AGCAAGAACC 
ATCTGCCAGG ATGCTCTTCC CCTCCTTCTG GATCACAGGA AGCGTGAACT CCAAGCCCGC 
CAAGAATGCT ACCGCTGGAA GATCTATGCC CCTGGTTTCC CTCGAATGGT GGATGTCAGC 
AGCTTTGAGG AGATGGAGTC AGATAAGAAA TTTGCCTTGA CCAAGACGGC GCCTTGTGCA 
GACCAGGATG ATAACTCTGG GAACCGGTAC CTGCCTGGCT TTCCTATGAA AGTTGACATC 
CCATCTCTGC TGCACATGGA GCCCAACATT CGCTACTCAG CCACCAAGAC AGCCTCACTC 
ATCTTCAACG CCCTTCCTGC ATCCTTGGGC ATGAAGATTC GAGGTCTGCT AGACCGCAAG 
GGCTCCTGGA AGAGGCTGGA TGACATCCGG AACATCTTCT GGTGTCATAA GACCTTCACT 
TCAGAGTATG TCACCGAGCA CTGGTGTGAG GACAGCTTCT TTGGGTACCA GTACCTGAAC 
GGTGTCAATC CCATCATGCT CCACTGCCTC TCCAGTCTGC CCAGCAAGCT GCCTGTCACC 
AATGACATGG TGGCACCTTT GCTGGGACCC GGCACCTGCC TGCAAACAGA GCTAGAGAGG 
GGGCACATCT TCTTAGCGGA CTACTGGATC CTGGCGGAGG CCCCAGTCCA TTGCCTAAAC 
GGCCGCCAAC AGTACGTAAC AGCTCCTCTC TGCCTGTTAT GGCTCAACCC ACAGGGGGTG 
CTGCTGCCGT TGGCAATCCA GCTCAGCCAG ATACCAGGGC CAGAGAGCCC CATCTTTCTA 
CCCACTGACT GCGAGTTGGA TTGGCTGCTG GCCAAGACGT GGGTGCGCAA CTCTGAGTTT 
TTGGTGCATG AGAACAACAC GCATTTTCTG TGCACGCATT TGCTCTGCGA GGCCTTCTCC 
ATGGCTACAC TGCGTCAGCT GCCCCTCTGT CATCCAGTCT ACAAGCTCCT GCTTCCTCAC 
ACTCGCTACA CACTGCAAGT GAACACCATC GCAAGGGCCA CACTGCTCAA CCCAGACGGC 
CTCGTGGACA AGGTCACATC CATCGGTAGG CGCGGCCTCA TCTACCTCAT GAGCACAGGG 
CTGGCCCACT TCACCTACAC GGATTTCTGC CTTCCGGATA GCCTACGGGC TCGTGGTGTC 
CTGACCATTC CCAACTACCA CTACCGAGAC GACGGCCTCA AGATCTGGGC GGCTATTGAG 
AGGTTTGTCT CCGAGATTGT GAGTTACTAT TACCCCAACG ATGCCTGTGT GCAGCAGGAC 
TCTGAGCTGC AGGCCTGGGT GGGTGAGATT TTTGCTCAGG CATTCCTCGG TCGGGAGAGT 
TCAGGCTTCC CAAGCAGGCT GTGCACCCCA GGAGAGCTCG TGAAGTATCT CACTGCAATC 
ATCTTTAACT GCTCCGCCCA GCACGCTGCA GTCAACAGTG GGCAGCACGA CTTTGGGGCC 
TGGATGCCCA ATGCCCCGTC ATCCATGAGG CAGCCTCCAC CTCAGACCAA GGGCAACACG 
ACAATGGAGA GTTACCTCGA AACCCTCCCA GAGGTGAACA CCACCTGTAG CAACCTTCTC 
CTCTTCTGGC TGGTCAGCCA AGAGCCAAAG GACCAGAGGC CTCTGGGCAC CTACCCAGAC 
GAACACTTCA CAGAGGAGGC CCCACGGCAA AGCATCGCAG CCTTCCAGAA GTGCCTGGCA 
CAGATCTCAA AGGACATCAG GGCACGCAAC GAGAGCCTGG CACTACCCTA TGCCTACTTG 
GATCCACCAC TCATTGAGAA CAGTGTCTCC ATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099263.1
CDS	27..2162
Translation	MAVYRLCVTTGSYLKAGTLDNIYATLVGTCGESPKQKLDRVGRDFATGSVQKYKVRCASELGEILLLRLHKERFAFFCKDPWYCSRICVTTPDGSVVHFPCYQWIDGYCTVELRPGTARTICQDALPLLLDHRKRELQARQECYRWKIYAPGFPRMVDVSSFEEMESDKKFALTKTAPCADQDDNSGNRYLPGFPMKVDIPSLLHMEPNIRYSATKTASLIFNALPASLGMKIRGLLDRKGSWKRLDDIRNIFWCHKTFTSEYVTEHWCEDSFFGYQYLNGVNPIMLHCLSSLPSKLPVTNDMVAPLLGPGTCLQTELERGHIFLADYWILAEAPVHCLNGRQQYVTAPLCLLWLNPQGVLLPLAIQLSQIPGPESPIFLPTDCELDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFSMATLRQLPLCHPVYKLLLPHTRYTLQVNTIARATLLNPDGLVDKVTSIGRRGLIYLMSTGLAHFTYTDFCLPDSLRARGVLTIPNYHYRDDGLKIWAAIERFVSEIVSYYYPNDACVQQDSELQAWVGEIFAQAFLGRESSGFPSRLCTPGELVKYLTAIIFNCSAQHAAVNSGQHDFGAWMPNAPSSMRQPPPQTKGNTTMESYLETLPEVNTTCSNLLLFWLVSQEPKDQRPLGTYPDEHFTEEAPRQSIAAFQKCLAQISKDIRARNESLALPYAYLDPPLIENSVSI

Target ORF information:

RefSeq Version	NM_001105793.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105793.1

ORF Insert Sequence:

ATGGCAGTAT ATCGCCTGTG TGTGACCACT GGTTCCTACC TGAAGGCTGG CACATTGGAT 
AACATCTATG CTACACTGGT AGGCACCTGT GGTGAAAGCC CTAAGCAGAA GCTGGATCGT 
GTAGGCAGGG ACTTCGCCAC CGGATCGGTT CAGAAGTACA AGGTGCGCTG TGCATCAGAG 
CTGGGTGAGA TCTTGCTGTT GCGCTTACAC AAGGAGCGCT TTGCTTTCTT CTGCAAGGAT 
CCTTGGTACT GCAGTCGCAT CTGTGTCACT ACCCCAGATG GCTCTGTGGT TCACTTTCCC 
TGTTATCAGT GGATCGATGG CTACTGTACT GTGGAGCTTC GGCCAGGAAC AGCAAGAACC 
ATCTGCCAGG ATGCTCTTCC CCTCCTTCTG GATCACAGGA AGCGTGAACT CCAAGCCCGC 
CAAGAATGCT ACCGCTGGAA GATCTATGCC CCTGGTTTCC CTCGAATGGT GGATGTCAGC 
AGCTTTGAGG AGATGGAGTC AGATAAGAAA TTTGCCTTGA CCAAGACGGC GCCTTGTGCA 
GACCAGGATG ATAACTCTGG GAACCGGTAC CTGCCTGGCT TTCCTATGAA AGTTGACATC 
CCATCTCTGC TGCACATGGA GCCCAACATT CGCTACTCAG CCACCAAGAC AGCCTCACTC 
ATCTTCAACG CCCTTCCTGC ATCCTTGGGC ATGAAGATTC GAGGTCTGCT AGACCGCAAG 
GGCTCCTGGA AGAGGCTGGA TGACATCCGG AACATCTTCT GGTGTCATAA GACCTTCACT 
TCAGAGTATG TCACCGAGCA CTGGTGTGAG GACAGCTTCT TTGGGTACCA GTACCTGAAC 
GGTGTCAATC CCATCATGCT CCACTGCCTC TCCAGTCTGC CCAGCAAGCT GCCTGTCACC 
AATGACATGG TGGCACCTTT GCTGGGACCC GGCACCTGCC TGCAAACAGA GCTAGAGAGG 
GGGCACATCT TCTTAGCGGA CTACTGGATC CTGGCGGAGG CCCCAGTCCA TTGCCTAAAC 
GGCCGCCAAC AGTACGTAAC AGCTCCTCTC TGCCTGTTAT GGCTCAACCC ACAGGGGGTG 
CTGCTGCCGT TGGCAATCCA GCTCAGCCAG ATACCAGGGC CAGAGAGCCC CATCTTTCTA 
CCCACTGACT GCGAGTTGGA TTGGCTGCTG GCCAAGACGT GGGTGCGCAA CTCTGAGTTT 
TTGGTGCATG AGAACAACAC GCATTTTCTG TGCACGCATT TGCTCTGCGA GGCCTTCTCC 
ATGGCTACAC TGCGTCAGCT GCCCCTCTGT CATCCAGTCT ACAAGCTCCT GCTTCCTCAC 
ACTCGCTACA CACTGCAAGT GAACACCATC GCAAGGGCCA CACTGCTCAA CCCAGACGGC 
CTCGTGGACA AGGTCACATC CATCGGTAGG CGCGGCCTCA TCTACCTCAT GAGCACAGGG 
CTGGCCCACT TCACCTACAC GGATTTCTGC CTTCCGGATA GCCTACGGGC TCGTGGTGTC 
CTGACCATTC CCAACTACCA CTACCGAGAC GACGGCCTCA AGATCTGGGC GGCTATTGAG 
AGGTTTGTCT CCGAGATTGT GAGTTACTAT TACCCCAACG ATGCCTGTGT GCAGCAGGAC 
TCTGAGCTGC AGGCCTGGGT GGGTGAGATT TTTGCTCAGG CATTCCTCGG TCGGGAGAGT 
TCAGGCTTCC CAAGCAGGCT GTGCACCCCA GGAGAGCTCG TGAAGTATCT CACTGCAATC 
ATCTTTAACT GCTCCGCCCA GCACGCTGCA GTCAACAGTG GGCAGCACGA CTTTGGGGCC 
TGGATGCCCA ATGCCCCGTC ATCCATGAGG CAGCCTCCAC CTCAGACCAA GGGCAACACG 
ACAATGGAGA GTTACCTCGA AACCCTCCCA GAGGTGAACA CCACCTGTAG CAACCTTCTC 
CTCTTCTGGC TGGTCAGCCA AGAGCCAAAG GACCAGAGGC CTCTGGGCAC CTACCCAGAC 
GAACACTTCA CAGAGGAGGC CCCACGGCAA AGCATCGCAG CCTTCCAGAA GTGCCTGGCA 
CAGATCTCAA AGGACATCAG GGCACGCAAC GAGAGCCTGG CACTACCCTA TGCCTACTTG 
GATCCACCAC TCATTGAGAA CAGTGTCTCC ATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aloxe3 ( XM_017597088.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452577.1 Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa33248
Clone ID Related Accession (Same CDS sequence)	XM_017597088.1 , XM_006246619.2 , XM_017597087.1
Accession Version	XM_017597088.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	hydroperoxide isomerase ALOXE3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACGGTG TGATTCACGT GGATGATTCA CAGGTTCAGA AGTACAAGGT GCGCTGTGCA 
TCAGAGCTGG GTGAGATCTT GCTGTTGCGC TTACACAAGG AGCGCTTTGC TTTCTTCTGC 
AAGGATCCTT GGTACTGCAG TCGCATCTGT GTCACTACCC CAGATGGCTC TGTGGTTCAC 
TTTCCCTGTT ATCAGTGGAT CGATGGCTAC TGTACTGTGG AGCTTCGGCC AGGAACAGCA 
AGAACCATCT GCCAGGATGC TCTTCCCCTC CTTCTGGATC ACAGGAAGCG TGAACTCCAA 
GCCCGCCAAG AATGCTACCG CTGGAAGATC TATGCCCCTG GTTTCCCTCG AATGGTGGAT 
GTCAGCAGCT TTGAGGAGAT GGAGTCAGAT AAGAAATTTG CCTTGACCAA GACGGCGCCT 
TGTGCAGACC AGGATGATAA CTCTGGGAAC CGGTACCTGC CTGGCTTTCC TATGAAAGTT 
GACATCCCAT CTCTGCTGCA CATGGAGCCC AACATTCGCT ACTCAGCCAC CAAGACAGCC 
TCACTCATCT TCAACGCCCT TCCTGCATCC TTGGGCATGA AGATTCGAGG TCTGCTAGAC 
CGCAAGGGCT CCTGGAAGAG GCTGGATGAC ATCCGGAACA TCTTCTGGTG TCATAAGACC 
TTCACTTCAG AGTATGTCAC CGAGCACTGG TGTGAGGACA GCTTCTTTGG GTACCAGTAC 
CTGAACGGTG TCAATCCCAT CATGCTCCAC TGCCTCTCCA GTCTGCCCAG CAAGCTGCCT 
GTCACCAATG ACATGGTGGC ACCTTTGCTG GGACCCGGCA CCTGCCTGCA AACAGAGCTA 
GAGAGGGGGC ACATCTTCTT AGCGGACTAC TGGATCCTGG CGGAGGCCCC AGTCCATTGC 
CTAAACGGCC GCCAACAGTA CGTAACAGCT CCTCTCTGCC TGTTATGGCT CAACCCACAG 
GGGGTGCTGC TGCCGTTGGC AATCCAGCTC AGCCAGATAC CAGGGCCAGA GAGCCCCATC 
TTTCTACCCA CTGACTGCGA GTTGGATTGG CTGCTGGCCA AGACGTGGGT GCGCAACTCT 
GAGTTTTTGG TGCATGAGAA CAACACGCAT TTTCTGTGCA CGCATTTGCT CTGCGAGGCC 
TTCTCCATGG CTACACTGCG TCAGCTGCCC CTCTGTCATC CAGTCTACAA GCTCCTGCTT 
CCTCACACTC GCTACACACT GCAAGTGAAC ACCATCGCAA GGGCCACACT GCTCAACCCA 
GACGGCCTCG TGGACAAGGT CACATCCATC GGTAGGCGCG GCCTCATCTA CCTCATGAGC 
ACAGGGCTGG CCCACTTCAC CTACACGGAT TTCTGCCTTC CGGATAGCCT ACGGGCTCGT 
GGTGTCCTGA CCATTCCCAA CTACCACTAC CGAGACGACG GCCTCAAGAT CTGGGCGGCT 
ATTGAGAGGT TTGTCTCCGA GATTGTGAGT TACTATTACC CCAACGATGC CTGTGTGCAG 
CAGGACTCTG AGCTGCAGGC CTGGGTGGGT GAGATTTTTG CTCAGGCATT CCTCGGTCGG 
GAGAGTTCAG GCTTCCCAAG CAGGCTGTGC ACCCCAGGAG AGCTCGTGAA GTATCTCACT 
GCAATCATCT TTAACTGCTC CGCCCAGCAC GCTGCAGTCA ACAGTGGGCA GCACGACTTT 
GGGGCCTGGA TGCCCAATGC CCCGTCATCC ATGAGGCAGC CTCCACCTCA GACCAAGGGC 
AACACGACAA TGGAGAGTTA CCTCGAAACC CTCCCAGAGG TGAACACCAC CTGTAGCAAC 
CTTCTCCTCT TCTGGCTGGT CAGCCAAGAG CCAAAGGACC AGAGGCCTCT GGGCACCTAC 
CCAGACGAAC ACTTCACAGA GGAGGCCCCA CGGCAAAGCA TCGCAGCCTT CCAGAAGTGC 
CTGGCACAGA TCTCAAAGGA CATCAGGGCA CGCAACGAGA GCCTGGCACT ACCCTATGCC 
TACTTGGATC CACCACTCAT TGAGAACAGT GTCTCCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452577.1
CDS	122..2143
Translation	MYGVIHVDDSQVQKYKVRCASELGEILLLRLHKERFAFFCKDPWYCSRICVTTPDGSVVHFPCYQWIDGYCTVELRPGTARTICQDALPLLLDHRKRELQARQECYRWKIYAPGFPRMVDVSSFEEMESDKKFALTKTAPCADQDDNSGNRYLPGFPMKVDIPSLLHMEPNIRYSATKTASLIFNALPASLGMKIRGLLDRKGSWKRLDDIRNIFWCHKTFTSEYVTEHWCEDSFFGYQYLNGVNPIMLHCLSSLPSKLPVTNDMVAPLLGPGTCLQTELERGHIFLADYWILAEAPVHCLNGRQQYVTAPLCLLWLNPQGVLLPLAIQLSQIPGPESPIFLPTDCELDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFSMATLRQLPLCHPVYKLLLPHTRYTLQVNTIARATLLNPDGLVDKVTSIGRRGLIYLMSTGLAHFTYTDFCLPDSLRARGVLTIPNYHYRDDGLKIWAAIERFVSEIVSYYYPNDACVQQDSELQAWVGEIFAQAFLGRESSGFPSRLCTPGELVKYLTAIIFNCSAQHAAVNSGQHDFGAWMPNAPSSMRQPPPQTKGNTTMESYLETLPEVNTTCSNLLLFWLVSQEPKDQRPLGTYPDEHFTEEAPRQSIAAFQKCLAQISKDIRARNESLALPYAYLDPPLIENSVSI

Target ORF information:

RefSeq Version	XM_017597088.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597088.1

ORF Insert Sequence:

ATGTACGGTG TGATTCACGT GGATGATTCA CAGGTTCAGA AGTACAAGGT GCGCTGTGCA 
TCAGAGCTGG GTGAGATCTT GCTGTTGCGC TTACACAAGG AGCGCTTTGC TTTCTTCTGC 
AAGGATCCTT GGTACTGCAG TCGCATCTGT GTCACTACCC CAGATGGCTC TGTGGTTCAC 
TTTCCCTGTT ATCAGTGGAT CGATGGCTAC TGTACTGTGG AGCTTCGGCC AGGAACAGCA 
AGAACCATCT GCCAGGATGC TCTTCCCCTC CTTCTGGATC ACAGGAAGCG TGAACTCCAA 
GCCCGCCAAG AATGCTACCG CTGGAAGATC TATGCCCCTG GTTTCCCTCG AATGGTGGAT 
GTCAGCAGCT TTGAGGAGAT GGAGTCAGAT AAGAAATTTG CCTTGACCAA GACGGCGCCT 
TGTGCAGACC AGGATGATAA CTCTGGGAAC CGGTACCTGC CTGGCTTTCC TATGAAAGTT 
GACATCCCAT CTCTGCTGCA CATGGAGCCC AACATTCGCT ACTCAGCCAC CAAGACAGCC 
TCACTCATCT TCAACGCCCT TCCTGCATCC TTGGGCATGA AGATTCGAGG TCTGCTAGAC 
CGCAAGGGCT CCTGGAAGAG GCTGGATGAC ATCCGGAACA TCTTCTGGTG TCATAAGACC 
TTCACTTCAG AGTATGTCAC CGAGCACTGG TGTGAGGACA GCTTCTTTGG GTACCAGTAC 
CTGAACGGTG TCAATCCCAT CATGCTCCAC TGCCTCTCCA GTCTGCCCAG CAAGCTGCCT 
GTCACCAATG ACATGGTGGC ACCTTTGCTG GGACCCGGCA CCTGCCTGCA AACAGAGCTA 
GAGAGGGGGC ACATCTTCTT AGCGGACTAC TGGATCCTGG CGGAGGCCCC AGTCCATTGC 
CTAAACGGCC GCCAACAGTA CGTAACAGCT CCTCTCTGCC TGTTATGGCT CAACCCACAG 
GGGGTGCTGC TGCCGTTGGC AATCCAGCTC AGCCAGATAC CAGGGCCAGA GAGCCCCATC 
TTTCTACCCA CTGACTGCGA GTTGGATTGG CTGCTGGCCA AGACGTGGGT GCGCAACTCT 
GAGTTTTTGG TGCATGAGAA CAACACGCAT TTTCTGTGCA CGCATTTGCT CTGCGAGGCC 
TTCTCCATGG CTACACTGCG TCAGCTGCCC CTCTGTCATC CAGTCTACAA GCTCCTGCTT 
CCTCACACTC GCTACACACT GCAAGTGAAC ACCATCGCAA GGGCCACACT GCTCAACCCA 
GACGGCCTCG TGGACAAGGT CACATCCATC GGTAGGCGCG GCCTCATCTA CCTCATGAGC 
ACAGGGCTGG CCCACTTCAC CTACACGGAT TTCTGCCTTC CGGATAGCCT ACGGGCTCGT 
GGTGTCCTGA CCATTCCCAA CTACCACTAC CGAGACGACG GCCTCAAGAT CTGGGCGGCT 
ATTGAGAGGT TTGTCTCCGA GATTGTGAGT TACTATTACC CCAACGATGC CTGTGTGCAG 
CAGGACTCTG AGCTGCAGGC CTGGGTGGGT GAGATTTTTG CTCAGGCATT CCTCGGTCGG 
GAGAGTTCAG GCTTCCCAAG CAGGCTGTGC ACCCCAGGAG AGCTCGTGAA GTATCTCACT 
GCAATCATCT TTAACTGCTC CGCCCAGCAC GCTGCAGTCA ACAGTGGGCA GCACGACTTT 
GGGGCCTGGA TGCCCAATGC CCCGTCATCC ATGAGGCAGC CTCCACCTCA GACCAAGGGC 
AACACGACAA TGGAGAGTTA CCTCGAAACC CTCCCAGAGG TGAACACCAC CTGTAGCAAC 
CTTCTCCTCT TCTGGCTGGT CAGCCAAGAG CCAAAGGACC AGAGGCCTCT GGGCACCTAC 
CCAGACGAAC ACTTCACAGA GGAGGCCCCA CGGCAAAGCA TCGCAGCCTT CCAGAAGTGC 
CTGGCACAGA TCTCAAAGGA CATCAGGGCA CGCAACGAGA GCCTGGCACT ACCCTATGCC 
TACTTGGATC CACCACTCAT TGAGAACAGT GTCTCCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aloxe3 ( XM_006246619.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006246681.1 Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa33248
Clone ID Related Accession (Same CDS sequence)	XM_017597088.1 , XM_006246619.2 , XM_017597087.1
Accession Version	XM_006246619.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	hydroperoxide isomerase ALOXE3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006246619.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACGGTG TGATTCACGT GGATGATTCA CAGGTTCAGA AGTACAAGGT GCGCTGTGCA 
TCAGAGCTGG GTGAGATCTT GCTGTTGCGC TTACACAAGG AGCGCTTTGC TTTCTTCTGC 
AAGGATCCTT GGTACTGCAG TCGCATCTGT GTCACTACCC CAGATGGCTC TGTGGTTCAC 
TTTCCCTGTT ATCAGTGGAT CGATGGCTAC TGTACTGTGG AGCTTCGGCC AGGAACAGCA 
AGAACCATCT GCCAGGATGC TCTTCCCCTC CTTCTGGATC ACAGGAAGCG TGAACTCCAA 
GCCCGCCAAG AATGCTACCG CTGGAAGATC TATGCCCCTG GTTTCCCTCG AATGGTGGAT 
GTCAGCAGCT TTGAGGAGAT GGAGTCAGAT AAGAAATTTG CCTTGACCAA GACGGCGCCT 
TGTGCAGACC AGGATGATAA CTCTGGGAAC CGGTACCTGC CTGGCTTTCC TATGAAAGTT 
GACATCCCAT CTCTGCTGCA CATGGAGCCC AACATTCGCT ACTCAGCCAC CAAGACAGCC 
TCACTCATCT TCAACGCCCT TCCTGCATCC TTGGGCATGA AGATTCGAGG TCTGCTAGAC 
CGCAAGGGCT CCTGGAAGAG GCTGGATGAC ATCCGGAACA TCTTCTGGTG TCATAAGACC 
TTCACTTCAG AGTATGTCAC CGAGCACTGG TGTGAGGACA GCTTCTTTGG GTACCAGTAC 
CTGAACGGTG TCAATCCCAT CATGCTCCAC TGCCTCTCCA GTCTGCCCAG CAAGCTGCCT 
GTCACCAATG ACATGGTGGC ACCTTTGCTG GGACCCGGCA CCTGCCTGCA AACAGAGCTA 
GAGAGGGGGC ACATCTTCTT AGCGGACTAC TGGATCCTGG CGGAGGCCCC AGTCCATTGC 
CTAAACGGCC GCCAACAGTA CGTAACAGCT CCTCTCTGCC TGTTATGGCT CAACCCACAG 
GGGGTGCTGC TGCCGTTGGC AATCCAGCTC AGCCAGATAC CAGGGCCAGA GAGCCCCATC 
TTTCTACCCA CTGACTGCGA GTTGGATTGG CTGCTGGCCA AGACGTGGGT GCGCAACTCT 
GAGTTTTTGG TGCATGAGAA CAACACGCAT TTTCTGTGCA CGCATTTGCT CTGCGAGGCC 
TTCTCCATGG CTACACTGCG TCAGCTGCCC CTCTGTCATC CAGTCTACAA GCTCCTGCTT 
CCTCACACTC GCTACACACT GCAAGTGAAC ACCATCGCAA GGGCCACACT GCTCAACCCA 
GACGGCCTCG TGGACAAGGT CACATCCATC GGTAGGCGCG GCCTCATCTA CCTCATGAGC 
ACAGGGCTGG CCCACTTCAC CTACACGGAT TTCTGCCTTC CGGATAGCCT ACGGGCTCGT 
GGTGTCCTGA CCATTCCCAA CTACCACTAC CGAGACGACG GCCTCAAGAT CTGGGCGGCT 
ATTGAGAGGT TTGTCTCCGA GATTGTGAGT TACTATTACC CCAACGATGC CTGTGTGCAG 
CAGGACTCTG AGCTGCAGGC CTGGGTGGGT GAGATTTTTG CTCAGGCATT CCTCGGTCGG 
GAGAGTTCAG GCTTCCCAAG CAGGCTGTGC ACCCCAGGAG AGCTCGTGAA GTATCTCACT 
GCAATCATCT TTAACTGCTC CGCCCAGCAC GCTGCAGTCA ACAGTGGGCA GCACGACTTT 
GGGGCCTGGA TGCCCAATGC CCCGTCATCC ATGAGGCAGC CTCCACCTCA GACCAAGGGC 
AACACGACAA TGGAGAGTTA CCTCGAAACC CTCCCAGAGG TGAACACCAC CTGTAGCAAC 
CTTCTCCTCT TCTGGCTGGT CAGCCAAGAG CCAAAGGACC AGAGGCCTCT GGGCACCTAC 
CCAGACGAAC ACTTCACAGA GGAGGCCCCA CGGCAAAGCA TCGCAGCCTT CCAGAAGTGC 
CTGGCACAGA TCTCAAAGGA CATCAGGGCA CGCAACGAGA GCCTGGCACT ACCCTATGCC 
TACTTGGATC CACCACTCAT TGAGAACAGT GTCTCCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006246681.1
CDS	213..2234
Translation	MYGVIHVDDSQVQKYKVRCASELGEILLLRLHKERFAFFCKDPWYCSRICVTTPDGSVVHFPCYQWIDGYCTVELRPGTARTICQDALPLLLDHRKRELQARQECYRWKIYAPGFPRMVDVSSFEEMESDKKFALTKTAPCADQDDNSGNRYLPGFPMKVDIPSLLHMEPNIRYSATKTASLIFNALPASLGMKIRGLLDRKGSWKRLDDIRNIFWCHKTFTSEYVTEHWCEDSFFGYQYLNGVNPIMLHCLSSLPSKLPVTNDMVAPLLGPGTCLQTELERGHIFLADYWILAEAPVHCLNGRQQYVTAPLCLLWLNPQGVLLPLAIQLSQIPGPESPIFLPTDCELDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFSMATLRQLPLCHPVYKLLLPHTRYTLQVNTIARATLLNPDGLVDKVTSIGRRGLIYLMSTGLAHFTYTDFCLPDSLRARGVLTIPNYHYRDDGLKIWAAIERFVSEIVSYYYPNDACVQQDSELQAWVGEIFAQAFLGRESSGFPSRLCTPGELVKYLTAIIFNCSAQHAAVNSGQHDFGAWMPNAPSSMRQPPPQTKGNTTMESYLETLPEVNTTCSNLLLFWLVSQEPKDQRPLGTYPDEHFTEEAPRQSIAAFQKCLAQISKDIRARNESLALPYAYLDPPLIENSVSI

Target ORF information:

RefSeq Version	XM_006246619.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006246619.2

ORF Insert Sequence:

ATGTACGGTG TGATTCACGT GGATGATTCA CAGGTTCAGA AGTACAAGGT GCGCTGTGCA 
TCAGAGCTGG GTGAGATCTT GCTGTTGCGC TTACACAAGG AGCGCTTTGC TTTCTTCTGC 
AAGGATCCTT GGTACTGCAG TCGCATCTGT GTCACTACCC CAGATGGCTC TGTGGTTCAC 
TTTCCCTGTT ATCAGTGGAT CGATGGCTAC TGTACTGTGG AGCTTCGGCC AGGAACAGCA 
AGAACCATCT GCCAGGATGC TCTTCCCCTC CTTCTGGATC ACAGGAAGCG TGAACTCCAA 
GCCCGCCAAG AATGCTACCG CTGGAAGATC TATGCCCCTG GTTTCCCTCG AATGGTGGAT 
GTCAGCAGCT TTGAGGAGAT GGAGTCAGAT AAGAAATTTG CCTTGACCAA GACGGCGCCT 
TGTGCAGACC AGGATGATAA CTCTGGGAAC CGGTACCTGC CTGGCTTTCC TATGAAAGTT 
GACATCCCAT CTCTGCTGCA CATGGAGCCC AACATTCGCT ACTCAGCCAC CAAGACAGCC 
TCACTCATCT TCAACGCCCT TCCTGCATCC TTGGGCATGA AGATTCGAGG TCTGCTAGAC 
CGCAAGGGCT CCTGGAAGAG GCTGGATGAC ATCCGGAACA TCTTCTGGTG TCATAAGACC 
TTCACTTCAG AGTATGTCAC CGAGCACTGG TGTGAGGACA GCTTCTTTGG GTACCAGTAC 
CTGAACGGTG TCAATCCCAT CATGCTCCAC TGCCTCTCCA GTCTGCCCAG CAAGCTGCCT 
GTCACCAATG ACATGGTGGC ACCTTTGCTG GGACCCGGCA CCTGCCTGCA AACAGAGCTA 
GAGAGGGGGC ACATCTTCTT AGCGGACTAC TGGATCCTGG CGGAGGCCCC AGTCCATTGC 
CTAAACGGCC GCCAACAGTA CGTAACAGCT CCTCTCTGCC TGTTATGGCT CAACCCACAG 
GGGGTGCTGC TGCCGTTGGC AATCCAGCTC AGCCAGATAC CAGGGCCAGA GAGCCCCATC 
TTTCTACCCA CTGACTGCGA GTTGGATTGG CTGCTGGCCA AGACGTGGGT GCGCAACTCT 
GAGTTTTTGG TGCATGAGAA CAACACGCAT TTTCTGTGCA CGCATTTGCT CTGCGAGGCC 
TTCTCCATGG CTACACTGCG TCAGCTGCCC CTCTGTCATC CAGTCTACAA GCTCCTGCTT 
CCTCACACTC GCTACACACT GCAAGTGAAC ACCATCGCAA GGGCCACACT GCTCAACCCA 
GACGGCCTCG TGGACAAGGT CACATCCATC GGTAGGCGCG GCCTCATCTA CCTCATGAGC 
ACAGGGCTGG CCCACTTCAC CTACACGGAT TTCTGCCTTC CGGATAGCCT ACGGGCTCGT 
GGTGTCCTGA CCATTCCCAA CTACCACTAC CGAGACGACG GCCTCAAGAT CTGGGCGGCT 
ATTGAGAGGT TTGTCTCCGA GATTGTGAGT TACTATTACC CCAACGATGC CTGTGTGCAG 
CAGGACTCTG AGCTGCAGGC CTGGGTGGGT GAGATTTTTG CTCAGGCATT CCTCGGTCGG 
GAGAGTTCAG GCTTCCCAAG CAGGCTGTGC ACCCCAGGAG AGCTCGTGAA GTATCTCACT 
GCAATCATCT TTAACTGCTC CGCCCAGCAC GCTGCAGTCA ACAGTGGGCA GCACGACTTT 
GGGGCCTGGA TGCCCAATGC CCCGTCATCC ATGAGGCAGC CTCCACCTCA GACCAAGGGC 
AACACGACAA TGGAGAGTTA CCTCGAAACC CTCCCAGAGG TGAACACCAC CTGTAGCAAC 
CTTCTCCTCT TCTGGCTGGT CAGCCAAGAG CCAAAGGACC AGAGGCCTCT GGGCACCTAC 
CCAGACGAAC ACTTCACAGA GGAGGCCCCA CGGCAAAGCA TCGCAGCCTT CCAGAAGTGC 
CTGGCACAGA TCTCAAAGGA CATCAGGGCA CGCAACGAGA GCCTGGCACT ACCCTATGCC 
TACTTGGATC CACCACTCAT TGAGAACAGT GTCTCCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aloxe3 ( XM_017597087.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452576.1 Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa33248
Clone ID Related Accession (Same CDS sequence)	XM_017597088.1 , XM_006246619.2 , XM_017597087.1
Accession Version	XM_017597087.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	hydroperoxide isomerase ALOXE3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACGGTG TGATTCACGT GGATGATTCA CAGGTTCAGA AGTACAAGGT GCGCTGTGCA 
TCAGAGCTGG GTGAGATCTT GCTGTTGCGC TTACACAAGG AGCGCTTTGC TTTCTTCTGC 
AAGGATCCTT GGTACTGCAG TCGCATCTGT GTCACTACCC CAGATGGCTC TGTGGTTCAC 
TTTCCCTGTT ATCAGTGGAT CGATGGCTAC TGTACTGTGG AGCTTCGGCC AGGAACAGCA 
AGAACCATCT GCCAGGATGC TCTTCCCCTC CTTCTGGATC ACAGGAAGCG TGAACTCCAA 
GCCCGCCAAG AATGCTACCG CTGGAAGATC TATGCCCCTG GTTTCCCTCG AATGGTGGAT 
GTCAGCAGCT TTGAGGAGAT GGAGTCAGAT AAGAAATTTG CCTTGACCAA GACGGCGCCT 
TGTGCAGACC AGGATGATAA CTCTGGGAAC CGGTACCTGC CTGGCTTTCC TATGAAAGTT 
GACATCCCAT CTCTGCTGCA CATGGAGCCC AACATTCGCT ACTCAGCCAC CAAGACAGCC 
TCACTCATCT TCAACGCCCT TCCTGCATCC TTGGGCATGA AGATTCGAGG TCTGCTAGAC 
CGCAAGGGCT CCTGGAAGAG GCTGGATGAC ATCCGGAACA TCTTCTGGTG TCATAAGACC 
TTCACTTCAG AGTATGTCAC CGAGCACTGG TGTGAGGACA GCTTCTTTGG GTACCAGTAC 
CTGAACGGTG TCAATCCCAT CATGCTCCAC TGCCTCTCCA GTCTGCCCAG CAAGCTGCCT 
GTCACCAATG ACATGGTGGC ACCTTTGCTG GGACCCGGCA CCTGCCTGCA AACAGAGCTA 
GAGAGGGGGC ACATCTTCTT AGCGGACTAC TGGATCCTGG CGGAGGCCCC AGTCCATTGC 
CTAAACGGCC GCCAACAGTA CGTAACAGCT CCTCTCTGCC TGTTATGGCT CAACCCACAG 
GGGGTGCTGC TGCCGTTGGC AATCCAGCTC AGCCAGATAC CAGGGCCAGA GAGCCCCATC 
TTTCTACCCA CTGACTGCGA GTTGGATTGG CTGCTGGCCA AGACGTGGGT GCGCAACTCT 
GAGTTTTTGG TGCATGAGAA CAACACGCAT TTTCTGTGCA CGCATTTGCT CTGCGAGGCC 
TTCTCCATGG CTACACTGCG TCAGCTGCCC CTCTGTCATC CAGTCTACAA GCTCCTGCTT 
CCTCACACTC GCTACACACT GCAAGTGAAC ACCATCGCAA GGGCCACACT GCTCAACCCA 
GACGGCCTCG TGGACAAGGT CACATCCATC GGTAGGCGCG GCCTCATCTA CCTCATGAGC 
ACAGGGCTGG CCCACTTCAC CTACACGGAT TTCTGCCTTC CGGATAGCCT ACGGGCTCGT 
GGTGTCCTGA CCATTCCCAA CTACCACTAC CGAGACGACG GCCTCAAGAT CTGGGCGGCT 
ATTGAGAGGT TTGTCTCCGA GATTGTGAGT TACTATTACC CCAACGATGC CTGTGTGCAG 
CAGGACTCTG AGCTGCAGGC CTGGGTGGGT GAGATTTTTG CTCAGGCATT CCTCGGTCGG 
GAGAGTTCAG GCTTCCCAAG CAGGCTGTGC ACCCCAGGAG AGCTCGTGAA GTATCTCACT 
GCAATCATCT TTAACTGCTC CGCCCAGCAC GCTGCAGTCA ACAGTGGGCA GCACGACTTT 
GGGGCCTGGA TGCCCAATGC CCCGTCATCC ATGAGGCAGC CTCCACCTCA GACCAAGGGC 
AACACGACAA TGGAGAGTTA CCTCGAAACC CTCCCAGAGG TGAACACCAC CTGTAGCAAC 
CTTCTCCTCT TCTGGCTGGT CAGCCAAGAG CCAAAGGACC AGAGGCCTCT GGGCACCTAC 
CCAGACGAAC ACTTCACAGA GGAGGCCCCA CGGCAAAGCA TCGCAGCCTT CCAGAAGTGC 
CTGGCACAGA TCTCAAAGGA CATCAGGGCA CGCAACGAGA GCCTGGCACT ACCCTATGCC 
TACTTGGATC CACCACTCAT TGAGAACAGT GTCTCCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452576.1
CDS	150..2171
Translation	MYGVIHVDDSQVQKYKVRCASELGEILLLRLHKERFAFFCKDPWYCSRICVTTPDGSVVHFPCYQWIDGYCTVELRPGTARTICQDALPLLLDHRKRELQARQECYRWKIYAPGFPRMVDVSSFEEMESDKKFALTKTAPCADQDDNSGNRYLPGFPMKVDIPSLLHMEPNIRYSATKTASLIFNALPASLGMKIRGLLDRKGSWKRLDDIRNIFWCHKTFTSEYVTEHWCEDSFFGYQYLNGVNPIMLHCLSSLPSKLPVTNDMVAPLLGPGTCLQTELERGHIFLADYWILAEAPVHCLNGRQQYVTAPLCLLWLNPQGVLLPLAIQLSQIPGPESPIFLPTDCELDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFSMATLRQLPLCHPVYKLLLPHTRYTLQVNTIARATLLNPDGLVDKVTSIGRRGLIYLMSTGLAHFTYTDFCLPDSLRARGVLTIPNYHYRDDGLKIWAAIERFVSEIVSYYYPNDACVQQDSELQAWVGEIFAQAFLGRESSGFPSRLCTPGELVKYLTAIIFNCSAQHAAVNSGQHDFGAWMPNAPSSMRQPPPQTKGNTTMESYLETLPEVNTTCSNLLLFWLVSQEPKDQRPLGTYPDEHFTEEAPRQSIAAFQKCLAQISKDIRARNESLALPYAYLDPPLIENSVSI

Target ORF information:

RefSeq Version	XM_017597087.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597087.1

ORF Insert Sequence:

ATGTACGGTG TGATTCACGT GGATGATTCA CAGGTTCAGA AGTACAAGGT GCGCTGTGCA 
TCAGAGCTGG GTGAGATCTT GCTGTTGCGC TTACACAAGG AGCGCTTTGC TTTCTTCTGC 
AAGGATCCTT GGTACTGCAG TCGCATCTGT GTCACTACCC CAGATGGCTC TGTGGTTCAC 
TTTCCCTGTT ATCAGTGGAT CGATGGCTAC TGTACTGTGG AGCTTCGGCC AGGAACAGCA 
AGAACCATCT GCCAGGATGC TCTTCCCCTC CTTCTGGATC ACAGGAAGCG TGAACTCCAA 
GCCCGCCAAG AATGCTACCG CTGGAAGATC TATGCCCCTG GTTTCCCTCG AATGGTGGAT 
GTCAGCAGCT TTGAGGAGAT GGAGTCAGAT AAGAAATTTG CCTTGACCAA GACGGCGCCT 
TGTGCAGACC AGGATGATAA CTCTGGGAAC CGGTACCTGC CTGGCTTTCC TATGAAAGTT 
GACATCCCAT CTCTGCTGCA CATGGAGCCC AACATTCGCT ACTCAGCCAC CAAGACAGCC 
TCACTCATCT TCAACGCCCT TCCTGCATCC TTGGGCATGA AGATTCGAGG TCTGCTAGAC 
CGCAAGGGCT CCTGGAAGAG GCTGGATGAC ATCCGGAACA TCTTCTGGTG TCATAAGACC 
TTCACTTCAG AGTATGTCAC CGAGCACTGG TGTGAGGACA GCTTCTTTGG GTACCAGTAC 
CTGAACGGTG TCAATCCCAT CATGCTCCAC TGCCTCTCCA GTCTGCCCAG CAAGCTGCCT 
GTCACCAATG ACATGGTGGC ACCTTTGCTG GGACCCGGCA CCTGCCTGCA AACAGAGCTA 
GAGAGGGGGC ACATCTTCTT AGCGGACTAC TGGATCCTGG CGGAGGCCCC AGTCCATTGC 
CTAAACGGCC GCCAACAGTA CGTAACAGCT CCTCTCTGCC TGTTATGGCT CAACCCACAG 
GGGGTGCTGC TGCCGTTGGC AATCCAGCTC AGCCAGATAC CAGGGCCAGA GAGCCCCATC 
TTTCTACCCA CTGACTGCGA GTTGGATTGG CTGCTGGCCA AGACGTGGGT GCGCAACTCT 
GAGTTTTTGG TGCATGAGAA CAACACGCAT TTTCTGTGCA CGCATTTGCT CTGCGAGGCC 
TTCTCCATGG CTACACTGCG TCAGCTGCCC CTCTGTCATC CAGTCTACAA GCTCCTGCTT 
CCTCACACTC GCTACACACT GCAAGTGAAC ACCATCGCAA GGGCCACACT GCTCAACCCA 
GACGGCCTCG TGGACAAGGT CACATCCATC GGTAGGCGCG GCCTCATCTA CCTCATGAGC 
ACAGGGCTGG CCCACTTCAC CTACACGGAT TTCTGCCTTC CGGATAGCCT ACGGGCTCGT 
GGTGTCCTGA CCATTCCCAA CTACCACTAC CGAGACGACG GCCTCAAGAT CTGGGCGGCT 
ATTGAGAGGT TTGTCTCCGA GATTGTGAGT TACTATTACC CCAACGATGC CTGTGTGCAG 
CAGGACTCTG AGCTGCAGGC CTGGGTGGGT GAGATTTTTG CTCAGGCATT CCTCGGTCGG 
GAGAGTTCAG GCTTCCCAAG CAGGCTGTGC ACCCCAGGAG AGCTCGTGAA GTATCTCACT 
GCAATCATCT TTAACTGCTC CGCCCAGCAC GCTGCAGTCA ACAGTGGGCA GCACGACTTT 
GGGGCCTGGA TGCCCAATGC CCCGTCATCC ATGAGGCAGC CTCCACCTCA GACCAAGGGC 
AACACGACAA TGGAGAGTTA CCTCGAAACC CTCCCAGAGG TGAACACCAC CTGTAGCAAC 
CTTCTCCTCT TCTGGCTGGT CAGCCAAGAG CCAAAGGACC AGAGGCCTCT GGGCACCTAC 
CCAGACGAAC ACTTCACAGA GGAGGCCCCA CGGCAAAGCA TCGCAGCCTT CCAGAAGTGC 
CTGGCACAGA TCTCAAAGGA CATCAGGGCA CGCAACGAGA GCCTGGCACT ACCCTATGCC 
TACTTGGATC CACCACTCAT TGAGAACAGT GTCTCCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aloxe3 ( XM_017597089.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452578.1 Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa57220
Clone ID Related Accession (Same CDS sequence)	XM_017597089.1
Accession Version	XM_017597089.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1989bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	hydroperoxide isomerase ALOXE3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGTAT ATCGCCTGTG TGTGACCACT GGTTCCTACC TGAAGGCTGG CACATTGGAT 
AACATCTATG CTACACTGGT AGGCACCTGT GGTGAAAGCC CTAAGCAGAA GCTGGATCGT 
GTAGGCAGGG ACTTCGCCAC CGGATCGGTT CAGAAGTACA AGGTGCGCTG TGCATCAGAG 
CTGGGTGAGA TCTTGCTGTT GCGCTTACAC AAGGAGCGCT TTGCTTTCTT CTGCAAGGAT 
CCTTGGTACT GCAGTCGCAT CTGTGTCACT ACCCCAGATG GCTCTGTGGT TCACTTTCCC 
TGTTATCAGT GGATCGATGG CTACTGTACT GTGGAGCTTC GGCCAGGAAC AGCAAGAACC 
ATCTGCCAGG ATGCTCTTCC CCTCCTTCTG GATCACAGGA AGCGTGAACT CCAAGCCCGC 
CAAGAATGCT ACCGCTGGAA GATCTATGCC CCTGGTTTCC CTCGAATGGT GGATGTCAGC 
AGCTTTGAGG AGATGGAGTC AGATAAGAAA TTTGCCTTGA CCAAGACGGC GCCTTGTGCA 
GACCAGGATG ATAACTCTGG GAACCGGTAC CTGCCTGGCT TTCCTATGAA AGTTGACATC 
CCATCTCTGC TGCACATGGA GCCCAACATT CGCTACTCAG CCACCAAGAC AGCCTCACTC 
ATCTTCAACG CCCTTCCTGC ATCCTTGGGC ATGAAGATTC GAGGTCTGCT AGACCGCAAG 
GGCTCCTGGA AGAGGCTGGA TGACATCCGG AACATCTTCT GGTGTCATAA GACCTTCACT 
TCAGAGTATG TCACCGAGCA CTGGTGTGAG GACAGCTTCT TTGGGTACCA GTACCTGAAC 
GGTGTCAATC CCATCATGCT CCACTGCCTC TCCAGTCTGC CCAGCAAGCT GCCTGTCACC 
AATGACATGG TGGCACCTTT GCTGGGACCC GGCACCTGCC TGCAAACAGA GCTAGAGAGG 
GGGCACATCT TCTTAGCGGA CTACTGGATC CTGGCGGAGG CCCCAGTCCA TTGCCTAAAC 
GGCCGCCAAC AGTACGTAAC AGCTCCTCTC TGCCTGTTAT GGCTCAACCC ACAGGGGGTG 
CTGCTGCCGT TGGCAATCCA GCTCAGCCAG ATACCAGGGC CAGAGAGCCC CATCTTTCTA 
CCCACTGACT GCGAGTTGGA TTGGCTGCTG GCCAAGACGT GGGTGCGCAA CTCTGAGTTT 
TTGGTGCATG AGAACAACAC GCATTTTCTG TGCACGCATT TGCTCTGCGA GGCCTTCTCC 
ATGGCTACAC TGCGTCAGCT GCCCCTCTGT CATCCAGTCT ACAAGCTCCT GCTTCCTCAC 
ACTCGCTACA CACTGCAAGT GAACACCATC GCAAGGGCCA CACTGCTCAA CCCAGACGGC 
CTCGTGGACA AGGTCACATC CATCGGTAGG CGCGGCCTCA TCTACCTCAT GAGCACAGGG 
CTGGCCCACT TCACCTACAC GGATTTCTGC CTTCCGGATA GCCTACGGGC TCGTGGTGTC 
CTGACCATTC CCAACTACCA CTACCGAGAC GACGGCCTCA AGATCTGGGC GGCTATTGAG 
AGGTTTGTCT CCGAGATTGT GAGTTACTAT TACCCCAACG ATGCCTGTGT GCAGCAGGAC 
TCTGAGCTGC AGGCCTGGGT GGGTGAGATT TTTGCTCAGG CATTCCTCGG TCGGGAGAGT 
TCAGGCTTCC CAAGCAGGCT GTGCACCCCA GGAGAGCTCG TGAAGTATCT CACTGCAATC 
ATCTTTAACT GCTCCGCCCA GCACGCTGCA GTCAACAGTG GGCAGCACGA CTTTGGGGCC 
TGGATGCCCA ATGCCCCGTC ATCCATGAGG CAGCCTCCAC CTCAGACCAA GGGCAACACG 
ACAATGGAGA GTTACCTCGA AACCCTCCCA GAGGTGAACA CCACCTGTAG CAACCTTCTC 
CTCTTCTGGC TGGTCAGCCA AGAGCCAAAG GACCAGGAAA TGATACTCGA TCTCCAAGGA 
CACACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452578.1
CDS	753..2741
Translation	MAVYRLCVTTGSYLKAGTLDNIYATLVGTCGESPKQKLDRVGRDFATGSVQKYKVRCASELGEILLLRLHKERFAFFCKDPWYCSRICVTTPDGSVVHFPCYQWIDGYCTVELRPGTARTICQDALPLLLDHRKRELQARQECYRWKIYAPGFPRMVDVSSFEEMESDKKFALTKTAPCADQDDNSGNRYLPGFPMKVDIPSLLHMEPNIRYSATKTASLIFNALPASLGMKIRGLLDRKGSWKRLDDIRNIFWCHKTFTSEYVTEHWCEDSFFGYQYLNGVNPIMLHCLSSLPSKLPVTNDMVAPLLGPGTCLQTELERGHIFLADYWILAEAPVHCLNGRQQYVTAPLCLLWLNPQGVLLPLAIQLSQIPGPESPIFLPTDCELDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFSMATLRQLPLCHPVYKLLLPHTRYTLQVNTIARATLLNPDGLVDKVTSIGRRGLIYLMSTGLAHFTYTDFCLPDSLRARGVLTIPNYHYRDDGLKIWAAIERFVSEIVSYYYPNDACVQQDSELQAWVGEIFAQAFLGRESSGFPSRLCTPGELVKYLTAIIFNCSAQHAAVNSGQHDFGAWMPNAPSSMRQPPPQTKGNTTMESYLETLPEVNTTCSNLLLFWLVSQEPKDQEMILDLQGHT

Target ORF information:

RefSeq Version	XM_017597089.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus arachidonate lipoxygenase 3 (Aloxe3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597089.1

ORF Insert Sequence:

ATGGCAGTAT ATCGCCTGTG TGTGACCACT GGTTCCTACC TGAAGGCTGG CACATTGGAT 
AACATCTATG CTACACTGGT AGGCACCTGT GGTGAAAGCC CTAAGCAGAA GCTGGATCGT 
GTAGGCAGGG ACTTCGCCAC CGGATCGGTT CAGAAGTACA AGGTGCGCTG TGCATCAGAG 
CTGGGTGAGA TCTTGCTGTT GCGCTTACAC AAGGAGCGCT TTGCTTTCTT CTGCAAGGAT 
CCTTGGTACT GCAGTCGCAT CTGTGTCACT ACCCCAGATG GCTCTGTGGT TCACTTTCCC 
TGTTATCAGT GGATCGATGG CTACTGTACT GTGGAGCTTC GGCCAGGAAC AGCAAGAACC 
ATCTGCCAGG ATGCTCTTCC CCTCCTTCTG GATCACAGGA AGCGTGAACT CCAAGCCCGC 
CAAGAATGCT ACCGCTGGAA GATCTATGCC CCTGGTTTCC CTCGAATGGT GGATGTCAGC 
AGCTTTGAGG AGATGGAGTC AGATAAGAAA TTTGCCTTGA CCAAGACGGC GCCTTGTGCA 
GACCAGGATG ATAACTCTGG GAACCGGTAC CTGCCTGGCT TTCCTATGAA AGTTGACATC 
CCATCTCTGC TGCACATGGA GCCCAACATT CGCTACTCAG CCACCAAGAC AGCCTCACTC 
ATCTTCAACG CCCTTCCTGC ATCCTTGGGC ATGAAGATTC GAGGTCTGCT AGACCGCAAG 
GGCTCCTGGA AGAGGCTGGA TGACATCCGG AACATCTTCT GGTGTCATAA GACCTTCACT 
TCAGAGTATG TCACCGAGCA CTGGTGTGAG GACAGCTTCT TTGGGTACCA GTACCTGAAC 
GGTGTCAATC CCATCATGCT CCACTGCCTC TCCAGTCTGC CCAGCAAGCT GCCTGTCACC 
AATGACATGG TGGCACCTTT GCTGGGACCC GGCACCTGCC TGCAAACAGA GCTAGAGAGG 
GGGCACATCT TCTTAGCGGA CTACTGGATC CTGGCGGAGG CCCCAGTCCA TTGCCTAAAC 
GGCCGCCAAC AGTACGTAAC AGCTCCTCTC TGCCTGTTAT GGCTCAACCC ACAGGGGGTG 
CTGCTGCCGT TGGCAATCCA GCTCAGCCAG ATACCAGGGC CAGAGAGCCC CATCTTTCTA 
CCCACTGACT GCGAGTTGGA TTGGCTGCTG GCCAAGACGT GGGTGCGCAA CTCTGAGTTT 
TTGGTGCATG AGAACAACAC GCATTTTCTG TGCACGCATT TGCTCTGCGA GGCCTTCTCC 
ATGGCTACAC TGCGTCAGCT GCCCCTCTGT CATCCAGTCT ACAAGCTCCT GCTTCCTCAC 
ACTCGCTACA CACTGCAAGT GAACACCATC GCAAGGGCCA CACTGCTCAA CCCAGACGGC 
CTCGTGGACA AGGTCACATC CATCGGTAGG CGCGGCCTCA TCTACCTCAT GAGCACAGGG 
CTGGCCCACT TCACCTACAC GGATTTCTGC CTTCCGGATA GCCTACGGGC TCGTGGTGTC 
CTGACCATTC CCAACTACCA CTACCGAGAC GACGGCCTCA AGATCTGGGC GGCTATTGAG 
AGGTTTGTCT CCGAGATTGT GAGTTACTAT TACCCCAACG ATGCCTGTGT GCAGCAGGAC 
TCTGAGCTGC AGGCCTGGGT GGGTGAGATT TTTGCTCAGG CATTCCTCGG TCGGGAGAGT 
TCAGGCTTCC CAAGCAGGCT GTGCACCCCA GGAGAGCTCG TGAAGTATCT CACTGCAATC 
ATCTTTAACT GCTCCGCCCA GCACGCTGCA GTCAACAGTG GGCAGCACGA CTTTGGGGCC 
TGGATGCCCA ATGCCCCGTC ATCCATGAGG CAGCCTCCAC CTCAGACCAA GGGCAACACG 
ACAATGGAGA GTTACCTCGA AACCCTCCCA GAGGTGAACA CCACCTGTAG CAACCTTCTC 
CTCTTCTGGC TGGTCAGCCA AGAGCCAAAG GACCAGGAAA TGATACTCGA TCTCCAAGGA 
CACACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology27(5)1939-49(2013 May)
Gregus AM,Dumlao DS,Wei SC,Norris PC,Catella LC,Meyerstein FG,Buczynski MW,Steinauer JJ,Fitzsimmons BL,Yaksh TL,Dennis EA

Role of tomato lipoxygenase D in wound-induced jasmonate biosynthesis and plant immunity to insect herbivores.
PLoS genetics9(12)e1003964(2013)
Yan L,Zhai Q,Wei J,Li S,Wang B,Huang T,Du M,Sun J,Kang L,Li CB,Li C

Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation.
The Journal of investigative dermatology133(1)172-80(2013 Jan)
Krieg P,Rosenberger S,de Juanes S,Latzko S,Hou J,Dick A,Kloz U,van der Hoeven F,Hausser I,Esposito I,Rauh M,Schneider H

Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope.
The Journal of biological chemistry286(27)24046-56(2011 Jul)
Zheng Y,Yin H,Boeglin WE,Elias PM,Crumrine D,Beier DR,Brash AR

Dioxygenase activity of epidermal lipoxygenase-3 unveiled: typical and atypical features of its catalytic activity with natural and synthetic polyunsaturated fatty acids.
The Journal of biological chemistry285(51)39866-75(2010 Dec)
Zheng Y,Brash AR